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Entry ID Original Release date Data summary Entry Title Citation Title Authors
27835 2019-05-22 Chemical Shifts: 1 set
HRdup moPrP 118-231 Nascent beta structure in the Elongated Hydrophobic Region of a Gerstmann-Straussler-Scheinker PrP Allele Download bibtex for citation iamge Brian D Sykes, David Westaway, Peter C Holmes, Ze-Lin Fu
30371 2018-11-06 Chemical Shifts: 1 set
Spectral_peak_list: 1 set
NMR Structural and biophysical functional analysis of intracellular loop 5 of the NHE1 isoform of the Na+/H+ exchanger. Diverse residues of intracellular loop 5 of the Na+/H+ exchanger modulate proton sensing, expression, activity and targeting Download bibtex for citation iamge Brian D Sykes, Debajyoti Dutta, Kaitlyn Towle, Ka Yee Y Wong, Larry Fliegel, Ryan McKay, Sicheng Quan, Xiuju Li, Yesmine Elloumi, Yongsheng Liu
25810 2016-07-20 Chemical Shifts: 1 set
NMR structure of the N-domain of troponin C bound to the switch region of troponin I and the covalent levosimendan analog i9. Troponin C with covalently bound levosimendan analog i9 enhances contraction in cardiac muscle fibers Download bibtex for citation iamge Brian D Sykes, Ian M Robertson, Malcolm Irving, Sandra E Pineda Sanabria, Yin-Biao Sun
25511 2016-06-30 Chemical Shifts: 1 set
T1 Relaxation Values: 2 sets
T2 Relaxation Values: 2 sets
Structure and dynamics of the acidosis-resistant a162H mutant of the switch region of troponin I bound to the regulatory domain of troponin C Structure and Dynamics of the Acidosis-Resistant A162H Mutant of the Switch Region of Troponin I Bound to the Regulatory Domain of Troponin C Download bibtex for citation iamge Brian D Sykes, Ian M Robertson, Sandra E Pineda Sanabria
25495 2015-06-01 Chemical Shifts: 1 set
Structure and dynamics of the acidosis-resistant a162H mutant of the switch region of troponin I bound to the regulatory domain of troponin C Structure and dynamics of the acidosis-resistant A162H mutant of the switch region of troponin I bound to the regulatory domain of troponin C Download bibtex for citation iamge Brian D Sykes, Ian M Robertson, Sandra E Pineda Sanabria
25034 2014-09-18 Chemical Shifts: 1 set
Heteronuclear NOE Values: 2 sets
T1 Relaxation Values: 2 sets
T2 Relaxation Values: 2 sets
Amide 1H and 15N chemical shift assignments and 15N relaxation parameters of the troponin C-troponin I hybrid proteins cChimera Versatile cardiac troponin chimera for muscle protein structural biology and drug discovery. Download bibtex for citation iamge Brian D Sykes, Olivier Julien, Sandra E Pineda-Sanabria
25035 2014-09-18 Chemical Shifts: 1 set
Heteronuclear NOE Values: 2 sets
T1 Relaxation Values: 2 sets
T2 Relaxation Values: 2 sets
Amide 1H and 15N chemical shift assignments and 15N relaxation parameters of the troponin C-troponin I hybrid proteins cChimeraX Versatile cardiac troponin chimera for muscle protein structural biology and drug discovery. Download bibtex for citation iamge Brian D Sykes, Olivier Julien, Sandra E Pineda-Sanabria
19817 2014-03-10 Chemical Shifts: 1 set
NMR structure of the dilated cardiomyopathy mutation G159D in troponin C bound to the anchoring region of troponin I The dilated cardiomyopathy G159D mutation in cardiac troponin C weakens the anchoring interaction with troponin I. Download bibtex for citation iamge Brian D Sykes, Ian M Robertson, Olga K Baryshnikova, Pascal Mercier
19816 2014-03-10 Chemical Shifts: 1 set
NMR structure of the C-domain of troponin C bound to the anchoring region of troponin I The dilated cardiomyopathy G159D mutation in cardiac troponin C weakens the anchoring interaction with troponin I. Download bibtex for citation iamge Brian D Sykes, Ian M Robertson, Olga K Baryshnikova, Pascal Mercier
19789 2014-02-11 Chemical Shifts: 2 sets
N domain of cardiac troponin C bound to the switch fragment of fast skeletal troponin I at pH 6 Conformation of the critical pH sensitive region of troponin depends upon a single residue in troponin I. Download bibtex for citation iamge Brian D Sykes, Ian M Robertson, Peter C Holmes, Sandra E Pineda-Sanabria
19484 2014-06-30 Chemical Shifts: 1 set
NMR structure of a two-transmembrane segment TM VI-VII of NHE1 Structural and Functional Analysis of the Transmembrane Segment Pair VI and VII of the NHE1 Isoform of the Na(+)/H(+) Exchanger Download bibtex for citation iamge Brian D Sykes, Brian L Lee, Claudia Alves, Larry Fliegel
19216 2013-06-04 Chemical Shifts: 1 set
Structural and Functional Analysis of Transmembrane Segment IV of the Salt Tolerance Protein Sod2 Structural and Functional Analysis of Transmembrane Segment IV of the Salt Tolerance Protein Sod2. Download bibtex for citation iamge Asad Ullah, Brian D Sykes, Brian Lee, Claudia Alves, Grant Kemp, Howard Young, Larry Fliegel
17440 2011-02-24 Chemical Shifts: 1 set
Structure of trans-Resveratrol in complex with the cardiac regulatory protein Troponin C Structure of trans-Resveratrol in Complex with the Cardiac Regulatory Protein Troponin C. Download bibtex for citation iamge Brian D Sykes, Ian M Robertson, Sandra E Pineda-Sanabria
17422 2011-02-09 Chemical Shifts: 1 set
Solution Structure of a DNA Duplex Containing the Potent Anti-Poxvirus Agent Cidofovir Solution structure of a DNA duplex containing the potent anti-poxvirus agent cidofovir. Download bibtex for citation iamge Brian D Sykes, David H Evans, James R Beadle, Karl Y Hostetler, Olivier Julien, Subhrangsu Chatterjee, Wendy C Magee
17423 2011-02-09 Chemical Shifts: 1 set
Solution Structure of a DNA Duplex Containing the Potent Anti-Poxvirus Agent Cidofovir Solution structure of a DNA duplex containing the potent anti-poxvirus agent cidofovir. Download bibtex for citation iamge Brian D Sykes, David H Evans, James R Beadle, Karl Y Hostetler, Olivier Julien, Subhrangsu Chatterjee, Wendy C Magee
17243 2011-06-01 Chemical Shifts: 1 set
The Solution Structure of Human Cardiac Troponin C in complex with the Green Tea Polyphenol; (-)-epigallocatechin-3-gallate Solution structure of human cardiac troponin C in complex with the green tea polyphenol, (-)-epigallocatechin 3-gallate. Download bibtex for citation iamge Brian D Sykes, Ian M Robertson, Monica X Li
17103 2010-09-08 Chemical Shifts: 1 set
The structure of the calcium-sensitizer, dfbp-o, in complex with the N-domain of troponin C and the switch region of troponin I A structural and functional perspective into the mechanism of Ca(2+)-sensitizers that target the cardiac troponin complex. Download bibtex for citation iamge Brian D Sykes, Ian M Robertson, Monica X Li, Yin-Biao Sun
17040 2010-09-03 Chemical Shifts: 1 set
STRUCTURAL AND FUNCTIONAL ANALYSIS OF TM VI OF THE NHE1 ISOFORM OF THE Na+/H+ EXCHANGER Structural and Functional Analysis of Transmembrane Segment VI of the NHE1 Isoform of the Na+/H+ Exchanger. Download bibtex for citation iamge Brian D Sykes, Brian L Lee, Jennifer Tzeng, Larry Fliegel
16752 2010-03-24 Binding_constants: 1 set
Mapping the Interacting Regions between Troponins T and C Mapping the Interacting Regions between Troponins T and C Download bibtex for citation iamge Brian D Sykes, Brian P Tripet, Robert S Hodges, Tharin MA Blumenschein
16414 2010-03-05 Binding_constants: 1 set
Interaction of the Second Binding Region Troponin I with the Regulatory Domain of Skeletal Muscle Troponin C as Determined by NMR Spectroscopy Interaction of the Second Binding Region of Troponin I with the Regulatory Domain of Skeletal Muscle Troponin C as Determined by NMR Spectroscopy Download bibtex for citation iamge Brian D Sykes, Brian P Tripet, Robert S Hodges, Ryan T McKay
16190 2009-05-20 Chemical Shifts: 1 set
Structure of the N-terminal domain of human cardiac troponin C bound to calcium ion and to the inhibitor W7 Structure of the inhibitor w7 bound to the regulatory domain of cardiac troponin C Download bibtex for citation iamge Brian D Sykes, Ryan MB Hoffman
16056 2009-01-21 Chemical Shifts: 1 set
STRUCTURAL AND FUNCTIONAL ANALYSIS OF TM XI OF THE NHE1 ISOFORM OF THE NA+/H+ EXCHANGER Structural and Functional Analysis of TM XI of the NHE1 Isoform of the Na+/H+ Exchanger Download bibtex for citation iamge Brian D Sykes, Brian L Lee, Larry Fliegel, Xiuju Li, Yongsheng Liu
15747 2008-05-29 Chemical Shifts: 1 set
Structural and Functional Characterization of TM IX of the NHE1 Isoform of the Na+/H+ Exchanger Structural and Functional Characterization of TM IX of the NHE1 Isoform of the Na+/H+ Exchanger Download bibtex for citation iamge Brian D Sykes, Jan K Rainey, J Ding, Larry Fliegel, Tyler Reddy, X Li
7245 2006-08-12 Chemical Shifts: 1 set
Structural and Functional Characterization of TM VII of the NHE1 Isoform of the Na+/H+ Exchanger Structural and functional characterization of transmembrane segment VII of the Na+/H+ exchanger isoform 1. Download bibtex for citation iamge Brian D Sykes, Carolyn Xu, Jan K Rainey, Jie Ding, Larry Fliegel
6260 2004-07-26 Chemical Shifts: 2 sets
NMR solution Structure of a Highly Stable de novo Heterodimeric Coiled-Coil NMR solution Structure of a Highly Stable de novo Heterodimeric Coiled-Coil Download bibtex for citation iamge Brian D Sykes, Darrin A Lindhout, Jennifer R Litowski, Pascal Mercier, Robert S Hodges
5975 2003-12-08 Chemical Shifts: 2 sets
1H and 15N chemical shift assignments for the N-domain of trout cardiac troponin C at 30 and 7 C Effect of temperature and the F27W mutation on the Ca2+ activated structural transition of trout cardiac troponin C Download bibtex for citation iamge Brian D Sykes, Glen F Tibbits, Tharin M A Blumenschein, Todd E Gillis
5572 2002-12-27 Chemical Shifts: 1 set
Beta-helix structure and ice-binding properties of a hyperactive antifreeze protein from an insect Beta-helix structure and ice-binding properties of a hyperactive antifreeze protein from an insect Download bibtex for citation iamge Brian D Sykes, Michael J Kuiper, Peter L Davies, Steffen P Graether, Stephane M Gagne, Virginia K Walker, Zongchao Jia
5573 2003-05-14 Chemical Shifts: 1 set
Spruce budworm Antifreeze Protein: Changes in Structure and Dynamics at Low Temperature Spruce Budworm Antifreeze Protein: Changes in Structure and Dynamics at Low Temperature Download bibtex for citation iamge Brian D Sykes, Leo Spyracopoulos, Peter L Davies, Steffen P Graether, Stephane M Gagne, Zongchao Jia
5386 2003-02-25 Chemical Shifts: 2 sets
Coupling Constants: 1 set
1H, 13C, 15N Chemical Shift Assignments of cNTnC and cTnI(147-163) in the cNTnC-cTnI(147-163)-Bepridil Ternary complex Structure of the Regulatory N-domain of Human Cardiac Troponin C in Complex with Human Cardiac Troponin I147-163 and Bepridil Download bibtex for citation iamge Brian D Sykes, Monica X Li, Xu Wang
5383 2003-01-06 Chemical Shifts: 1 set
The CXCR3 binding chemokine IP-10/CXCL10: Structure and receptor interactions The CXCR3 Binding Chemokine IP-10/CXCL10: Structure and Receptor Interactions Download bibtex for citation iamge Brian D Sykes, David W Keizer, Ian Clark-Lewis, Monique B Kamphuis, Valerie Booth
4994 2010-01-06 Chemical Shifts: 2 sets
Coupling Constants: 1 set
Structure of the C-domain of Human Cardiac Troponin C in Complex with the Ca2+ Sensitizing Drug EMD 57033 Structure of the C-domain of Human Cardiac Troponin C in Complex with the Ca2+ Sensitizing drug EMD 57033 Download bibtex for citation iamge Brian D Sykes, Leo Spyracopoulos, Monica X Li, Murali Chandra, Norbert Beier, R John Solaro, Xu Wang
4914 2001-01-23 Chemical Shifts: 1 set
Backbone 1H chemical shift assignments for vMIP-II Structure/Function of Human Herpesvirus-8 MIP-II (1-71) and the Antagonist N-terminal Segment (1-10) Download bibtex for citation iamge Brian D Sykes, Elena Elisseeva, Ian Clark-Lewis, Jiang-Hong Gong, Matthew P Crump
4918 2001-01-04 Chemical Shifts: 1 set
Coupling Constants: 1 set
Letter to the Editor: Assignments of 1H and 15N resonances of the Pseudomonas aeruginosa K122-4 pilin monomer. Letter to the Editor: Assignments of 1H and 15N resonances of the Pseudomonas aeruginosa K122-4 pilin monomer Download bibtex for citation iamge Brian D Sykes, David W Keizer, Jeong-Yong Suh, Matthew P Crump, Michal Kalsiak, Randall T Irvin
4836 2003-01-13 Chemical Shifts: 1 set
Complete 1H, 13C and 15N Backbone Assignments for the Hepatitis A Virus 3C Protease Letter to the Editor: Complete 1H, 13C and 15N backbone assignments for the hepatitis A virus 3C protease Download bibtex for citation iamge Brian D Sykes, Carolyn M Slupsky, David S Wishart, Leo Spyracopoulos, M Scott Watson, Trent C Bjorndahl
4686 2000-06-16 Chemical Shifts: 1 set
Coupling Constants: 1 set
The Human CC Chemokine I-309, Structural Consequences of the Additional Disulfide Bond. Human CC Chemokine I-309, Structural Consequences of the Additional Disulfide Bond. Download bibtex for citation iamge Brian D Sykes, Carolyn M Slupsky, David W Keizer, Ian Clark-Lewis, Matthew P Crump, Tae Woo Lee
4232 1999-05-25 Chemical Shifts: 2 sets
Coupling Constants: 1 set
N-Domain of Troponin C from Chicken Skeletal Muscle. Low Temperature-Induced Structural Changes in the Apo Regulatory Domain of Skeletal Muscle Troponin C Download bibtex for citation iamge A Miura, Brian D Sykes, L Spyracopoulos, Sakae Tsuda, S M Gagne
4080 2001-02-17 Chemical Shifts: 1 set
NMR Solution Structure of Calcium-Saturated Skeletal Muscle Troponin C NMR Solution Structure of Calcium-Saturated Skeletal Muscle Troponin C Download bibtex for citation iamge Brian D Sykes, Carolyn M Slupsky
290 1999-06-14 Chemical Shifts: 1 set
A 1H NMR Determination of the Solution Conformation of a Synthetic Peptide Analogue of Calcium-Binding Site III of Rabbit Skeletal Troponin C A 1H NMR Determination of the Solution Conformation of a Synthetic Peptide Analogue of Calcium-Binding Site III of Rabbit Skeletal Troponin C Download bibtex for citation iamge Brian D Sykes, Brian J Marsden, Robert S Hodges
862 1995-07-31 Chemical Shifts: 1 set
Hydrogen-1 Nuclear Magnetic Resonance Investigation of Bovine Cardiac Troponin C. Comparison of Tyrosyl Assignments and Calcium-Induced Structural Changes to Those of Two Homologous Proteins, Rabbit Skeletal Troponin C and Bovine Brain Calm Hydrogen-1 Nuclear Magnetic Resonance Investigation of Bovine Cardiac Troponin C. Comparison of Tyrosyl Assignments and Calcium-Induced Structural Changes to Those of Two Homologous Proteins, Rabbit Skeletal Troponin C and Bovine Brain Calm Download bibtex for citation iamge Brian D Sykes, Cyril M Kay, Maxwell T Hincke
2116 1999-06-14 Chemical Shifts: 1 set
Interaction of Troponin I and Troponin C (Use of the Two-dimensional Nuclear Magnetic Resonance Transferred Nuclear Overhauser Effect to Determine the Structure of the Inhibitory Troponin I Peptide when Bound to Skeletal Troponin C) Interaction of Troponin I and Troponin C (Use of the Two-dimensional Nuclear Magnetic Resonance Transferred Nuclear Overhauser Effect to Determine the Structure of the Inhibitory Troponin I Peptide when Bound to Skeletal Troponin C) Download bibtex for citation iamge A Patricia Campbell, Brian D Sykes
1039 1995-07-31 Chemical Shifts: 1 set
Complete Tyrosine Assignments in the High Field 1H Nuclear Magnetic Resonance Spectrum of the Bovine Pancreatic Trypsin Inhibitor Complete Tyrosine Assignments in the High Field 1H Nuclear Magnetic Resonance Spectrum of the Bovine Pancreatic Trypsin Inhibitor Download bibtex for citation iamge Brian D Sykes, Grayson H Snyder, Robert III, Susan Karplus
1228 1999-06-14 Chemical Shifts: 1 set
Nuclear Magnetic Resonance Studied of a Ca2+-Binding Fragment of Troponin C. Nuclear Magnetic Resonance Studied of a Ca2+-Binding Fragment of Troponin C. Download bibtex for citation iamge Brian D Sykes, Edward R Birnbaum
2763 1999-06-14 Chemical Shifts: 1 set
Comparison of the Structure and Dynamics of Chicken Gizzard and Rabbit Cardiac Tropomyosins: 1H NMR Spectroscopy and Measurement of Amide Hydrogen Exchange Rates Comparison of the Structure and Dynamics of Chicken Gizzard and Rabbit Cardiac Tropomyosins: 1H NMR Spectroscopy and Measurement of Amide Hydrogen Exchange Rates Download bibtex for citation iamge Brian D Sykes, Clive Sanders, Lawrence B Smillie
1227 1999-06-14 Chemical Shifts: 1 set
Nuclear Magnetic Resonance Studied of a Ca2+-Binding Fragment of Troponin C. Nuclear Magnetic Resonance Studied of a Ca2+-Binding Fragment of Troponin C. Download bibtex for citation iamge Brian D Sykes, Edward R Birnbaum
3119 1999-06-14 Chemical Shifts: 1 set
Stoichiometry of Calcium Binding to a Synthetic Heterodimeric Troponin-C Domain Stoichiometry of Calcium Binding to a Synthetic Heterodimeric Troponin-C Domain Download bibtex for citation iamge Brian D Sykes, Gary S Shaw, Robert S Hodges
3036 1999-06-14 Chemical Shifts: 1 set
