Entry ID |
Original Release date |
Data summary |
Entry Title |
Citation Title |
Authors |
30755 |
2020-08-03 |
Chemical Shifts: 1 set |
B24Y DKP insulin |
Evolution of insulin at the edge of foldability and its medical implications
|
Balamurugan Dhayalan, Faramarz Ismail-Beigi, Huan Guo, Jinhong Sun, Leena Haataja, Leili Rahimi, Michael A Weiss, Ming Liu, Nalinda P Wickramasinghe, Nelson B Phillips, Nischay K Rege, Peter Arvan, Yanwu Yang, Yen-Shan S Chen |
30314 |
2017-11-08 |
Chemical Shifts: 1 set |
Solution Structure and Dynamics of an Ultra-Stable Single-Chain Insulin Analog STUDIES OF AN ENGINEERED MONOMER AND IMPLICATIONS FOR RECEPTOR BINDING |
Solution structure of an ultra-stable single-chain insulin analog connects protein dynamics to a novel mechanism of receptor binding
|
Brian J Smith, Faramarz Ismail-Beigi, Kelley Carr, Michael A Weiss, Michael C Lawrence, Michael D Glidden, Nalinda P Wickramasinghe, Nelson B Phillips, Nicholas A Smith, Yanwu Yang |
19979 |
2014-12-22 |
Chemical Shifts: 1 set |
Solution structure of B24G insulin |
Protective hinge in insulin opens to enable its receptor engagement
|
Brian J Smith, Charles T Roberts, Colin W Ward, Donald F Steiner, Faramarz Ismail-Beigi, John G Menting, Jonathan Whittaker, Julie M Carroll, Linda J Whittaker, Michael A Weiss, Michael C Lawrence, Nalinda P Wickramasinghe, Natalie Strokes, Nelson B Phillips, Satya P Yadav, Shu Jin Chan, Vijay Pandyarajan, Virander S Chauhan, Wieslawa Milewski, Yanwu Yang, Zhu-li Wan |
19822 |
2014-08-25 |
Chemical Shifts: 1 set |
NMR structure of B25-(alpha, beta)-dehydro-phenylalanine insulin |
Protective hinge in insulin opens to enable its receptor engagement
|
Brian J Smith, Charles T Roberts, Colin W Ward, Donald F Steiner, Faramarz Ismail-Beigi, John G Menting, Jonathan Whittaker, Julie M Carroll, Linda J Whittaker, Michael A Weiss, Michael C Lawrence, Nalinda P Wickramasinghe, Natalie Strokes, Nelson B Phillips, Satya P Yadav, ShuJin Chan, Vijay Pandyarajan, Virander S Chauhan, Wieslawa Milewski, Yanwu Yang, Zhu-li Wan |
16343 |
2010-05-19 |
Chemical Shifts: 1 set |
NMR STRUCTURE OF HUMAN INSULIN MUTANT GLU-B21-D-GLU, HIS-B10 ASP PRO-B28-LYS, LYS-B29-PRO, 20 STRUCTURES |
An Achilles' heel in an amyloidogenic protein and its repair: insulin fibrillation and therapeutic design.
|
Aneta Petkova, Bin Xu, Faramarz Ismail-Beigi, I-Ju Ye, Jonathan Whittaker, Kun Huang, Michael A Weiss, Nelson B Phillips, Panayotis G Katsoyannis, Qing-Xin Hua, Robert B Mackin, Robert Tycko, Shi-Quan Hu, Yanwu Yang, Ying-Chi Chu |