BMRB Entry 18374

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PDB ID: 2lri
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full, LACS, SPARTA
BMRB Entry DOI: doi:10.13018/BMR18374
MolProbity Validation Chart

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Title:
NMR structure of the second PHD finger of AIRE (AIRE-PHD2)
Deposition date:
2012-04-03
Original release date:
2012-10-12
Authors:
Gaetani, Massimiliano; Chignola, Francesca; Mollica, Luca; Quilici, Giacomo; Mannella, Valeria; Spiliotopoulos, Dimitrios; Musco, Giovanna
Citation:

Citation: Gaetani, Massimiliano; Matafora, Vittoria; Saare, Mario; Spiliotopoulos, Dimitrios; Mollica, Luca; Quilici, Giacomo; Chignola, Francesca; Mannella, Valeria; Zucchelli, Chiara; Peterson, Part; Bachi, Angela; Musco, Giovanna. "AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome."  Nucleic Acids Res. 40, 11756-11768 (2012).
PubMed: 23074189

Assembly members:

Assembly members:
AIRE-PHD2, polymer, 66 residues, 6810.711 Da.
ZINC ION, non-polymer, 65.409 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET-24d

Entity Sequences (FASTA):

Entity Sequences (FASTA):
AIRE-PHD2: GAMEGQQNLAPGARCGVCGD GTDVLRCTHCAAAFHWRCHF PAGTSRPGTGLRCRSCSGDV TPAPVE

Data sets:
Data typeCount
13C chemical shifts192
15N chemical shifts62
1H chemical shifts381

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1AIRE-PHD21
2ZINC ION_12
3ZINC ION_22

Entities:

Entity 1, AIRE-PHD2 66 residues - 6810.711 Da.

1   GLYALAMETGLUGLYGLNGLNASNLEUALA
2   PROGLYALAARGCYSGLYVALCYSGLYASP
3   GLYTHRASPVALLEUARGCYSTHRHISCYS
4   ALAALAALAPHEHISTRPARGCYSHISPHE
5   PROALAGLYTHRSERARGPROGLYTHRGLY
6   LEUARGCYSARGSERCYSSERGLYASPVAL
7   THRPROALAPROVALGLU

Entity 2, ZINC ION_1 - Zn - 65.409 Da.

1   ZN

Related Database Links:

PDB 2LRI
DBJ BAA23988 BAA23989 BAA23990 BAA23991 BAA95560
EMBL CAB10790
GB AAI37269 AAI37271 AIC54015 EAX09441 EAX09443
REF NP_000374 XP_004062941 XP_008975805 XP_009439558 XP_011527853
SP O43918
AlphaFold O43918

Download HSQC peak lists in one of the following formats:
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