BMRB Entry 19739

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PDB ID: 2mjw
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full, LACS, SPARTA
BMRB Entry DOI: doi:10.13018/BMR19739
MolProbity Validation Chart

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Title:
Structural Insights into Calcium Bound S100P - V Domain of the receptor for advanced glycation end products (RAGE) Complex
Deposition date:
2014-01-19
Original release date:
2014-11-03
Authors:
Penumutchu, Srinivasa
Citation:

Citation: Penumutchu, Srinivasa; Chou, Ruey-Hwang; Yu, Chin. "Structural insights into calcium-bound S100P and the V domain of the RAGE complex"  PLoS One 9, e103947-e103947 (2014).
PubMed: 25084534

Assembly members:

Assembly members:
entity_1, polymer, 101 residues, 11217.104 Da.
entity_2, polymer, 188 residues, 20547.553 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET-15b(+)

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: AMAQNITARIGEPLVLKCKG APKKPPQRLEWKLNTGRTEA WKVLSPQGGGPWDSVARVLP NGSLFLPAVGIQDEGIFRCQ AMNRNGKETKSNYRVRVYQI P
entity_2: MTELETAMGMIIDVFSRYSG SEGSTQTLTKGELKVLMEKE LPGFLQSGKDKDAVDKLLKD LDANGDAQVDFSEFIVFVAA ITSACHKYFEKAGLMTELET AMGMIIDVFSRYSGSEGSTQ TLTKGELKVLMEKELPGFLQ SGKDKDAVDKLLKDLDANGD AQVDFSEFIVFVAAITSACH KYFEKAGL

Data sets:
Data typeCount
13C chemical shifts214
15N chemical shifts81
1H chemical shifts443

Additional metadata:

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  • Samples and Experiments
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Assembly:

Entity Assembly IDEntity NameEntity ID
1V-domain of Rage_11
2V-domain of Rage_21
3Calcium Bound S100P2

Entities:

Entity 1, V-domain of Rage_1 101 residues - 11217.104 Da.

1   ALAMETALAGLNASNILETHRALAARGILE
2   GLYGLUPROLEUVALLEULYSCYSLYSGLY
3   ALAPROLYSLYSPROPROGLNARGLEUGLU
4   TRPLYSLEUASNTHRGLYARGTHRGLUALA
5   TRPLYSVALLEUSERPROGLNGLYGLYGLY
6   PROTRPASPSERVALALAARGVALLEUPRO
7   ASNGLYSERLEUPHELEUPROALAVALGLY
8   ILEGLNASPGLUGLYILEPHEARGCYSGLN
9   ALAMETASNARGASNGLYLYSGLUTHRLYS
10   SERASNTYRARGVALARGVALTYRGLNILE
11   PRO

Entity 2, Calcium Bound S100P 188 residues - 20547.553 Da.

1   METTHRGLULEUGLUTHRALAMETGLYMET
2   ILEILEASPVALPHESERARGTYRSERGLY
3   SERGLUGLYSERTHRGLNTHRLEUTHRLYS
4   GLYGLULEULYSVALLEUMETGLULYSGLU
5   LEUPROGLYPHELEUGLNSERGLYLYSASP
6   LYSASPALAVALASPLYSLEULEULYSASP
7   LEUASPALAASNGLYASPALAGLNVALASP
8   PHESERGLUPHEILEVALPHEVALALAALA
9   ILETHRSERALACYSHISLYSTYRPHEGLU
10   LYSALAGLYLEUMETTHRGLULEUGLUTHR
11   ALAMETGLYMETILEILEASPVALPHESER
12   ARGTYRSERGLYSERGLUGLYSERTHRGLN
13   THRLEUTHRLYSGLYGLULEULYSVALLEU
14   METGLULYSGLULEUPROGLYPHELEUGLN
15   SERGLYLYSASPLYSASPALAVALASPLYS
16   LEULEULYSASPLEUASPALAASNGLYASP
17   ALAGLNVALASPPHESERGLUPHEILEVAL
18   PHEVALALAALAILETHRSERALACYSHIS
19   LYSTYRPHEGLULYSALAGLYLEU

Related Database Links:

BMRB 17378 19953 17866
PDB 2E5E 2L7U 2M1K 2MJW 2MOV 3CJJ 3O3U 4LP4 4LP5 4OF5 4OFV 4OI7 4OI8 4P2Y 1J55
DBJ BAA05958 BAA89369 BAC65465 BAG35995 BAG60385 BAJ20330
GB AAA03574 AAB47491 AAH20669 AAX07272 AAX07273 AAH06819 AAO41114 AAP35953 AAX31997 AAX31998
REF NP_001127 NP_001192046 NP_001193858 NP_001193863 NP_001193865 NP_005971 XP_001091876 XP_002814597 XP_003310290 XP_003816512
SP Q15109 P25815
EMBL CAA46566
AlphaFold Q15109 P25815

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