BMRB Entry 30850

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PDB ID: 7lie
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR30850
MolProbity Validation Chart

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Title:
The isolated chicken ASIC1a thumb domain (ATD-c1a) retains the structure and ligand binding properties of the full length chicken ASIC1a
Deposition date:
2021-01-27
Original release date:
2022-08-05
Authors:
Mishra, B.; Mobli, M.
Citation:

Citation: Mishra, B.; Mobli, M.. "A reductionist approach for studying the ASIC thumb domain to screen for channel modulators as novel therapeutic leads"  .

Assembly members:

Assembly members:
entity_1, polymer, 78 residues, 8921.990 Da.

Natural source:

Natural source:   Common Name: Chicken   Taxonomy ID: 9031   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Gallus gallus

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: SCKATTGDSEFYDTYSITAC RIDCETRYLVENCNCRMVHM PGDAPYCTPEQYKECADPAL DFLVEKDNEYCVCEMPCN

Data typeCount
13C chemical shifts342
15N chemical shifts80
1H chemical shifts502

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1unit_11

Entities:

Entity 1, unit_1 78 residues - 8921.990 Da.

1   SERCYSLYSALATHRTHRGLYASPSERGLU
2   PHETYRASPTHRTYRSERILETHRALACYS
3   ARGILEASPCYSGLUTHRARGTYRLEUVAL
4   GLUASNCYSASNCYSARGMETVALHISMET
5   PROGLYASPALAPROTYRCYSTHRPROGLU
6   GLNTYRLYSGLUCYSALAASPPROALALEU
7   ASPPHELEUVALGLULYSASPASNGLUTYR
8   CYSVALCYSGLUMETPROCYSASN

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