USER MOD reduce.3.24.130724 H: found=0, std=0, add=190, rem=0, adj=12 USER MOD reduce.3.24.130724 removed 191 hydrogens (90 hets) HEADER RNA/DNA 30-JAN-03 1NTS TITLE 5'(DCCPUPCPCPUPUP)3':3'(RAGGAGGAAA)5', WHERE P=PROPYNYL COMPND MOL_ID: 1; COMPND 2 MOLECULE: 5'-R(*AP*AP*AP*GP*GP*AP*GP*GP*A)-3'; COMPND 3 CHAIN: A; COMPND 4 ENGINEERED: YES; COMPND 5 MOL_ID: 2; COMPND 6 MOLECULE: 5'-D(*(5PC)P*(5PC)P*(PDU)P*(5PC)P*(5PC)P*(PDU) COMPND 7 P*(PDU))-3'; COMPND 8 CHAIN: B; COMPND 9 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 SYNTHETIC: YES; SOURCE 3 MOL_ID: 2; SOURCE 4 SYNTHETIC: YES KEYWDS DNA, RNA, HYBRID, PROPYNYL, RNA/DNA COMPLEX EXPDTA SOLUTION NMR MDLTYP MINIMIZED AVERAGE AUTHOR B.M.ZNOSKO,T.W.BARNES III,T.R.KRUGH,D.H.TURNER REVDAT 2 24-FEB-09 1NTS 1 VERSN REVDAT 1 10-JUN-03 1NTS 0 JRNL AUTH B.M.ZNOSKO,T.W.BARNES III,T.R.KRUGH,D.H.TURNER JRNL TITL NMR STUDIES OF DNA SINGLE STRANDS AND DNA:RNA JRNL TITL 2 HYBRIDS WITH AND WITHOUT 1-PROPYNYLATION AT C5 OF JRNL TITL 3 OLIGOPYRIMIDINES JRNL REF J.AM.CHEM.SOC. V. 125 6090 2003 JRNL REFN ISSN 0002-7863 JRNL PMID 12785839 JRNL DOI 10.1021/JA021285D REMARK 1 REMARK 1 REFERENCE 1 REMARK 1 AUTH T.W.BARNES III,D.H.TURNER REMARK 1 TITL LONG-RANGE COOPERATIVITY IN MOLECULAR RECOGNITION REMARK 1 TITL 2 OF RNA BY OLIGODEOXYNUCLEOTIDES WITH MULTIPLE REMARK 1 TITL 3 C5-(1-PROPYNYL) PYRIMIDINES REMARK 1 REF J.AM.CHEM.SOC. V. 123 4107 2001 REMARK 1 REFN ISSN 0002-7863 REMARK 1 DOI 10.1021/JA003208T REMARK 2 REMARK 2 RESOLUTION. NOT APPLICABLE. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : DISCOVER 95.0 REMARK 3 AUTHORS : MSI REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: THE STRUCTURE IS BASED ON A TOTAL OF REMARK 3 149 INTERPROTON DISTANCE RESTRAINTS, 18 HYDROGEN BOND REMARK 3 RESTRAINTS, AND 59 DIHEDRAL ANGLE RESTRAINTS. REMARK 4 REMARK 4 1NTS COMPLIES WITH FORMAT V. 3.15, 01-DEC-08 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 13-MAR-03. REMARK 100 THE RCSB ID CODE IS RCSB018195. REMARK 210 REMARK 210 EXPERIMENTAL DETAILS REMARK 210 EXPERIMENT TYPE : NMR REMARK 210 TEMPERATURE (KELVIN) : 273; 303 REMARK 210 PH : 7.0; 7.0 REMARK 210 IONIC STRENGTH : 80 MM NACL; 80 MM NACL REMARK 210 PRESSURE : AMBIENT; AMBIENT REMARK 210 SAMPLE CONTENTS : ~1MM HYBRID, 80 MM NACL, 10 REMARK 210 MM PHOSPHATE BUFFER, 0.5 MM REMARK 210 EDTA, 90% H2O, 10% D2O; ~2.5 REMARK 210 MM HYBRID, 80 MM NACL, 10 MM REMARK 210 PHOSPHATE, 0.5 MM EDTA, REMARK 210 99.996% D2O REMARK 210 REMARK 210 NMR EXPERIMENTS CONDUCTED : 2D NOESY REMARK 210 SPECTROMETER FIELD STRENGTH : 500 MHZ REMARK 210 SPECTROMETER MODEL : INOVA REMARK 210 SPECTROMETER MANUFACTURER : VARIAN REMARK 210 REMARK 210 STRUCTURE DETERMINATION. REMARK 210 SOFTWARE USED : VNMR 5.2, FELIX 2000, REMARK 210 DISCOVER 95.0 REMARK 210 METHOD USED : SIMULATED ANNEALING, ENERGY REMARK 210 MINIMIZATION REMARK 210 REMARK 210 CONFORMERS, NUMBER CALCULATED : NULL REMARK 210 CONFORMERS, NUMBER SUBMITTED : 1 REMARK 210 CONFORMERS, SELECTION CRITERIA : NULL REMARK 210 REMARK 210 BEST REPRESENTATIVE CONFORMER IN THIS ENSEMBLE : 1 REMARK 210 REMARK 210 REMARK: NULL REMARK 215 REMARK 215 NMR STUDY REMARK 215 THE COORDINATES IN THIS ENTRY WERE GENERATED FROM SOLUTION REMARK 215 NMR DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE THAT REMARK 215 CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES ON REMARK 215 THESE RECORDS ARE MEANINGLESS. REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND LENGTHS REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,2(A3,1X,A1,I4,A1,1X,A4,3X),1X,F6.3) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 RES CSSEQI ATM2 DEVIATION REMARK 500 A A 2 N3 A A 2 C4 0.121 REMARK 500 A A 2 C4 A A 2 C5 0.078 REMARK 500 A A 2 N7 A A 2 C8 0.067 REMARK 500 A A 3 N3 A A 3 C4 0.120 REMARK 500 A A 3 C4 A A 3 C5 0.076 REMARK 500 A A 3 N7 A A 3 C8 0.067 REMARK 500 A A 4 N3 A A 4 C4 0.122 REMARK 500 A A 4 C4 A A 4 C5 0.076 REMARK 500 A A 4 N7 A A 4 C8 0.067 REMARK 500 G A 5 N1 G A 5 C2 0.093 REMARK 500 G A 5 N3 G A 5 C4 0.096 REMARK 500 G A 5 C4 G A 5 C5 0.057 REMARK 500 G A 5 C5 G A 5 C6 0.133 REMARK 500 G A 5 N7 G A 5 C8 0.072 REMARK 500 G A 6 N1 G A 6 C2 0.093 REMARK 500 G A 6 N3 G A 6 C4 0.095 REMARK 500 G A 6 C4 G A 6 C5 0.057 REMARK 500 G A 6 C5 G A 6 C6 0.132 REMARK 500 G A 6 N7 G A 6 C8 0.071 REMARK 500 A A 7 N3 A A 7 C4 0.122 REMARK 500 A A 7 C4 A A 7 C5 0.076 REMARK 500 A A 7 N7 A A 7 C8 0.067 REMARK 500 G A 8 N1 G A 8 C2 0.093 REMARK 500 G A 8 N3 G A 8 C4 0.097 REMARK 500 G A 8 C4 G A 8 C5 0.057 REMARK 500 G A 8 C5 G A 8 C6 0.131 REMARK 500 G A 8 N7 G A 8 C8 0.072 REMARK 500 G A 9 N1 G A 9 C2 0.093 REMARK 500 G A 9 N3 G A 9 C4 0.096 REMARK 500 G A 9 C4 G A 9 C5 0.055 REMARK 500 G A 9 C5 G A 9 C6 0.130 REMARK 500 G A 9 N7 G A 9 C8 0.071 REMARK 500 A A 10 N3 A A 10 C4 0.122 REMARK 500 A A 10 C4 A A 10 C5 0.076 REMARK 500 A A 10 N7 A A 10 C8 0.067 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND ANGLES REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3 REMARK 500 A A 2 C2 - N3 - C4 ANGL. DEV. = 5.2 DEGREES REMARK 500 A A 2 N3 - C4 - C5 ANGL. DEV. = -9.4 DEGREES REMARK 500 A A 2 C5 - N7 - C8 ANGL. DEV. = -6.4 DEGREES REMARK 500 A A 2 N7 - C8 - N9 ANGL. DEV. = 8.6 DEGREES REMARK 500 A A 2 C8 - N9 - C4 ANGL. DEV. = -6.4 DEGREES REMARK 500 A A 2 N3 - C4 - N9 ANGL. DEV. = 7.0 DEGREES REMARK 500 A A 3 OP1 - P - OP2 ANGL. DEV. = -9.6 DEGREES REMARK 500 A A 3 C2 - N3 - C4 ANGL. DEV. = 5.0 DEGREES REMARK 500 A A 3 N3 - C4 - C5 ANGL. DEV. = -9.1 DEGREES REMARK 500 A A 3 C5 - N7 - C8 ANGL. DEV. = -6.5 DEGREES REMARK 500 A A 3 N7 - C8 - N9 ANGL. DEV. = 8.4 DEGREES REMARK 500 A A 3 C8 - N9 - C4 ANGL. DEV. = -6.0 DEGREES REMARK 500 A A 3 N3 - C4 - N9 ANGL. DEV. = 6.8 DEGREES REMARK 500 A A 4 OP1 - P - OP2 ANGL. DEV. = -10.1 DEGREES REMARK 500 A A 4 C2 - N3 - C4 ANGL. DEV. = 5.2 DEGREES REMARK 500 A A 4 N3 - C4 - C5 ANGL. DEV. = -9.3 DEGREES REMARK 500 A A 4 C5 - N7 - C8 ANGL. DEV. = -6.4 DEGREES REMARK 500 A A 4 N7 - C8 - N9 ANGL. DEV. = 8.4 DEGREES REMARK 500 A A 4 C8 - N9 - C4 ANGL. DEV. = -6.1 DEGREES REMARK 500 A A 4 N3 - C4 - N9 ANGL. DEV. = 7.0 DEGREES REMARK 500 G A 5 OP1 - P - OP2 ANGL. DEV. = -10.0 DEGREES REMARK 500 G A 5 C2 - N3 - C4 ANGL. DEV. = 11.2 DEGREES REMARK 500 G A 5 N3 - C4 - C5 ANGL. DEV. = -10.9 DEGREES REMARK 500 G A 5 C5 - C6 - N1 ANGL. DEV. = 3.6 DEGREES REMARK 500 G A 5 C4 - C5 - N7 ANGL. DEV. = 2.5 DEGREES REMARK 500 G A 5 C5 - N7 - C8 ANGL. DEV. = -7.1 DEGREES REMARK 500 G A 5 N7 - C8 - N9 ANGL. DEV. = 8.7 DEGREES REMARK 500 G A 5 C8 - N9 - C4 ANGL. DEV. = -6.9 DEGREES REMARK 500 G A 5 N9 - C4 - C5 ANGL. DEV. = 2.8 DEGREES REMARK 500 G A 5 N3 - C4 - N9 ANGL. DEV. = 8.1 DEGREES REMARK 500 G A 5 C5 - C6 - O6 ANGL. DEV. = -4.7 DEGREES REMARK 500 G A 6 OP1 - P - OP2 ANGL. DEV. = -10.1 DEGREES REMARK 500 G A 6 C2 - N3 - C4 ANGL. DEV. = 11.2 DEGREES REMARK 500 G A 6 N3 - C4 - C5 ANGL. DEV. = -10.9 DEGREES REMARK 500 G A 6 C5 - C6 - N1 ANGL. DEV. = 3.6 DEGREES REMARK 500 G A 6 C4 - C5 - N7 ANGL. DEV. = 2.5 DEGREES REMARK 500 G A 6 C5 - N7 - C8 ANGL. DEV. = -7.1 DEGREES REMARK 500 G A 6 N7 - C8 - N9 ANGL. DEV. = 8.7 DEGREES REMARK 500 G A 6 C8 - N9 - C4 ANGL. DEV. = -6.9 DEGREES REMARK 500 G A 6 N9 - C4 - C5 ANGL. DEV. = 2.8 DEGREES REMARK 500 G A 6 N3 - C4 - N9 ANGL. DEV. = 8.1 DEGREES REMARK 500 G A 6 C5 - C6 - O6 ANGL. DEV. = -4.9 DEGREES REMARK 500 A A 7 OP1 - P - OP2 ANGL. DEV. = -10.1 DEGREES REMARK 500 A A 7 C2 - N3 - C4 ANGL. DEV. = 5.1 DEGREES REMARK 500 A A 7 N3 - C4 - C5 ANGL. DEV. = -9.3 DEGREES REMARK 500 A A 7 C5 - N7 - C8 ANGL. DEV. = -6.4 DEGREES REMARK 500 A A 7 N7 - C8 - N9 ANGL. DEV. = 8.4 DEGREES REMARK 500 A A 7 C8 - N9 - C4 ANGL. DEV. = -6.2 DEGREES REMARK 500 A A 7 N3 - C4 - N9 ANGL. DEV. = 7.0 DEGREES REMARK 500 G A 8 OP1 - P - OP2 ANGL. DEV. = -10.1 DEGREES REMARK 500 REMARK 500 THIS ENTRY HAS 78 ANGLE DEVIATIONS. REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: PLANAR GROUPS REMARK 500 REMARK 500 PLANAR GROUPS IN THE FOLLOWING RESIDUES HAVE A TOTAL REMARK 500 RMS DISTANCE OF ALL ATOMS FROM THE BEST-FIT PLANE REMARK 500 BY MORE THAN AN EXPECTED VALUE OF 6*RMSD, WITH AN REMARK 500 RMSD 0.02 ANGSTROMS, OR AT LEAST ONE ATOM HAS REMARK 500 AN RMSD GREATER THAN THIS VALUE REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 M RES CSSEQI RMS TYPE REMARK 500 A A 2 0.07 SIDE_CHAIN REMARK 500 REMARK 500 REMARK: NULL REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 1NTQ RELATED DB: PDB REMARK 900 DNA:RNA HYBRID WITH SAME SEQUENCE REMARK 900 RELATED ID: 1NTT RELATED DB: PDB REMARK 900 DNA:RNA HYBRID WITH PROPYNYLATED BASES 2-7 IN DNA STRAND DBREF 1NTS A 2 10 PDB 1NTS 1NTS 2 10 DBREF 1NTS B 1 7 PDB 1NTS 1NTS 1 7 SEQRES 1 A 9 A A A G G A G G A SEQRES 1 B 7 5PC 5PC PDU 5PC 5PC PDU PDU MODRES 1NTS 5PC B 1 DC MODRES 1NTS 5PC B 2 DC MODRES 1NTS PDU B 3 DU MODRES 1NTS 5PC B 4 DC MODRES 1NTS 5PC B 5 DC MODRES 1NTS PDU B 6 DU MODRES 1NTS PDU B 7 DU HET 5PC B 1 33 HET 5PC B 2 35 HET PDU B 3 34 HET 5PC B 4 35 HET 5PC B 5 35 HET PDU B 6 34 HET PDU B 7 35 HETNAM 5PC 5(1-PROPYNYL)-2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE HETNAM PDU 5(1-PROPYNYL)-2'-DEOXYURIDINE-5-MONOPHOSPHATE FORMUL 2 5PC 4(C12 H16 N3 O7 P) FORMUL 2 PDU 3(C12 H19 N2 O8 P) LINK O3' 5PC B 1 P 5PC B 2 1555 1555 1.62 LINK O3' 5PC B 2 P PDU B 3 1555 1555 1.62 LINK O3' PDU B 3 P 5PC B 4 1555 1555 1.62 LINK O3' 5PC B 4 P 5PC B 5 1555 1555 1.63 LINK O3' 5PC B 5 P PDU B 6 1555 1555 1.63 LINK O3' PDU B 6 P PDU B 7 1555 1555 1.63 CRYST1 1.000 1.000 1.000 90.00 90.00 90.00 P 1 1 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 1.000000 0.000000 0.000000 0.00000 SCALE2 0.000000 1.000000 0.000000 0.00000 SCALE3 0.000000 0.000000 1.000000 0.00000 USER MOD ----------------------------------------------------------------- USER MOD scores for adjustable sidechains, with "set" totals for H,N and Q USER MOD "o" means original, "f" means flipped, "180deg" is methyl default USER MOD "!" flags a clash with an overlap of 0.40A or greater USER MOD flip categories: "K"=keep, "C"=clashes, "X"=uncertain, "F"=flip USER MOD NoAdj-H: B 3 PDUH5B2 : B 3 PDU C5B : B 3 PDU C5M :(H bumps) USER MOD NoAdj-H: B 3 PDUH5B1 : B 3 PDU C5B : B 3 PDU C5M :(H bumps) USER MOD NoAdj-H: B 3 PDUH5A2 : B 3 PDU C5A : B 3 PDU C5B :(H bumps) USER MOD NoAdj-H: B 3 PDUH5A1 : B 3 PDU C5A : B 3 PDU C5B :(H bumps) USER MOD NoAdj-H: B 6 PDUH5B2 : B 6 PDU C5B : B 6 PDU C5M :(H bumps) USER MOD NoAdj-H: B 6 PDUH5B1 : B 6 PDU C5B : B 6 PDU C5M :(H bumps) USER MOD NoAdj-H: B 6 PDUH5A2 : B 6 PDU C5A : B 6 PDU C5B :(H bumps) USER MOD NoAdj-H: B 6 PDUH5A1 : B 6 PDU C5A : B 6 PDU C5B :(H bumps) USER MOD NoAdj-H: B 7 PDUH5B2 : B 7 PDU C5B : B 7 PDU C5M :(H bumps) USER MOD NoAdj-H: B 7 PDUH5B1 : B 7 PDU C5B : B 7 PDU C5M :(H bumps) USER MOD NoAdj-H: B 7 PDUH5A2 : B 7 PDU C5A : B 7 PDU C5B :(H bumps) USER MOD NoAdj-H: B 7 PDUH5A1 : B 7 PDU C5A : B 7 PDU C5B :(H bumps) USER MOD Single : A 2 A O2' : rot -20:sc= 0.118 USER MOD Single : A 2 A O5' : rot -92:sc= 1.22 USER MOD Single : A 3 A O2' : rot -122:sc= 0.996 USER MOD Single : A 4 A O2' : rot -16:sc= 0.106 USER MOD Single : A 5 G O2' : rot -15:sc= 0.141 USER MOD Single : A 6 G O2' : rot -20:sc= 0.121 USER MOD Single : A 7 A O2' : rot -16:sc= 0.118 USER MOD Single : A 8 G O2' : rot -17:sc= 0.121 USER MOD Single : A 9 G O2' : rot -24:sc= 0.165 USER MOD Single : A 10 A O2' : rot -17:sc= 0.185 USER MOD Single : A 10 A O3' : rot 180:sc= 0.186 USER MOD Single : B 7 PDU O3' : rot 180:sc= 0 USER MOD ----------------------------------------------------------------- ATOM 1 O5' A A 2 7.575 -4.433 12.055 1.00 0.00 O ATOM 2 C5' A A 2 7.904 -5.000 13.324 1.00 0.00 C ATOM 3 C4' A A 2 6.998 -6.190 13.711 1.00 0.00 C ATOM 4 O4' A A 2 5.770 -5.764 14.321 1.00 0.00 O ATOM 5 C3' A A 2 6.544 -7.083 12.554 1.00 0.00 C ATOM 6 O3' A A 2 7.605 -7.940 12.097 1.00 0.00 O ATOM 7 C2' A A 2 5.356 -7.831 13.146 1.00 0.00 C ATOM 8 O2' A A 2 5.815 -8.970 13.871 1.00 0.00 O ATOM 9 C1' A A 2 4.750 -6.776 14.103 1.00 0.00 C ATOM 10 N9 A A 2 3.494 -6.147 13.571 1.00 0.00 N ATOM 11 C8 A A 2 3.170 -4.802 13.407 1.00 0.00 C ATOM 12 N7 A A 2 1.883 -4.378 13.154 1.00 0.00 N ATOM 13 C5 A A 2 1.281 -5.629 13.133 1.00 0.00 C ATOM 14 C6 A A 2 -0.107 -5.992 12.928 1.00 0.00 C ATOM 15 N6 A A 2 -1.051 -5.077 12.736 1.00 0.00 N ATOM 16 N1 A A 2 -0.470 -7.260 12.930 1.00 0.00 N ATOM 17 C2 A A 2 0.429 -8.201 13.126 1.00 0.00 C ATOM 18 N3 A A 2 1.714 -8.082 13.345 1.00 0.00 N ATOM 19 C4 A A 2 2.234 -6.712 13.362 1.00 0.00 C ATOM 0 H5' A A 2 7.827 -4.229 14.090 1.00 0.00 H new ATOM 0 H5'' A A 2 8.942 -5.332 13.309 1.00 0.00 H new ATOM 0 H4' A A 2 7.651 -6.748 14.382 1.00 0.00 H new ATOM 0 H3' A A 2 6.267 -6.535 11.654 1.00 0.00 H new ATOM 0 H2' A A 2 4.646 -8.205 12.408 1.00 0.00 H new ATOM 0 HO2' A A 2 6.722 -9.200 13.579 1.00 0.00 H new ATOM 0 HO5' A A 2 8.110 -4.864 11.356 1.00 0.00 H new ATOM 0 H1' A A 2 4.459 -7.266 15.032 1.00 0.00 H new ATOM 0 H8 A A 2 3.956 -4.065 13.481 1.00 0.00 H new ATOM 0 H61 A A 2 -2.019 -5.365 12.595 1.00 0.00 H new ATOM 0 H62 A A 2 -0.807 -4.087 12.730 1.00 0.00 H new ATOM 0 H2 A A 2 0.054 -9.213 13.103 1.00 0.00 H new ATOM 32 P A A 3 8.242 -7.732 10.625 1.00 0.00 P ATOM 33 OP1 A A 3 9.614 -8.403 10.561 1.00 0.00 O ATOM 34 OP2 A A 3 8.382 -6.227 10.359 1.00 0.00 O ATOM 35 O5' A A 3 7.237 -8.396 9.548 1.00 0.00 O ATOM 36 C5' A A 3 7.087 -9.825 9.431 1.00 0.00 C ATOM 37 C4' A A 3 5.656 -10.211 9.022 1.00 0.00 C ATOM 38 O4' A A 3 4.723 -9.712 10.004 1.00 0.00 O ATOM 39 C3' A A 3 5.172 -9.676 7.667 1.00 0.00 C ATOM 40 O3' A A 3 5.617 -10.501 6.571 1.00 0.00 O ATOM 41 C2' A A 3 3.650 -9.679 7.863 1.00 0.00 C ATOM 42 O2' A A 3 3.086 -10.961 7.592 1.00 0.00 O ATOM 43 C1' A A 3 3.485 -9.349 9.359 1.00 0.00 C ATOM 44 N9 A A 3 3.176 -7.899 9.569 1.00 0.00 N ATOM 45 C8 A A 3 4.018 -6.803 9.720 1.00 0.00 C ATOM 46 N7 A A 3 3.543 -5.510 9.746 1.00 0.00 N ATOM 47 C5 A A 3 2.198 -5.811 9.582 1.00 0.00 C ATOM 48 C6 A A 3 1.049 -4.934 9.505 1.00 0.00 C ATOM 49 N6 A A 3 1.164 -3.615 9.603 1.00 0.00 N ATOM 50 N1 A A 3 -0.158 -5.438 9.347 1.00 0.00 N ATOM 51 C2 A A 3 -0.327 -6.740 9.260 1.00 0.00 C ATOM 52 N3 A A 3 0.569 -7.690 9.305 1.00 0.00 N ATOM 53 C4 A A 3 1.953 -7.246 9.482 1.00 0.00 C ATOM 0 H5' A A 3 7.334 -10.297 10.382 1.00 0.00 H new ATOM 0 H5'' A A 3 7.793 -10.207 8.693 1.00 0.00 H new ATOM 0 H4' A A 3 5.692 -11.298 8.949 1.00 0.00 H new ATOM 0 H3' A A 3 5.564 -8.694 7.400 1.00 0.00 H new ATOM 0 H2' A A 3 3.149 -8.980 7.194 1.00 0.00 H new ATOM 0 HO2' A A 3 2.416 -10.880 6.881 1.00 0.00 H new ATOM 0 H1' A A 3 2.647 -9.904 9.782 1.00 0.00 H new ATOM 0 H8 A A 3 5.080 -6.971 9.820 1.00 0.00 H new ATOM 0 H61 A A 3 0.334 -3.025 9.545 1.00 0.00 H new ATOM 0 H62 A A 3 2.082 -3.192 9.737 1.00 0.00 H new ATOM 0 H2 A A 3 -1.348 -7.069 9.134 1.00 0.00 H new ATOM 65 P A A 4 5.492 -10.037 5.021 1.00 0.00 P ATOM 66 OP1 A A 4 6.310 -10.988 4.145 1.00 0.00 O ATOM 67 OP2 A A 4 6.029 -8.613 4.868 1.00 0.00 O ATOM 68 O5' A A 4 3.938 -10.075 4.564 1.00 0.00 O ATOM 69 C5' A A 4 3.230 -11.309 4.344 1.00 0.00 C ATOM 70 C4' A A 4 1.706 -11.092 4.356 1.00 0.00 C ATOM 71 O4' A A 4 1.297 -10.337 5.519 1.00 0.00 O ATOM 72 C3' A A 4 1.140 -10.328 3.149 1.00 0.00 C ATOM 73 O3' A A 4 0.948 -11.177 2.000 1.00 0.00 O ATOM 74 C2' A A 4 -0.185 -9.817 3.722 1.00 0.00 C ATOM 75 O2' A A 4 -1.171 -10.847 3.677 1.00 0.00 O ATOM 76 C1' A A 4 0.169 -9.494 5.182 1.00 0.00 C ATOM 77 N9 A A 4 0.491 -8.042 5.378 1.00 0.00 N ATOM 78 C8 A A 4 1.700 -7.356 5.301 1.00 0.00 C ATOM 79 N7 A A 4 1.785 -5.995 5.498 1.00 0.00 N ATOM 80 C5 A A 4 0.434 -5.758 5.714 1.00 0.00 C ATOM 81 C6 A A 4 -0.264 -4.518 5.986 1.00 0.00 C ATOM 82 N6 A A 4 0.379 -3.360 6.071 1.00 0.00 N ATOM 83 N1 A A 4 -1.571 -4.514 6.163 1.00 0.00 N ATOM 84 C2 A A 4 -2.249 -5.638 6.085 1.00 0.00 C ATOM 85 N3 A A 4 -1.812 -6.849 5.851 1.00 0.00 N ATOM 86 C4 A A 4 -0.366 -6.976 5.645 1.00 0.00 C ATOM 0 H5' A A 4 3.503 -12.029 5.115 1.00 0.00 H new ATOM 0 H5'' A A 4 3.531 -11.737 3.388 1.00 0.00 H new ATOM 0 H4' A A 4 1.314 -12.109 4.343 1.00 0.00 H new ATOM 0 H3' A A 4 1.796 -9.544 2.771 1.00 0.00 H new ATOM 0 H2' A A 4 -0.592 -8.967 3.175 1.00 0.00 H new ATOM 0 HO2' A A 4 -0.876 -11.556 3.069 1.00 0.00 H new ATOM 0 H1' A A 4 -0.681 -9.689 5.836 1.00 0.00 H new ATOM 0 H8 A A 4 2.601 -7.909 5.080 1.00 0.00 H new ATOM 0 H61 A A 4 -0.138 -2.502 6.264 1.00 0.00 H new ATOM 0 H62 A A 4 1.391 -3.328 5.944 1.00 0.00 H new ATOM 0 H2 A A 4 -3.315 -5.549 6.235 1.00 0.00 H new ATOM 98 P G A 5 0.753 -10.577 0.504 1.00 0.00 P ATOM 99 OP1 G A 5 0.746 -11.732 -0.498 1.00 0.00 O ATOM 100 OP2 G A 5 1.905 -9.626 0.182 1.00 0.00 O ATOM 101 O5' G A 5 -0.652 -9.771 0.421 1.00 0.00 O ATOM 102 C5' G A 5 -1.922 -10.449 0.380 1.00 0.00 C ATOM 103 C4' G A 5 -3.093 -9.502 0.698 1.00 0.00 C ATOM 104 O4' G A 5 -2.879 -8.798 1.939 1.00 0.00 O ATOM 105 C3' G A 5 -3.363 -8.415 -0.351 1.00 0.00 C ATOM 106 O3' G A 5 -4.116 -8.926 -1.470 1.00 0.00 O ATOM 107 C2' G A 5 -4.150 -7.393 0.475 1.00 0.00 C ATOM 108 O2' G A 5 -5.522 -7.774 0.551 1.00 0.00 O ATOM 109 C1' G A 5 -3.497 -7.492 1.869 1.00 0.00 C ATOM 110 N9 G A 5 -2.489 -6.402 2.090 1.00 0.00 N ATOM 111 C8 G A 5 -1.104 -6.401 1.975 1.00 0.00 C ATOM 112 N7 G A 5 -0.359 -5.264 2.194 1.00 0.00 N ATOM 113 C5 G A 5 -1.413 -4.420 2.485 1.00 0.00 C ATOM 114 C6 G A 5 -1.328 -2.918 2.866 1.00 0.00 C ATOM 115 O6 G A 5 -0.274 -2.292 2.952 1.00 0.00 O ATOM 116 N1 G A 5 -2.524 -2.315 3.107 1.00 0.00 N ATOM 117 C2 G A 5 -3.809 -3.012 2.996 1.00 0.00 C ATOM 118 N2 G A 5 -4.989 -2.297 3.183 1.00 0.00 N ATOM 119 N3 G A 5 -3.865 -4.270 2.709 1.00 0.00 N ATOM 120 C4 G A 5 -2.693 -5.069 2.429 1.00 0.00 C ATOM 0 H5' G A 5 -1.917 -11.272 1.095 1.00 0.00 H new ATOM 0 H5'' G A 5 -2.068 -10.886 -0.608 1.00 0.00 H new ATOM 0 H4' G A 5 -3.947 -10.179 0.733 1.00 0.00 H new ATOM 0 H3' G A 5 -2.468 -8.003 -0.816 1.00 0.00 H new ATOM 0 H2' G A 5 -4.125 -6.388 0.054 1.00 0.00 H new ATOM 0 HO2' G A 5 -5.710 -8.456 -0.127 1.00 0.00 H new ATOM 0 H1' G A 5 -4.244 -7.368 2.653 1.00 0.00 H new ATOM 0 H8 G A 5 -0.598 -7.317 1.707 1.00 0.00 H new ATOM 0 H1 G A 5 -2.526 -1.332 3.378 1.00 0.00 H new ATOM 0 H21 G A 5 -5.889 -2.770 3.108 1.00 0.00 H new ATOM 0 H22 G A 5 -4.953 -1.300 3.395 1.00 0.00 H new ATOM 132 P G A 6 -4.147 -8.188 -2.914 1.00 0.00 P ATOM 133 OP1 G A 6 -4.819 -9.113 -3.931 1.00 0.00 O ATOM 134 OP2 G A 6 -2.719 -7.882 -3.367 1.00 0.00 O ATOM 135 O5' G A 6 -4.983 -6.807 -2.799 1.00 0.00 O ATOM 136 C5' G A 6 -6.415 -6.787 -2.659 1.00 0.00 C ATOM 137 C4' G A 6 -6.923 -5.411 -2.196 1.00 0.00 C ATOM 138 O4' G A 6 -6.254 -4.988 -0.985 1.00 0.00 O ATOM 139 C3' G A 6 -6.731 -4.265 -3.201 1.00 0.00 C ATOM 140 O3' G A 6 -7.767 -4.231 -4.203 1.00 0.00 O ATOM 141 C2' G A 6 -6.790 -3.052 -2.272 1.00 0.00 C ATOM 142 O2' G A 6 -8.149 -2.733 -1.972 1.00 0.00 O ATOM 143 C1' G A 6 -6.072 -3.552 -1.011 1.00 0.00 C ATOM 144 N9 G A 6 -4.617 -3.186 -0.986 1.00 0.00 N ATOM 145 C8 G A 6 -3.481 -3.924 -1.300 1.00 0.00 C ATOM 146 N7 G A 6 -2.214 -3.430 -1.089 1.00 0.00 N ATOM 147 C5 G A 6 -2.590 -2.197 -0.594 1.00 0.00 C ATOM 148 C6 G A 6 -1.652 -1.051 -0.133 1.00 0.00 C ATOM 149 O6 G A 6 -0.426 -1.132 -0.133 1.00 0.00 O ATOM 150 N1 G A 6 -2.284 0.081 0.284 1.00 0.00 N ATOM 151 C2 G A 6 -3.742 0.231 0.282 1.00 0.00 C ATOM 152 N2 G A 6 -4.303 1.456 0.636 1.00 0.00 N ATOM 153 N3 G A 6 -4.513 -0.744 -0.069 1.00 0.00 N ATOM 154 C4 G A 6 -4.014 -2.017 -0.537 1.00 0.00 C ATOM 0 H5' G A 6 -6.721 -7.548 -1.941 1.00 0.00 H new ATOM 0 H5'' G A 6 -6.877 -7.044 -3.612 1.00 0.00 H new ATOM 0 H4' G A 6 -7.991 -5.578 -2.058 1.00 0.00 H new ATOM 0 H3' G A 6 -5.816 -4.339 -3.789 1.00 0.00 H new ATOM 0 H2' G A 6 -6.343 -2.153 -2.697 1.00 0.00 H new ATOM 0 HO2' G A 6 -8.735 -3.125 -2.653 1.00 0.00 H new ATOM 0 H1' G A 6 -6.495 -3.077 -0.126 1.00 0.00 H new ATOM 0 H8 G A 6 -3.596 -4.912 -1.721 1.00 0.00 H new ATOM 0 H1 G A 6 -1.716 0.861 0.613 1.00 0.00 H new ATOM 0 H21 G A 6 -5.316 1.571 0.638 1.00 0.00 H new ATOM 0 H22 G A 6 -3.700 2.238 0.893 1.00 0.00 H new ATOM 166 P A A 7 -7.575 -3.453 -5.615 1.00 0.00 P ATOM 167 OP1 A A 7 -8.807 -3.698 -6.489 1.00 0.00 O ATOM 168 OP2 A A 7 -6.331 -3.985 -6.326 1.00 0.00 O ATOM 169 O5' A A 7 -7.403 -1.863 -5.344 1.00 0.00 O ATOM 170 C5' A A 7 -8.516 -1.021 -4.989 1.00 0.00 C ATOM 171 C4' A A 7 -8.058 0.353 -4.468 1.00 0.00 C ATOM 172 O4' A A 7 -7.162 0.214 -3.344 1.00 0.00 O ATOM 173 C3' A A 7 -7.315 1.232 -5.485 1.00 0.00 C ATOM 174 O3' A A 7 -8.220 1.924 -6.370 1.00 0.00 O ATOM 175 C2' A A 7 -6.560 2.186 -4.554 1.00 0.00 C ATOM 176 O2' A A 7 -7.423 3.238 -4.124 1.00 0.00 O ATOM 177 C1' A A 7 -6.188 1.284 -3.362 1.00 0.00 C ATOM 178 N9 A A 7 -4.793 0.746 -3.481 1.00 0.00 N ATOM 179 C8 A A 7 -4.327 -0.502 -3.885 1.00 0.00 C ATOM 180 N7 A A 7 -2.985 -0.812 -3.911 1.00 0.00 N ATOM 181 C5 A A 7 -2.509 0.408 -3.450 1.00 0.00 C ATOM 182 C6 A A 7 -1.154 0.829 -3.164 1.00 0.00 C ATOM 183 N6 A A 7 -0.119 0.017 -3.344 1.00 0.00 N ATOM 184 N1 A A 7 -0.921 2.040 -2.696 1.00 0.00 N ATOM 185 C2 A A 7 -1.918 2.874 -2.494 1.00 0.00 C ATOM 186 N3 A A 7 -3.199 2.684 -2.677 1.00 0.00 N ATOM 187 C4 A A 7 -3.580 1.363 -3.186 1.00 0.00 C ATOM 0 H5' A A 7 -9.116 -1.516 -4.226 1.00 0.00 H new ATOM 0 H5'' A A 7 -9.158 -0.883 -5.859 1.00 0.00 H new ATOM 0 H4' A A 7 -8.999 0.839 -4.209 1.00 0.00 H new ATOM 0 H3' A A 7 -6.671 0.680 -6.169 1.00 0.00 H new ATOM 0 H2' A A 7 -5.699 2.660 -5.024 1.00 0.00 H new ATOM 0 HO2' A A 7 -8.215 3.267 -4.700 1.00 0.00 H new ATOM 0 H1' A A 7 -6.205 1.851 -2.431 1.00 0.00 H new ATOM 0 H8 A A 7 -5.042 -1.253 -4.188 1.00 0.00 H new ATOM 0 H61 A A 7 0.825 0.340 -3.134 1.00 0.00 H new ATOM 0 H62 A A 7 -0.268 -0.930 -3.692 1.00 0.00 H new ATOM 0 H2 A A 7 -1.640 3.851 -2.126 1.00 0.00 H new ATOM 199 P G A 8 -7.744 2.530 -7.799 1.00 0.00 P ATOM 200 OP1 G A 8 -8.977 2.995 -8.577 1.00 0.00 O ATOM 201 OP2 G A 8 -7.013 1.452 -8.598 1.00 0.00 O ATOM 202 O5' G A 8 -6.750 3.785 -7.552 1.00 0.00 O ATOM 203 C5' G A 8 -7.231 5.065 -7.102 1.00 0.00 C ATOM 204 C4' G A 8 -6.086 5.968 -6.613 1.00 0.00 C ATOM 205 O4' G A 8 -5.303 5.308 -5.595 1.00 0.00 O ATOM 206 C3' G A 8 -5.082 6.406 -7.690 1.00 0.00 C ATOM 207 O3' G A 8 -5.563 7.526 -8.462 1.00 0.00 O ATOM 208 C2' G A 8 -3.868 6.769 -6.831 1.00 0.00 C ATOM 209 O2' G A 8 -4.022 8.082 -6.296 1.00 0.00 O ATOM 210 C1' G A 8 -3.921 5.722 -5.701 1.00 0.00 C ATOM 211 N9 G A 8 -3.026 4.551 -5.980 1.00 0.00 N ATOM 212 C8 G A 8 -3.306 3.281 -6.470 1.00 0.00 C ATOM 213 N7 G A 8 -2.326 2.324 -6.607 1.00 0.00 N ATOM 214 C5 G A 8 -1.271 3.095 -6.163 1.00 0.00 C ATOM 215 C6 G A 8 0.215 2.667 -6.056 1.00 0.00 C ATOM 216 O6 G A 8 0.622 1.541 -6.334 1.00 0.00 O ATOM 217 N1 G A 8 1.069 3.641 -5.639 1.00 0.00 N ATOM 218 C2 G A 8 0.636 5.007 -5.328 1.00 0.00 C ATOM 219 N2 G A 8 1.592 5.970 -5.010 1.00 0.00 N ATOM 220 N3 G A 8 -0.611 5.339 -5.375 1.00 0.00 N ATOM 221 C4 G A 8 -1.654 4.430 -5.799 1.00 0.00 C ATOM 0 H5' G A 8 -7.949 4.920 -6.295 1.00 0.00 H new ATOM 0 H5'' G A 8 -7.762 5.560 -7.915 1.00 0.00 H new ATOM 0 H4' G A 8 -6.611 6.851 -6.248 1.00 0.00 H new ATOM 0 H3' G A 8 -4.880 5.648 -8.447 1.00 0.00 H new ATOM 0 H2' G A 8 -2.927 6.765 -7.381 1.00 0.00 H new ATOM 0 HO2' G A 8 -4.717 8.559 -6.795 1.00 0.00 H new ATOM 0 H1' G A 8 -3.562 6.151 -4.765 1.00 0.00 H new ATOM 0 H8 G A 8 -4.320 3.038 -6.751 1.00 0.00 H new ATOM 0 H1 G A 8 2.057 3.410 -5.538 1.00 0.00 H new ATOM 0 H21 G A 8 1.303 6.923 -4.792 1.00 0.00 H new ATOM 0 H22 G A 8 2.581 5.721 -4.995 1.00 0.00 H new ATOM 233 P G A 9 -5.026 7.848 -9.959 1.00 0.00 P ATOM 234 OP1 G A 9 -5.875 8.970 -10.563 1.00 0.00 O ATOM 235 OP2 G A 9 -5.143 6.597 -10.829 1.00 0.00 O ATOM 236 O5' G A 9 -3.475 8.314 -9.897 1.00 0.00 O ATOM 237 C5' G A 9 -3.081 9.609 -9.409 1.00 0.00 C ATOM 238 C4' G A 9 -1.576 9.663 -9.094 1.00 0.00 C ATOM 239 O4' G A 9 -1.211 8.611 -8.174 1.00 0.00 O ATOM 240 C3' G A 9 -0.636 9.510 -10.302 1.00 0.00 C ATOM 241 O3' G A 9 -0.424 10.755 -11.000 1.00 0.00 O ATOM 242 C2' G A 9 0.643 9.018 -9.621 1.00 0.00 C ATOM 243 O2' G A 9 1.359 10.126 -9.077 1.00 0.00 O ATOM 244 C1' G A 9 0.114 8.127 -8.487 1.00 0.00 C ATOM 245 N9 G A 9 0.091 6.678 -8.868 1.00 0.00 N ATOM 246 C8 G A 9 -0.956 5.843 -9.241 1.00 0.00 C ATOM 247 N7 G A 9 -0.768 4.497 -9.458 1.00 0.00 N ATOM 248 C5 G A 9 0.590 4.472 -9.205 1.00 0.00 C ATOM 249 C6 G A 9 1.527 3.241 -9.277 1.00 0.00 C ATOM 250 O6 G A 9 1.141 2.105 -9.540 1.00 0.00 O ATOM 251 N1 G A 9 2.842 3.497 -9.038 1.00 0.00 N ATOM 252 C2 G A 9 3.356 4.844 -8.770 1.00 0.00 C ATOM 253 N2 G A 9 4.733 5.042 -8.681 1.00 0.00 N ATOM 254 N3 G A 9 2.559 5.853 -8.659 1.00 0.00 N ATOM 255 C4 G A 9 1.132 5.758 -8.875 1.00 0.00 C ATOM 0 H5' G A 9 -3.650 9.848 -8.511 1.00 0.00 H new ATOM 0 H5'' G A 9 -3.325 10.368 -10.152 1.00 0.00 H new ATOM 0 H4' G A 9 -1.443 10.664 -8.684 1.00 0.00 H new ATOM 0 H3' G A 9 -1.021 8.846 -11.076 1.00 0.00 H new ATOM 0 H2' G A 9 1.323 8.499 -10.297 1.00 0.00 H new ATOM 0 HO2' G A 9 1.113 10.943 -9.559 1.00 0.00 H new ATOM 0 H1' G A 9 0.771 8.185 -7.620 1.00 0.00 H new ATOM 0 H8 G A 9 -1.944 6.262 -9.364 1.00 0.00 H new ATOM 0 H1 G A 9 3.499 2.717 -9.046 1.00 0.00 H new ATOM 0 H21 G A 9 5.103 5.974 -8.495 1.00 0.00 H new ATOM 0 H22 G A 9 5.370 4.255 -8.802 1.00 0.00 H new ATOM 267 P A A 10 0.098 10.809 -12.537 1.00 0.00 P ATOM 268 OP1 A A 10 0.234 12.270 -12.971 1.00 0.00 O ATOM 269 OP2 A A 10 -0.908 10.100 -13.443 1.00 0.00 O ATOM 270 O5' A A 10 1.535 10.070 -12.661 1.00 0.00 O ATOM 271 C5' A A 10 2.763 10.668 -12.201 1.00 0.00 C ATOM 272 C4' A A 10 3.922 9.654 -12.210 1.00 0.00 C ATOM 273 O4' A A 10 3.608 8.513 -11.389 1.00 0.00 O ATOM 274 C3' A A 10 4.276 9.088 -13.592 1.00 0.00 C ATOM 275 O3' A A 10 5.170 9.933 -14.307 1.00 0.00 O ATOM 276 C2' A A 10 4.922 7.744 -13.247 1.00 0.00 C ATOM 277 O2' A A 10 6.312 7.910 -12.957 1.00 0.00 O ATOM 278 C1' A A 10 4.165 7.314 -11.970 1.00 0.00 C ATOM 279 N9 A A 10 3.091 6.312 -12.265 1.00 0.00 N ATOM 280 C8 A A 10 1.717 6.470 -12.435 1.00 0.00 C ATOM 281 N7 A A 10 0.886 5.404 -12.703 1.00 0.00 N ATOM 282 C5 A A 10 1.855 4.408 -12.691 1.00 0.00 C ATOM 283 C6 A A 10 1.720 2.973 -12.842 1.00 0.00 C ATOM 284 N6 A A 10 0.541 2.400 -13.050 1.00 0.00 N ATOM 285 N1 A A 10 2.778 2.190 -12.747 1.00 0.00 N ATOM 286 C2 A A 10 3.962 2.713 -12.510 1.00 0.00 C ATOM 287 N3 A A 10 4.292 3.968 -12.344 1.00 0.00 N ATOM 288 C4 A A 10 3.190 4.932 -12.424 1.00 0.00 C ATOM 0 H5' A A 10 2.625 11.055 -11.192 1.00 0.00 H new ATOM 0 H5'' A A 10 3.016 11.517 -12.836 1.00 0.00 H new ATOM 0 H4' A A 10 4.770 10.230 -11.838 1.00 0.00 H new ATOM 0 H3' A A 10 3.411 8.999 -14.250 1.00 0.00 H new ATOM 0 H2' A A 10 4.861 7.020 -14.060 1.00 0.00 H new ATOM 0 HO2' A A 10 6.617 8.775 -13.303 1.00 0.00 H new ATOM 0 HO3' A A 10 5.370 9.534 -15.180 1.00 0.00 H new ATOM 0 H1' A A 10 4.849 6.823 -11.277 1.00 0.00 H new ATOM 0 H8 A A 10 1.290 7.459 -12.354 1.00 0.00 H new ATOM 0 H61 A A 10 0.477 1.387 -13.152 1.00 0.00 H new ATOM 0 H62 A A 10 -0.301 2.973 -13.107 1.00 0.00 H new ATOM 0 H2 A A 10 4.776 2.007 -12.443 1.00 0.00 H new TER 301 A A 10 HETATM 302 C5' 5PC B 1 10.086 -2.787 -8.580 1.00 0.00 C HETATM 303 O5' 5PC B 1 10.409 -3.460 -9.791 1.00 0.00 O HETATM 304 C4' 5PC B 1 10.094 -1.267 -8.811 1.00 0.00 C HETATM 305 O4' 5PC B 1 9.151 -0.906 -9.848 1.00 0.00 O HETATM 306 C3' 5PC B 1 9.693 -0.451 -7.575 1.00 0.00 C HETATM 307 O3' 5PC B 1 10.810 -0.198 -6.709 1.00 0.00 O HETATM 308 C2' 5PC B 1 9.191 0.825 -8.236 1.00 0.00 C HETATM 309 C1' 5PC B 1 8.467 0.320 -9.487 1.00 0.00 C HETATM 310 N1 5PC B 1 6.991 0.116 -9.327 1.00 0.00 N HETATM 311 C2 5PC B 1 6.108 1.177 -9.476 1.00 0.00 C HETATM 312 O2 5PC B 1 6.512 2.322 -9.688 1.00 0.00 O HETATM 313 N3 5PC B 1 4.673 0.894 -9.373 1.00 0.00 N HETATM 314 C4 5PC B 1 4.210 -0.295 -9.130 1.00 0.00 C HETATM 315 N4 5PC B 1 2.793 -0.396 -9.062 1.00 0.00 N HETATM 316 C5 5PC B 1 5.045 -1.382 -8.947 1.00 0.00 C HETATM 317 C6 5PC B 1 6.403 -1.229 -9.040 1.00 0.00 C HETATM 318 C7 5PC B 1 4.606 -2.727 -8.636 1.00 0.00 C HETATM 319 C8 5PC B 1 4.239 -3.844 -8.370 1.00 0.00 C HETATM 320 C9 5PC B 1 3.815 -5.139 -8.056 1.00 0.00 C HETATM 0 H5'' 5PC B 1 9.105 -3.105 -8.227 1.00 0.00 H new HETATM 0 H2'' 5PC B 1 8.520 1.379 -7.580 1.00 0.00 H new HETATM 0 H93 5PC B 1 4.664 -5.724 -7.702 1.00 0.00 H new HETATM 0 H92 5PC B 1 3.055 -5.094 -7.276 1.00 0.00 H new HETATM 0 H91 5PC B 1 3.396 -5.610 -8.945 1.00 0.00 H new HETATM 0 H6 5PC B 1 7.057 -2.090 -8.904 1.00 0.00 H new HETATM 0 H5' 5PC B 1 10.805 -3.050 -7.804 1.00 0.00 H new HETATM 0 H42 5PC B 1 2.354 -1.298 -8.875 1.00 0.00 H new HETATM 0 H41 5PC B 1 2.215 0.433 -9.201 1.00 0.00 H new HETATM 0 H4' 5PC B 1 11.124 -1.034 -9.080 1.00 0.00 H new HETATM 0 H3' 5PC B 1 8.969 -0.943 -6.926 1.00 0.00 H new HETATM 0 H2' 5PC B 1 10.012 1.495 -8.491 1.00 0.00 H new HETATM 0 H1' 5PC B 1 8.514 1.077 -10.270 1.00 0.00 H new HETATM 335 P 5PC B 2 10.628 0.039 -5.117 1.00 0.00 P HETATM 336 OP1 5PC B 2 12.007 0.130 -4.461 1.00 0.00 O HETATM 337 OP2 5PC B 2 9.854 -1.136 -4.518 1.00 0.00 O HETATM 338 C5' 5PC B 2 10.355 2.708 -5.158 1.00 0.00 C HETATM 339 O5' 5PC B 2 9.807 1.411 -4.858 1.00 0.00 O HETATM 340 C4' 5PC B 2 9.260 3.790 -5.226 1.00 0.00 C HETATM 341 O4' 5PC B 2 8.286 3.470 -6.242 1.00 0.00 O HETATM 342 C3' 5PC B 2 8.474 4.009 -3.926 1.00 0.00 C HETATM 343 O3' 5PC B 2 9.158 4.928 -3.055 1.00 0.00 O HETATM 344 C2' 5PC B 2 7.178 4.595 -4.477 1.00 0.00 C HETATM 345 C1' 5PC B 2 6.965 3.872 -5.815 1.00 0.00 C HETATM 346 N1 5PC B 2 6.007 2.720 -5.737 1.00 0.00 N HETATM 347 C2 5PC B 2 4.641 2.948 -5.667 1.00 0.00 C HETATM 348 O2 5PC B 2 4.183 4.092 -5.645 1.00 0.00 O HETATM 349 N3 5PC B 2 3.753 1.784 -5.598 1.00 0.00 N HETATM 350 C4 5PC B 2 4.200 0.567 -5.539 1.00 0.00 C HETATM 351 N4 5PC B 2 3.200 -0.439 -5.440 1.00 0.00 N HETATM 352 C5 5PC B 2 5.552 0.282 -5.578 1.00 0.00 C HETATM 353 C6 5PC B 2 6.464 1.296 -5.700 1.00 0.00 C HETATM 354 C7 5PC B 2 6.128 -1.044 -5.505 1.00 0.00 C HETATM 355 C8 5PC B 2 6.613 -2.145 -5.448 1.00 0.00 C HETATM 356 C9 5PC B 2 7.182 -3.421 -5.386 1.00 0.00 C HETATM 0 H5'' 5PC B 2 11.087 2.979 -4.397 1.00 0.00 H new HETATM 0 H2'' 5PC B 2 6.344 4.423 -3.796 1.00 0.00 H new HETATM 0 H93 5PC B 2 7.291 -3.820 -6.394 1.00 0.00 H new HETATM 0 H92 5PC B 2 8.162 -3.360 -4.912 1.00 0.00 H new HETATM 0 H91 5PC B 2 6.537 -4.079 -4.803 1.00 0.00 H new HETATM 0 H6 5PC B 2 7.527 1.065 -5.770 1.00 0.00 H new HETATM 0 H5' 5PC B 2 10.885 2.667 -6.109 1.00 0.00 H new HETATM 0 H42 5PC B 2 3.468 -1.422 -5.389 1.00 0.00 H new HETATM 0 H41 5PC B 2 2.214 -0.178 -5.420 1.00 0.00 H new HETATM 0 H4' 5PC B 2 9.816 4.702 -5.445 1.00 0.00 H new HETATM 0 H3' 5PC B 2 8.334 3.117 -3.315 1.00 0.00 H new HETATM 0 H2' 5PC B 2 7.258 5.673 -4.617 1.00 0.00 H new HETATM 0 H1' 5PC B 2 6.488 4.534 -6.538 1.00 0.00 H new HETATM 370 P PDU B 3 8.779 5.126 -1.488 1.00 0.00 P HETATM 371 OP1 PDU B 3 9.876 5.946 -0.808 1.00 0.00 O HETATM 372 OP2 PDU B 3 8.666 3.761 -0.807 1.00 0.00 O HETATM 373 O5' PDU B 3 7.368 5.903 -1.350 1.00 0.00 O HETATM 374 C5' PDU B 3 7.139 7.213 -1.898 1.00 0.00 C HETATM 375 C4' PDU B 3 5.639 7.576 -1.862 1.00 0.00 C HETATM 376 O4' PDU B 3 4.872 6.549 -2.532 1.00 0.00 O HETATM 377 C3' PDU B 3 5.052 7.744 -0.445 1.00 0.00 C HETATM 378 O3' PDU B 3 4.219 8.920 -0.407 1.00 0.00 O HETATM 379 C2' PDU B 3 4.230 6.472 -0.251 1.00 0.00 C HETATM 380 C1' PDU B 3 3.815 6.081 -1.673 1.00 0.00 C HETATM 381 N1 PDU B 3 3.598 4.612 -1.837 1.00 0.00 N HETATM 382 C2 PDU B 3 2.323 4.101 -2.027 1.00 0.00 C HETATM 383 O2 PDU B 3 1.312 4.804 -2.037 1.00 0.00 O HETATM 384 N3 PDU B 3 2.133 2.766 -2.198 1.00 0.00 N HETATM 385 C4 PDU B 3 3.120 1.832 -2.181 1.00 0.00 C HETATM 386 O4 PDU B 3 2.830 0.645 -2.325 1.00 0.00 O HETATM 387 C5 PDU B 3 4.574 2.348 -1.972 1.00 0.00 C HETATM 388 C5A PDU B 3 5.709 1.472 -1.979 1.00 0.00 C HETATM 389 C5B PDU B 3 6.668 0.744 -1.990 1.00 0.00 C HETATM 390 C5M PDU B 3 7.787 -0.096 -2.008 1.00 0.00 C HETATM 391 C6 PDU B 3 4.761 3.679 -1.800 1.00 0.00 C HETATM 0 H5'' PDU B 3 7.709 7.951 -1.334 1.00 0.00 H new HETATM 0 H2'' PDU B 3 3.362 6.650 0.384 1.00 0.00 H new HETATM 0 H73 PDU B 3 8.017 -0.374 -3.037 1.00 0.00 H new HETATM 0 H72 PDU B 3 8.640 0.425 -1.574 1.00 0.00 H new HETATM 0 H71 PDU B 3 7.577 -0.995 -1.428 1.00 0.00 H new HETATM 0 H6 PDU B 3 5.765 4.069 -1.634 1.00 0.00 H new HETATM 0 H5' PDU B 3 7.501 7.249 -2.926 1.00 0.00 H new HETATM 0 H4' PDU B 3 5.569 8.542 -2.361 1.00 0.00 H new HETATM 0 H3' PDU B 3 5.802 7.873 0.335 1.00 0.00 H new HETATM 0 H3 PDU B 3 1.178 2.441 -2.350 1.00 0.00 H new HETATM 0 H2' PDU B 3 4.817 5.686 0.224 1.00 0.00 H new HETATM 0 H1' PDU B 3 2.854 6.532 -1.921 1.00 0.00 H new HETATM 404 P 5PC B 4 3.647 9.559 0.971 1.00 0.00 P HETATM 405 OP1 5PC B 4 3.316 11.035 0.741 1.00 0.00 O HETATM 406 OP2 5PC B 4 4.704 9.446 2.073 1.00 0.00 O HETATM 407 C5' 5PC B 4 1.043 8.984 0.772 1.00 0.00 C HETATM 408 O5' 5PC B 4 2.311 8.761 1.416 1.00 0.00 O HETATM 409 C4' 5PC B 4 0.025 7.872 1.085 1.00 0.00 C HETATM 410 O4' 5PC B 4 0.449 6.616 0.523 1.00 0.00 O HETATM 411 C3' 5PC B 4 -0.214 7.582 2.574 1.00 0.00 C HETATM 412 O3' 5PC B 4 -1.228 8.435 3.139 1.00 0.00 O HETATM 413 C2' 5PC B 4 -0.625 6.109 2.567 1.00 0.00 C HETATM 414 C1' 5PC B 4 -0.337 5.589 1.156 1.00 0.00 C HETATM 415 N1 5PC B 4 0.351 4.269 1.177 1.00 0.00 N HETATM 416 C2 5PC B 4 -0.340 3.095 0.940 1.00 0.00 C HETATM 417 O2 5PC B 4 -1.555 3.095 0.736 1.00 0.00 O HETATM 418 N3 5PC B 4 0.422 1.842 0.959 1.00 0.00 N HETATM 419 C4 5PC B 4 1.697 1.805 1.208 1.00 0.00 C HETATM 420 N4 5PC B 4 2.281 0.511 1.166 1.00 0.00 N HETATM 421 C5 5PC B 4 2.423 2.952 1.484 1.00 0.00 C HETATM 422 C6 5PC B 4 1.798 4.170 1.506 1.00 0.00 C HETATM 423 C7 5PC B 4 3.846 3.001 1.737 1.00 0.00 C HETATM 424 C8 5PC B 4 5.034 3.045 1.935 1.00 0.00 C HETATM 425 C9 5PC B 4 6.414 3.099 2.156 1.00 0.00 C HETATM 0 H5'' 5PC B 4 0.639 9.944 1.093 1.00 0.00 H new HETATM 0 H2'' 5PC B 4 -0.063 5.545 3.311 1.00 0.00 H new HETATM 0 H93 5PC B 4 6.920 2.430 1.460 1.00 0.00 H new HETATM 0 H92 5PC B 4 6.768 4.118 2.002 1.00 0.00 H new HETATM 0 H91 5PC B 4 6.631 2.790 3.179 1.00 0.00 H new HETATM 0 H6 5PC B 4 2.361 5.067 1.765 1.00 0.00 H new HETATM 0 H5' 5PC B 4 1.191 9.045 -0.306 1.00 0.00 H new HETATM 0 H42 5PC B 4 3.278 0.395 1.350 1.00 0.00 H new HETATM 0 H41 5PC B 4 1.704 -0.302 0.952 1.00 0.00 H new HETATM 0 H4' 5PC B 4 -0.896 8.262 0.652 1.00 0.00 H new HETATM 0 H3' 5PC B 4 0.660 7.777 3.196 1.00 0.00 H new HETATM 0 H2' 5PC B 4 -1.681 5.999 2.814 1.00 0.00 H new HETATM 0 H1' 5PC B 4 -1.256 5.403 0.600 1.00 0.00 H new HETATM 439 P 5PC B 5 -1.695 8.335 4.695 1.00 0.00 P HETATM 440 OP1 5PC B 5 -2.422 9.623 5.089 1.00 0.00 O HETATM 441 OP2 5PC B 5 -0.470 8.146 5.593 1.00 0.00 O HETATM 442 C5' 5PC B 5 -4.016 7.063 4.308 1.00 0.00 C HETATM 443 O5' 5PC B 5 -2.693 7.070 4.877 1.00 0.00 O HETATM 444 C4' 5PC B 5 -4.669 5.670 4.358 1.00 0.00 C HETATM 445 O4' 5PC B 5 -3.958 4.721 3.539 1.00 0.00 O HETATM 446 C3' 5PC B 5 -4.777 5.038 5.751 1.00 0.00 C HETATM 447 O3' 5PC B 5 -5.912 5.549 6.484 1.00 0.00 O HETATM 448 C2' 5PC B 5 -4.904 3.559 5.392 1.00 0.00 C HETATM 449 C1' 5PC B 5 -4.170 3.388 4.058 1.00 0.00 C HETATM 450 N1 5PC B 5 -2.882 2.645 4.183 1.00 0.00 N HETATM 451 C2 5PC B 5 -2.820 1.277 3.976 1.00 0.00 C HETATM 452 O2 5PC B 5 -3.830 0.619 3.721 1.00 0.00 O HETATM 453 N3 5PC B 5 -1.512 0.629 4.096 1.00 0.00 N HETATM 454 C4 5PC B 5 -0.439 1.279 4.430 1.00 0.00 C HETATM 455 N4 5PC B 5 0.738 0.487 4.525 1.00 0.00 N HETATM 456 C5 5PC B 5 -0.453 2.642 4.671 1.00 0.00 C HETATM 457 C6 5PC B 5 -1.626 3.345 4.572 1.00 0.00 C HETATM 458 C7 5PC B 5 0.705 3.435 5.020 1.00 0.00 C HETATM 459 C8 5PC B 5 1.670 4.100 5.301 1.00 0.00 C HETATM 460 C9 5PC B 5 2.789 4.875 5.619 1.00 0.00 C HETATM 0 H5'' 5PC B 5 -4.643 7.775 4.845 1.00 0.00 H new HETATM 0 H2'' 5PC B 5 -4.462 2.930 6.165 1.00 0.00 H new HETATM 0 H93 5PC B 5 3.596 4.653 4.920 1.00 0.00 H new HETATM 0 H92 5PC B 5 2.531 5.932 5.552 1.00 0.00 H new HETATM 0 H91 5PC B 5 3.115 4.645 6.633 1.00 0.00 H new HETATM 0 H6 5PC B 5 -1.639 4.415 4.778 1.00 0.00 H new HETATM 0 H5' 5PC B 5 -3.965 7.400 3.273 1.00 0.00 H new HETATM 0 H42 5PC B 5 1.625 0.920 4.782 1.00 0.00 H new HETATM 0 H41 5PC B 5 0.696 -0.514 4.336 1.00 0.00 H new HETATM 0 H4' 5PC B 5 -5.677 5.867 3.992 1.00 0.00 H new HETATM 0 H3' 5PC B 5 -3.941 5.250 6.417 1.00 0.00 H new HETATM 0 H2' 5PC B 5 -5.950 3.267 5.303 1.00 0.00 H new HETATM 0 H1' 5PC B 5 -4.772 2.780 3.382 1.00 0.00 H new HETATM 474 P PDU B 6 -6.505 4.853 7.828 1.00 0.00 P HETATM 475 OP1 PDU B 6 -7.372 5.856 8.591 1.00 0.00 O HETATM 476 OP2 PDU B 6 -5.353 4.386 8.724 1.00 0.00 O HETATM 477 O5' PDU B 6 -7.409 3.578 7.401 1.00 0.00 O HETATM 478 C5' PDU B 6 -7.884 2.616 8.352 1.00 0.00 C HETATM 479 C4' PDU B 6 -8.468 1.378 7.633 1.00 0.00 C HETATM 480 O4' PDU B 6 -7.499 0.846 6.699 1.00 0.00 O HETATM 481 C3' PDU B 6 -8.817 0.237 8.607 1.00 0.00 C HETATM 482 O3' PDU B 6 -9.980 -0.487 8.157 1.00 0.00 O HETATM 483 C2' PDU B 6 -7.574 -0.639 8.543 1.00 0.00 C HETATM 484 C1' PDU B 6 -7.061 -0.466 7.110 1.00 0.00 C HETATM 485 N1 PDU B 6 -5.577 -0.609 7.033 1.00 0.00 N HETATM 486 C2 PDU B 6 -4.998 -1.816 6.670 1.00 0.00 C HETATM 487 O2 PDU B 6 -5.659 -2.809 6.367 1.00 0.00 O HETATM 488 N3 PDU B 6 -3.643 -1.953 6.650 1.00 0.00 N HETATM 489 C4 PDU B 6 -2.762 -0.974 6.994 1.00 0.00 C HETATM 490 O4 PDU B 6 -1.554 -1.204 6.956 1.00 0.00 O HETATM 491 C5 PDU B 6 -3.362 0.395 7.430 1.00 0.00 C HETATM 492 C5A PDU B 6 -2.531 1.496 7.820 1.00 0.00 C HETATM 493 C5B PDU B 6 -1.837 2.426 8.141 1.00 0.00 C HETATM 494 C5M PDU B 6 -1.034 3.511 8.508 1.00 0.00 C HETATM 495 C6 PDU B 6 -4.711 0.533 7.429 1.00 0.00 C HETATM 0 H5'' PDU B 6 -7.068 2.311 9.007 1.00 0.00 H new HETATM 0 H2'' PDU B 6 -7.811 -1.681 8.758 1.00 0.00 H new HETATM 0 H73 PDU B 6 -0.403 3.797 7.667 1.00 0.00 H new HETATM 0 H72 PDU B 6 -1.666 4.353 8.790 1.00 0.00 H new HETATM 0 H71 PDU B 6 -0.406 3.230 9.353 1.00 0.00 H new HETATM 0 H6 PDU B 6 -5.161 1.482 7.719 1.00 0.00 H new HETATM 0 H5' PDU B 6 -8.647 3.069 8.984 1.00 0.00 H new HETATM 0 H4' PDU B 6 -9.375 1.718 7.133 1.00 0.00 H new HETATM 0 H3' PDU B 6 -9.058 0.580 9.613 1.00 0.00 H new HETATM 0 H3 PDU B 6 -3.262 -2.852 6.357 1.00 0.00 H new HETATM 0 H2' PDU B 6 -6.828 -0.325 9.273 1.00 0.00 H new HETATM 0 H1' PDU B 6 -7.453 -1.239 6.449 1.00 0.00 H new HETATM 508 P PDU B 7 -10.784 -1.526 9.114 1.00 0.00 P HETATM 509 OP1 PDU B 7 -12.123 -1.885 8.465 1.00 0.00 O HETATM 510 OP2 PDU B 7 -11.042 -0.875 10.474 1.00 0.00 O HETATM 511 O5' PDU B 7 -9.905 -2.872 9.325 1.00 0.00 O HETATM 512 C5' PDU B 7 -9.744 -3.852 8.282 1.00 0.00 C HETATM 513 C4' PDU B 7 -8.627 -4.866 8.600 1.00 0.00 C HETATM 514 O4' PDU B 7 -7.337 -4.231 8.552 1.00 0.00 O HETATM 515 C3' PDU B 7 -8.720 -5.565 9.975 1.00 0.00 C HETATM 516 O3' PDU B 7 -8.980 -6.955 9.811 1.00 0.00 O HETATM 517 C2' PDU B 7 -7.338 -5.357 10.601 1.00 0.00 C HETATM 518 C1' PDU B 7 -6.456 -4.971 9.409 1.00 0.00 C HETATM 519 N1 PDU B 7 -5.245 -4.170 9.757 1.00 0.00 N HETATM 520 C2 PDU B 7 -3.976 -4.669 9.501 1.00 0.00 C HETATM 521 O2 PDU B 7 -3.776 -5.805 9.070 1.00 0.00 O HETATM 522 N3 PDU B 7 -2.876 -3.902 9.719 1.00 0.00 N HETATM 523 C4 PDU B 7 -2.895 -2.624 10.178 1.00 0.00 C HETATM 524 O4 PDU B 7 -1.832 -2.026 10.338 1.00 0.00 O HETATM 525 C5 PDU B 7 -4.296 -2.003 10.464 1.00 0.00 C HETATM 526 C5A PDU B 7 -4.432 -0.633 10.864 1.00 0.00 C HETATM 527 C5B PDU B 7 -4.547 0.522 11.188 1.00 0.00 C HETATM 528 C5M PDU B 7 -4.682 1.866 11.552 1.00 0.00 C HETATM 529 C6 PDU B 7 -5.394 -2.781 10.279 1.00 0.00 C HETATM 0 HO3' PDU B 7 -9.034 -7.384 10.691 1.00 0.00 H new HETATM 0 H5'' PDU B 7 -10.684 -4.384 8.138 1.00 0.00 H new HETATM 0 H2'' PDU B 7 -6.978 -6.263 11.089 1.00 0.00 H new HETATM 0 H73 PDU B 7 -3.899 2.453 11.073 1.00 0.00 H new HETATM 0 H72 PDU B 7 -5.657 2.233 11.233 1.00 0.00 H new HETATM 0 H71 PDU B 7 -4.596 1.960 12.634 1.00 0.00 H new HETATM 0 H6 PDU B 7 -6.384 -2.390 10.512 1.00 0.00 H new HETATM 0 H5' PDU B 7 -9.517 -3.347 7.343 1.00 0.00 H new HETATM 0 H4' PDU B 7 -8.759 -5.629 7.833 1.00 0.00 H new HETATM 0 H3' PDU B 7 -9.525 -5.164 10.591 1.00 0.00 H new HETATM 0 H3 PDU B 7 -1.966 -4.318 9.523 1.00 0.00 H new HETATM 0 H2' PDU B 7 -7.355 -4.573 11.358 1.00 0.00 H new HETATM 0 H1' PDU B 7 -6.034 -5.864 8.948 1.00 0.00 H new TER 543 PDU B 7 CONECT 302 303 304 321 322 CONECT 303 302 CONECT 304 302 305 306 323 CONECT 305 304 309 CONECT 306 304 307 308 324 CONECT 307 306 335 CONECT 308 306 309 325 326 CONECT 309 305 308 310 327 CONECT 310 309 311 317 CONECT 311 310 312 313 CONECT 312 311 CONECT 313 311 314 CONECT 314 313 315 316 CONECT 315 314 328 329 CONECT 316 314 317 318 CONECT 317 310 316 330 CONECT 318 316 319 CONECT 319 318 320 CONECT 320 319 331 332 333 CONECT 321 302 CONECT 322 302 CONECT 323 304 CONECT 324 306 CONECT 325 308 CONECT 326 308 CONECT 327 309 CONECT 328 315 CONECT 329 315 CONECT 330 317 CONECT 331 320 CONECT 332 320 CONECT 333 320 CONECT 335 307 336 337 339 CONECT 336 335 CONECT 337 335 CONECT 338 339 340 357 358 CONECT 339 335 338 CONECT 340 338 341 342 359 CONECT 341 340 345 CONECT 342 340 343 344 360 CONECT 343 342 370 CONECT 344 342 345 361 362 CONECT 345 341 344 346 363 CONECT 346 345 347 353 CONECT 347 346 348 349 CONECT 348 347 CONECT 349 347 350 CONECT 350 349 351 352 CONECT 351 350 364 365 CONECT 352 350 353 354 CONECT 353 346 352 366 CONECT 354 352 355 CONECT 355 354 356 CONECT 356 355 367 368 369 CONECT 357 338 CONECT 358 338 CONECT 359 340 CONECT 360 342 CONECT 361 344 CONECT 362 344 CONECT 363 345 CONECT 364 351 CONECT 365 351 CONECT 366 353 CONECT 367 356 CONECT 368 356 CONECT 369 356 CONECT 370 343 371 372 373 CONECT 371 370 CONECT 372 370 CONECT 373 370 374 CONECT 374 373 375 392 393 CONECT 375 374 376 377 394 CONECT 376 375 380 CONECT 377 375 378 379 395 CONECT 378 377 404 CONECT 379 377 380 396 397 CONECT 380 376 379 381 398 CONECT 381 380 382 391 CONECT 382 381 383 384 CONECT 383 382 CONECT 384 382 385 399 CONECT 385 384 386 387 CONECT 386 385 CONECT 387 385 388 391 CONECT 388 387 389 CONECT 389 388 390 CONECT 390 389 400 401 402 CONECT 391 381 387 403 CONECT 392 374 CONECT 393 374 CONECT 394 375 CONECT 395 377 CONECT 396 379 CONECT 397 379 CONECT 398 380 CONECT 399 384 CONECT 400 390 CONECT 401 390 CONECT 402 390 CONECT 403 391 CONECT 404 378 405 406 408 CONECT 405 404 CONECT 406 404 CONECT 407 408 409 426 427 CONECT 408 404 407 CONECT 409 407 410 411 428 CONECT 410 409 414 CONECT 411 409 412 413 429 CONECT 412 411 439 CONECT 413 411 414 430 431 CONECT 414 410 413 415 432 CONECT 415 414 416 422 CONECT 416 415 417 418 CONECT 417 416 CONECT 418 416 419 CONECT 419 418 420 421 CONECT 420 419 433 434 CONECT 421 419 422 423 CONECT 422 415 421 435 CONECT 423 421 424 CONECT 424 423 425 CONECT 425 424 436 437 438 CONECT 426 407 CONECT 427 407 CONECT 428 409 CONECT 429 411 CONECT 430 413 CONECT 431 413 CONECT 432 414 CONECT 433 420 CONECT 434 420 CONECT 435 422 CONECT 436 425 CONECT 437 425 CONECT 438 425 CONECT 439 412 440 441 443 CONECT 440 439 CONECT 441 439 CONECT 442 443 444 461 462 CONECT 443 439 442 CONECT 444 442 445 446 463 CONECT 445 444 449 CONECT 446 444 447 448 464 CONECT 447 446 474 CONECT 448 446 449 465 466 CONECT 449 445 448 450 467 CONECT 450 449 451 457 CONECT 451 450 452 453 CONECT 452 451 CONECT 453 451 454 CONECT 454 453 455 456 CONECT 455 454 468 469 CONECT 456 454 457 458 CONECT 457 450 456 470 CONECT 458 456 459 CONECT 459 458 460 CONECT 460 459 471 472 473 CONECT 461 442 CONECT 462 442 CONECT 463 444 CONECT 464 446 CONECT 465 448 CONECT 466 448 CONECT 467 449 CONECT 468 455 CONECT 469 455 CONECT 470 457 CONECT 471 460 CONECT 472 460 CONECT 473 460 CONECT 474 447 475 476 477 CONECT 475 474 CONECT 476 474 CONECT 477 474 478 CONECT 478 477 479 496 497 CONECT 479 478 480 481 498 CONECT 480 479 484 CONECT 481 479 482 483 499 CONECT 482 481 508 CONECT 483 481 484 500 501 CONECT 484 480 483 485 502 CONECT 485 484 486 495 CONECT 486 485 487 488 CONECT 487 486 CONECT 488 486 489 503 CONECT 489 488 490 491 CONECT 490 489 CONECT 491 489 492 495 CONECT 492 491 493 CONECT 493 492 494 CONECT 494 493 504 505 506 CONECT 495 485 491 507 CONECT 496 478 CONECT 497 478 CONECT 498 479 CONECT 499 481 CONECT 500 483 CONECT 501 483 CONECT 502 484 CONECT 503 488 CONECT 504 494 CONECT 505 494 CONECT 506 494 CONECT 507 495 CONECT 508 482 509 510 511 CONECT 509 508 CONECT 510 508 CONECT 511 508 512 CONECT 512 511 513 530 531 CONECT 513 512 514 515 532 CONECT 514 513 518 CONECT 515 513 516 517 533 CONECT 516 515 534 CONECT 517 515 518 535 536 CONECT 518 514 517 519 537 CONECT 519 518 520 529 CONECT 520 519 521 522 CONECT 521 520 CONECT 522 520 523 538 CONECT 523 522 524 525 CONECT 524 523 CONECT 525 523 526 529 CONECT 526 525 527 CONECT 527 526 528 CONECT 528 527 539 540 541 CONECT 529 519 525 542 CONECT 530 512 CONECT 531 512 CONECT 532 513 CONECT 533 515 CONECT 534 516 CONECT 535 517 CONECT 536 517 CONECT 537 518 CONECT 538 522 CONECT 539 528 CONECT 540 528 CONECT 541 528 CONECT 542 529 END