HEADER DNA 20-DEC-13 2MIW TITLE NUCLEAR MAGNETIC RESONANCE STUDIES OF N2-GUANINE ADDUCTS DERIVED FROM TITLE 2 THE TUMORIGEN DIBENZO[A,L]PYRENE IN DNA: IMPACT OF ADDUCT TITLE 3 STEREOCHEMISTRY, SIZE, AND LOCAL DNA STRUCTURE ON SOLUTION TITLE 4 CONFORMATIONS COMPND MOL_ID: 1; COMPND 2 MOLECULE: DNA_(5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3'); COMPND 3 CHAIN: A; COMPND 4 ENGINEERED: YES; COMPND 5 MOL_ID: 2; COMPND 6 MOLECULE: DNA_(5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3'); COMPND 7 CHAIN: B; COMPND 8 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 SYNTHETIC: YES; SOURCE 3 MOL_ID: 2; SOURCE 4 SYNTHETIC: YES KEYWDS DNA, 14S (-)-TRANS-ANTI-DB[A,L]P-N2-DG, DNA ADDUCT EXPDTA SOLUTION NMR AUTHOR F.A.RODRIGUEZ,Z.LIU,C.H.LIN,S.DING,Y.CAI,A.KOLBANOVSKIY, AUTHOR 2 M.KOLBANOVSKIY,S.AMIN,S.BROYDE,N.E.GEACINTOV REVDAT 2 09-APR-14 2MIW 1 JRNL REVDAT 1 02-APR-14 2MIW 0 JRNL AUTH F.A.RODRIGUEZ,Z.LIU,C.H.LIN,S.DING,Y.CAI,A.KOLBANOVSKIY, JRNL AUTH 2 M.KOLBANOVSKIY,S.AMIN,S.BROYDE,N.E.GEACINTOV JRNL TITL NUCLEAR MAGNETIC RESONANCE STUDIES OF AN N(2)-GUANINE ADDUCT JRNL TITL 2 DERIVED FROM THE TUMORIGEN DIBENZO[A,L]PYRENE IN DNA: IMPACT JRNL TITL 3 OF ADDUCT STEREOCHEMISTRY, SIZE, AND LOCAL DNA SEQUENCE ON JRNL TITL 4 SOLUTION CONFORMATIONS. JRNL REF BIOCHEMISTRY V. 53 1827 2014 JRNL REFN ISSN 0006-2960 JRNL PMID 24617538 JRNL DOI 10.1021/BI4017044 REMARK 2 REMARK 2 RESOLUTION. NOT APPLICABLE. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : AMBER REMARK 3 AUTHORS : CASE, DARDEN, CHEATHAM, III, SIMMERLING, WANG, REMARK 3 DUKE, LUO, ... AND KOLLMAN REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: NULL REMARK 4 REMARK 4 2MIW COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 09-JAN-14. REMARK 100 THE RCSB ID CODE IS RCSB103666. REMARK 210 REMARK 210 EXPERIMENTAL DETAILS REMARK 210 EXPERIMENT TYPE : NMR REMARK 210 TEMPERATURE (KELVIN) : NULL REMARK 210 PH : 6.8 REMARK 210 IONIC STRENGTH : NULL REMARK 210 PRESSURE : NULL REMARK 210 SAMPLE CONTENTS : 1.5 MM DB[A,L]P COVALENTLY BOUND REMARK 210 TO 11MER DNA DUPLEX, 100 MM NACL, REMARK 210 10 MM NA2HPO4, 25 MM DSS, 100% REMARK 210 D2O; 1.5 MM DB[A,L]P COVALENTLY REMARK 210 BOUND TO 11MER DNA DUPLEX, 100 MM REMARK 210 NACL, 10 MM NA2HPO4, 25 MM DSS, REMARK 210 90% H2O/10% D2O REMARK 210 REMARK 210 NMR EXPERIMENTS CONDUCTED : 2D 1H-1H NOESY; 2D 1H-1H TOCSY REMARK 210 SPECTROMETER FIELD STRENGTH : 500 MHZ REMARK 210 SPECTROMETER MODEL : AVANCE REMARK 210 SPECTROMETER MANUFACTURER : BRUKER REMARK 210 REMARK 210 STRUCTURE DETERMINATION. REMARK 210 SOFTWARE USED : TOPSPIN, SPARKY REMARK 210 METHOD USED : MOLECULAR DYNAMICS REMARK 210 REMARK 210 CONFORMERS, NUMBER CALCULATED : 1000 REMARK 210 CONFORMERS, NUMBER SUBMITTED : 1 REMARK 210 CONFORMERS, SELECTION CRITERIA : STRUCTURES WITH THE LEAST REMARK 210 RESTRAINT VIOLATIONS REMARK 210 REMARK 210 BEST REPRESENTATIVE CONFORMER IN THIS ENSEMBLE : 1 REMARK 210 REMARK 210 REMARK: NULL REMARK 215 REMARK 215 NMR STUDY REMARK 215 THE COORDINATES IN THIS ENTRY WERE GENERATED FROM SOLUTION REMARK 215 NMR DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE THAT REMARK 215 CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES ON REMARK 215 THESE RECORDS ARE MEANINGLESS. REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: DIMERIC REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND LENGTHS REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,2(A3,1X,A1,I4,A1,1X,A4,3X),1X,F6.3) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 RES CSSEQI ATM2 DEVIATION REMARK 500 DC A 1 O4' DC A 1 C4' -0.073 REMARK 500 DC A 2 C2 DC A 2 O2 -0.068 REMARK 500 DC A 2 C4 DC A 2 N4 -0.063 REMARK 500 DT A 4 C3' DT A 4 C2' -0.080 REMARK 500 DC A 5 P DC A 5 O5' -0.072 REMARK 500 DC A 5 C4 DC A 5 N4 -0.062 REMARK 500 DC A 5 C2 DC A 5 N3 0.064 REMARK 500 DC A 5 C5 DC A 5 C6 0.055 REMARK 500 DG A 6 O3' DG A 6 C3' -0.038 REMARK 500 DC A 7 C4' DC A 7 C3' 0.064 REMARK 500 DT A 8 P DT A 8 O5' 0.072 REMARK 500 DT A 8 C5' DT A 8 C4' 0.046 REMARK 500 DT A 8 C3' DT A 8 C2' -0.063 REMARK 500 DT A 8 C6 DT A 8 N1 0.073 REMARK 500 DA A 9 C5' DA A 9 C4' 0.054 REMARK 500 DC A 10 C3' DC A 10 C2' -0.063 REMARK 500 DC A 10 C4 DC A 10 N4 -0.061 REMARK 500 DG B 12 N1 DG B 12 C2 -0.060 REMARK 500 DG B 12 C2 DG B 12 N3 0.064 REMARK 500 DG B 12 C5 DG B 12 C6 0.079 REMARK 500 DG B 12 C2 DG B 12 N2 -0.071 REMARK 500 DG B 13 C5' DG B 13 C4' 0.046 REMARK 500 DG B 13 C6 DG B 13 N1 -0.060 REMARK 500 DG B 13 N7 DG B 13 C8 -0.044 REMARK 500 DA B 15 C5' DA B 15 C4' 0.069 REMARK 500 DA B 15 N7 DA B 15 C8 -0.082 REMARK 500 DG B 16 N3 DG B 16 C4 0.055 REMARK 500 DC B 17 N3 DC B 17 C4 -0.046 REMARK 500 DG B 18 O4' DG B 18 C4' -0.069 REMARK 500 DA B 19 C4' DA B 19 C3' 0.078 REMARK 500 DT B 20 C5 DT