Entry ID |
Original Release date |
Data summary |
Entry Title |
Citation Title |
Authors |
52269 |
2024-03-28 |
Chemical Shifts: 1 set |
MTMR7 coiled coil domain |
Myotubularin-related-protein-7 inhibits mutant (G12V) K-RAS by direct interaction
|
Alexander Bauer, Andre Zwicky, Birthe B Kragelund, Daniel Saar, Elke Burgermeister, Florian N Rohrbacher, Frank G Zollner, Hazem Ahmed, Jeffrey W Bode, Matthias P Ebert, Matthias Tanriver, Michaela Sohn, Norbert Ponelies, Philipp Riffel, Philip Weidner, Rebecca C Wade, Rony Seger, Simon M Ametamey, Torsten Schroeder, Vijaya R Pattabiraman, Xiaobo Zhou, Yanxiong Yu |
31063 |
2023-03-23 |
Chemical Shifts: 1 set |
Solution structure of Pmu1a |
Pmu1a, a novel spider toxin with dual inhibitory activity at pain targets hNaV 1.7 and hCaV 3 voltage-gated channels
|
C I Schroeder, D T Wilson, E Bourinet, I Vetter, J Chemin, J Giribaldi, J R Deuis, M Tuifua, N L Daly, R Mary, S Dutertre |
30954 |
2022-05-16 |
Chemical Shifts: 1 set |
Mu-conotoxin KIIIA isomer 2 |
Structural and functional insights into the inhibition of human voltage-gated sodium channels by mu-conotoxin KIIIA disulfide isomers
|
C I Schroeder, H NT Tran, I Vetter, J R Dueis, K L McMahon |
30953 |
2022-05-16 |
Chemical Shifts: 1 set |
Native mu-conotoxin KIIIA isomer |
Structural and functional insights into the inhibition of human voltage-gated sodium channels by mu-conotoxin KIIIA disulfide isomers
|
C I Schroeder, H NT Tran, I Vetter, J R Deuis, K L McMahon |
34554 |
2021-09-01 |
Chemical Shifts: 1 set |
NMR solution structure for Tsp1a |
NMR solution structure for Tsp1a
|
A J Agwa, C I Schroeder |
30758 |
2020-10-19 |
Chemical Shifts: 1 set |
Pharmacological characterisation and NMR structure of the novel mu-conotoxin SxIIIC, a potent irreversible NaV channel inhibitor |
Discovery, pharmacological characterisation and NMR structure of the novel mu-conotoxin SxIIIC, a potent irreversible NaV channel inhibitor
|
C I Schroeder, H NT Tran, I Vetter, J R Deuis, K L McMahon, R J Lewis |
30522 |
2018-12-13 |
Chemical Shifts: 1 set |
Solution NMR structure of spider toxin analogue [F5A,M6F,T26L,K28R]GpTx-1 |
Peptide-Membrane Interactions Affect the Inhibitory Potency and Selectivity of Spider Toxins ProTx-II and GpTx-1
|
A H Benfield, A J Agwa, B Wu, C I Schroeder, D J Craik, J Ligutti, K Biswas, L P Miranda, N Lawrence, O Cheneval, S T Henriques |
30521 |
2018-12-13 |
Chemical Shifts: 1 set |
Solution NMR structure of spider toxin analogue [E17K]ProTx-II |
Peptide-Membrane Interactions Affect the Inhibitory Potency and Selectivity of Spider Toxins ProTx-II and GpTx-1
|
A H Benfield, A J Agwa, B Wu, C I Schroeder, D J Craik, J Ligutti, K Biswas, L P Miranda, N Lawrence, O Cheneval, S T Henriques |
30190 |
2017-02-16 |
Chemical Shifts: 1 set |
Solution NMR structure of gHwTx-IV |
Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7.
|
A J Agwa, C I Schroeder, D J Craik, E Deplazes, N Lawrence, O Cheneval, R Chen, S T Henriques |
25847 |
2016-08-22 |
Chemical Shifts: 1 set |
three-dimensional structure of cyclic PVIIA |
Efficient enzymatic cyclization of an inhibitory cystine knot-containing peptide
|
Anne C Conibear, Christina I Schroeder, David J Craik, Frank Bosmans, Olivier Cheneval, Quentin Kaas, Soohyun Kwon |
25804 |
2016-04-04 |
Chemical Shifts: 1 set |
muO-conotoxin MfVIA |
Development of a muO-conotoxin Analogue with Improved Lipid Membrane Interactions and Potency for the Analgesic Target NaV1.8
|
Christina I Schroeder, David J Craik, Irina Vetter, Jennifer R Deuis, Marco C Inserra, Mehdi Mobli, Paul F Alewood, Richard J Lewis, Sonia T Henriques, Zoltan Dekan |