BMRB Entry 16596

Title:
First PBZ domain of human APLF protein
Deposition date:
2009-11-04
Original release date:
2010-01-28
Authors:
Neuhaus, David; Eustermann, Sebastian; Brockmann, Christoph; Yang, Ji-Chun
Citation:

Citation: Eustermann, Sebastian; Brockmann, Christoph; Mehrotra, Pawan Vinod; Yang, Ji-Chun; Loakes, David; West, Stephen; Ahel, Ivan; Neuhaus, David. "Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose)."  Nat. Struct. Mol. Biol. 17, 241-243 (2010).
PubMed: 20098424

Assembly members:

Assembly members:
APLF_363-451, polymer, 89 residues, 5952.459 Da.
ZN, non-polymer, 65.409 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pGEX-6P-1

Entity Sequences (FASTA):

Data sets:
Data typeCount
13C chemical shifts288
15N chemical shifts87
1H chemical shifts562

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1APLF_363-4511
2ZINC ION, 12
3ZINC ION, 22

Entities:

Entity 1, APLF_363-451 89 residues - 5952.459 Da.

1   GLYPROLEUGLYSERGLYSERGLUGLYASN
2   LYSVALLYSARGTHRSERCYSMETTYRGLY
3   ALAASNCYSTYRARGLYSASNPROVALHIS
4   PHEGLNHISPHESERHISPROGLYASPSER
5   ASPTYRGLYGLYVALGLNILEVALGLYGLN
6   ASPGLUTHRASPASPARGPROGLUCYSPRO
7   TYRGLYPROSERCYSTYRARGLYSASNPRO
8   GLNHISLYSILEGLUTYRARGHISASNTHR
9   LEUPROVALARGASNVALLEUASPGLU

Entity 2, ZINC ION, 1 - Zn - 65.409 Da.

1   ZN

Related Database Links:

BMRB 16744
PDB 2KQB 2KQC 2KQD 2KQE 2KUO
DBJ BAF83530
GB AAH41144 AAY24113 ADZ15607 AIC53375 EAW99871
REF NP_775816 XP_002799328 XP_003830966 XP_004029419 XP_005575758
SP Q8IW19
AlphaFold Q8IW19 Q8IW19 Q8IW19 Q8IW19

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks