BMRB Entry 5953
Chem Shift validation: AVS_anomalous, AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR5953
NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
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Citation: Ilangovan, Udayar; Deep, Shashank; Hinck, Cynthia; Hinck, Andrew. "Letter to the Editor: Sequential Resonance Assignments of the Extracellular Domain
of the Human TGFbeta type II Receptor in Complex with Monomeric TGFbeta3 " J. Biomol. NMR 29, 103-104 (2004).
PubMed: 15017149
Assembly members:
Transforming Growth Factor type II Receptor, polymer, 116 residues, Formula weight is not available
Transforming Growth Factor- Beta 3, polymer, 112 residues, Formula weight is not available
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology
Entity Sequences (FASTA):
Transforming Growth Factor type II Receptor: AVKFPQLCKFCDVRFSTCDN
QKSCMSNCSITSICEKPQEV
CVAVWRKNDENITLETVCHD
PKLPYHDFILEDAASPKCIM
KEKKKPGETFFMCSCSSDEC
NDNIIFSEEYNTSNPE
Transforming Growth Factor- Beta 3: ALDTNYCFRNLEENCCVRPL
YIDFRQDLGWKWVHEPKGYY
ANFCSGPCPYLRSSDTTHST
VLGLYNTLNPEASASPSCVP
QDLEPLTILYYVGRTPKVEQ
LSNMVVKSCKCS
- assigned_chemical_shifts
| Data type | Count |
| 1H chemical shifts | 171 |
| 13C chemical shifts | 326 |
| 15N chemical shifts | 93 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | tgfb type II receptor | 1 |
| 2 | tgfb3 monomer | 2 |
Entities:
Entity 1, tgfb type II receptor 116 residues - Formula weight is not available
| 1 | ALA | VAL | LYS | PHE | PRO | GLN | LEU | CYS | LYS | PHE | ||||
| 2 | CYS | ASP | VAL | ARG | PHE | SER | THR | CYS | ASP | ASN | ||||
| 3 | GLN | LYS | SER | CYS | MET | SER | ASN | CYS | SER | ILE | ||||
| 4 | THR | SER | ILE | CYS | GLU | LYS | PRO | GLN | GLU | VAL | ||||
| 5 | CYS | VAL | ALA | VAL | TRP | ARG | LYS | ASN | ASP | GLU | ||||
| 6 | ASN | ILE | THR | LEU | GLU | THR | VAL | CYS | HIS | ASP | ||||
| 7 | PRO | LYS | LEU | PRO | TYR | HIS | ASP | PHE | ILE | LEU | ||||
| 8 | GLU | ASP | ALA | ALA | SER | PRO | LYS | CYS | ILE | MET | ||||
| 9 | LYS | GLU | LYS | LYS | LYS | PRO | GLY | GLU | THR | PHE | ||||
| 10 | PHE | MET | CYS | SER | CYS | SER | SER | ASP | GLU | CYS | ||||
| 11 | ASN | ASP | ASN | ILE | ILE | PHE | SER | GLU | GLU | TYR | ||||
| 12 | ASN | THR | SER | ASN | PRO | GLU |
Entity 2, tgfb3 monomer 112 residues - Formula weight is not available
| 1 | ALA | LEU | ASP | THR | ASN | TYR | CYS | PHE | ARG | ASN | ||||
| 2 | LEU | GLU | GLU | ASN | CYS | CYS | VAL | ARG | PRO | LEU | ||||
| 3 | TYR | ILE | ASP | PHE | ARG | GLN | ASP | LEU | GLY | TRP | ||||
| 4 | LYS | TRP | VAL | HIS | GLU | PRO | LYS | GLY | TYR | TYR | ||||
| 5 | ALA | ASN | PHE | CYS | SER | GLY | PRO | CYS | PRO | TYR | ||||
| 6 | LEU | ARG | SER | SER | ASP | THR | THR | HIS | SER | THR | ||||
| 7 | VAL | LEU | GLY | LEU | TYR | ASN | THR | LEU | ASN | PRO | ||||
| 8 | GLU | ALA | SER | ALA | SER | PRO | SER | CYS | VAL | PRO | ||||
| 9 | GLN | ASP | LEU | GLU | PRO | LEU | THR | ILE | LEU | TYR | ||||
| 10 | TYR | VAL | GLY | ARG | THR | PRO | LYS | VAL | GLU | GLN | ||||
| 11 | LEU | SER | ASN | MET | VAL | VAL | LYS | SER | CYS | LYS | ||||
| 12 | CYS | SER |
Samples:
bound_sample_1: Transforming Growth Factor type II Receptor0.5 – 0.7 mM; Transforming Growth Factor- Beta 30.5 – 0.7 mM
bound_sample_2: Transforming Growth Factor type II Receptor 0.7 mM; Transforming Growth Factor- Beta 3 0.7 mM
Expt_condition_1: pH: 6.6; temperature: 312 K
Experiments:
| Name | Sample | Sample state | Sample conditions |
|---|---|---|---|
| HNCA | not available | not available | not available |
| HN(CO)CA | not available | not available | not available |
| HNCACB | not available | not available | not available |
| HN(CO)CACB | not available | not available | not available |
| C(CO)NH | not available | not available | not available |
| HC(CO)NH | not available | not available | not available |
| HNCO | not available | not available | not available |
| HN(CA)CO | not available | not available | not available |
| CT-13C-HSQC | not available | not available | not available |
Software:
NMRPIPeE - processing
NMRVIEW v4.1.3 - analyzing
NMR spectrometers:
- Bruker DRX 700 MHz
- Bruker DRX 600 MHz
Related Database Links:
| BMRB | 4411 4411 |
| PDB | |
| DBJ | BAE21215 BAE26357 BAE28523 BAE36326 BAE36968 BAE36968 BAE36326 BAE28523 BAE26357 BAE21215 |
| EMBL | CAA32362 CAA33024 CAR70088 CAA33024 CAA32362 |
| GB | AAA40422 AAA49089 AAA61161 AAA67915 AAC79727 |
| REF | NP_001094653 NP_001244404 NP_003230 NP_033394 NP_037306 XP_001100053 NP_037306 NP_033394 NP_003230 NP_001094653 |
| SP | P10600 P17125 Q07258 |
| TPG | DAA25016 |
| SWISS-PROT | Q07258 P17125 P10600 |
| GenBank | AAF73231 AAC79727 AAA67915 AAA61161 AAA40422 |
| AlphaFold | P10600 P17125 Q07258 |
Download HSQC peak lists in one of the following formats:
CSV: Backbone
or all simulated peaks
SPARKY: Backbone
or all simulated peaks