BMRB Entry 50873

Title:
Structural description of DNA target search by a disordered transcription factor
Deposition date:
2021-04-07
Original release date:
2024-08-28
Authors:
Kelly, Conor Francis; Redfield, Christina; Shammas, Sarah
Citation:

Citation: Kelly, Conor Francis; Kuravsky, Mikhail; Redfield, Christina; Shammas, Sarah. "The transition state for coupled folding and binding of a disordered DNA binding domain resembles the unbound state"  Nucleic Acids Res. ., .-..

Assembly members:

Assembly members:
entity_1, polymer, 56 residues, Formula weight is not available
entity_2, polymer, 14 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pHSG299

Entity Sequences (FASTA):

Data sets:
Data typeCount
13C chemical shifts197
15N chemical shifts57
1H chemical shifts231

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1CREB 285-339, chain 11
2CREB 285-339, chain 21
3CRE DNA2

Entities:

Entity 1, CREB 285-339, chain 1 56 residues - Formula weight is not available

1   GLYLYSARGGLUVALARGLEUMETLYSASN
2   ARGGLUALAALAARGGLUSERARGARGLYS
3   LYSLYSGLUTYRVALLYSSERLEUGLUASN
4   ARGVALALAVALLEUGLUASNGLNASNLYS
5   THRLEUILEGLUGLULEULYSALALEULYS
6   ASPLEUTYRSERHISLYS

Entity 2, CRE DNA 14 residues - Formula weight is not available

1   DADGDADTDGDADCDGDTDC
2   DADTDCDT

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks