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Entry ID Original Release date Data summary Entry Title Citation Title Authors
50090 2020-02-21 Chemical Shifts: 1 set
G335D TDP43_267-414 TDP-43 alpha-helical structure tunes liquid-liquid phase separation and function Download bibtex for citation iamge Alexander E Conicella, Alexandra M D'Ordine, Gregory L Dignon, Gul H Zerze, Hermann Broder B Schmidt, Jeetain Mittal, Nicolas L Fawzi, Rajat Rohatgi, Young C Kim, Yuna M Ayala
27789 2019-10-30 Chemical Shifts: 1 set
G335S TDP-43_267-414 TDP-43 alpha-helical structure tunes liquid-liquid phase separation and function Download bibtex for citation iamge Alexander E Conicella, Alexandra M D'Ordine, Gregory L Dignon, Gul H Zerze, Hermann Broder B Schmidt, Jeetain Mittal, Nicolas L Fawzi, Rajat Rohatgi, Young C Kim, Yuna M Ayala
27790 2019-10-30 Chemical Shifts: 1 set
G338A TDP-43_267-414 TDP-43 alpha-helical structure tunes liquid-liquid phase separation and function Download bibtex for citation iamge Alexander E Conicella, Alexandra M D'Ordine, Gregory L Dignon, Gul H Zerze, Hermann Broder B Schmidt, Jeetain Mittal, Nicolas L Fawzi, Rajat Rohatgi, Young C Kim, Yuna M Ayala
27788 2019-10-30 Chemical Shifts: 1 set
G335N TDP-43_267-414 TDP-43 alpha-helical structure tunes liquid-liquid phase separation and function Download bibtex for citation iamge Alexander E Conicella, Alexandra M D'Ordine, Gregory L Dignon, Gul H Zerze, Hermann Broder B Schmidt, Jeetain Mittal, Nicolas L Fawzi, Rajat Rohatgi, Young C Kim, Yuna M Ayala
27750 2019-10-30 Chemical Shifts: 1 set
G335A TDP-43_267-414 TDP-43 alpha-helical structure tunes liquid-liquid phase separation and function Download bibtex for citation iamge Alexander E Conicella, Alexandra M D'Ordine, Gregory L Dignon, Gul H Zerze, Hermann Broder B Schmidt, Jeetain Mittal, Nicolas L Fawzi, Rajat Rohatgi, Young C Kim, Yuna M Ayala
27751 2019-10-30 Chemical Shifts: 1 set
G335N TDP-43_267-414 TDP-43 alpha-helical structure tunes liquid-liquid phase separation and function Download bibtex for citation iamge Alexander E Conicella, Alexandra M D'Ordine, Gregory L Dignon, Gul H Zerze, Hermann Broder B Schmidt, Jeetain Mittal, Nicolas L Fawzi, Rajat Rohatgi, Young C Kim, Yuna M Ayala
27299 2018-01-11 Chemical Shifts: 1 set
hnRNPA2 P298L low complexity domain 190-341 backbone and Cbeta chemical shifts Disease mutation, protein interactions, and posttranslational modifications modulate hnRNPA2 liquid-liquid phase separation Download bibtex for citation iamge Alexander E Conicella, Charlene V Chabata, Gregory L Dignon, Gul H Zerze, Jeetain Mittal, Joshua Amaya, Kathleen A Burke, Nicolas L Fawzi, Rute Silva, Veronica H Ryan
30345 2018-02-21 Chemical Shifts: 2 sets
Solution structure of TDP-43 N-terminal domain dimer. A single N-terminal phosphomimic disrupts TDP-43 polymerization, phase separation and RNA splicing Download bibtex for citation iamge Ailin Wang, Alexander E Conicella, Amanda Nourse, Ashley N Reeb, Daniel Ramirez Montero, Erik W Martin, Frank Shewmaker, Hermann Broder B Schmidt, Mandar T Naik, Nicolas L Fawzi, Rajat Rohatgi, Shannon N Rhoads, Tanja Mittag, Veronica H Ryan, Yuna M Ayala
27124 2018-01-11 Chemical Shifts: 1 set
hnRNPA2 D290V low complexity domain 190-341 backbone and Cbeta chemical shifts Disease mutation, protein interactions, and posttranslational modifications modulate hnRNPA2 liquid-liquid phase separation Download bibtex for citation iamge Alexander E Conicella, Charlene V Chabata, Gregory L Dignon, Gul H Zerze, Jeetain Mittal, Joshua Amaya, Kathleen A Burke, Nicolas L Fawzi, Rute Silva, Veronica H Ryan
27123 2018-01-11 Chemical Shifts: 1 set
hnRNPA2 low complexity domain 190-341 backbone and Cbeta chemical shifts Disease mutation, protein interactions, and posttranslational modifications modulate hnRNPA2 liquid-liquid phase separation Download bibtex for citation iamge Alexander E Conicella, Charlene V Chabata, Gregory L Dignon, Gul H Zerze, Jeetain Mittal, Joshua Amaya, Kathleen A Burke, Nicolas L Fawzi, Rute Silva, Veronica H Ryan
27125 2017-08-02 Chemical Shifts: 1 set
FUS low complexity domain with 12 phosphomimetic S/T to E mutations Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity Download bibtex for citation iamge Abigail M Janke, Alexander E Conicella, Frank Shewmaker, Gregory L Dignon, Gul H Zerze, Jeetain Mittal, Kathleen A Burke, Nicolas L Fawzi, Robert B Best, Robert N Cole, Robert O'Meally, Shannon N Rhoads, Veronica H Ryan, Wenwei Zheng, Zachary Monahan
27063 2017-10-04 Chemical Shifts: 1 set
Heteronuclear NOE Values: 1 set
T1 Relaxation Values: 1 set
T2 Relaxation Values: 1 set
Degenerate heptads 27-52 of human RNA polymerase II C-terminal domain (DNA-directed RNA polymerase II subunit RPB1): assignments and backbone relaxation Lysines in RNA polymerase II C-terminal domain contribute to TAF15 fibril recruitment Download bibtex for citation iamge Abigail M Janke, Alexander E Conicella, Dahee Seo, Jeetain Mittal, Kathleen A Burke, Nicolas L Fawzi, Vahid Rahmanian
26831 2016-08-19 Chemical Shifts: 1 set
Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 C-terminal domain engineered variant M337P ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain Download bibtex for citation iamge Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi
26830 2016-08-19 Chemical Shifts: 1 set
Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 C-terminal domain ALS-associated variant M337V ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain Download bibtex for citation iamge Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi
26829 2016-08-19 Chemical Shifts: 1 set
Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 C-terminal domain ALS-associated variant Q331K ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain Download bibtex for citation iamge Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi
26828 2016-08-19 Chemical Shifts: 1 set
Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 C-terminal domain engineered variant A326P ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain Download bibtex for citation iamge Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi
26827 2016-08-19 Chemical Shifts: 1 set
Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 C-terminal domain ALS-associated variant A321V ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain Download bibtex for citation iamge Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi
26826 2016-08-19 Chemical Shifts: 1 set
Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 C-terminal domain ALS-associated variant A321G ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain Download bibtex for citation iamge Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi
26823 2016-08-19 Chemical Shifts: 2 sets
Coupling Constants: 1 set
Heteronuclear NOE Values: 2 sets
T1 Relaxation Values: 2 sets
T2 Relaxation Values: 2 sets
Backbone 1H, 13C, and 15N Chemical Shift Assignments, HNHA scalar coupling, and 15N backbone relaxation data for TDP-43 C-terminal domain wild type ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain Download bibtex for citation iamge Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi