BMRB Entry 18654
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PDB ID: 2lwz
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR18654
MolProbity Validation Chart
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NMR-STAR v3 text file.
XML gzip file.
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Citation: Yang, Yanwu; Wan, Zhu-li; Hua, Qing-xin; Phillips, Nelson; Huang, Kun; Yeh, I-Ju; Liu, Yule; Hu, Shi-Quan; Hattier, Thomas; Whittaker, Jonathan; Weiss, Michael. "Dynamic repair of an amyloidogenic protein: insulin fibrillation is blocked by tethering a nascent alpha-helix" .
Assembly members:
Single-chain Insulin, polymer, 57 residues, 6382.218 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Pichia pastoris Vector: pPICz
Entity Sequences (FASTA):
Single-chain Insulin: FVNQHLCGSDLVEALYLVCG
ERGFFYTDPTGGGPRRGIVE
QCCHSICSLYQLENYCN
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 191 |
| 15N chemical shifts | 54 |
| 1H chemical shifts | 368 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | Single-chain Insulin | 1 |
Entities:
Entity 1, Single-chain Insulin 57 residues - 6382.218 Da.
| 1 | PHE | VAL | ASN | GLN | HIS | LEU | CYS | GLY | SER | ASP | ||||
| 2 | LEU | VAL | GLU | ALA | LEU | TYR | LEU | VAL | CYS | GLY | ||||
| 3 | GLU | ARG | GLY | PHE | PHE | TYR | THR | ASP | PRO | THR | ||||
| 4 | GLY | GLY | GLY | PRO | ARG | ARG | GLY | ILE | VAL | GLU | ||||
| 5 | GLN | CYS | CYS | HIS | SER | ILE | CYS | SER | LEU | TYR | ||||
| 6 | GLN | LEU | GLU | ASN | TYR | CYS | ASN |
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