BMRB Entry 17471

Chem Shift validation: AVS_anomalous, AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR17471

NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
All files associated with the entry

Title:
Backbone 1H, 13C, and 15N Chemical Shift Assignments for p38 alpha MAPK
Deposition date:
2011-02-15
Original release date:
2011-12-12
Authors:
Francis, Dana; Peti, Wolfgang; Page, Rebecca
Citation:

Citation: Francis, Dana; Roycki, Bartosz; Koveal, Dorothy; Hummer, Gerhard; Page, Rebecca; Peti, Wolfgang. "Structural basis of p38 regulation by hematopoietic tyrosine phosphatase."  Nat. Chem. Biol. 7, 916-924 (2011).
PubMed: 22057126

Assembly members:

Assembly members:
p38_alpha, polymer, 352 residues, 40290 Da.

Natural source:

Natural source:   Common Name: human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pRPIB

Entity Sequences (FASTA):

Entity Sequences (FASTA):
p38_alpha: GHMGSQERPTFYRQELNKTI WEVPERYQNLSPVGSGAYGS VCAAFDTKTGLRVAVKKLSR PFQSIIHAKRTYRELRLLKH MKHENVIGLLDVFTPARSLE EFNDVYLVTHLMGADLNNIV KCQKLTDDHVQFLIYQILRG LKYIHSADIIHRDLKPSNLA VNEDCELKILDFGLARHTDD EMTGYVATRWYRAPEIMLNW MHYNQTVDIWSVGCIMAELL TGRTLFPGTDHIDQLKLILR LVGTPGAELLKKISSESARN YIQSLTQMPKMNFANVFIGA NPLAVDLLEKMLVLDSDKRI TAAQALAHAYFAQYHDPDDE PVADPYDQSFESRDLLIDEW KSLTYDEVISFV

Data sets:
Data typeCount
13C chemical shifts585
15N chemical shifts273
1H chemical shifts273

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1p38 alpha1

Entities:

Entity 1, p38 alpha 352 residues - 40290 Da.

Residues 1-3 are products of a non-native cloning artifact.

1   GLYHISMETGLYSERGLNGLUARGPROTHR
2   PHETYRARGGLNGLULEUASNLYSTHRILE
3   TRPGLUVALPROGLUARGTYRGLNASNLEU
4   SERPROVALGLYSERGLYALATYRGLYSER
5   VALCYSALAALAPHEASPTHRLYSTHRGLY
6   LEUARGVALALAVALLYSLYSLEUSERARG
7   PROPHEGLNSERILEILEHISALALYSARG
8   THRTYRARGGLULEUARGLEULEULYSHIS
9   METLYSHISGLUASNVALILEGLYLEULEU
10   ASPVALPHETHRPROALAARGSERLEUGLU
11   GLUPHEASNASPVALTYRLEUVALTHRHIS
12   LEUMETGLYALAASPLEUASNASNILEVAL
13   LYSCYSGLNLYSLEUTHRASPASPHISVAL
14   GLNPHELEUILETYRGLNILELEUARGGLY
15   LEULYSTYRILEHISSERALAASPILEILE
16   HISARGASPLEULYSPROSERASNLEUALA
17   VALASNGLUASPCYSGLULEULYSILELEU
18   ASPPHEGLYLEUALAARGHISTHRASPASP
19   GLUMETTHRGLYTYRVALALATHRARGTRP
20   TYRARGALAPROGLUILEMETLEUASNTRP
21   METHISTYRASNGLNTHRVALASPILETRP
22   SERVALGLYCYSILEMETALAGLULEULEU
23   THRGLYARGTHRLEUPHEPROGLYTHRASP
24   HISILEASPGLNLEULYSLEUILELEUARG
25   LEUVALGLYTHRPROGLYALAGLULEULEU
26   LYSLYSILESERSERGLUSERALAARGASN
27   TYRILEGLNSERLEUTHRGLNMETPROLYS
28   METASNPHEALAASNVALPHEILEGLYALA
29   ASNPROLEUALAVALASPLEULEUGLULYS
30   METLEUVALLEUASPSERASPLYSARGILE
31   THRALAALAGLNALALEUALAHISALATYR
32   PHEALAGLNTYRHISASPPROASPASPGLU
33   PROVALALAASPPROTYRASPGLNSERPHE
34   GLUSERARGASPLEULEUILEASPGLUTRP
35   LYSSERLEUTHRTYRASPGLUVALILESER
36   PHEVAL

Related Database Links:

BMRB 17940 19930 19934 19935 19936 19937
PDB 1A9U 1BL6 1BL7 1BMK 1DI9 1IAN 1KV1 1KV2 1LEW 1LEZ 1M7Q 1OUK 1OUY 1OVE 1OZ1 1P38 1R39 1R3C 1W7H 1W82 1W83 1W84 1WBN 1WBO 1WBS 1WBT 1WBV 1WBW 1WFC 1YQJ 1YW2 1YWR 1ZYJ 1ZZ2 1ZZL 2BAJ 2BAK 2BAL 2BAQ 2EWA 2FSL 2FSM 2FSO 2FST 2GFS 2GHL 2GHM 2GTM 2GTN 2I0H 2LGC 2NPQ 2OKR 2ONL 2OZA 2PUU 2QD9 2RG5 2RG6 2Y8O 2YIS 2YIW 2YIX 2ZAZ 2ZB0 2ZB1 3BV2 3BV3 3BX5 3C5U 3CTQ 3D7Z 3D83 3DS6 3DT1 3E92 3E93 3FC1 3FI4 3FKL 3FKN 3FKO 3FL4 3FLN 3FLQ 3FLS 3FLW 3FLY 3FLZ 3FMH 3FMJ 3FMK 3FML 3FMM 3FMN 3FSF 3FSK 3GC7 3GCP 3GCQ 3GCS 3GCU 3GCV 3GFE 3GI3 3HA8 3HEC 3HEG 3HL7 3HLL 3HP2 3HP5 3HRB 3HUB 3HUC 3HV3 3HV4 3HV5 3HV6 3HV7 3HVC 3IPH 3ITZ 3IW5 3IW6 3IW7 3IW8 3K3I 3K3J 3KF7 3KQ7 3L8S 3L8X 3LFA 3LFB 3LFC 3LFD 3LFE 3LFF 3LHJ 3MGY 3MH0 3MH1 3MH2 3MH3 3MPA 3MPT 3MVL 3MVM 3MW1 3NEW 3NNU 3NNV 3NNW 3NNX 3NWW 3O8P 3O8T 3O8U 3OBG 3OBJ 3OC1 3OCG 3OD6 3ODY 3ODZ 3OEF 3P4K 3P5K 3P78 3P79 3P7A 3P7B 3P7C 3PG3 3PY3 3QUD 3QUE 3RIN 3ROC 3S3I 3S4Q 3TG1 3U8W 3UVP 3UVQ 3UVR 3ZS5 3ZSG 3ZSH 3ZSI 3ZYA 4A9Y 4AA0 4AA4 4AA5 4AAC 4DLI 4DLJ 4E5A 4E5B 4E6A 4E6C 4E8A 4EH2 4EH3 4EH4 4EH5 4EH6 4EH7 4EH8 4EH9 4EHV 4EWQ 4F9W 4F9Y 4FA2 4GEO 4KA3 4KIN 4KIP 4KIQ 4L8M 4LOO 4LOP 4LOQ 4R3C 4TYH
DBJ BAB85654 BAE21782 BAE30324 BAE31659 BAF84398
EMBL CAG38743
GB AAA20888 AAA57456 AAA74301 AAB51285 AAC36131
PRF 2111247A 2124426A
REF NP_001003206 NP_001136366 NP_001161985 NP_001161986 NP_036081
SP O02812 P47811 P70618 Q16539
AlphaFold O02812 P47811 P70618 Q16539

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks