BMRB Entry 30758

Click here to enlarge.

PDB ID: 6x8r
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR30758
MolProbity Validation Chart

NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
All files associated with the entry

Title:
Pharmacological characterisation and NMR structure of the novel mu-conotoxin SxIIIC, a potent irreversible NaV channel inhibitor
Deposition date:
2020-06-01
Original release date:
2020-10-19
Authors:
Schroeder, C.; McMahon, K.
Citation:

Citation: McMahon, K.; Tran, H.; Deuis, J.; Lewis, R.; Vetter, I.; Schroeder, C.. "Discovery, pharmacological characterisation and NMR structure of the novel mu-conotoxin SxIIIC, a potent irreversible NaV channel inhibitor"  Biomedicines 8, E391-E391 (2020).
PubMed: 33023152

Assembly members:

Assembly members:
entity_1, polymer, 23 residues, 2447.836 Da.

Natural source:

Natural source:   Common Name: Conus striolatus   Taxonomy ID: 101315   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Conus striolatus

Experimental source:

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: RGCCNGRGGCSSRWCRDHAR CCX

Data sets:
Data typeCount
13C chemical shifts50
15N chemical shifts16
1H chemical shifts122

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1unit_11

Entities:

Entity 1, unit_1 23 residues - 2447.836 Da.

1   ARGGLYCYSCYSASNGLYARGGLYGLYCYS
2   SERSERARGTRPCYSARGASPHISALAARG
3   CYSCYSNH2

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks