BMRB Entry 5057

Name: 1H Chemical Shift Assignments for Alzheimer peptide Ab(1-40)
Published: 2002-01-23

Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR5057

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Bioinformatics (2015) 31 (8): 1322-1324 doi:10.1093/bioinformatics/btu829

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Title:

1H Chemical Shift Assignments for Alzheimer peptide Ab(1-40)

Deposition date:

2001-06-14

Original release date:

2002-01-23

Authors:

Riek, Roland; Guntert, Peter; Dobeli, Heinz; Wipf, Beat; Wuthrich, Kurt

Citation:

Citation: Riek, Roland; Guntert, Peter; Dobeli, Heinz; Wipf, Beat; Wuthrich, Kurt. "NMR Studies in Aqueous Solution Fail to Identify Significant Conformational Differences between the Monomeric Forms of Two Alzheimer Peptides with Widely Different Plaque-competence, A beta(1-40)(ox) and A beta(1-42)(ox)" Eur. J. Biochem. 268, 5930-5936 (2001).
PubMed: 11722581

Assembly members:

Assembly members:
Ab, polymer, 40 residues, Formula weight is not available

Natural source:

Natural source: Common Name: human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens

Experimental source:

Experimental source: Production method: recombinant technology

Entity Sequences (FASTA):

Entity Sequences (FASTA):
Ab: DAEFRHDSGYEVHHQKLVFF AEDVGSNKGAIIGLXVGGVV

Data sets:

assigned_chemical_shifts
- shift_set_1

Data type	Count
1H chemical shifts	212

Additional metadata:

Assembly
Samples and Experiments
Software
Spectrometers
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Assembly:

Entity Assembly ID	Entity Name	Entity ID
1	Ab(1-40)	1

Entities:

Entity 1, Ab(1-40) 40 residues - Formula weight is not available

1	ASP	ALA	GLU	PHE	ARG	HIS	ASP	SER	GLY	TYR
2	GLU	VAL	HIS	HIS	GLN	LYS	LEU	VAL	PHE	PHE
3	ALA	GLU	ASP	VAL	GLY	SER	ASN	LYS	GLY	ALA
4	ILE	ILE	GLY	LEU	SME	VAL	GLY	GLY	VAL	VAL

Samples:

sample_1: Ab mM

Ex-cond_1: pH: 6.4; temperature: 281 K

Experiments:

Name	Sample	Sample state	Sample conditions
not available	sample_1	not available	Ex-cond_1

Software:

No software information available

NMR spectrometers:

Bruker DRX 750 MHz

Related Database Links:

BMRB	11435 15775 17159 17186 17764 17793 17794 17795 17796 18052 18127 18128 18129 18131 19009 19309 5400 6257 6554
PDB	1AMB 1AMC 1AML 1BA4 1BA6 1HZ3 1IYT 1Z0Q 2BEG 2G47 2LFM 2LMN 2LMO 2LMP 2LMQ 2LP1 2M4J 2M9R 2M9S 2OTK 2WK3 3BAE 3IFN 4HIX 4M1C 4NGE 4ONG
DBJ	BAA22264 BAA84580 BAD51938 BAE01907 BAG10647
EMBL	CAA30050 CAA31830 CAA39589 CAA39590 CAA39591
GB	AAA35540 AAA36829 AAA51564 AAA51722 AAA51726
PIR	A60045 D60045 E60045 G60045 PQ0438
PRF	1303338A 1403400A 1405204A 1507304A 1507304B
REF	NP_000475 NP_001006601 NP_001013036 NP_001070264 NP_001127014
SP	P05067 P53601 P79307 Q28053 Q28280
TPG	DAA33655
AlphaFold	P05067 P53601 P79307 Q28053 Q28280

1	ASP	ALA	GLU	PHE	ARG	HIS	ASP	SER	GLY	TYR
2	GLU	VAL	HIS	HIS	GLN	LYS	LEU	VAL	PHE	PHE
3	ALA	GLU	ASP	VAL	GLY	SER	ASN	LYS	GLY	ALA
4	ILE	ILE	GLY	LEU	SME	VAL	GLY	GLY	VAL	VAL

1	ASP	ALA	GLU	PHE	ARG	HIS	ASP	SER	GLY	TYR
2	GLU	VAL	HIS	HIS	GLN	LYS	LEU	VAL	PHE	PHE
3	ALA	GLU	ASP	VAL	GLY	SER	ASN	LYS	GLY	ALA
4	ILE	ILE	GLY	LEU	SME	VAL	GLY	GLY	VAL	VAL

1	ASP	ALA	GLU	PHE	ARG	HIS	ASP	SER	GLY	TYR
2	GLU	VAL	HIS	HIS	GLN	LYS	LEU	VAL	PHE	PHE
3	ALA	GLU	ASP	VAL	GLY	SER	ASN	LYS	GLY	ALA
4	ILE	ILE	GLY	LEU	SME	VAL	GLY	GLY	VAL	VAL