BMRB Entry 6612

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PDB ID: 1z1m
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR6612
MolProbity Validation Chart

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Title:
NMR structure of unliagnded MDM2
Deposition date:
2005-04-28
Original release date:
2005-10-27
Authors:
Uhrinova, S.; Uhrin, D.; Powers, H.; Watt, K.; Zheleva, D.; Fischer, P.; McInnes, C.; Barlow, P.
Citation:

Citation: Uhrinova, S.; Uhrin, D.; Powers, H.; Watt, K.; Zheleva, D.; Fischer, P.; McInnes, C.; Barlow, P.. "Structure of free MDM2 N-terminal domain reveals conformational adjustments that accompany p53-binding."  J. Mol. Biol. 350, 587-598 (2005).
PubMed: 15953616

Assembly members:

Assembly members:
Ubiquitin-protein ligase E3 Mdm2 (E.C.6.3.2.-), polymer, 119 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology

Entity Sequences (FASTA):

Entity Sequences (FASTA):
Ubiquitin-protein ligase E3 Mdm2 (E.C.6.3.2.-): MCNTNMSVPTDGAVTTSQIP ASEQETLVRPKPLLLKLLKS VGAQKDTYTMKEVLFYLGQY IMTKRLYDEKQQHIVYCSND LLGDLFGVPSFSVKEHRKIY TMIYRNLVVVNQQESSDSS

Data sets:
Data typeCount
1H chemical shifts719
13C chemical shifts320
15N chemical shifts103

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
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Assembly:

Entity Assembly IDEntity NameEntity ID
1Ubiquitin-protein ligase E3 Mdm21

Entities:

Entity 1, Ubiquitin-protein ligase E3 Mdm2 119 residues - Formula weight is not available

1   METCYSASNTHRASNMETSERVALPROTHR
2   ASPGLYALAVALTHRTHRSERGLNILEPRO
3   ALASERGLUGLNGLUTHRLEUVALARGPRO
4   LYSPROLEULEULEULYSLEULEULYSSER
5   VALGLYALAGLNLYSASPTHRTYRTHRMET
6   LYSGLUVALLEUPHETYRLEUGLYGLNTYR
7   ILEMETTHRLYSARGLEUTYRASPGLULYS
8   GLNGLNHISILEVALTYRCYSSERASNASP
9   LEULEUGLYASPLEUPHEGLYVALPROSER
10   PHESERVALLYSGLUHISARGLYSILETYR
11   THRMETILETYRARGASNLEUVALVALVAL
12   ASNGLNGLNGLUSERSERASPSERSER

Related Database Links:

BMRB 18755 19230 2410
PDB 1RV1 1T4E 1T4F 1YCR 1Z1M 2AXI 2GV2 2LZG 2M86 2RUH 3EQS 3G03 3IUX 3IWY 3JZK 3JZR 3JZS 3LBK 3LBL 3LNJ 3LNZ 3TJ2 3TPX 3TU1 3V3B 3VBG 3VZV 3W69 4DIJ 4ERE 4ERF 4HBM 4HFZ 4JV7 4JV9 4JVE 4JVR 4JWR 4MDN 4MDQ 4OAS 4OBA 4OCC 4ODE 4ODF 4OGN 4OGT 4OGV 4OQ3 4QO4 4UMN 4WT2
DBJ BAF83030 BAJ17752
EMBL CAA78055 CAD23251 CAD36959 CAD79457 CAH89564
GB AAA60568 AAI48523 AAI52385 AAI52391 AAI53118
PRF 1814460A
REF NP_001124685 NP_001138809 NP_001138811 NP_001253331 NP_002383
SP Q00987
AlphaFold Q00987

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks