BMRB Entry 4081

Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR4081

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Title:
Sequence-specific 1H, 13C and 15N NMR Assignments of Recombinant Human Interferon Alpha-2a
Deposition date:
1997-12-15
Original release date:
1998-03-20
Authors:
Werner, Klaus; Grzesiek, Stephan; Labhardt, Alexander; Senn, Hans
Citation:

Citation: Werner, Klaus; Gsell, Bernard; Labhardt, Alexander; Wipf, Beat; Senn, Hans. "The Three-dimensional High Resolution Structure of Human Interferon alpha-2a Determined by Hetero-nuclear NMR Spectroscopy in Solution"  J. Mol. Biol. 274, 661-675 (1997).

Assembly members:

Assembly members:
Interferon_alpha-2a, polymer, 165 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli

Entity Sequences (FASTA):

Entity Sequences (FASTA):
Interferon_alpha-2a: CDLPQTHSLGSRRTLMLLAQ MRKISLFSCLKDRHDFGFPQ EEFGNQFQKAETIPVLHEMI QQIFNLFSTKDSSAAWDETL LDKFYTELYQQLNDLEACVI QGVGVTETPLMKEDSILAVR KYFQRITLYLKEKKYSPCAW EVVRAEIMRSFSLSTNLQES LRSKE

Data sets:
Data typeCount
13C chemical shifts724
15N chemical shifts172
1H chemical shifts1193

Additional metadata:

  • Assembly
  • Samples and Experiments
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  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1INF-alpha-2a1

Entities:

Entity 1, INF-alpha-2a 165 residues - Formula weight is not available

1   CYSASPLEUPROGLNTHRHISSERLEUGLY
2   SERARGARGTHRLEUMETLEULEUALAGLN
3   METARGLYSILESERLEUPHESERCYSLEU
4   LYSASPARGHISASPPHEGLYPHEPROGLN
5   GLUGLUPHEGLYASNGLNPHEGLNLYSALA
6   GLUTHRILEPROVALLEUHISGLUMETILE
7   GLNGLNILEPHEASNLEUPHESERTHRLYS
8   ASPSERSERALAALATRPASPGLUTHRLEU
9   LEUASPLYSPHETYRTHRGLULEUTYRGLN
10   GLNLEUASNASPLEUGLUALACYSVALILE
11   GLNGLYVALGLYVALTHRGLUTHRPROLEU
12   METLYSGLUASPSERILELEUALAVALARG
13   LYSTYRPHEGLNARGILETHRLEUTYRLEU
14   LYSGLULYSLYSTYRSERPROCYSALATRP
15   GLUVALVALARGALAGLUILEMETARGSER
16   PHESERLEUSERTHRASNLEUGLNGLUSER
17   LEUARGSERLYSGLU

Related Database Links:

BMRB 16677 18135 18344
PDB 1ITF 1RH2 2HYM 2KZ1 2LAG 2LMS 3S9D 3SE3 4YPG 4Z5R
DBJ BAJ20902
EMBL CAA23805 CAA23809 CAA23810 CAA25770 CAA46954
GB AAA52715 AAA59181 AAB59402 AAC64915 AAH74936
PRF 0611561A 0906342A
REF NP_000596 XP_003830724 XP_004047919 XP_528568
SP P01563
AlphaFold P01563

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