HEADER DNA 04-JAN-04 1S0T TITLE SOLUTION STRUCTURE OF A DNA DUPLEX CONTAINING AN ALPHA- TITLE 2 ANOMERIC ADENOSINE: INSIGHTS INTO SUBSTRATE RECOGNITION BY TITLE 3 ENDONUCLEASE IV COMPND MOL_ID: 1; COMPND 2 MOLECULE: 5'-D(*GP*TP*CP*CP*(A3A)P*CP*GP*AP*CP*G)-3'; COMPND 3 CHAIN: A; COMPND 4 ENGINEERED: YES; COMPND 5 MOL_ID: 2; COMPND 6 MOLECULE: 5'-D(*CP*GP*TP*CP*GP*TP*GP*GP*AP*C)-3'; COMPND 7 CHAIN: B; COMPND 8 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 SYNTHETIC: YES; SOURCE 3 OTHER_DETAILS: THE CORE OF THE SEQUENCE CORRESPONDS TO THE SOURCE 4 RECOGNITION SITE OF E. COLI ENDONUCLEASE IV; SOURCE 5 MOL_ID: 2; SOURCE 6 SYNTHETIC: YES KEYWDS DNA DOUBLE HELIX WITH ENLARGED MINER GROOVE AND HELICAL KINK EXPDTA SOLUTION NMR MDLTYP MINIMIZED AVERAGE AUTHOR J.M.ARAMINI,S.H.CLEAVER,R.T.PON,R.P.CUNNINGHAM,M.W.GERMANN REVDAT 2 24-FEB-09 1S0T 1 VERSN REVDAT 1 20-APR-04 1S0T 0 JRNL AUTH J.M.ARAMINI,S.H.CLEAVER,R.T.PON,R.P.CUNNINGHAM, JRNL AUTH 2 M.W.GERMANN JRNL TITL SOLUTION STRUCTURE OF A DNA DUPLEX CONTAINING AN JRNL TITL 2 ALPHA-ANOMERIC ADENOSINE: INSIGHTS INTO SUBSTRATE JRNL TITL 3 RECOGNITION BY ENDONUCLEASE IV. JRNL REF J.MOL.BIOL. V. 338 77 2004 JRNL REFN ISSN 0022-2836 JRNL PMID 15050824 JRNL DOI 10.1016/J.JMB.2004.02.035 REMARK 1 REMARK 2 REMARK 2 RESOLUTION. NOT APPLICABLE. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : DYANA 1.5, AMBER 6.0 REMARK 3 AUTHORS : GUNTERT ET AL (DYANA), CASE ET AL. (AMBER) REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: THE STRUCTURE IS BASED ON A TOTAL OF REMARK 3 502 RESTRAINTS: 284 DISTANCE RESTRAINTS, 80 ENDOCYCLIC TORSION REMARK 3 ANGLE RESTRAINTS, 50 WATSON-CRICK DISTANCE AND ANGLE REMARK 3 RESTRAINTS, AND 88 BACKBONE TORSION ANGLE RESTRAINTS. THE REMARK 3 ALPHAA DUPLEX STRUCTURE WAS ELUCIDATED BY A COMBINATION OF REMARK 3 DYANA AND RMD/REM IN AMBER. ALL CALCULATIONS WERE PERFORMED IN REMARK 3 VACUO. THE FINAL STRUCTURE DEPOSITED HERE WAS OBTAINED BY REMARK 3 COORDINATE AVERAGING THE FINAL ENSEMBLE OF 10 RMD/REM REMARK 3 STRUCTURES FOLLOWED BY RESTRAINED ENERGY MINIMIZATION. REMARK 4 REMARK 4 1S0T COMPLIES WITH FORMAT V. 3.15, 01-DEC-08 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 12-JAN-04. REMARK 100 THE RCSB ID CODE IS RCSB021223. REMARK 210 REMARK 210 EXPERIMENTAL DETAILS REMARK 210 EXPERIMENT TYPE : NMR REMARK 210 TEMPERATURE (KELVIN) : 293; 283 REMARK 210 PH : 6.6; 6.6 REMARK 210 IONIC STRENGTH : 50 MM NACL; 50 MM NACL REMARK 210 PRESSURE : AMBIENT; AMBIENT REMARK 210 SAMPLE CONTENTS : 1.0 MM ALPHAA DUPLEX, 10 MM REMARK 210 PHOSPHATE BUFFER, 50 MM NACL, REMARK 210 0.1 MM EDTA, PH 6.6; 1.0 MM REMARK 210 ALPHAA DUPLEX, 10 MM PHOSPHATE REMARK 210 BUFFER, 50 MM NACL, 0.1 MM REMARK 210 EDTA, PH 6.6 REMARK 210 REMARK 210 NMR EXPERIMENTS CONDUCTED : 2D NOESY, DQF-COSY, 2D TOCSY, REMARK 210 2D 31P,1H CORRELATION, HSQC REMARK 210 SPECTROMETER FIELD STRENGTH : 600 MHZ, 500 MHZ REMARK 210 SPECTROMETER MODEL : AMX, AVANCE REMARK 210 SPECTROMETER MANUFACTURER : BRUKER REMARK 210 REMARK 210 STRUCTURE DETERMINATION. REMARK 210 SOFTWARE USED : MARDIGRAS 3.2, CORMA 5.2, REMARK 210 CURVES 5.1, MOLMOL 2.0 REMARK 210 METHOD USED : TORSION ANGLE DYNAMICS REMARK 210 MOLECULAR DYNAMICS REMARK 210 REMARK 210 CONFORMERS, NUMBER CALCULATED : 10 REMARK 210 CONFORMERS, NUMBER SUBMITTED : 1 REMARK 210 CONFORMERS, SELECTION CRITERIA : NULL REMARK 210 REMARK 210 BEST REPRESENTATIVE CONFORMER IN THIS ENSEMBLE : 1 REMARK 210 REMARK 210 REMARK: FOR NON-EXCHANGEABLE PROTONS, NOESY EXPERIMENTS IN D2O REMARK 210 WERE PERFORMED WITH 10S RELAXATION DELAYS AND MIXING TIMES OF REMARK 210 75MS, 150MS AND 250 MS. FOR EXCHANGEABLE PROTONS, A WATERGATE REMARK 210 NOESY WAS PERFORMED WITH A RELAXATION DELAY OF 4S AND 150MS REMARK 210 MIXING TIME. REMARK 215 REMARK 215 NMR STUDY REMARK 215 THE COORDINATES IN THIS ENTRY WERE GENERATED FROM SOLUTION REMARK 215 NMR DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE THAT REMARK 215 CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES ON REMARK 215 THESE RECORDS ARE MEANINGLESS. REMARK 470 REMARK 470 MISSING ATOM REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS(RES=RESIDUE NAME; REMARK 470 C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE): REMARK 470 RES CSSEQI ATOMS REMARK 470 A3A A 5 O1 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND ANGLES REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3 REMARK 500 DT A 2 C6 - C5 - C7 ANGL. DEV. = -4.3 DEGREES REMARK 500 DA A 8 O4' - C4' - C3' ANGL. DEV. = 3.9 DEGREES REMARK 500 DA A 8 N1 - C6 - N6 ANGL. DEV. = -4.4 DEGREES REMARK 500 DC A 9 N3 - C2 - O2 ANGL. DEV. = -4.2 DEGREES REMARK 500 DG A 10 O4' - C1' - N9 ANGL. DEV. = 2.8 DEGREES REMARK 500 DC B 11 O4' - C1' - N1 ANGL. DEV. = 5.7 DEGREES REMARK 500 DC B 14 N3 - C2 - O2 ANGL. DEV. = -4.5 DEGREES REMARK 500 DT B 16 O4' - C1' - N1 ANGL. DEV. = 2.3 DEGREES REMARK 500 DT B 16 C6 - C5 - C7 ANGL. DEV. = -4.5 DEGREES REMARK 500 DG B 17 O4' - C1' - N9 ANGL. DEV. = 3.0 DEGREES REMARK 500 DG B 18 O4' - C4' - C3' ANGL. DEV. = 4.9 DEGREES REMARK 500 DG B 18 O4' - C1' - N9 ANGL. DEV. = -4.6 DEGREES REMARK 500 DC B 20 O4' - C1' - N1 ANGL. DEV. = 2.2 DEGREES REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: PLANAR GROUPS REMARK 500 REMARK 500 PLANAR GROUPS IN THE FOLLOWING RESIDUES HAVE A TOTAL REMARK 500 RMS DISTANCE OF ALL ATOMS FROM THE BEST-FIT PLANE REMARK 500 BY MORE THAN AN EXPECTED VALUE OF 6*RMSD, WITH AN REMARK 500 RMSD 0.02 ANGSTROMS, OR AT LEAST ONE ATOM HAS REMARK 500 AN RMSD GREATER THAN THIS VALUE REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 M RES CSSEQI RMS TYPE REMARK 500 DG A 7 0.08 SIDE_CHAIN REMARK 500 DA A 8 0.08 SIDE_CHAIN REMARK 500 DT B 13 0.10 SIDE_CHAIN REMARK 500 DA B 19 0.06 SIDE_CHAIN REMARK 500 REMARK 500 REMARK: NULL REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 1S74 RELATED DB: PDB REMARK 900 RELATED ID: 1S75 RELATED DB: PDB DBREF 1S0T A 1 10 PDB 1S0T 1S0T 1 10 DBREF 1S0T B 11 20 PDB 1S0T 1S0T 11 20 SEQRES 1 A 10 DG DT DC DC A3A DC DG DA DC DG SEQRES 1 B 10 DC DG DT DC DG DT DG DG DA DC MODRES 1S0T A3A A 5 DA HET A3A A 5 32 HETNAM A3A 2'DEOXY-ALPHA-ANOMERIC-ADENOSINE-5'-PHOSPHATE FORMUL 1 A3A C10 H14 N5 O6 P LINK O3' DC A 4 P A3A A 5 1555 1555 1.62 LINK O3' A3A A 5 P DC A 6 1555 1555 1.62 CRYST1 1.000 1.000 1.000 90.00 90.00 90.00 P 1 1 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 1.000000 0.000000 0.000000 0.00000 SCALE2 0.000000 1.000000 0.000000 0.00000 SCALE3 0.000000 0.000000 1.000000 0.00000 ATOM 1 O5' DG A 1 -10.482 13.598 -1.130 1.00 10.00 O ATOM 2 C5' DG A 1 -10.592 14.338 -2.337 1.00 10.00 C ATOM 3 C4' DG A 1 -9.682 13.803 -3.456 1.00 10.00 C ATOM 4 O4' DG A 1 -8.325 14.136 -3.195 1.00 10.00 O ATOM 5 C3' DG A 1 -9.785 12.286 -3.648 1.00 10.00 C ATOM 6 O3' DG A 1 -9.845 11.998 -5.040 1.00 10.00 O ATOM 7 C2' DG A 1 -8.505 11.774 -2.992 1.00 10.00 C ATOM 8 C1' DG A 1 -7.549 12.964 -3.011 1.00 10.00 C ATOM 9 N9 DG A 1 -6.708 13.107 -1.810 1.00 10.00 N ATOM 10 C8 DG A 1 -7.134 13.261 -0.531 1.00 10.00 C ATOM 11 N7 DG A 1 -6.188 13.478 0.341 1.00 10.00 N ATOM 12 C5 DG A 1 -5.025 13.491 -0.437 1.00 10.00 C ATOM 13 C6 DG A 1 -3.647 13.747 -0.102 1.00 10.00 C ATOM 14 O6 DG A 1 -3.129 14.014 0.982 1.00 10.00 O ATOM 15 N1 DG A 1 -2.807 13.707 -1.200 1.00 10.00 N ATOM 16 C2 DG A 1 -3.223 13.456 -2.472 1.00 10.00 C ATOM 17 N2 DG A 1 -2.319 13.487 -3.419 1.00 10.00 N ATOM 18 N3 DG A 1 -4.485 13.205 -2.821 1.00 10.00 N ATOM 19 C4 DG A 1 -5.342 13.249 -1.760 1.00 10.00 C ATOM 20 H5' DG A 1 -10.337 15.383 -2.152 1.00 10.00 H ATOM 21 H5'' DG A 1 -11.626 14.291 -2.685 1.00 10.00 H ATOM 22 H4' DG A 1 -9.978 14.296 -4.384 1.00 10.00 H ATOM 23 H3' DG A 1 -10.669 11.887 -3.148 1.00 10.00 H ATOM 24 H2' DG A 1 -8.690 11.405 -1.989 1.00 10.00 H ATOM 25 H2'' DG A 1 -8.097 10.968 -3.568 1.00 10.00 H ATOM 26 H1' DG A 1 -6.869 12.838 -3.833 1.00 10.00 H ATOM 27 H8 DG A 1 -8.190 13.221 -0.353 1.00 10.00 H ATOM 28 H1 DG A 1 -1.831 13.916 -1.018 1.00 10.00 H ATOM 29 H21 DG A 1 -1.345 13.731 -3.207 1.00 10.00 H ATOM 30 H22 DG A 1 -2.631 13.256 -4.342 1.00 10.00 H ATOM 31 HO5' DG A 1 -11.082 13.967 -0.475 1.00 10.00 H ATOM 32 P DT A 2 -10.036 10.495 -5.625 1.00 10.00 P ATOM 33 OP1 DT A 2 -10.577 10.601 -6.998 1.00 10.00 O ATOM 34 OP2 DT A 2 -10.743 9.679 -4.613 1.00 10.00 O ATOM 35 O5' DT A 2 -8.516 9.958 -5.724 1.00 10.00 O ATOM 36 C5' DT A 2 -7.586 10.581 -6.586 1.00 10.00 C ATOM 37 C4' DT A 2 -6.163 10.068 -6.358 1.00 10.00 C ATOM 38 O4' DT A 2 -5.631 10.486 -5.117 1.00 10.00 O ATOM 39 C3' DT A 2 -5.987 8.548 -6.473 1.00 10.00 C ATOM 40 O3' DT A 2 -5.045 8.302 -7.508 1.00 10.00 O ATOM 41 C2' DT A 2 -5.453 8.181 -5.089 1.00 10.00 C ATOM 42 C1' DT A 2 -4.755 9.474 -4.661 1.00 10.00 C ATOM 43 N1 DT A 2 -4.510 9.669 -3.217 1.00 10.00 N ATOM 44 C2 DT A 2 -3.235 10.069 -2.802 1.00 10.00 C ATOM 45 O2 DT A 2 -2.279 10.187 -3.563 1.00 10.00 O ATOM 46 N3 DT A 2 -3.074 10.300 -1.455 1.00 10.00 N ATOM 47 C4 DT A 2 -4.040 10.129 -0.484 1.00 10.00 C ATOM 48 O4 DT A 2 -3.760 10.372 0.684 1.00 10.00 O ATOM 49 C5 DT A 2 -5.331 9.669 -0.990 1.00 10.00 C ATOM 50 C7 DT A 2 -6.474 9.380 -0.045 1.00 10.00 C ATOM 51 C6 DT A 2 -5.525 9.483 -2.319 1.00 10.00 C ATOM 52 H5' DT A 2 -7.593 11.659 -6.417 1.00 10.00 H ATOM 53 H5'' DT A 2 -7.875 10.389 -7.620 1.00 10.00 H ATOM 54 H4' DT A 2 -5.539 10.534 -7.104 1.00 10.00 H ATOM 55 H3' DT A 2 -6.932 8.042 -6.682 1.00 10.00 H ATOM 56 H2' DT A 2 -6.298 7.952 -4.440 1.00 10.00 H ATOM 57 H2'' DT A 2 -4.772 7.338 -5.127 1.00 10.00 H ATOM 58 H1' DT A 2 -3.792 9.514 -5.169 1.00 10.00 H ATOM 59 H3 DT A 2 -2.142 10.563 -1.145 1.00 10.00 H ATOM 60 H71 DT A 2 -6.833 10.312 0.387 1.00 10.00 H ATOM 61 H72 DT A 2 -6.119 8.729 0.755 1.00 10.00 H ATOM 62 H73 DT A 2 -7.281 8.878 -0.581 1.00 10.00 H ATOM 63 H6 DT A 2 -6.484 9.196 -2.712 1.00 10.00 H ATOM 64 P DC A 3 -4.623 6.821 -8.013 1.00 10.00 P ATOM 65 OP1 DC A 3 -4.746 6.784 -9.486 1.00 10.00 O ATOM 66 OP2 DC A 3 -5.320 5.808 -7.189 1.00 10.00 O ATOM 67 O5' DC A 3 -3.056 6.778 -7.631 1.00 10.00 O ATOM 68 C5' DC A 3 -2.118 7.600 -8.307 1.00 10.00 C ATOM 69 C4' DC A 3 -0.701 7.438 -7.745 1.00 10.00 C ATOM 70 O4' DC A 3 -0.692 7.853 -6.387 1.00 10.00 O ATOM 71 C3' DC A 3 -0.166 6.003 -7.813 1.00 10.00 C ATOM 72 O3' DC A 3 1.167 6.055 -8.297 1.00 10.00 O ATOM 73 C2' DC A 3 -0.278 5.542 -6.361 1.00 10.00 C ATOM 74 C1' DC A 3 -0.125 6.844 -5.568 1.00 10.00 C ATOM 75 N1 DC A 3 -0.850 6.844 -4.264 1.00 10.00 N ATOM 76 C2 DC A 3 -0.174 7.196 -3.088 1.00 10.00 C ATOM 77 O2 DC A 3 1.040 7.394 -3.080 1.00 10.00 O ATOM 78 N3 DC A 3 -0.851 7.306 -1.915 1.00 10.00 N ATOM 79 C4 DC A 3 -2.158 7.102 -1.901 1.00 10.00 C ATOM 80 N4 DC A 3 -2.782 7.183 -0.752 1.00 10.00 N ATOM 81 C5 DC A 3 -2.904 6.812 -3.080 1.00 10.00 C ATOM 82 C6 DC A 3 -2.209 6.655 -4.233 1.00 10.00 C ATOM 83 H5' DC A 3 -2.415 8.644 -8.203 1.00 10.00 H ATOM 84 H5'' DC A 3 -2.111 7.343 -9.368 1.00 10.00 H ATOM 85 H4' DC A 3 -0.037 8.090 -8.315 1.00 10.00 H ATOM 86 H3' DC A 3 -0.776 5.380 -8.470 1.00 10.00 H ATOM 87 H2' DC A 3 -1.260 5.095 -6.210 1.00 10.00 H ATOM 88 H2'' DC A 3 0.491 4.822 -6.101 1.00 10.00 H ATOM 89 H1' DC A 3 0.940 7.053 -5.417 1.00 10.00 H ATOM 90 H41 DC A 3 -2.233 7.377 0.091 1.00 10.00 H ATOM 91 H42 DC A 3 -3.747 6.940 -0.676 1.00 10.00 H ATOM 92 H5 DC A 3 -3.979 6.749 -3.081 1.00 10.00 H ATOM 93 H6 DC A 3 -2.716 6.409 -5.156 1.00 10.00 H ATOM 94 P DC A 4 2.087 4.742 -8.524 1.00 10.00 P ATOM 95 OP1 DC A 4 2.906 4.957 -9.736 1.00 10.00 O ATOM 96 OP2 DC A 4 1.247 3.530 -8.403 1.00 10.00 O ATOM 97 O5' DC A 4 3.057 4.811 -7.239 1.00 10.00 O ATOM 98 C5' DC A 4 3.978 5.878 -7.084 1.00 10.00 C ATOM 99 C4' DC A 4 4.699 5.793 -5.738 1.00 10.00 C ATOM 100 O4' DC A 4 3.729 5.838 -4.705 1.00 10.00 O ATOM 101 C3' DC A 4 5.530 4.516 -5.570 1.00 10.00 C ATOM 102 O3' DC A 4 6.851 4.844 -5.155 1.00 10.00 O ATOM 103 C2' DC A 4 4.778 3.760 -4.480 1.00 10.00 C ATOM 104 C1' DC A 4 4.021 4.858 -3.731 1.00 10.00 C ATOM 105 N1 DC A 4 2.725 4.398 -3.158 1.00 10.00 N ATOM 106 C2 DC A 4 2.436 4.674 -1.818 1.00 10.00 C ATOM 107 O2 DC A 4 3.290 5.122 -1.052 1.00 10.00 O ATOM 108 N3 DC A 4 1.197 4.417 -1.330 1.00 10.00 N ATOM 109 C4 DC A 4 0.290 3.841 -2.100 1.00 10.00 C ATOM 110 N4 DC A 4 -0.871 3.578 -1.551 1.00 10.00 N ATOM 111 C5 DC A 4 0.551 3.487 -3.458 1.00 10.00 C ATOM 112 C6 DC A 4 1.778 3.791 -3.951 1.00 10.00 C ATOM 113 H5' DC A 4 3.441 6.827 -7.130 1.00 10.00 H ATOM 114 H5'' DC A 4 4.711 5.850 -7.892 1.00 10.00 H ATOM 115 H4' DC A 4 5.358 6.657 -5.640 1.00 10.00 H ATOM 116 H3' DC A 4 5.553 3.942 -6.499 1.00 10.00 H ATOM 117 H2' DC A 4 4.112 3.003 -4.880 1.00 10.00 H ATOM 118 H2'' DC A 4 5.487 3.269 -3.843 1.00 10.00 H ATOM 119 H1' DC A 4 4.664 5.292 -2.957 1.00 10.00 H ATOM 120 H41 DC A 4 -1.040 3.933 -0.604 1.00 10.00 H ATOM 121 H42 DC A 4 -1.572 3.050 -2.030 1.00 10.00 H ATOM 122 H5 DC A 4 -0.187 3.011 -4.084 1.00 10.00 H ATOM 123 H6 DC A 4 2.024 3.572 -4.984 1.00 10.00 H HETATM 124 C8A A3A A 5 5.903 1.463 1.322 1.00 10.00 C HETATM 125 N9A A3A A 5 5.175 1.605 0.177 1.00 10.00 N HETATM 126 C4A A3A A 5 3.859 1.627 0.567 1.00 10.00 C HETATM 127 C5A A3A A 5 3.875 1.565 1.933 1.00 10.00 C HETATM 128 N7A A3A A 5 5.187 1.468 2.416 1.00 10.00 N HETATM 129 N3A A3A A 5 2.766 1.690 -0.240 1.00 10.00 N HETATM 130 C2A A3A A 5 1.634 1.668 0.464 1.00 10.00 C HETATM 131 N1A A3A A 5 1.483 1.626 1.788 1.00 10.00 N HETATM 132 C6A A3A A 5 2.598 1.586 2.535 1.00 10.00 C HETATM 133 N6A A3A A 5 2.427 1.540 3.844 1.00 10.00 N HETATM 134 P A3A A 5 8.057 3.757 -5.175 1.00 10.00 P HETATM 135 OP1 A3A A 5 9.333 4.493 -5.031 1.00 10.00 O HETATM 136 OP2 A3A A 5 7.855 2.863 -6.335 1.00 10.00 O HETATM 137 O6' A3A A 5 7.821 2.885 -3.832 1.00 10.00 O HETATM 138 C5' A3A A 5 8.362 3.272 -2.582 1.00 10.00 C HETATM 139 C4' A3A A 5 7.924 2.396 -1.411 1.00 10.00 C HETATM 140 O5' A3A A 5 6.695 2.912 -0.970 1.00 10.00 O HETATM 141 C3' A3A A 5 7.754 0.916 -1.767 1.00 10.00 C HETATM 142 O3' A3A A 5 8.171 0.100 -0.697 1.00 10.00 O HETATM 143 C2' A3A A 5 6.253 0.801 -1.985 1.00 10.00 C HETATM 144 C1' A3A A 5 5.689 1.952 -1.155 1.00 10.00 C HETATM 145 H8A A3A A 5 6.982 1.389 1.263 1.00 10.00 H HETATM 146 H2A A3A A 5 0.727 1.648 -0.122 1.00 10.00 H HETATM 147 HN61 A3A A 5 1.477 1.491 4.212 1.00 10.00 H HETATM 148 HN62 A3A A 5 3.236 1.452 4.432 1.00 10.00 H HETATM 149 H5' A3A A 5 8.127 4.316 -2.371 1.00 10.00 H HETATM 150 H5'' A3A A 5 9.421 3.158 -2.644 1.00 10.00 H HETATM 151 H4' A3A A 5 8.630 2.480 -0.580 1.00 10.00 H HETATM 152 H3' A3A A 5 8.313 0.662 -2.671 1.00 10.00 H HETATM 153 H2' A3A A 5 6.020 0.954 -3.038 1.00 10.00 H HETATM 154 H2'' A3A A 5 5.873 -0.161 -1.652 1.00 10.00 H HETATM 155 H1' A3A A 5 4.910 2.435 -1.700 1.00 10.00 H ATOM 156 P DC A 6 8.677 -1.414 -0.940 1.00 10.00 P ATOM 157 OP1 DC A 6 10.125 -1.380 -1.236 1.00 10.00 O ATOM 158 OP2 DC A 6 7.739 -2.088 -1.863 1.00 10.00 O ATOM 159 O5' DC A 6 8.456 -2.038 0.521 1.00 10.00 O ATOM 160 C5' DC A 6 9.053 -1.464 1.660 1.00 10.00 C ATOM 161 C4' DC A 6 8.160 -1.601 2.890 1.00 10.00 C ATOM 162 O4' DC A 6 6.913 -1.016 2.623 1.00 10.00 O ATOM 163 C3' DC A 6 7.954 -3.059 3.326 1.00 10.00 C ATOM 164 O3' DC A 6 8.440 -3.206 4.651 1.00 10.00 O ATOM 165 C2' DC A 6 6.453 -3.247 3.236 1.00 10.00 C ATOM 166 C1' DC A 6 5.874 -1.860 3.065 1.00 10.00 C ATOM 167 N1 DC A 6 4.810 -1.857 2.046 1.00 10.00 N ATOM 168 C2 DC A 6 3.482 -1.702 2.427 1.00 10.00 C ATOM 169 O2 DC A 6 3.149 -1.660 3.610 1.00 10.00 O ATOM 170 N3 DC A 6 2.528 -1.584 1.476 1.00 10.00 N ATOM 171 C4 DC A 6 2.864 -1.670 0.200 1.00 10.00 C ATOM 172 N4 DC A 6 1.899 -1.442 -0.655 1.00 10.00 N ATOM 173 C5 DC A 6 4.205 -1.902 -0.235 1.00 10.00 C ATOM 174 C6 DC A 6 5.152 -1.994 0.732 1.00 10.00 C ATOM 175 H5' DC A 6 9.250 -0.403 1.499 1.00 10.00 H ATOM 176 H5'' DC A 6 9.974 -1.995 1.830 1.00 10.00 H ATOM 177 H4' DC A 6 8.587 -1.005 3.684 1.00 10.00 H ATOM 178 H3' DC A 6 8.420 -3.774 2.645 1.00 10.00 H ATOM 179 H2' DC A 6 6.269 -3.798 2.314 1.00 10.00 H ATOM 180 H2'' DC A 6 6.026 -3.730 4.111 1.00 10.00 H ATOM 181 H1' DC A 6 5.489 -1.526 4.023 1.00 10.00 H ATOM 182 H41 DC A 6 0.968 -1.256 -0.279 1.00 10.00 H ATOM 183 H42 DC A 6 2.105 -1.293 -1.614 1.00 10.00 H ATOM 184 H5 DC A 6 4.465 -2.019 -1.274 1.00 10.00 H ATOM 185 H6 DC A 6 6.210 -2.168 0.561 1.00 10.00 H ATOM 186 P DG A 7 8.734 -4.650 5.322 1.00 10.00 P ATOM 187 OP1 DG A 7 9.577 -4.431 6.518 1.00 10.00 O ATOM 188 OP2 DG A 7 9.196 -5.570 4.260 1.00 10.00 O ATOM 189 O5' DG A 7 7.288 -5.160 5.817 1.00 10.00 O ATOM 190 C5' DG A 7 6.646 -4.623 6.961 1.00 10.00 C ATOM 191 C4' DG A 7 5.303 -5.323 7.215 1.00 10.00 C ATOM 192 O4' DG A 7 4.391 -5.020 6.173 1.00 10.00 O ATOM 193 C3' DG A 7 5.410 -6.850 7.301 1.00 10.00 C ATOM 194 O3' DG A 7 4.550 -7.273 8.349 1.00 10.00 O ATOM 195 C2' DG A 7 4.988 -7.256 5.899 1.00 10.00 C ATOM 196 C1' DG A 7 3.901 -6.223 5.610 1.00 10.00 C ATOM 197 N9 DG A 7 3.644 -5.969 4.176 1.00 10.00 N ATOM 198 C8 DG A 7 4.547 -5.932 3.145 1.00 10.00 C ATOM 199 N7 DG A 7 4.058 -5.493 2.019 1.00 10.00 N ATOM 200 C5 DG A 7 2.702 -5.298 2.302 1.00 10.00 C ATOM 201 C6 DG A 7 1.607 -4.896 1.464 1.00 10.00 C ATOM 202 O6 DG A 7 1.609 -4.540 0.291 1.00 10.00 O ATOM 203 N1 DG A 7 0.379 -4.973 2.092 1.00 10.00 N ATOM 204 C2 DG A 7 0.211 -5.323 3.396 1.00 10.00 C ATOM 205 N2 DG A 7 -1.025 -5.423 3.826 1.00 10.00 N ATOM 206 N3 DG A 7 1.210 -5.636 4.228 1.00 10.00 N ATOM 207 C4 DG A 7 2.434 -5.625 3.615 1.00 10.00 C ATOM 208 H5' DG A 7 6.473 -3.556 6.818 1.00 10.00 H ATOM 209 H5'' DG A 7 7.288 -4.764 7.832 1.00 10.00 H ATOM 210 H4' DG A 7 4.870 -4.950 8.140 1.00 10.00 H ATOM 211 H3' DG A 7 6.417 -7.210 7.483 1.00 10.00 H ATOM 212 H2' DG A 7 5.834 -7.129 5.229 1.00 10.00 H ATOM 213 H2'' DG A 7 4.657 -8.283 5.863 1.00 10.00 H ATOM 214 H1' DG A 7 2.983 -6.524 6.117 1.00 10.00 H ATOM 215 H8 DG A 7 5.588 -6.200 3.283 1.00 10.00 H ATOM 216 H1 DG A 7 -0.436 -4.837 1.499 1.00 10.00 H ATOM 217 H21 DG A 7 -1.821 -5.291 3.192 1.00 10.00 H ATOM 218 H22 DG A 7 -1.142 -5.729 4.771 1.00 10.00 H ATOM 219 P DA A 8 4.279 -8.818 8.725 1.00 10.00 P ATOM 220 OP1 DA A 8 4.126 -8.921 10.192 1.00 10.00 O ATOM 221 OP2 DA A 8 5.258 -9.675 8.019 1.00 10.00 O ATOM 222 O5' DA A 8 2.837 -9.028 8.044 1.00 10.00 O ATOM 223 C5' DA A 8 1.672 -8.415 8.576 1.00 10.00 C ATOM 224 C4' DA A 8 0.461 -8.817 7.734 1.00 10.00 C ATOM 225 O4' DA A 8 0.601 -8.294 6.424 1.00 10.00 O ATOM 226 C3' DA A 8 0.287 -10.330 7.674 1.00 10.00 C ATOM 227 O3' DA A 8 -1.029 -10.649 8.098 1.00 10.00 O ATOM 228 C2' DA A 8 0.549 -10.581 6.204 1.00 10.00 C ATOM 229 C1' DA A 8 0.191 -9.279 5.506 1.00 10.00 C ATOM 230 N9 DA A 8 0.957 -9.120 4.261 1.00 10.00 N ATOM 231 C8 DA A 8 2.307 -9.234 4.124 1.00 10.00 C ATOM 232 N7 DA A 8 2.770 -8.888 2.954 1.00 10.00 N ATOM 233 C5 DA A 8 1.600 -8.569 2.247 1.00 10.00 C ATOM 234 C6 DA A 8 1.319 -8.104 0.941 1.00 10.00 C ATOM 235 N6 DA A 8 2.220 -7.736 0.045 1.00 10.00 N ATOM 236 N1 DA A 8 0.055 -7.938 0.547 1.00 10.00 N ATOM 237 C2 DA A 8 -0.923 -8.208 1.399 1.00 10.00 C ATOM 238 N3 DA A 8 -0.816 -8.611 2.661 1.00 10.00 N ATOM 239 C4 DA A 8 0.486 -8.766 3.024 1.00 10.00 C ATOM 240 H5' DA A 8 1.780 -7.330 8.565 1.00 10.00 H ATOM 241 H5'' DA A 8 1.521 -8.747 9.604 1.00 10.00 H ATOM 242 H4' DA A 8 -0.459 -8.426 8.145 1.00 10.00 H ATOM 243 H3' DA A 8 1.026 -10.850 8.286 1.00 10.00 H ATOM 244 H2' DA A 8 1.596 -10.852 6.082 1.00 10.00 H ATOM 245 H2'' DA A 8 -0.074 -11.351 5.827 1.00 10.00 H ATOM 246 H1' DA A 8 -0.884 -9.216 5.309 1.00 10.00 H ATOM 247 H8 DA A 8 2.880 -9.574 4.971 1.00 10.00 H ATOM 248 H61 DA A 8 1.890 -7.315 -0.824 1.00 10.00 H ATOM 249 H62 DA A 8 3.196 -7.755 0.289 1.00 10.00 H ATOM 250 H2 DA A 8 -1.916 -8.072 1.005 1.00 10.00 H ATOM 251 P DC A 9 -1.596 -12.162 8.159 1.00 10.00 P ATOM 252 OP1 DC A 9 -2.681 -12.210 9.162 1.00 10.00 O ATOM 253 OP2 DC A 9 -0.455 -13.099 8.252 1.00 10.00 O ATOM 254 O5' DC A 9 -2.251 -12.311 6.696 1.00 10.00 O ATOM 255 C5' DC A 9 -3.329 -11.487 6.293 1.00 10.00 C ATOM 256 C4' DC A 9 -3.748 -11.807 4.858 1.00 10.00 C ATOM 257 O4' DC A 9 -2.764 -11.402 3.921 1.00 10.00 O ATOM 258 C3' DC A 9 -4.089 -13.273 4.631 1.00 10.00 C ATOM 259 O3' DC A 9 -5.360 -13.351 4.004 1.00 10.00 O ATOM 260 C2' DC A 9 -2.934 -13.679 3.743 1.00 10.00 C ATOM 261 C1' DC A 9 -2.616 -12.415 2.947 1.00 10.00 C ATOM 262 N1 DC A 9 -1.268 -12.252 2.334 1.00 10.00 N ATOM 263 C2 DC A 9 -1.182 -11.648 1.072 1.00 10.00 C ATOM 264 O2 DC A 9 -2.183 -11.369 0.414 1.00 10.00 O ATOM 265 N3 DC A 9 0.026 -11.361 0.531 1.00 10.00 N ATOM 266 C4 DC A 9 1.121 -11.640 1.213 1.00 10.00 C ATOM 267 N4 DC A 9 2.248 -11.297 0.646 1.00 10.00 N ATOM 268 C5 DC A 9 1.099 -12.213 2.519 1.00 10.00 C ATOM 269 C6 DC A 9 -0.120 -12.518 3.039 1.00 10.00 C ATOM 270 H5' DC A 9 -3.037 -10.438 6.350 1.00 10.00 H ATOM 271 H5'' DC A 9 -4.178 -11.656 6.958 1.00 10.00 H ATOM 272 H4' DC A 9 -4.635 -11.260 4.626 1.00 10.00 H ATOM 273 H3' DC A 9 -4.080 -13.850 5.556 1.00 10.00 H ATOM 274 H2' DC A 9 -2.124 -13.885 4.410 1.00 10.00 H ATOM 275 H2'' DC A 9 -3.199 -14.541 3.153 1.00 10.00 H ATOM 276 H1' DC A 9 -3.363 -12.337 2.159 1.00 10.00 H ATOM 277 H41 DC A 9 2.182 -10.870 -0.283 1.00 10.00 H ATOM 278 H42 DC A 9 3.121 -11.418 1.119 1.00 10.00 H ATOM 279 H5 DC A 9 2.011 -12.401 3.065 1.00 10.00 H ATOM 280 H6 DC A 9 -0.220 -12.953 4.020 1.00 10.00 H ATOM 281 P DG A 10 -6.079 -14.755 3.660 1.00 10.00 P ATOM 282 OP1 DG A 10 -7.535 -14.516 3.554 1.00 10.00 O ATOM 283 OP2 DG A 10 -5.562 -15.793 4.578 1.00 10.00 O ATOM 284 O5' DG A 10 -5.500 -15.046 2.188 1.00 10.00 O ATOM 285 C5' DG A 10 -5.989 -14.355 1.053 1.00 10.00 C ATOM 286 C4' DG A 10 -5.132 -14.644 -0.181 1.00 10.00 C ATOM 287 O4' DG A 10 -3.863 -14.024 -0.089 1.00 10.00 O ATOM 288 C3' DG A 10 -4.847 -16.133 -0.417 1.00 10.00 C ATOM 289 O3' DG A 10 -5.780 -16.682 -1.329 1.00 10.00 O ATOM 290 C2' DG A 10 -3.437 -16.118 -1.006 1.00 10.00 C ATOM 291 C1' DG A 10 -3.062 -14.633 -1.082 1.00 10.00 C ATOM 292 N9 DG A 10 -1.630 -14.462 -0.785 1.00 10.00 N ATOM 293 C8 DG A 10 -0.964 -14.844 0.346 1.00 10.00 C ATOM 294 N7 DG A 10 0.332 -14.722 0.275 1.00 10.00 N ATOM 295 C5 DG A 10 0.544 -14.215 -1.014 1.00 10.00 C ATOM 296 C6 DG A 10 1.748 -13.889 -1.729 1.00 10.00 C ATOM 297 O6 DG A 10 2.925 -13.956 -1.374 1.00 10.00 O ATOM 298 N1 DG A 10 1.508 -13.458 -3.020 1.00 10.00 N ATOM 299 C2 DG A 10 0.271 -13.320 -3.569 1.00 10.00 C ATOM 300 N2 DG A 10 0.207 -12.878 -4.803 1.00 10.00 N ATOM 301 N3 DG A 10 -0.867 -13.608 -2.941 1.00 10.00 N ATOM 302 C4 DG A 10 -0.662 -14.050 -1.665 1.00 10.00 C ATOM 303 H5' DG A 10 -5.982 -13.281 1.242 1.00 10.00 H ATOM 304 H5'' DG A 10 -7.013 -14.674 0.858 1.00 10.00 H ATOM 305 H4' DG A 10 -5.644 -14.247 -1.060 1.00 10.00 H ATOM 306 H3' DG A 10 -4.835 -16.686 0.531 1.00 10.00 H ATOM 307 HO3' DG A 10 -5.652 -17.634 -1.389 1.00 10.00 H ATOM 308 H2' DG A 10 -2.770 -16.633 -0.309 1.00 10.00 H ATOM 309 H2'' DG A 10 -3.392 -16.579 -1.994 1.00 10.00 H ATOM 310 H1' DG A 10 -3.277 -14.210 -2.072 1.00 10.00 H ATOM 311 H8 DG A 10 -1.510 -15.228 1.195 1.00 10.00 H ATOM 312 H1 DG A 10 2.327 -13.227 -3.571 1.00 10.00 H ATOM 313 H21 DG A 10 1.056 -12.752 -5.366 1.00 10.00 H ATOM 314 H22 DG A 10 -0.714 -12.737 -5.175 1.00 10.00 H TER 315 DG A 10 ATOM 316 O5' DC B 11 7.362 -9.502 -8.239 1.00 10.00 O ATOM 317 C5' DC B 11 7.184 -10.159 -9.486 1.00 10.00 C ATOM 318 C4' DC B 11 5.779 -10.769 -9.625 1.00 10.00 C ATOM 319 O4' DC B 11 5.630 -11.868 -8.735 1.00 10.00 O ATOM 320 C3' DC B 11 4.662 -9.754 -9.354 1.00 10.00 C ATOM 321 O3' DC B 11 3.685 -9.833 -10.381 1.00 10.00 O ATOM 322 C2' DC B 11 4.133 -10.207 -8.015 1.00 10.00 C ATOM 323 C1' DC B 11 4.497 -11.652 -7.913 1.00 10.00 C ATOM 324 N1 DC B 11 4.696 -12.037 -6.504 1.00 10.00 N ATOM 325 C2 DC B 11 3.661 -12.577 -5.744 1.00 10.00 C ATOM 326 O2 DC B 11 2.546 -12.767 -6.225 1.00 10.00 O ATOM 327 N3 DC B 11 3.880 -12.878 -4.439 1.00 10.00 N ATOM 328 C4 DC B 11 5.055 -12.600 -3.895 1.00 10.00 C ATOM 329 N4 DC B 11 5.198 -12.919 -2.632 1.00 10.00 N ATOM 330 C5 DC B 11 6.115 -11.970 -4.619 1.00 10.00 C ATOM 331 C6 DC B 11 5.870 -11.699 -5.926 1.00 10.00 C ATOM 332 H5' DC B 11 7.923 -10.955 -9.590 1.00 10.00 H ATOM 333 H5'' DC B 11 7.331 -9.439 -10.293 1.00 10.00 H ATOM 334 H4' DC B 11 5.659 -11.152 -10.637 1.00 10.00 H ATOM 335 H3' DC B 11 5.024 -8.733 -9.237 1.00 10.00 H ATOM 336 H2' DC B 11 4.632 -9.653 -7.214 1.00 10.00 H ATOM 337 H2'' DC B 11 3.056 -10.209 -8.028 1.00 10.00 H ATOM 338 H1' DC B 11 3.646 -12.157 -8.287 1.00 10.00 H ATOM 339 H41 DC B 11 4.374 -13.319 -2.173 1.00 10.00 H ATOM 340 H42 DC B 11 6.047 -12.720 -2.141 1.00 10.00 H ATOM 341 H5 DC B 11 7.056 -11.697 -4.169 1.00 10.00 H ATOM 342 H6 DC B 11 6.507 -11.198 -6.631 1.00 10.00 H ATOM 343 HO5' DC B 11 8.236 -9.098 -8.208 1.00 10.00 H ATOM 344 P DG B 12 2.689 -8.603 -10.720 1.00 10.00 P ATOM 345 OP1 DG B 12 2.223 -8.776 -12.114 1.00 10.00 O ATOM 346 OP2 DG B 12 3.350 -7.338 -10.329 1.00 10.00 O ATOM 347 O5' DG B 12 1.428 -8.809 -9.735 1.00 10.00 O ATOM 348 C5' DG B 12 0.352 -9.672 -10.060 1.00 10.00 C ATOM 349 C4' DG B 12 -0.863 -9.375 -9.172 1.00 10.00 C ATOM 350 O4' DG B 12 -0.623 -9.850 -7.858 1.00 10.00 O ATOM 351 C3' DG B 12 -1.224 -7.885 -9.107 1.00 10.00 C ATOM 352 O3' DG B 12 -2.629 -7.774 -9.299 1.00 10.00 O ATOM 353 C2' DG B 12 -0.716 -7.524 -7.730 1.00 10.00 C ATOM 354 C1' DG B 12 -0.849 -8.809 -6.931 1.00 10.00 C ATOM 355 N9 DG B 12 0.157 -8.944 -5.856 1.00 10.00 N ATOM 356 C8 DG B 12 1.508 -8.714 -5.917 1.00 10.00 C ATOM 357 N7 DG B 12 2.154 -9.034 -4.831 1.00 10.00 N ATOM 358 C5 DG B 12 1.151 -9.489 -3.967 1.00 10.00 C ATOM 359 C6 DG B 12 1.202 -9.978 -2.616 1.00 10.00 C ATOM 360 O6 DG B 12 2.173 -10.176 -1.891 1.00 10.00 O ATOM 361 N1 DG B 12 -0.046 -10.261 -2.089 1.00 10.00 N ATOM 362 C2 DG B 12 -1.201 -10.210 -2.808 1.00 10.00 C ATOM 363 N2 DG B 12 -2.308 -10.567 -2.204 1.00 10.00 N ATOM 364 N3 DG B 12 -1.287 -9.793 -4.073 1.00 10.00 N ATOM 365 C4 DG B 12 -0.076 -9.430 -4.592 1.00 10.00 C ATOM 366 H5' DG B 12 0.661 -10.710 -9.933 1.00 10.00 H ATOM 367 H5'' DG B 12 0.056 -9.512 -11.098 1.00 10.00 H ATOM 368 H4' DG B 12 -1.729 -9.910 -9.551 1.00 10.00 H ATOM 369 H3' DG B 12 -0.686 -7.267 -9.826 1.00 10.00 H ATOM 370 H2' DG B 12 0.328 -7.228 -7.828 1.00 10.00 H ATOM 371 H2'' DG B 12 -1.321 -6.740 -7.315 1.00 10.00 H ATOM 372 H1' DG B 12 -1.859 -8.859 -6.516 1.00 10.00 H ATOM 373 H8 DG B 12 1.987 -8.316 -6.803 1.00 10.00 H ATOM 374 H1 DG B 12 -0.080 -10.532 -1.109 1.00 10.00 H ATOM 375 H21 DG B 12 -2.299 -10.869 -1.223 1.00 10.00 H ATOM 376 H22 DG B 12 -3.150 -10.497 -2.739 1.00 10.00 H ATOM 377 P DT B 13 -3.486 -6.416 -9.074 1.00 10.00 P ATOM 378 OP1 DT B 13 -4.655 -6.449 -9.979 1.00 10.00 O ATOM 379 OP2 DT B 13 -2.572 -5.252 -9.082 1.00 10.00 O ATOM 380 O5' DT B 13 -4.006 -6.649 -7.565 1.00 10.00 O ATOM 381 C5' DT B 13 -4.821 -7.767 -7.253 1.00 10.00 C ATOM 382 C4' DT B 13 -5.109 -7.858 -5.755 1.00 10.00 C ATOM 383 O4' DT B 13 -3.892 -7.943 -5.035 1.00 10.00 O ATOM 384 C3' DT B 13 -5.897 -6.665 -5.203 1.00 10.00 C ATOM 385 O3' DT B 13 -7.007 -7.198 -4.496 1.00 10.00 O ATOM 386 C2' DT B 13 -4.892 -5.978 -4.277 1.00 10.00 C ATOM 387 C1' DT B 13 -3.993 -7.137 -3.876 1.00 10.00 C ATOM 388 N1 DT B 13 -2.635 -6.731 -3.440 1.00 10.00 N ATOM 389 C2 DT B 13 -2.218 -7.131 -2.171 1.00 10.00 C ATOM 390 O2 DT B 13 -2.970 -7.604 -1.326 1.00 10.00 O ATOM 391 N3 DT B 13 -0.882 -6.974 -1.897 1.00 10.00 N ATOM 392 C4 DT B 13 0.064 -6.407 -2.717 1.00 10.00 C ATOM 393 O4 DT B 13 1.232 -6.405 -2.339 1.00 10.00 O ATOM 394 C5 DT B 13 -0.469 -5.869 -3.970 1.00 10.00 C ATOM 395 C7 DT B 13 0.442 -5.098 -4.914 1.00 10.00 C ATOM 396 C6 DT B 13 -1.779 -6.064 -4.292 1.00 10.00 C ATOM 397 H5' DT B 13 -4.312 -8.682 -7.558 1.00 10.00 H ATOM 398 H5'' DT B 13 -5.763 -7.694 -7.798 1.00 10.00 H ATOM 399 H4' DT B 13 -5.682 -8.770 -5.577 1.00 10.00 H ATOM 400 H3' DT B 13 -6.230 -5.995 -5.998 1.00 10.00 H ATOM 401 H2' DT B 13 -4.333 -5.197 -4.793 1.00 10.00 H ATOM 402 H2'' DT B 13 -5.383 -5.565 -3.411 1.00 10.00 H ATOM 403 H1' DT B 13 -4.495 -7.685 -3.074 1.00 10.00 H ATOM 404 H3 DT B 13 -0.560 -7.308 -0.997 1.00 10.00 H ATOM 405 H71 DT B 13 1.189 -5.767 -5.336 1.00 10.00 H ATOM 406 H72 DT B 13 0.969 -4.326 -4.353 1.00 10.00 H ATOM 407 H73 DT B 13 -0.117 -4.622 -5.720 1.00 10.00 H ATOM 408 H6 DT B 13 -2.188 -5.721 -5.230 1.00 10.00 H ATOM 409 P DC B 14 -8.133 -6.274 -3.797 1.00 10.00 P ATOM 410 OP1 DC B 14 -9.384 -7.058 -3.712 1.00 10.00 O ATOM 411 OP2 DC B 14 -8.133 -4.951 -4.460 1.00 10.00 O ATOM 412 O5' DC B 14 -7.554 -6.078 -2.304 1.00 10.00 O ATOM 413 C5' DC B 14 -7.531 -7.136 -1.362 1.00 10.00 C ATOM 414 C4' DC B 14 -7.128 -6.625 0.028 1.00 10.00 C ATOM 415 O4' DC B 14 -5.739 -6.325 0.067 1.00 10.00 O ATOM 416 C3' DC B 14 -7.887 -5.352 0.418 1.00 10.00 C ATOM 417 O3' DC B 14 -8.343 -5.490 1.754 1.00 10.00 O ATOM 418 C2' DC B 14 -6.816 -4.275 0.245 1.00 10.00 C ATOM 419 C1' DC B 14 -5.535 -5.033 0.613 1.00 10.00 C ATOM 420 N1 DC B 14 -4.222 -4.531 0.099 1.00 10.00 N ATOM 421 C2 DC B 14 -3.074 -4.738 0.887 1.00 10.00 C ATOM 422 O2 DC B 14 -3.136 -5.177 2.035 1.00 10.00 O ATOM 423 N3 DC B 14 -1.843 -4.438 0.399 1.00 10.00 N ATOM 424 C4 DC B 14 -1.737 -3.913 -0.808 1.00 10.00 C ATOM 425 N4 DC B 14 -0.527 -3.675 -1.244 1.00 10.00 N ATOM 426 C5 DC B 14 -2.862 -3.660 -1.644 1.00 10.00 C ATOM 427 C6 DC B 14 -4.085 -3.987 -1.159 1.00 10.00 C ATOM 428 H5' DC B 14 -6.829 -7.907 -1.683 1.00 10.00 H ATOM 429 H5'' DC B 14 -8.528 -7.572 -1.292 1.00 10.00 H ATOM 430 H4' DC B 14 -7.336 -7.409 0.758 1.00 10.00 H ATOM 431 H3' DC B 14 -8.737 -5.170 -0.242 1.00 10.00 H ATOM 432 H2' DC B 14 -6.806 -3.927 -0.783 1.00 10.00 H ATOM 433 H2'' DC B 14 -7.019 -3.444 0.904 1.00 10.00 H ATOM 434 H1' DC B 14 -5.489 -5.078 1.707 1.00 10.00 H ATOM 435 H41 DC B 14 0.254 -3.956 -0.641 1.00 10.00 H ATOM 436 H42 DC B 14 -0.380 -3.217 -2.118 1.00 10.00 H ATOM 437 H5 DC B 14 -2.767 -3.228 -2.625 1.00 10.00 H ATOM 438 H6 DC B 14 -4.943 -3.829 -1.792 1.00 10.00 H ATOM 439 P DG B 15 -9.216 -4.353 2.506 1.00 10.00 P ATOM 440 OP1 DG B 15 -10.185 -5.028 3.396 1.00 10.00 O ATOM 441 OP2 DG B 15 -9.691 -3.366 1.510 1.00 10.00 O ATOM 442 O5' DG B 15 -8.087 -3.649 3.416 1.00 10.00 O ATOM 443 C5' DG B 15 -7.573 -4.305 4.560 1.00 10.00 C ATOM 444 C4' DG B 15 -6.476 -3.484 5.238 1.00 10.00 C ATOM 445 O4' DG B 15 -5.310 -3.437 4.423 1.00 10.00 O ATOM 446 C3' DG B 15 -6.893 -2.044 5.574 1.00 10.00 C ATOM 447 O3' DG B 15 -6.823 -1.865 6.979 1.00 10.00 O ATOM 448 C2' DG B 15 -5.924 -1.243 4.741 1.00 10.00 C ATOM 449 C1' DG B 15 -4.726 -2.150 4.513 1.00 10.00 C ATOM 450 N9 DG B 15 -4.012 -1.840 3.251 1.00 10.00 N ATOM 451 C8 DG B 15 -4.541 -1.547 2.022 1.00 10.00 C ATOM 452 N7 DG B 15 -3.668 -1.300 1.092 1.00 10.00 N ATOM 453 C5 DG B 15 -2.447 -1.419 1.757 1.00 10.00 C ATOM 454 C6 DG B 15 -1.100 -1.233 1.299 1.00 10.00 C ATOM 455 O6 DG B 15 -0.680 -0.906 0.192 1.00 10.00 O ATOM 456 N1 DG B 15 -0.161 -1.463 2.281 1.00 10.00 N ATOM 457 C2 DG B 15 -0.461 -1.826 3.558 1.00 10.00 C ATOM 458 N2 DG B 15 0.541 -2.037 4.375 1.00 10.00 N ATOM 459 N3 DG B 15 -1.698 -1.976 4.033 1.00 10.00 N ATOM 460 C4 DG B 15 -2.651 -1.763 3.079 1.00 10.00 C ATOM 461 H5' DG B 15 -7.162 -5.274 4.273 1.00 10.00 H ATOM 462 H5'' DG B 15 -8.383 -4.465 5.273 1.00 10.00 H ATOM 463 H4' DG B 15 -6.206 -3.989 6.167 1.00 10.00 H ATOM 464 H3' DG B 15 -7.874 -1.763 5.185 1.00 10.00 H ATOM 465 H2' DG B 15 -6.453 -1.083 3.809 1.00 10.00 H ATOM 466 H2'' DG B 15 -5.646 -0.320 5.234 1.00 10.00 H ATOM 467 H1' DG B 15 -4.037 -2.058 5.354 1.00 10.00 H ATOM 468 H8 DG B 15 -5.597 -1.524 1.843 1.00 10.00 H ATOM 469 H1 DG B 15 0.810 -1.390 1.989 1.00 10.00 H ATOM 470 H21 DG B 15 1.514 -1.892 4.085 1.00 10.00 H ATOM 471 H22 DG B 15 0.298 -2.323 5.303 1.00 10.00 H ATOM 472 P DT B 16 -7.134 -0.461 7.719 1.00 10.00 P ATOM 473 OP1 DT B 16 -7.612 -0.751 9.088 1.00 10.00 O ATOM 474 OP2 DT B 16 -7.934 0.396 6.816 1.00 10.00 O ATOM 475 O5' DT B 16 -5.652 0.153 7.817 1.00 10.00 O ATOM 476 C5' DT B 16 -4.635 -0.523 8.533 1.00 10.00 C ATOM 477 C4' DT B 16 -3.282 0.138 8.277 1.00 10.00 C ATOM 478 O4' DT B 16 -2.984 0.096 6.890 1.00 10.00 O ATOM 479 C3' DT B 16 -3.226 1.602 8.731 1.00 10.00 C ATOM 480 O3' DT B 16 -2.187 1.754 9.684 1.00 10.00 O ATOM 481 C2' DT B 16 -2.972 2.355 7.424 1.00 10.00 C ATOM 482 C1' DT B 16 -2.302 1.288 6.556 1.00 10.00 C ATOM 483 N1 DT B 16 -2.363 1.533 5.083 1.00 10.00 N ATOM 484 C2 DT B 16 -1.163 1.496 4.366 1.00 10.00 C ATOM 485 O2 DT B 16 -0.071 1.344 4.902 1.00 10.00 O ATOM 486 N3 DT B 16 -1.237 1.652 2.997 1.00 10.00 N ATOM 487 C4 DT B 16 -2.394 1.893 2.279 1.00 10.00 C ATOM 488 O4 DT B 16 -2.320 1.976 1.058 1.00 10.00 O ATOM 489 C5 DT B 16 -3.606 2.001 3.095 1.00 10.00 C ATOM 490 C7 DT B 16 -4.947 2.366 2.470 1.00 10.00 C ATOM 491 C6 DT B 16 -3.552 1.805 4.440 1.00 10.00 C ATOM 492 H5' DT B 16 -4.578 -1.560 8.203 1.00 10.00 H ATOM 493 H5'' DT B 16 -4.860 -0.502 9.600 1.00 10.00 H ATOM 494 H4' DT B 16 -2.516 -0.424 8.815 1.00 10.00 H ATOM 495 H3' DT B 16 -4.179 1.910 9.167 1.00 10.00 H ATOM 496 H2' DT B 16 -3.929 2.668 7.012 1.00 10.00 H ATOM 497 H2'' DT B 16 -2.324 3.216 7.565 1.00 10.00 H ATOM 498 H1' DT B 16 -1.258 1.195 6.873 1.00 10.00 H ATOM 499 H3 DT B 16 -0.363 1.614 2.480 1.00 10.00 H ATOM 500 H71 DT B 16 -4.806 2.676 1.435 1.00 10.00 H ATOM 501 H72 DT B 16 -5.394 3.192 3.023 1.00 10.00 H ATOM 502 H73 DT B 16 -5.638 1.525 2.493 1.00 10.00 H ATOM 503 H6 DT B 16 -4.456 1.880 5.019 1.00 10.00 H ATOM 504 P DG B 17 -1.955 3.132 10.500 1.00 10.00 P ATOM 505 OP1 DG B 17 -1.347 2.799 11.807 1.00 10.00 O ATOM 506 OP2 DG B 17 -3.196 3.936 10.446 1.00 10.00 O ATOM 507 O5' DG B 17 -0.846 3.867 9.595 1.00 10.00 O ATOM 508 C5' DG B 17 0.493 3.409 9.569 1.00 10.00 C ATOM 509 C4' DG B 17 1.313 4.192 8.544 1.00 10.00 C ATOM 510 O4' DG B 17 0.860 3.884 7.232 1.00 10.00 O ATOM 511 C3' DG B 17 1.246 5.712 8.731 1.00 10.00 C ATOM 512 O3' DG B 17 2.573 6.203 8.854 1.00 10.00 O ATOM 513 C2' DG B 17 0.558 6.170 7.449 1.00 10.00 C ATOM 514 C1' DG B 17 0.912 5.067 6.461 1.00 10.00 C ATOM 515 N9 DG B 17 0.005 4.990 5.296 1.00 10.00 N ATOM 516 C8 DG B 17 -1.365 4.883 5.240 1.00 10.00 C ATOM 517 N7 DG B 17 -1.846 4.818 4.031 1.00 10.00 N ATOM 518 C5 DG B 17 -0.713 4.909 3.216 1.00 10.00 C ATOM 519 C6 DG B 17 -0.556 4.896 1.788 1.00 10.00 C ATOM 520 O6 DG B 17 -1.397 4.811 0.898 1.00 10.00 O ATOM 521 N1 DG B 17 0.761 4.987 1.388 1.00 10.00 N ATOM 522 C2 DG B 17 1.819 5.080 2.234 1.00 10.00 C ATOM 523 N2 DG B 17 3.010 5.151 1.690 1.00 10.00 N ATOM 524 N3 DG B 17 1.718 5.108 3.560 1.00 10.00 N ATOM 525 C4 DG B 17 0.423 5.012 3.990 1.00 10.00 C ATOM 526 H5' DG B 17 0.517 2.351 9.306 1.00 10.00 H ATOM 527 H5'' DG B 17 0.936 3.539 10.557 1.00 10.00 H ATOM 528 H4' DG B 17 2.355 3.895 8.638 1.00 10.00 H ATOM 529 H3' DG B 17 0.658 5.986 9.610 1.00 10.00 H ATOM 530 H2' DG B 17 -0.520 6.220 7.609 1.00 10.00 H ATOM 531 H2'' DG B 17 0.952 7.119 7.115 1.00 10.00 H ATOM 532 H1' DG B 17 1.924 5.240 6.079 1.00 10.00 H ATOM 533 H8 DG B 17 -2.000 4.837 6.112 1.00 10.00 H ATOM 534 H1 DG B 17 0.934 4.913 0.392 1.00 10.00 H ATOM 535 H21 DG B 17 3.131 5.161 0.671 1.00 10.00 H ATOM 536 H22 DG B 17 3.780 5.244 2.324 1.00 10.00 H ATOM 537 P DG B 18 2.919 7.756 9.160 1.00 10.00 P ATOM 538 OP1 DG B 18 4.029 7.796 10.136 1.00 10.00 O ATOM 539 OP2 DG B 18 1.662 8.483 9.444 1.00 10.00 O ATOM 540 O5' DG B 18 3.477 8.267 7.735 1.00 10.00 O ATOM 541 C5' DG B 18 4.721 7.811 7.229 1.00 10.00 C ATOM 542 C4' DG B 18 5.058 8.516 5.914 1.00 10.00 C ATOM 543 O4' DG B 18 4.173 8.131 4.895 1.00 10.00 O ATOM 544 C3' DG B 18 5.146 10.036 6.013 1.00 10.00 C ATOM 545 O3' DG B 18 6.427 10.388 5.486 1.00 10.00 O ATOM 546 C2' DG B 18 3.971 10.439 5.140 1.00 10.00 C ATOM 547 C1' DG B 18 3.793 9.274 4.172 1.00 10.00 C ATOM 548 N9 DG B 18 2.397 9.008 3.828 1.00 10.00 N ATOM 549 C8 DG B 18 1.386 8.825 4.718 1.00 10.00 C ATOM 550 N7 DG B 18 0.233 8.550 4.172 1.00 10.00 N ATOM 551 C5 DG B 18 0.536 8.474 2.803 1.00 10.00 C ATOM 552 C6 DG B 18 -0.269 8.160 1.655 1.00 10.00 C ATOM 553 O6 DG B 18 -1.474 7.942 1.577 1.00 10.00 O ATOM 554 N1 DG B 18 0.457 8.081 0.479 1.00 10.00 N ATOM 555 C2 DG B 18 1.803 8.261 0.400 1.00 10.00 C ATOM 556 N2 DG B 18 2.370 8.079 -0.767 1.00 10.00 N ATOM 557 N3 DG B 18 2.578 8.599 1.430 1.00 10.00 N ATOM 558 C4 DG B 18 1.883 8.690 2.601 1.00 10.00 C ATOM 559 H5' DG B 18 4.673 6.735 7.057 1.00 10.00 H ATOM 560 H5'' DG B 18 5.508 8.021 7.954 1.00 10.00 H ATOM 561 H4' DG B 18 6.005 8.198 5.539 1.00 10.00 H ATOM 562 H3' DG B 18 5.030 10.400 7.035 1.00 10.00 H ATOM 563 H2' DG B 18 3.069 10.653 5.730 1.00 10.00 H ATOM 564 H2'' DG B 18 4.277 11.290 4.587 1.00 10.00 H ATOM 565 H1' DG B 18 4.396 9.449 3.275 1.00 10.00 H ATOM 566 H8 DG B 18 1.639 8.903 5.770 1.00 10.00 H ATOM 567 H1 DG B 18 -0.054 7.879 -0.374 1.00 10.00 H ATOM 568 H21 DG B 18 1.842 7.810 -1.603 1.00 10.00 H ATOM 569 H22 DG B 18 3.366 8.178 -0.785 1.00 10.00 H ATOM 570 P DA B 19 6.894 11.889 5.085 1.00 10.00 P ATOM 571 OP1 DA B 19 8.367 11.961 5.205 1.00 10.00 O ATOM 572 OP2 DA B 19 6.045 12.864 5.804 1.00 10.00 O ATOM 573 O5' DA B 19 6.510 11.941 3.513 1.00 10.00 O ATOM 574 C5' DA B 19 7.163 11.114 2.559 1.00 10.00 C ATOM 575 C4' DA B 19 6.604 11.350 1.149 1.00 10.00 C ATOM 576 O4' DA B 19 5.243 10.945 1.094 1.00 10.00 O ATOM 577 C3' DA B 19 6.716 12.807 0.701 1.00 10.00 C ATOM 578 O3' DA B 19 7.392 12.861 -0.545 1.00 10.00 O ATOM 579 C2' DA B 19 5.254 13.196 0.631 1.00 10.00 C ATOM 580 C1' DA B 19 4.514 11.893 0.343 1.00 10.00 C ATOM 581 N9 DA B 19 3.141 11.960 0.871 1.00 10.00 N ATOM 582 C8 DA B 19 2.815 12.321 2.140 1.00 10.00 C ATOM 583 N7 DA B 19 1.559 12.196 2.453 1.00 10.00 N ATOM 584 C5 DA B 19 1.001 11.751 1.249 1.00 10.00 C ATOM 585 C6 DA B 19 -0.306 11.406 0.848 1.00 10.00 C ATOM 586 N6 DA B 19 -1.343 11.378 1.666 1.00 10.00 N ATOM 587 N1 DA B 19 -0.549 11.026 -0.410 1.00 10.00 N ATOM 588 C2 DA B 19 0.466 10.982 -1.264 1.00 10.00 C ATOM 589 N3 DA B 19 1.744 11.273 -1.033 1.00 10.00 N ATOM 590 C4 DA B 19 1.949 11.645 0.262 1.00 10.00 C ATOM 591 H5' DA B 19 7.022 10.066 2.825 1.00 10.00 H ATOM 592 H5'' DA B 19 8.231 11.338 2.560 1.00 10.00 H ATOM 593 H4' DA B 19 7.150 10.759 0.422 1.00 10.00 H ATOM 594 H3' DA B 19 7.223 13.424 1.444 1.00 10.00 H ATOM 595 H2' DA B 19 4.989 13.633 1.590 1.00 10.00 H ATOM 596 H2'' DA B 19 5.047 13.903 -0.133 1.00 10.00 H ATOM 597 H1' DA B 19 4.523 11.652 -0.724 1.00 10.00 H ATOM 598 H8 DA B 19 3.611 12.672 2.769 1.00 10.00 H ATOM 599 H61 DA B 19 -2.236 11.029 1.311 1.00 10.00 H ATOM 600 H62 DA B 19 -1.209 11.606 2.635 1.00 10.00 H ATOM 601 H2 DA B 19 0.207 10.638 -2.255 1.00 10.00 H ATOM 602 P DC B 20 8.010 14.235 -1.135 1.00 10.00 P ATOM 603 OP1 DC B 20 9.021 13.884 -2.157 1.00 10.00 O ATOM 604 OP2 DC B 20 8.379 15.116 -0.006 1.00 10.00 O ATOM 605 O5' DC B 20 6.737 14.876 -1.876 1.00 10.00 O ATOM 606 C5' DC B 20 6.309 14.406 -3.141 1.00 10.00 C ATOM 607 C4' DC B 20 4.910 14.930 -3.463 1.00 10.00 C ATOM 608 O4' DC B 20 3.966 14.393 -2.557 1.00 10.00 O ATOM 609 C3' DC B 20 4.755 16.450 -3.345 1.00 10.00 C ATOM 610 O3' DC B 20 4.977 17.082 -4.592 1.00 10.00 O ATOM 611 C2' DC B 20 3.310 16.628 -2.881 1.00 10.00 C ATOM 612 C1' DC B 20 2.810 15.194 -2.664 1.00 10.00 C ATOM 613 N1 DC B 20 1.965 15.050 -1.455 1.00 10.00 N ATOM 614 C2 DC B 20 0.640 14.629 -1.593 1.00 10.00 C ATOM 615 O2 DC B 20 0.175 14.326 -2.690 1.00 10.00 O ATOM 616 N3 DC B 20 -0.169 14.567 -0.507 1.00 10.00 N ATOM 617 C4 DC B 20 0.312 14.901 0.678 1.00 10.00 C ATOM 618 N4 DC B 20 -0.530 14.799 1.676 1.00 10.00 N ATOM 619 C5 DC B 20 1.667 15.320 0.875 1.00 10.00 C ATOM 620 C6 DC B 20 2.463 15.381 -0.224 1.00 10.00 C ATOM 621 H5' DC B 20 6.281 13.315 -3.139 1.00 10.00 H ATOM 622 H5'' DC B 20 7.009 14.743 -3.907 1.00 10.00 H ATOM 623 H4' DC B 20 4.650 14.627 -4.479 1.00 10.00 H ATOM 624 H3' DC B 20 5.421 16.836 -2.571 1.00 10.00 H ATOM 625 HO3' DC B 20 4.939 18.037 -4.483 1.00 10.00 H ATOM 626 H2' DC B 20 3.304 17.195 -1.949 1.00 10.00 H ATOM 627 H2'' DC B 20 2.699 17.129 -3.633 1.00 10.00 H ATOM 628 H1' DC B 20 2.242 14.881 -3.537 1.00 10.00 H ATOM 629 H41 DC B 20 -1.468 14.463 1.436 1.00 10.00 H ATOM 630 H42 DC B 20 -0.235 14.955 2.620 1.00 10.00 H ATOM 631 H5 DC B 20 2.053 15.582 1.848 1.00 10.00 H ATOM 632 H6 DC B 20 3.501 15.695 -0.199 1.00 10.00 H TER 633 DC B 20 CONECT 102 134 CONECT 124 125 128 145 CONECT 125 124 126 144 CONECT 126 125 127 129 CONECT 127 126 128 132 CONECT 128 124 127 CONECT 129 126 130 CONECT 130 129 131 146 CONECT 131 130 132 CONECT 132 127 131 133 CONECT 133 132 147 148 CONECT 134 102 135 136 137 CONECT 135 134 CONECT 136 134 CONECT 137 134 138 CONECT 138 137 139 149 150 CONECT 139 138 140 141 151 CONECT 140 139 144 CONECT 141 139 142 143 152 CONECT 142 141 156 CONECT 143 141 144 153 154 CONECT 144 125 140 143 155 CONECT 145 124 CONECT 146 130 CONECT 147 133 CONECT 148 133 CONECT 149 138 CONECT 150 138 CONECT 151 139 CONECT 152 141 CONECT 153 143 CONECT 154 143 CONECT 155 144 CONECT 156 142 MASTER 125 0 1 0 0 0 0 6 631 2 34 2 END