BMRB Entry 7259

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PDB ID: 2htf
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR7259
MolProbity Validation Chart

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Title:
The solution structure of the BRCT domain from human polymerase reveals homology with the TdT BRCT domain
Deposition date:
2006-08-10
Original release date:
2007-11-21
Authors:
DeRose, E.; Clarkson, M.; Gilmore, S.; Ramsden, D.; Mueller, G.; London, R.; Lee, A.
Citation:

Citation: DeRose, E.; Clarkson, M.; Gilmore, S.; Galban, C.; Tripathy, A.; Havener, J.; Mueller, G.; Ramsden, D.; London, R.; Lee, A.. "Solution Structure of Polymerase mu's BRCT Domain Reveals an Element Essential for Its Role in Nonhomologous End Joining."  Biochemistry 46, 12100-12110 (2007).
PubMed: 17915942

Assembly members:

Assembly members:
DNA polymerase mu (E.C.2.7.7.7), polymer, 105 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli

Entity Sequences (FASTA):

Entity Sequences (FASTA):
DNA polymerase mu (E.C.2.7.7.7): GTPPSTRFPGVAIYLVEPRM GRSRRAFLTGLARSKGFRVL DACSSEATHVVMEETSAEEA VSWQERRMAAAPPGCTPPAL LDISWLTESLGAGQPVPVEC RHRLE

Data sets:
Data typeCount
13C chemical shifts413
15N chemical shifts100
1H chemical shifts651

Additional metadata:

  • Assembly
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  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1DNA polymerase mu1

Entities:

Entity 1, DNA polymerase mu 105 residues - Formula weight is not available

1   GLYTHRPROPROSERTHRARGPHEPROGLY
2   VALALAILETYRLEUVALGLUPROARGMET
3   GLYARGSERARGARGALAPHELEUTHRGLY
4   LEUALAARGSERLYSGLYPHEARGVALLEU
5   ASPALACYSSERSERGLUALATHRHISVAL
6   VALMETGLUGLUTHRSERALAGLUGLUALA
7   VALSERTRPGLNGLUARGARGMETALAALA
8   ALAPROPROGLYCYSTHRPROPROALALEU
9   LEUASPILESERTRPLEUTHRGLUSERLEU
10   GLYALAGLYGLNPROVALPROVALGLUCYS
11   ARGHISARGLEUGLU

Related Database Links:

PDB 2DUN 2HTF
DBJ BAB14353 BAF84327 BAG57686
EMBL CAB65075
GB AAF26284 AAH26306 AAH49202 AAH62590 AAW65376
REF NP_001271259 NP_001271260 NP_037416 XP_001142751 XP_001142835
SP Q9NP87
AlphaFold Q9NP87

Download HSQC peak lists in one of the following formats:
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