BMRB Entry 15054
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR15054
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Citation: Ronga, Luisa; Palladino, Pasquale; Saviano, Gabriella; Tancredi, Teodorico; Benedetti, Ettore; Ragone, Raffaele; Rossi, Filomena. "Structural characterization of a neurotoxic threonine-rich peptide corresponding to the human prion protein alpha2-helical 180-195 segment, and comparison with full-length alpha2-helix-derived peptides" J. Pept. Sci. 14, 1096-1102 (2008).
PubMed: 18563793
Assembly members:
HPRP-180-195_PEPTIDE, polymer, 16 residues, Formula weight is not available
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: chemical synthesis
Entity Sequences (FASTA):
HPRP-180-195_PEPTIDE: VNITIKQHTVTTTTKG
- assigned_chemical_shifts
| Data type | Count |
| 1H chemical shifts | 106 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | HPRP-180-195 PEPTIDE | 1 |
Entities:
Entity 1, HPRP-180-195 PEPTIDE 16 residues - Formula weight is not available
| 1 | VAL | ASN | ILE | THR | ILE | LYS | GLN | HIS | THR | VAL | ||||
| 2 | THR | THR | THR | THR | LYS | GLY |
Samples:
sample_1: HPRP-180-195 PEPTIDE1 – 2 mM; TRIFLUOROETHANOL-D2, [U-2H], 100%
sample_conditions_1: pH: 5.0; pressure: 1.0 atm; temperature: 300.0 K
Experiments:
| Name | Sample | Sample state | Sample conditions |
|---|---|---|---|
| NOESY | sample_1 | isotropic | sample_conditions_1 |
| TOCSY | sample_1 | isotropic | sample_conditions_1 |
| COSY | sample_1 | isotropic | sample_conditions_1 |
| 15N-HSQC | sample_1 | isotropic | sample_conditions_1 |
Software:
DYANA, P.GUNTERTH - refinement
NMRView, B Johnson, One Moon Scientific - structure solution
NMR spectrometers:
- BRUKER AVANCE 600 MHz
Related Database Links:
| BMRB | 15053 15845 16071 16075 16076 16077 16078 16079 16080 16185 17081 17084 17174 17213 17714 17756 17757 17758 17780 17834 18550 19268 4307 4379 4402 |
| PDB | |
| DBJ | BAA00011 BAA08790 BAD51981 BAE28320 BAE28693 |
| EMBL | CAA58442 CAG46836 CAG46869 CAH92912 CAJ18553 |
| GB | AAA19664 AAA37013 AAA37014 AAA37090 AAA37091 |
| PIR | B34759 |
| REF | NP_000302 NP_001009093 NP_001040617 NP_001073590 NP_001073591 |
| SP | P04156 P04273 P04925 P13852 P40245 |
| TPE | CAJ43807 CAJ43808 |
| AlphaFold | P04156 P04273 P04925 P13852 P40245 |