Effect of Trifluoroethanol on Protein Secondary Structure: An NMR and CD Study Using a Synthetic Actin Peptide Effect of Trifluoroethanol on Protein Secondary Structure: An NMR and CD Study Using a Synthetic Actin Peptide Download bibtex for citation iamge Brian D Sykes, F D Sonnichsen, Jennifer Van Eyk, Robert S Hodges
1222 1999-06-14 Chemical Shifts: 1 set
Laser Photochemically Induced Dynamic Nuclear Polarization Proton Nuclear Magnetic Resonance Studies on Three Homologous Calcium Binding Proteins: Cardiac Troponin-C, Skeletal Troponin-C, and Calmodulin Laser Photochemically Induced Dynamic Nuclear Polarization Proton Nuclear Magnetic Resonance Studies on Three Homologous Calcium Binding Proteins: Cardiac Troponin-C, Skeletal Troponin-C, and Calmodulin Download bibtex for citation iamge Brian D Sykes, Cyril M Kay, Maxwell T Hincke
3118 1995-07-31 Chemical Shifts: 1 set
Stoichiometry of Calcium Binding to a Synthetic Heterodimeric Troponin-C Domain Stoichiometry of Calcium Binding to a Synthetic Heterodimeric Troponin-C Domain Download bibtex for citation iamge Brian D Sykes, Gary S Shaw, Robert S Hodges
3127 1999-06-14 Chemical Shifts: 1 set
Proton Nuclear Magnetic Resonance Studies of Porcine Intestinal Calcium Binding Protein Proton Nuclear Magnetic Resonance Studies of Porcine Intestinal Calcium Binding Protein Download bibtex for citation iamge Brian D Sykes, Joe DJ O'Neil, Judith G Shelling, Theo Hofmann
3128 1999-06-14 Chemical Shifts: 1 set
Proton Nuclear Magnetic Resonance Studies of Porcine Intestinal Calcium Binding Protein Proton Nuclear Magnetic Resonance Studies of Porcine Intestinal Calcium Binding Protein Download bibtex for citation iamge Brian D Sykes, Joe DJ O'Neil, Judith G Shelling, Theo Hofmann
3404 2008-03-24 Chemical Shifts: 1 set
A Single-Stranded Amphiphatic alpha-Helix in Aqueous Solution: Design, Structural Characterization, and Its Application for Determining alpha-Helical Propensities of Amino Acids A Single-Stranded Amphiphatic alpha-Helix in Aqueous Solution: Design, Structural Characterization, and Its Application for Determining alpha-Helical Propensities of Amino Acids Download bibtex for citation iamge Brian D Sykes, Cyril M Kay, Nian E Zhou, Robert S Hodges
846 1995-07-31 Chemical Shifts: 1 set
Hydrogen-1 Nuclear Magnetic Resonance Investigation of Bovine Cardiac Troponin C. Comparison of Tyrosyl Assignments and Calcium-Induced Structural Changes to Those of Two Homologous Proteins, Rabbit Skeletal Troponin C and Bovine Brain Calm Hydrogen-1 Nuclear Magnetic Resonance Investigation of Bovine Cardiac Troponin C. Comparison of Tyrosyl Assignments and Calcium-Induced Structural Changes to Those of Two Homologous Proteins, Rabbit Skeletal Troponin C and Bovine Brain Calm Download bibtex for citation iamge Brian D Sykes, Cyril M Kay, Maxwell T Hincke
2117 1999-06-14 Chemical Shifts: 1 set
Interaction of Troponin I and Troponin C (Use of the Two-dimensional Nuclear Magnetic Resonance Transferred Nuclear Overhauser Effect to Determine the Structure of the Inhibitory Troponin I Peptide when Bound to Skeletal Troponin C) Interaction of Troponin I and Troponin C (Use of the Two-dimensional Nuclear Magnetic Resonance Transferred Nuclear Overhauser Effect to Determine the Structure of the Inhibitory Troponin I Peptide when Bound to Skeletal Troponin C) Download bibtex for citation iamge A Patricia Campbell, Brian D Sykes