Entry ID | Original Release date | Data summary | Entry Title | Citation Title | Authors |
---|---|---|---|---|---|
51999 | 2023-10-03 | Chemical Shifts: 1 set |
Methyl assignments of the light chain from the open MHC mutant HLA-B*37:01-G121C/b2m-H32C/FEDLRVJSF(photoB37) human MHC-I protein complex | A Chicken Tapasin ortholog can chaperone empty HLA-B*37:01 molecules independent of other peptide-loading components | Claire H Woodward, George M Burslem, Georgia F Papadaki, Michael C Young, Nikolaos G Sgourakis, Trenton J Winters |
51781 | 2023-06-15 | Chemical Shifts: 2 sets |
Backbone assignments of the heavy and light chains from the disulfide mutant HLA-A*02:01-G121C/b2m-H32C/ELAGIGILTV(MART-1) human MHC-I protein complex | Universal open MHC-I molecules for rapid peptide loading and enhanced complex stability across HLA allotypes | Claire H Woodward, George M Burslem, Hau V Truong, Joan Font-Burgada, Julia N Danon, Michael C Young, Nikolaos G Sgourakis, Sagar Gupta, Trenton J Winters, Yi Sun |
51101 | 2023-06-15 | Chemical Shifts: 2 sets |
Backbone assignments of the heavy and light chains from the HLA-A*02:01/b2m/ELAGIGILTV(MART-1) human MHC-I protein complex | Universal open MHC-I molecules for rapid peptide loading and enhanced complex stability across HLA allotypes | Claire H Woodward, George M Burslem, Hau V Truong, Joan Font-Burgada, Julia N Danon, Michael C Young, Nikolaos G Sgourakis, Sagar Gupta, Trenton J Winters, Yi Sun |
51100 | 2022-10-12 | Chemical Shifts: 1 set |
Methyl resonance assignments of beta-2 microglobulin in complex with HLA-B*44:05T73C/EEFGRC and tapasin | Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation | Claire H Woodward, Daniel K Taylor, David H Margulies, Ellen J Kim, Hau V Truong, Javeed Ahmad, Jiansheng Jiang, Kannan Natarajan, Lisa F Boyd, Michael G Mage, Nikolaos G Sgourakis, Peter Cresswell |
51099 | 2022-10-12 | Chemical Shifts: 1 set |
Methyl resonance assignments of beta-2 microglobulin in complex with HLA-B*44:05T73C/EEFGRC | Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation | Claire H Woodward, Daniel K Taylor, David H Margulies, Ellen J Kim, Hau V Truong, Javeed Ahmad, Jiansheng Jiang, Kannan Natarajan, Lisa F Boyd, Michael G Mage, Nikolaos G Sgourakis, Peter Cresswell |
51097 | 2022-10-12 | Chemical Shifts: 1 set Residual Dipolar Couplings: 1 set |
Resonance assignments and Residual Dipolar Couplings for Human Beta-2 microglobulin (b2m) | Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation | Claire H Woodward, Daniel K Taylor, David H Margulies, Ellen J Kim, Hau V Truong, Javeed Ahmad, Jiansheng Jiang, Kannan Natarajan, Lisa F Boyd, Michael G Mage, Nikolaos G Sgourakis, Peter Cresswell |
51098 | 2022-10-12 | Chemical Shifts: 1 set |
Backbone and methyl resonance assignments of beta-2 microglobulin in complex with HLA-B*44:05/EEFGRAFSF | Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation | Claire H Woodward, Daniel K Taylor, David H Margulies, Ellen J Kim, Hau V Truong, Javeed Ahmad, Jiansheng Jiang, Kannan Natarajan, Lisa F Boyd, Michael G Mage, Nikolaos G Sgourakis, Peter Cresswell |
51045 | 2021-08-30 | Chemical Shifts: 1 set |
AILV methyl assignments for beta 2 microglobulin bound to hpMR1 and Ac-6-FP | TAPBPR employs a ligand-independent docking mechanism to chaperone MR1 molecules | Adam I Green, Andrew C McShan, Christine A Devlin, Erik Procko, George M Burslem, Georgia F Papadaki, Giora I Morozov, Nikolaos G Sgourakis, Yi Sun |
51046 | 2021-08-30 | Chemical Shifts: 1 set |
AILV assignments of hpMR1 bound to bovien beta 2 microglobulin and Ac-6-FP | TAPBPR employs a ligand-independent docking mechanism to chaperone MR1 molecules | Adam I Green, Andrew C McShan, Christine A Devlin, Erik Procko, George M Burslem, Georgia F Papadaki, Giora I Morozov, Nikolaos G Sgourakis, Yi Sun |
51044 | 2021-08-30 | Chemical Shifts: 2 sets |
AILV methyl assignments of hpMR1 bound to Ac-6-FP, bB2m and TAPBPR | TAPBPR employs a ligand-independent docking mechanism to chaperone MR1 molecules | Adam I Green, Andrew C McShan, Christine A Devlin, Erik Procko, George M Burslem, Georgia F Papadaki, Giora I Morozov, Nikolaos G Sgourakis, Yi Sun |
28114 | 2020-05-15 | Chemical Shifts: 1 set |
AILVproS stereospecific methyl chemical shift assignments of HLA-A*01:01, a human class I major histocompatibility complex heavy chain, bound to NRASQ61K neoepitope and human beta-2 microglobulin | AILVproS stereospecific methyl chemical shift assignments of HLA-A*01:01, a human class I major histocompatibility complex heavy chain, bound to NRASQ61K neoepitope and human beta-2 microglobulin | Andrew C McShan, Nikolaos G Sgourakis |
28110 | 2020-12-02 | Chemical Shifts: 1 set |
Backbone and ILV methyl assignments for REC3 domain of SpCas9 | Backbone-independent NMR resonance assignments of methyl probes in large proteins | Andrew C McShan, Nikolaos G Sgourakis, Santrupti Nerli, Viviane S De Paula |
28108 | 2020-04-02 | Chemical Shifts: 1 set |
ILVproS methyl chemical shift assignments of HLA-A*02:01, a human major histocompatibility complex heavy chain, peptide-deficient and bound to human beta-2 microglobulin and the molecular chaperone TAPBPR | TAPBPR Promotes Loading of Cargo on MHC-I Molecules Using a Peptide Trap | Andrew C McShan, Christine A Devlin, Danai Moschidi, Erik Procko, Giora I Morozov, Neha Akella, Nikolaos G Sgourakis, Sarah A Overall |
28107 | 2020-04-02 | Chemical Shifts: 1 set |
ILVproS methyl chemical shift assignments of HLA-A*02:01, a human class I major histocompatibility complex heavy chain, bound to TAX9 and human beta-2 microglobulin | TAPBPR Promotes Loading of Cargo on MHC-I Molecules Using a Peptide Trap | Andrew C McShan, Christine A Devlin, Danai Moschidi, Erik Procko, Giora I Morozov, Neha Akella, Nikolaos G Sgourakis, Sarah A Overall |
28104 | 2020-12-02 | Chemical Shifts: 1 set |
Backbone and ILV methyl assignments of human Interleukin-2 | Backbone-independent NMR resonance assignments of methyl probes in large proteins | Andrew C McShan, Nikolaos G Sgourakis, Santrupti Nerli, Viviane S De Paula |
28105 | 2020-12-02 | Chemical Shifts: 1 set |
Backbone and ILV methyl chemical shift assignments of REC2 domain from SpyCas9 | Backbone-independent NMR resonance assignments of methyl probes in large proteins | Andrew C McShan, Nikolaos G Sgourakis, Santrupti Nerli, Viviane S De Paula |
28106 | 2020-12-02 | Chemical Shifts: 1 set |
Backbone and ILV methyl assignments for HNH domain of SpCas9 | Backbone-independent NMR resonance assignments of methyl probes in large proteins | Andrew C McShan, Nikolaos G Sgourakis, Santrupti Nerli, Viviane S De Paula |
27974 | 2020-04-03 | Chemical Shifts: 1 set |
MILV methyl chemical shift assignments of the R52A mutant of mouse Interleukin-2 | Interleukin-2 druggability is modulated by global conformational transitions controlled by a helical capping switch | Caleb R Glassman, K Christopher C Garcia, Kevin M Jude, Nikolaos G Sgourakis, Santrupti Nerli, Viviane S De Paula |
27971 | 2020-04-03 | Chemical Shifts: 1 set |
ILV(proS) methyl assignment of mIL-2 in complex with IL-2Ra (CD25) receptor | Interleukin-2 druggability is modulated by global conformational transitions controlled by a helical capping switch | Caleb R Glassman, K Christopher C Garcia, Kevin M Jude, Nikolaos G Sgourakis, Santrupti Nerli, Viviane S De Paula |
27970 | 2020-04-03 | Chemical Shifts: 1 set |
ILV(proS) methyl assignment of mIL-2 in complex with JES6-1 scFV antibody | Interleukin-2 druggability is modulated by global conformational transitions controlled by a helical capping switch | Caleb R Glassman, K Christopher C Garcia, Kevin M Jude, Nikolaos G Sgourakis, Santrupti Nerli, Viviane S De Paula |
27969 | 2020-04-03 | Chemical Shifts: 1 set |
Backbone amide and MILV methyl chemical shift assignments of mouse Interleukin-2 | Interleukin-2 druggability is modulated by global conformational transitions controlled by a helical capping switch | Caleb R Glassman, K Christopher C Garcia, Kevin M Jude, Nikolaos G Sgourakis, Santrupti Nerli, Viviane S De Paula |
27764 | 2019-06-13 | Chemical Shifts: 3 sets |
FoxM1 Transactivation Domain, Phosphorylated form | An order-to-disorder structural switch activates the FoxM1 transcription factor. | Aimee H Marceau, Andrew C McShane, Caileen Brison, Eefei Chen, Heather E Arsenault, Hsiau-Wei Lee, Jennifer A Benanti, Nikolaos G Sgourakis, Santrupti Nerli, Seth M Rubin |
27763 | 2019-06-13 | Chemical Shifts: 1 set |
FoxM1 Transactivation Domain | An order-to-disorder structural switch activates the FoxM1 transcription factor. | Aimee H Marceau, Andrew C McShane, Caileen Brison, Eefei Chen, Heather E Arsenault, Hsiau-Wei Lee, Jennifer A Benanti, Nikolaos G Sgourakis, Santrupti Nerli, Seth M Rubin |
27682 | 2020-02-28 | Chemical Shifts: 1 set |
Backbone amide and AILV methyl chemical shift assignments for H2-Ld, a mouse class I major histocompatibility molecule heavy chain | Molecular determinants of chaperone interactions on MHC-I for folding and antigen repertoire selection | Andrew C McShan, Christine A Devlin, Danai Moschidi, David Flores-Solis, Erik Procko, Hannah Choi, Jihye Park, Jugmohit S Toor, Nikolaos G Sgourakis, Sarah A Overall, Sarvind Tripathi |
27631 | 2018-11-01 | Chemical Shifts: 1 set |
Backbone amide and AILV methyl chemical shift assignments for HLA-A*02:01, a human class I major histocompatibility molecule heavy chain. | Molecular determinants of chaperone interactions on MHC-I for folding and antigen repertoire selection | Andrew C McShan, Christine A Devlin, Danai Moschidi, David Flores-Solis, Erik Procko, Hannah Choi, Jihye Park, Jugmohit S Toor, Nikolaos G Sgourakis, Sarah A Overall, Sarvind Tripathi |
27632 | 2018-11-01 | Chemical Shifts: 2 sets |
Backbone amide and AILV methyl chemical shift assignments for HLA-A*01:01, a human class I major histocompatibility molecule heavy chain | Molecular determinants of chaperone interactions on MHC-I for folding and antigen repertoire selection | Andrew C McShan, Christine A Devlin, Danai Moschidi, David Flores-Solis, Erik Procko, Hannah Choi, Jihye Park, Jugmohit S Toor, Nikolaos G Sgourakis, Sarah A Overall, Sarvind Tripathi |
30495 | 2018-10-31 | Chemical Shifts: 1 set |
Solution NMR structure of a de novo designed double-stranded beta-helix | De novo design of a non-local beta-sheet protein with high stability and accuracy. | Andrew C McShan, Audrey Davis, David Baker, Enrique Marcos, Gustav Oberdorfer, Konstantinos Tripsianes, Lauren Carter, Lucas G Nivon, Nikolaos G Sgourakis, Santrupti Nerli, Tamuka M Chidyausiku, Thomas Evangelidis |
30474 | 2018-12-13 | Chemical Shifts: 1 set Spectral_peak_list: 2 sets |
De Novo Design of a Protein Heterodimer with Specificity Mediated by Hydrogen Bond Networks | Programmable design of orthogonal protein heterodimers. | Aniruddha Sahasrabuddhe, David Baker, David Flores-Solis, Florian Busch, Frank DiMaio, Lauren P Carter, Matthew J Bick, Mengxuan Jia, Nikolaos G Sgourakis, Peilong Lu, Robert A Langan, Scott E Boyken, Sherry Bermeo, T J Brunette, Vicki H Wysocki, Vikram Khipple K Mulligan, Zachary L VanAernum, Zibo Chen |
27249 | 2018-08-16 | Chemical Shifts: 1 set |
Backbone amide and AILV methyl chemical shift assignments for H2-Dd, a murine class I major histocompatibility molecule heavy chain | Peptide exchange on MHC-I by TAPBPR is driven by a negative allostery release cycle | Andrew C McShan, Clive R Bagshaw, David Flores-Solis, David H Margulies, Evgenii L Kovrigin, Jiansheng Jiang, Jugmohit S Toor, Kannan Natarajan, Mareike Badstubner, Nikolaos G Sgourakis, Vlad K Kumirov |
27248 | 2018-08-16 | Chemical Shifts: 1 set |
Backbone amide and AILV methyl chemical shift assignments for Beta2-microglobulin, a human class I major histocompatibility molecule light chain | Peptide exchange on MHC-I by TAPBPR is driven by a negative allostery release cycle | Andrew C McShan, Clive R Bagshaw, David Flores-Solis, David H Margulies, Evgenii L Kovrigin, Jiansheng Jiang, Jugmohit S Toor, Kannan Natarajan, Mareike Badstubner, Nikolaos G Sgourakis, Vlad K Kumirov |
26977 | 2017-05-23 | Chemical Shifts: 1 set |
An allosteric site in the T cell receptor constant domain plays a critical role in T cell signaling | An allosteric site in the T-cell receptor Cbeta domain plays a critical signalling role | Ad Bax, Andrew C McShan, David H Margulies, Huaying Zhao, Jiansheng Jiang, Jinfa Ying, Kannan Natarajan, Lisa F Boyd, Mulualem E Tilahun, Nikolaos G Sgourakis, Peter Schuck, Rui Wang, Vlad K Kumirov |
26646 | 2016-07-15 | Chemical Shifts: 1 set |
A Novel MHC-I Surface Targeted for Binding by the MCMV m06 Immunoevasin Revealed by Solution NMR | A Novel MHC-I Surface Targeted for Binding by the MCMV m06 Immunoevasin Revealed by Solution NMR | Ad Bax, David H Margulies, Jinfa Ying, Lisa F Boyd, Nathan A May, Nikolaos G Sgourakis |
25237 | 2014-12-08 | Chemical Shifts: 1 set |
Solution NMR Structure of Maltose-binding protein from Escherichia coli, Northeast Structural Genomics Consortium (NESG) Target ER690 | Solution NMR Structure of Maltose-binding protein from Escherichia coli, Northeast Structural Genomics Consortium (NESG) Target ER690 | Asli Ertekin, David Baker, Gaetano T Montelione, Hsiau-Wei Lee, James M Aramini, Nikolaos G Sgourakis, Oliver F Lange, Paolo Rossi, Rong Xiao, Thomas B Acton, Yifan Song |
19699 | 2014-07-14 | Chemical Shifts: 1 set |
Structure of the m04/gp34 mouse Cytomegalovirus Immunoevasin core domain | The murine Cytomegalovirus gp34/m04 protein contains a core domain with novel structure revealed by solution NMR | Ad Bax, David H Margulies, Kannan Natarajan, Nikolaos G Sgourakis |
19235 | 2013-09-03 | Chemical Shifts: 1 set |
Solution structure of the Aha1 dimer from Colwellia psychrerythraea | Discriminating the Symmetric Dimer Interface of the 33kDa Aha1 Domain by combining NMR and SAXS data in a hybrid method | Christopher M Barbieri, David Baker, Edward H Snell, Gaetano T Montelione, Gaohua Liu, Hsiau-Wei Lee, Joseph R Luft, Lei Shi, Nikolaos G Sgourakis, Oliver A Lange, Paolo Rossi, Rong Xiao, Thomas B Acton, Thomas D Grant |
18651 | 2013-02-14 | Chemical Shifts: 1 set |
13C and 15N chemical shifts for Shigella Flexneri MxiH Type three secretion system needle subunit | The Common Structural Architecture of Shigella flexneri and Salmonella typhimurium Type Three Secretion Needles | Adam Lange, Antoine Loquet, Britta Laube, David Baker, Dietmar Riedel, Jean-Philippe Demers, Karin Giller, Michael Kolbe, Nikolaos G Sgourakis, Rashmi Gupta, Stefan Becker |
16114 | 2010-02-11 | Chemical Shifts: 1 set Residual Dipolar Couplings: 1 set |
Solution structure of a Ubiquitin/UIM fusion protein | Conformational dynamics and structural plasticity play critical roles in the ubiquitin recognition of a UIM domain. | Angel E Garcia, George I Makhatadze, Mayank M Patel, Nikolaos G Sgourakis, Scott A McCallum |