BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

Summary of BMRB entries for NMR studies on biomolecules related to SARS-CoV-2 NSPs.

Note all structures currently available for SARS-CoV-2 non-structural proteins (last column) are from X-ray diffraction. BMRB and PDB accession codes are hyperlinked to their respective entries. Titles are hyperlinked to the PubMed entry for the relevant publication.

You can sort any column by clicking on the column header.

Entry ID Description Protein/nucleic acid Protein/Domain PDB entry SARS-CoV2 homolog % Identity with SARS-CoV2 SARS-CoV2 structures
50352 Assignment of base 15N and 1H chemical shifts for 5_SL8 RNA
50351 Assignment of base 15N, 13C and 1H chemical shifts for 5_SL6 RNA
50350 Assignment of base 15N and 1H chemical shifts for 3_SL3base RNA
50349 Assignment of base 15N and 1H chemical shifts for <5_SL1> RNA
50348 Assignment of base imino 1H and 15N chemical shifts for PK RNA
50347 Assignment of anomeric protons and base 1H, 13C and 15N chemical shifts for 5_SL4 RNA
50346 Assignment of anomeric protons and base 1H, 13C and 15N chemical shifts for 5_SL4 RNA
50344 Assignment of base 1H and 15N chemical shifts for 5_SL2+3 RNA
50343 Assignment of base 1H and 15N chemical shifts for 3_SL3 RNA
50342 Assignment of base 1H and 15N chemical shifts for 3_SL1 RNA
50341 Assignment of base 15N and 1H chemical shifts for <3_s2m> RNA
50340 Assignment of base 15N and 1H chemical shifts for 5_SL5stem RNA
50339 Assignment of base 15N and 1H chemical shifts for <5_SL5B+C> RNA
50262 Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virusreplication Protein Nsp5/MPro 6WTK, 6WTM, 6WTJ Nsp5 100 6Y2E
34511 The N-terminal RNA-binding domain of the SARS-CoV-2 nucleocapsid phosphoprotein Protein N/NTD 6YI3 N/NTD 100 6YI3
36080 NMR structure and localization of a large fragment of the SARS-CoV fusion protein: Implications in viral cell fusion Protein S/S2 5XJK S 83 6VYB, 6VXX
36074 Structural insights of a self-assembling 9-residue peptide from the C-terminal tail of the SARS corona virus E-protein in DPC and SDS micelles: A combined high and low resolution spectroscopic study Protein E/C-term. 9 aa 5XES E 100
36073 Structural insights of a self-assembling 9-residue peptide from the C-terminal tail of the SARS corona virus E-protein in DPC and SDS micelles: A combined high and low resolution spectroscopic study Protein E/C-term. 9 a 5XER E 100
36049 Structure of the SARS coronavirus E protein pentameric ion channel in LMPG micelles Protein E 5X29 E 89
30531 Structure of the SARS-Unique Domain C from the Bat Coronavirus HKU4 Protein Nsp3/SUD-C 6MWM Nsp3/SUD-C 39
30247 SARS-Unique Fold in the Rousettus Bat Coronavirus HKU9 Protein Nsp3/SUD-C 5UTV Nsp3/SUD-C 57
27177 Comprehensive structural analysis of designed incomplete polypeptide chains of the replicase nonstructural protein 1 from the severe acute respiratory syndrome coronavirus Protein Nsp1/13-50 aa Nsp1 95
27176 Comprehensive structural analysis of designed incomplete polypeptide chains of the replicase nonstructural protein 1 from the severe acute respiratory syndrome coronavirus Protein Nsp1/13-25 aa Nsp1 100
27169 Comprehensive structural analysis of designed incomplete polypeptide chains of the replicase nonstructural protein 1 from the severe acute respiratory syndrome coronavirus Protein Nsp1/GB1 Nsp1 33
26657 NMR assignments of the macro domain from Middle East respiratory syndrome coronavirus (MERS-CoV) Protein Nsp3/ADPR Nsp3/ADPR 44 6W6Y, 6W02
19845 Structure of a Conserved Golgi Complex-targeting Signal in Coronavirus Envelope Proteins. Protein E 2MM4 E 91
17911 NMR solution structure of C-terminal domain of SARS-CoV main protease in 2.5M urea Protein Nsp5/MPro-C 2LIZ Nsp5 97 6W63, 6Y84
17309 The solution structure of coronaviral stem-loop 2 (SL2) reveals a canonical CUYG tetraloop fold. RNA 2L6I
17251 1H, 13C and 15N resonance assignments of SARS-CoV main protease N-terminal domain. Protein Nsp5/MPro-N Nsp5 96 6W63, 6Y84
17217 Solution Structure of the C-terminal Dimerization Domain of SARS Coronavirus Nucleocapsid Protein Solved by the SAIL-NMR Method Protein N/CTD 2JW8 N 96
15511 Solution Structure of the C-terminal Dimerization Domain of SARS Coronavirus Nucleocapsid Protein Solved by the SAIL-NMR Method Protein N/CTD 2JW8 N 96
16981 NMR Structure of the SARS-CoV Nonstructural Protein 7 in Solution at pH6.5. Protein Nsp7 2KYS Nsp7 99
16613 SARS coronavirus unique domain: three-domain molecular architecture in solution and RNA binding. Protein Nsp3/SUD-MC 2KQV, 2KQW Nsp3 79
16008 Nuclear magnetic resonance structure of the nucleic acid-binding domain of severe acute respiratory syndrome coronavirus nonstructural protein 3. Protein Nsp3/SUD-MC 2KAF Nsp3 76
15723 NMR assignment of the nonstructural protein nsp3(1066-1181) from SARS-CoV Protein Nsp3/NAB (nsp3e) 2K87 Nsp3 82
15618 Nuclear magnetic resonance structure shows that the severe acute respiratory syndrome coronavirus-unique domain contains a macrodomain fold Protein Nsp3/SUD-M 2JZD Nsp3 81
15469 NMR assignment of the domain 513-651 from the SARS-CoV nonstructural protein nsp3 Protein Nsp3/SUD-M Nsp3 80
11582 NMR Structures and Localization of Potential Fusion Peptides and Pre-transmembrane Region of SARS-CoV: Implications in Membrane Fusion Protein S 2RUO S 100 6VYB, 6VXX
11581 NMR Structures and Localization of Potential Fusion Peptides and Pre-transmembrane Region of SARS-CoV: Implications in Membrane Fusion Protein S 2RUN S 94 6VYB, 6VXX
11580 NMR Structures and Localization of Potential Fusion Peptides and Pre-transmembrane Region of SARS-CoV: Implications in Membrane Fusion Protein S 2RUM S 74 6VYB, 6VXX
7019 NMR assignment of the protein nsp3a from SARS-CoV Protein Nsp3/UB1 (nsp3a) 2GRI Nsp3 79
7014 NMR assignment of the SARS-CoV protein nsp1 Protein Nsp1 2GRI Nsp1 79
6969 Solution structure of the SARS-coronavirus HR2 domain in the prefusion state Protein S 2GRI S 98 6VYB, 6VXX
6824 Solution structure of the X4 protein coded by the SARS related coronavirus reveals an immunoglobulin like fold and suggests a binding activity to integrin I domains. Protein ORF7a (X4, U122) 1YO4 ORF7a
6513 Structural genomics of the SARS coronavirus: NMR structure of the protein nsp7 Protein Nsp7 1YSY Nsp7 99
6501 Backbone dynamics of SARS-CoV Nsp9 by NMR spectroscopy Protein Nsp9 Nsp9 97
6372 Letter to the Editor: 1H, 13C and 15N resonance assignments of the N-terminal Domain of the SARS CoV Nucleocapsid Protein Protein N/NTD N 90 6M3M

NMR data on relevant small molecules

Chlorohydroquinone

Colchicine

Others