BMRB Entry 18250

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PDB ID: 2lpc
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS, SPARTA
BMRB Entry DOI: doi:10.13018/BMR18250
MolProbity Validation Chart

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Title:
NMR STRUCTURE of Bcl-XL
Deposition date:
2012-02-09
Original release date:
2012-03-12
Authors:
Wysoczanski, Piotr; Mart, Robert; Loveridge, Joel; Williams, Christopher; Whittaker, Sarah; Crump, Matthew; Allemann, Rudolf
Citation:

Citation: Wysoczanski, Piotr; Mart, Robert; Loveridge, E. Joel; Williams, Christopher; Whittaker, Sara B-M; Crump, Matthew; Allemann, Rudolf. "NMR Solution Structure of a Photoswitchable Apoptosis Activating Bak Peptide Bound to Bcl-x(L)."  J. Am. Chem. Soc. 134, 7644-7647 (2012).
PubMed: 22515821

Assembly members:

Assembly members:
BCL-XL, polymer, 185 residues, 21455.721 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: ESCHERICHIA COLI BL21(DE3)   Vector: pET19b

Entity Sequences (FASTA):

Entity Sequences (FASTA):
BCL-XL: MSQSNRELVVDFLSYKLSQK GYSWSQFSDVEENRTEAPEG TESEAVKQALREAGDEFELR YRRAFSDLTSQLHITPGTAY QSFEQVVNELFRDGVNWGRI VAFFSFGGALCVESVDKEMQ VLVSRIAAWMATYLNDHLEP WIQENGGWDTFVELYGNNAA AESRKGQERLEHHHHHHLEH HHHHH

Data sets:
Data typeCount
13C chemical shifts734
15N chemical shifts183
1H chemical shifts1116

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1BCL-XL1

Entities:

Entity 1, BCL-XL 185 residues - 21455.721 Da.

1   METSERGLNSERASNARGGLULEUVALVAL
2   ASPPHELEUSERTYRLYSLEUSERGLNLYS
3   GLYTYRSERTRPSERGLNPHESERASPVAL
4   GLUGLUASNARGTHRGLUALAPROGLUGLY
5   THRGLUSERGLUALAVALLYSGLNALALEU
6   ARGGLUALAGLYASPGLUPHEGLULEUARG
7   TYRARGARGALAPHESERASPLEUTHRSER
8   GLNLEUHISILETHRPROGLYTHRALATYR
9   GLNSERPHEGLUGLNVALVALASNGLULEU
10   PHEARGASPGLYVALASNTRPGLYARGILE
11   VALALAPHEPHESERPHEGLYGLYALALEU
12   CYSVALGLUSERVALASPLYSGLUMETGLN
13   VALLEUVALSERARGILEALAALATRPMET
14   ALATHRTYRLEUASNASPHISLEUGLUPRO
15   TRPILEGLNGLUASNGLYGLYTRPASPTHR
16   PHEVALGLULEUTYRGLYASNASNALAALA
17   ALAGLUSERARGLYSGLYGLNGLUARGLEU
18   GLUHISHISHISHISHISHISLEUGLUHIS
19   HISHISHISHISHIS

Related Database Links:

BMRB 18238 18792 18793
PDB 1G5J 1YSG 1YSI 1YSN 2LP8 2LPC 2M03 2M04 2O1Y 2PON 2YXJ 3PL7 3QKD 3SP7 3SPF 3WIZ 3ZK6 3ZLN 3ZLO 4EHR 4PPI 4QVE 4QVF
DBJ BAE87681

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