BMRB Entry 19060

Title:
Atomic-resolution structure of a triplet cross-beta amyloid fibril
Deposition date:
2013-02-27
Original release date:
2013-12-02
Authors:
Fitzpatrick, Anthony; Debelouchina, Galia; Bayro, Marvin; Clare, Daniel; Caporini, Marc; Bajaj, Vikram; Jaroniec, Christopher; Wang, Luchun; Ladizhansky, Vladimir; Muller, Shirley; MacPhee, Cait; Waudby, Christopher; Mott, Helen; de Simone, Alfonso; Knowles, Tuomas; Saibil, Helen; Vendruscolo, Michele; Orlova, Elena; Griffin, Robert; Dobson, Christopher
Citation:

Citation: Fitzpatrick, Anthony; Debelouchina, Galia; Bayro, Marvin; Clare, Daniel; Caporini, Marc; Bajaj, Vikram; Jaroniec, Christopher; Wang, Luchun; Ladizhansky, Vladimir; Muller, Shirley; MacPhee, Cait; Waudby, Christopher; Mott, Helen; de Simone, Alfonso; Knowles, Tuomas; Saibil, Helen; Vendruscolo, Michele; Orlova, Elena; Griffin, Robert; Dobson, Christopher. "Atomic structure and hierarchical assembly of a cross-beta amyloid fibril"  Proc. Natl. Acad. Sci. U.S.A. 110, 5468-5473 (2013).
PubMed: 23513222

Assembly members:

Assembly members:
TTR(105-115), polymer, 11 residues, 1198.378 Da.

Natural source:

Natural source:   Common Name: Norway rat   Taxonomy ID: 10116   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Rattus norvegicus

Experimental source:

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
TTR(105-115): YTIAALLSPYS

Data sets:
Data typeCount
13C chemical shifts56
15N chemical shifts9

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1triplet cross-beta amyloid fibril1

Entities:

Entity 1, triplet cross-beta amyloid fibril 11 residues - 1198.378 Da.

1   TYRTHRILEALAALALEULEUSERPROTYR
2   SER