BMRB Entry 7364

Title:
Solution Structure of Variable-type Domain of Human Receptor for Advanced Glycation Endproducts
Deposition date:
2007-01-19
Original release date:
2009-02-04
Authors:
Matsumoto, S.; Yoshida, T.; Yasumatsu, I.; Yamamoto, H.; Kobayashi, Y.; Ohkubo, T.
Citation:

Citation: Matsumoto, Shigeyuki; Yoshida, Takuya; Murata, Hiroko; Harada, Shusaku; Fujita, Naoko; Nakamura, Shota; Yamamoto, Yasuhiko; Watanabe, Takuo; Yonekura, Hideto; Yamamoto, Hiroshi; Ohkubo, Tadayasu; Kobayashi, Yuji. "Solution Structure of the Variable-Type Domain of the Receptor for Advanced Glycation End Products: New Insight into AGE-RAGE Interaction"  Biochemistry 47, 12299-12311 (2008).
PubMed: 19032093

Assembly members:

Assembly members:
Advanced_glycosylation_end_product-specific_receptor, polymer, 101 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: human   Taxonomy ID: 9606   Superkingdom: not available   Kingdom: Eukaryota   Genus/species: Metazoa Homo

Experimental source:

Experimental source:   Production method: recombinant technology

Entity Sequences (FASTA):

Entity Sequences (FASTA):
Advanced_glycosylation_end_product-specific_receptor: AMAQNITARIGEPLVLKCKG APKKPPQRLEWKLNTGRTEA WKVLSPQGGGPWDSVARVLP NGSLFLPAVGIQDEGIFRCQ AMNRNGKETKSNYRVRVYQI P

Data sets:
Data typeCount
13C chemical shifts401
15N chemical shifts82
1H chemical shifts554

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1AG_Endproducts1

Entities:

Entity 1, AG_Endproducts 101 residues - Formula weight is not available

1   ALAMETALAGLNASNILETHRALAARGILE
2   GLYGLUPROLEUVALLEULYSCYSLYSGLY
3   ALAPROLYSLYSPROPROGLNARGLEUGLU
4   TRPLYSLEUASNTHRGLYARGTHRGLUALA
5   TRPLYSVALLEUSERPROGLNGLYGLYGLY
6   PROTRPASPSERVALALAARGVALLEUPRO
7   ASNGLYSERLEUPHELEUPROALAVALGLY
8   ILEGLNASPGLUGLYILEPHEARGCYSGLN
9   ALAMETASNARGASNGLYLYSGLUTHRLYS
10   SERASNTYRARGVALARGVALTYRGLNILE
11   PRO

Samples:

sample_1: AG_Endproducts, [U-13C; U-15N], 0.2 mM; phosphate buffer 20 mM; Na2SO4 100 mM; D2O 10%; H2O 90%

sample_2: AG_Endproducts, [U-13C; U-15N], 0.2 mM; phosphate buffer 20 mM; Na2SO4 100 mM; D2O 100%

sample_conditions_1: pH: 7.5; pressure: 1 atm; temperature: 298 K

Experiments:

NameSampleSample stateSample conditions
3D_13C-separated_NOESYnot availableisotropicsample_conditions_1
3D_15N-separated_NOESYnot availableisotropicsample_conditions_1
2D NOESYnot availableisotropicsample_conditions_1
2D TOCSYnot availableisotropicsample_conditions_1

Software:

CNS v1.1, Brunger - refinement

NMR spectrometers:

  • Varian INOVA 600 MHz
  • Varian INOVA 500 MHz

Related Database Links:

BMRB 17378 19739 19953
PDB
DBJ BAA05958 BAA89369 BAC65465 BAG35995 BAG60385
GB AAA03574 AAB47491 AAH20669 AAX07272 AAX07273
REF NP_001127 NP_001192046 NP_001193858 NP_001193863 NP_001193865
SP Q15109
AlphaFold Q15109

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks