Aminoacyl-tRNA Biosynthesis
Description: Aminoacyl-tRNA (charged tRNA) is a transfer RNA that is connected to a specific amino acid that will be inserted into a polypeptide chain with a certain codon and anti-codon match. The synthesis of aminoacyl-tRNA is done in two major steps starting with an amino acid and the enzyme, aminoacyl-tRNA synthetase, is used. In the first step, the amino acid is combined with ATP to form aminoacyl-AMP. The second step invovles the aminoacyl-AMP group reacting with tRNA, and the AMP group leaves, and the tRNA is attached to the amino group. The overall reaction involves the hydrolysis of ATP, so it is a favorable reaction because it is exergonic.
Related BMRB Molecules
- L-Alanine
- L-Arginine
- L-Asparagine
- L-Aspartic Acid
- L-Cysteine
- L-Glutamic Acid
- L-Glutamine
- Glycine
- L-Histidine
- L-Isoleucine
- L-Leucine
- L-Lysine
- L-Methionine
- L-Phenylalanine
- L-Proline
- L-Serine
- O-Phospho-L-Serine
- L-Threonine
- L-Tryptophan
- L-Tyrosine
- L-Valine
For complete information about pathway, see KEGG [map00970]