B 20 C7 0.066 REMARK 500 DG B 21 C6 DG B 21 N1 -0.088 REMARK 500 DG B 22 C5' DG B 22 C4' 0.046 REMARK 500 DG B 22 O3' DG B 22 C3' -0.038 REMARK 500 DG B 22 N9 DG B 22 C4 0.050 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND ANGLES REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3 REMARK 500 DC A 1 O4' - C1' - N1 ANGL. DEV. = 7.3 DEGREES REMARK 500 DC A 1 C2 - N3 - C4 ANGL. DEV. = -6.7 DEGREES REMARK 500 DC A 1 N3 - C4 - C5 ANGL. DEV. = 4.8 DEGREES REMARK 500 DC A 1 C5 - C6 - N1 ANGL. DEV. = -3.5 DEGREES REMARK 500 DC A 1 N3 - C2 - O2 ANGL. DEV. = -4.5 DEGREES REMARK 500 DC A 1 C5 - C4 - N4 ANGL. DEV. = -5.3 DEGREES REMARK 500 DC A 2 C1' - O4' - C4' ANGL. DEV. = -9.6 DEGREES REMARK 500 DC A 2 O4' - C1' - N1 ANGL. DEV. = 2.3 DEGREES REMARK 500 DA A 3 C6 - N1 - C2 ANGL. DEV. = 3.9 DEGREES REMARK 500 DA A 3 C4 - C5 - C6 ANGL. DEV. = -5.1 DEGREES REMARK 500 DA A 3 N7 - C8 - N9 ANGL. DEV. = 4.7 DEGREES REMARK 500 DA A 3 C8 - N9 - C4 ANGL. DEV. = -3.3 DEGREES REMARK 500 DA A 3 C6 - C5 - N7 ANGL. DEV. = 5.3 DEGREES REMARK 500 DT A 4 O4' - C4' - C3' ANGL. DEV. = 5.4 DEGREES REMARK 500 DT A 4 O4' - C1' - N1 ANGL. DEV. = 1.8 DEGREES REMARK 500 DT A 4 C6 - N1 - C2 ANGL. DEV. = -3.9 DEGREES REMARK 500 DT A 4 N3 - C2 - O2 ANGL. DEV. = -5.3 DEGREES REMARK 500 DA A 3 C3' - O3' - P ANGL. DEV. = 7.5 DEGREES REMARK 500 DC A 5 C3' - C2' - C1' ANGL. DEV. = -9.1 DEGREES REMARK 500 DC A 5 O4' - C1' - N1 ANGL. DEV. = 13.6 DEGREES REMARK 500 DG A 6 O4' - C4' - C3' ANGL. DEV. = -7.2 DEGREES REMARK 500 DG A 6 O4' - C1' - N9 ANGL. DEV. = 8.1 DEGREES REMARK 500 DG A 6 N3 - C2 - N2 ANGL. DEV. = 7.0 DEGREES REMARK 500 DC A 7 O4' - C1' - C2' ANGL. DEV. = -5.6 DEGREES REMARK 500 DC A 7 C2 - N3 - C4 ANGL. DEV. = -4.7 DEGREES REMARK 500 DC A 7 C5 - C6 - N1 ANGL. DEV. = -3.6 DEGREES REMARK 500 DC A 7 N3 - C4 - N4 ANGL. DEV. = -4.4 DEGREES REMARK 500 DT A 8 C1' - O4' - C4' ANGL. DEV. = -7.1 DEGREES REMARK 500 DT A 8 N1 - C2 - N3 ANGL. DEV. = 5.4 DEGREES REMARK 500 DT A 8 C4 - C5 - C6 ANGL. DEV. = 7.3 DEGREES REMARK 500 DT A 8 C5 - C6 - N1 ANGL. DEV. = -6.0 DEGREES REMARK 500 DT A 8 N3 - C2 - O2 ANGL. DEV. = -7.9 DEGREES REMARK 500 DT A 8 C6 - C5 - C7 ANGL. DEV. = -7.1 DEGREES REMARK 500 DA A 9 C4' - C3' - C2' ANGL. DEV. = 5.8 DEGREES REMARK 500 DA A 9 O4' - C1' - N9 ANGL. DEV. = 5.8 DEGREES REMARK 500 DA A 9 C4 - C5 - C6 ANGL. DEV. = -3.1 DEGREES REMARK 500 DA A 9 N1 - C6 - N6 ANGL. DEV. = -13.4 DEGREES REMARK 500 DA A 9 C5 - C6 - N6 ANGL. DEV. = 8.9 DEGREES REMARK 500 DC A 10 O4' - C1' - N1 ANGL. DEV. = 10.4 DEGREES REMARK 500 DC A 10 C2 - N3 - C4 ANGL. DEV. = -3.8 DEGREES REMARK 500 DC A 10 N3 - C4 - C5 ANGL. DEV. = 3.0 DEGREES REMARK 500 DC A 10 N1 - C2 - O2 ANGL. DEV. = 4.8 DEGREES REMARK 500 DC A 10 N3 - C4 - N4 ANGL. DEV. = -8.8 DEGREES REMARK 500 DC A 11 O4' - C4' - C3' ANGL. DEV. = -2.9 DEGREES REMARK 500 DC A 11 O4' - C1' - C2' ANGL. DEV. = -6.0 DEGREES REMARK 500 DC A 11 O4' - C1' - N1 ANGL. DEV. = 9.1 DEGREES REMARK 500 DC A 11 N1 - C2 - O2 ANGL. DEV. = 5.6 DEGREES REMARK 500 DG B 12 O4' - C1' - N9 ANGL. DEV. = 10.1 DEGREES REMARK 500 DG B 12 N3 - C4 - C5 ANGL. DEV. = -4.3 DEGREES REMARK 500 DG B 12 N7 - C8 - N9 ANGL. DEV. = -3.1 DEGREES REMARK 500 REMARK 500 THIS ENTRY HAS 104 ANGLE DEVIATIONS. REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: PLANAR GROUPS REMARK 500 REMARK 500 PLANAR GROUPS IN THE FOLLOWING RESIDUES HAVE A TOTAL REMARK 500 RMS DISTANCE OF ALL ATOMS FROM THE BEST-FIT PLANE REMARK 500 BY MORE THAN AN EXPECTED VALUE OF 6*RMSD, WITH AN REMARK 500 RMSD 0.02 ANGSTROMS, OR AT LEAST ONE ATOM HAS REMARK 500 AN RMSD GREATER THAN THIS VALUE REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 M RES CSSEQI RMS TYPE REMARK 500 DT A 4 0.09 SIDE CHAIN REMARK 500 DG A 6 0.13 SIDE CHAIN REMARK 500 DC A 7 0.11 SIDE CHAIN REMARK 500 DT A 8 0.07 SIDE CHAIN REMARK 500 DA A 9 0.14 SIDE CHAIN REMARK 500 DC A 10 0.08 SIDE CHAIN REMARK 500 DC A 11 0.08 SIDE CHAIN REMARK 500 DG B 12 0.08 SIDE CHAIN REMARK 500 DG B 13 0.07 SIDE CHAIN REMARK 500 DT B 14 0.07 SIDE CHAIN REMARK 500 DA B 15 0.06 SIDE CHAIN REMARK 500 DG B 16 0.13 SIDE CHAIN REMARK 500 DC B 17 0.11 SIDE CHAIN REMARK 500 DG B 18 0.11 SIDE CHAIN REMARK 500 DA B 19 0.13 SIDE CHAIN REMARK 500 DG B 22 0.14 SIDE CHAIN REMARK 500 REMARK 500 REMARK: NULL REMARK 800 REMARK 800 SITE REMARK 800 SITE_IDENTIFIER: AC1 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE 2QL A 101 REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 19696 RELATED DB: BMRB REMARK 900 RELATED ID: 2MIV RELATED DB: PDB DBREF 2MIW A 1 11 PDB 2MIW 2MIW 1 11 DBREF 2MIW B 12 22 PDB 2MIW 2MIW 12 22 SEQRES 1 A 11 DC DC DA DT DC DG DC DT DA DC DC SEQRES 1 B 11 DG DG DT DA DG DC DG DA DT DG DG HET 2QL A 101 44 HETNAM 2QL (11R,12R,13R)-11,12,13,14-TETRAHYDRONAPHTHO[1,2,3,4- HETNAM 2 2QL PQR]TETRAPHENE-11,12,13-TRIOL FORMUL 3 2QL C24 H18 O3 LINK C14 2QL A 101 N2 DG A 6 1555 1555 1.47 SITE 1 AC1 6 DC A 5 DG A 6 DC A 7 DG B 16 SITE 2 AC1 6 DC B 17 DG B 18 CRYST1 1.000 1.000 1.000 90.00 90.00 90.00 P 1 1 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 1.000000 0.000000 0.000000 0.00000 SCALE2 0.000000 1.000000 0.000000 0.00000 SCALE3 0.000000 0.000000 1.000000 0.00000 ATOM 1 O5' DC A 1 17.639 0.187 10.793 1.00 0.00 O ATOM 2 C5' DC A 1 18.085 -0.922 11.584 1.00 0.00 C ATOM 3 C4' DC A 1 16.976 -1.568 12.321 1.00 0.00 C ATOM 4 O4' DC A 1 16.275 -0.729 13.151 1.00 0.00 O ATOM 5 C3' DC A 1 15.873 -2.090 11.328 1.00 0.00 C ATOM 6 O3' DC A 1 15.845 -3.481 11.428 1.00 0.00 O ATOM 7 C2' DC A 1 14.500 -1.563 11.806 1.00 0.00 C ATOM 8 C1' DC A 1 14.869 -1.106 13.193 1.00 0.00 C ATOM 9 N1 DC A 1 13.934 -0.086 13.823 1.00 0.00 N ATOM 10 C2 DC A 1 12.952 -0.433 14.812 1.00 0.00 C ATOM 11 O2 DC A 1 12.818 -1.588 15.188 1.00 0.00 O ATOM 12 N3 DC A 1 12.112 0.512 15.358 1.00 0.00 N ATOM 13 C4 DC A 1 12.330 1.761 14.877 1.00 0.00 C ATOM 14 N4 DC A 1 11.748 2.747 15.462 1.00 0.00 N ATOM 15 C5 DC A 1 13.241 2.126 13.867 1.00 0.00 C ATOM 16 C6 DC A 1 14.117 1.197 13.418 1.00 0.00 C ATOM 17 H5' DC A 1 18.872 -0.570 12.250 1.00 0.00 H ATOM 18 H5'' DC A 1 18.417 -1.676 10.870 1.00 0.00 H ATOM 19 H4' DC A 1 17.271 -2.436 12.909 1.00 0.00 H ATOM 20 H3' DC A 1 16.074 -1.824 10.290 1.00 0.00 H ATOM 21 H2' DC A 1 14.285 -0.661 11.234 1.00 0.00 H ATOM 22 H2'' DC A 1 13.637 -2.229 11.801 1.00 0.00 H ATOM 23 H1' DC A 1 14.839 -1.972 13.854 1.00 0.00 H ATOM 24 H41 DC A 1 12.221 3.636 15.375 1.00 0.00 H ATOM 25 H42 DC A 1 11.122 2.468 16.203 1.00 0.00 H ATOM 26 H5 DC A 1 13.320 3.135 13.491 1.00 0.00 H ATOM 27 H6 DC A 1 14.909 1.378 12.707 1.00 0.00 H ATOM 28 HO5' DC A 1 17.676 0.999 11.304 1.00 0.00 H ATOM 29 P DC A 2 15.112 -4.414 10.301 1.00 0.00 P ATOM 30 OP1 DC A 2 15.876 -5.671 10.426 1.00 0.00 O ATOM 31 OP2 DC A 2 15.107 -3.719 8.991 1.00 0.00 O ATOM 32 O5' DC A 2 13.609 -4.785 10.834 1.00 0.00 O ATOM 33 C5' DC A 2 13.383 -5.485 12.092 1.00 0.00 C ATOM 34 C4' DC A 2 12.025 -5.161 12.729 1.00 0.00 C ATOM 35 O4' DC A 2 11.929 -3.720 12.784 1.00 0.00 O ATOM 36 C3' DC A 2 10.817 -5.562 11.841 1.00 0.00 C ATOM 37 O3' DC A 2 10.191 -6.759 12.367 1.00 0.00 O ATOM 38 C2' DC A 2 9.917 -4.307 11.815 1.00 0.00 C ATOM 39 C1' DC A 2 10.490 -3.557 12.975 1.00 0.00 C ATOM 40 N1 DC A 2 10.110 -2.095 12.929 1.00 0.00 N ATOM 41 C2 DC A 2 9.226 -1.559 13.905 1.00 0.00 C ATOM 42 O2 DC A 2 8.717 -2.255 14.699 1.00 0.00 O ATOM 43 N3 DC A 2 8.950 -0.243 13.886 1.00 0.00 N ATOM 44 C4 DC A 2 9.498 0.534 12.981 1.00 0.00 C ATOM 45 N4 DC A 2 9.003 1.705 12.937 1.00 0.00 N ATOM 46 C5 DC A 2 10.482 0.031 12.033 1.00 0.00 C ATOM 47 C6 DC A 2 10.695 -1.294 12.010 1.00 0.00 C ATOM 48 H5' DC A 2 14.067 -5.217 12.898 1.00 0.00 H ATOM 49 H5'' DC A 2 13.316 -6.550 11.869 1.00 0.00 H ATOM 50 H4' DC A 2 11.827 -5.569 13.720 1.00 0.00 H ATOM 51 H3' DC A 2 11.110 -5.762 10.810 1.00 0.00 H ATOM 52 H2' DC A 2 10.113 -3.834 10.852 1.00 0.00 H ATOM 53 H2'' DC A 2 8.836 -4.429 11.889 1.00 0.00 H ATOM 54 H1' DC A 2 10.165 -4.084 13.871 1.00 0.00 H ATOM 55 H41 DC A 2 9.345 2.334 12.225 1.00 0.00 H ATOM 56 H42 DC A 2 8.453 2.121 13.675 1.00 0.00 H ATOM 57 H5 DC A 2 10.968 0.648 11.291 1.00 0.00 H ATOM 58 H6 DC A 2 11.481 -1.669 11.371 1.00 0.00 H ATOM 59 P DA A 3 9.333 -7.731 11.467 1.00 0.00 P ATOM 60 OP1 DA A 3 9.202 -9.038 12.153 1.00 0.00 O ATOM 61 OP2 DA A 3 9.754 -7.606 10.103 1.00 0.00 O ATOM 62 O5' DA A 3 7.913 -6.940 11.659 1.00 0.00 O ATOM 63 C5' DA A 3 7.091 -7.050 12.763 1.00 0.00 C ATOM 64 C4' DA A 3 5.731 -6.390 12.619 1.00 0.00 C ATOM 65 O4' DA A 3 5.781 -4.961 12.970 1.00 0.00 O ATOM 66 C3' DA A 3 5.080 -6.481 11.244 1.00 0.00 C ATOM 67 O3' DA A 3 3.827 -7.191 11.515 1.00 0.00 O ATOM 68 C2' DA A 3 5.024 -4.993 10.803 1.00 0.00 C ATOM 69 C1' DA A 3 4.885 -4.298 12.138 1.00 0.00 C ATOM 70 N9 DA A 3 5.478 -2.922 11.978 1.00 0.00 N ATOM 71 C8 DA A 3 6.602 -2.486 11.275 1.00 0.00 C ATOM 72 N7 DA A 3 6.958 -1.264 11.391 1.00 0.00 N ATOM 73 C5 DA A 3 5.878 -0.718 12.098 1.00 0.00 C ATOM 74 C6 DA A 3 5.429 0.582 12.510 1.00 0.00 C ATOM 75 N6 DA A 3 6.062 1.693 12.283 1.00 0.00 N ATOM 76 N1 DA A 3 4.288 0.682 13.185 1.00 0.00 N ATOM 77 C2 DA A 3 3.569 -0.350 13.494 1.00 0.00 C ATOM 78 N3 DA A 3 3.822 -1.618 13.207 1.00 0.00 N ATOM 79 C4 DA A 3 4.977 -1.745 12.503 1.00 0.00 C ATOM 80 H5' DA A 3 7.659 -6.534 13.537 1.00 0.00 H ATOM 81 H5'' DA A 3 7.061 -8.075 13.131 1.00 0.00 H ATOM 82 H4' DA A 3 5.154 -6.971 13.339 1.00 0.00 H ATOM 83 H3' DA A 3 5.744 -6.984 10.543 1.00 0.00 H ATOM 84 H2' DA A 3 5.953 -4.782 10.273 1.00 0.00 H ATOM 85 H2'' DA A 3 4.106 -4.860 10.231 1.00 0.00 H ATOM 86 H1' DA A 3 3.846 -4.269 12.465 1.00 0.00 H ATOM 87 H8 DA A 3 7.332 -3.147 10.830 1.00 0.00 H ATOM 88 H61 DA A 3 5.621 2.558 12.563 1.00 0.00 H ATOM 89 H62 DA A 3 6.950 1.629 11.808 1.00 0.00 H ATOM 90 H2 DA A 3 2.617 -0.059 13.914 1.00 0.00 H ATOM 91 P DT A 4 2.781 -7.800 10.418 1.00 0.00 P ATOM 92 OP1 DT A 4 1.883 -8.761 11.143 1.00 0.00 O ATOM 93 OP2 DT A 4 3.605 -8.334 9.340 1.00 0.00 O ATOM 94 O5' DT A 4 2.071 -6.557 9.734 1.00 0.00 O ATOM 95 C5' DT A 4 0.908 -5.941 10.289 1.00 0.00 C ATOM 96 C4' DT A 4 0.584 -4.563 9.783 1.00 0.00 C ATOM 97 O4' DT A 4 1.548 -3.601 10.068 1.00 0.00 O ATOM 98 C3' DT A 4 0.177 -4.520 8.332 1.00 0.00 C ATOM 99 O3' DT A 4 -1.148 -3.952 8.375 1.00 0.00 O ATOM 100 C2' DT A 4 1.106 -3.560 7.804 1.00 0.00 C ATOM 101 C1' DT A 4 1.445 -2.643 8.960 1.00 0.00 C ATOM 102 N1 DT A 4 2.731 -1.959 8.762 1.00 0.00 N ATOM 103 C2 DT A 4 2.903 -0.767 9.472 1.00 0.00 C ATOM 104 O2 DT A 4 2.068 -0.229 10.172 1.00 0.00 O ATOM 105 N3 DT A 4 4.116 -0.066 9.262 1.00 0.00 N ATOM 106 C4 DT A 4 5.115 -0.469 8.406 1.00 0.00 C ATOM 107 O4 DT A 4 6.043 0.323 8.132 1.00 0.00 O ATOM 108 C5 DT A 4 4.975 -1.787 7.872 1.00 0.00 C ATOM 109 C7 DT A 4 6.111 -2.431 7.079 1.00 0.00 C ATOM 110 C6 DT A 4 3.803 -2.440 8.076 1.00 0.00 C ATOM 111 H5' DT A 4 1.143 -5.872 11.352 1.00 0.00 H ATOM 112 H5'' DT A 4 -0.040 -6.461 10.149 1.00 0.00 H ATOM 113 H4' DT A 4 -0.299 -4.193 10.304 1.00 0.00 H ATOM 114 H3' DT A 4 0.247 -5.453 7.773 1.00 0.00 H ATOM 115 H2' DT A 4 1.982 -4.081 7.415 1.00 0.00 H ATOM 116 H2'' DT A 4 0.603 -2.983 7.029 1.00 0.00 H ATOM 117 H1' DT A 4 0.610 -1.942 8.963 1.00 0.00 H ATOM 118 H3 DT A 4 4.257 0.757 9.829 1.00 0.00 H ATOM 119 H71 DT A 4 7.113 -2.082 7.329 1.00 0.00 H ATOM 120 H72 DT A 4 6.007 -3.508 7.201 1.00 0.00 H ATOM 121 H73 DT A 4 6.069 -2.260 6.003 1.00 0.00 H ATOM 122 H6 DT A 4 3.755 -3.457 7.715 1.00 0.00 H ATOM 123 P DC A 5 -2.520 -4.789 8.202 1.00 0.00 P ATOM 124 OP1 DC A 5 -3.613 -3.811 8.184 1.00 0.00 O ATOM 125 OP2 DC A 5 -2.446 -5.939 9.182 1.00 0.00 O ATOM 126 O5' DC A 5 -2.328 -5.465 6.853 1.00 0.00 O ATOM 127 C5' DC A 5 -2.164 -4.707 5.687 1.00 0.00 C ATOM 128 C4' DC A 5 -2.051 -5.555 4.445 1.00 0.00 C ATOM 129 O4' DC A 5 -1.518 -4.683 3.433 1.00 0.00 O ATOM 130 C3' DC A 5 -1.021 -6.644 4.590 1.00 0.00 C ATOM 131 O3' DC A 5 -1.368 -7.883 3.932 1.00 0.00 O ATOM 132 C2' DC A 5 0.280 -6.102 4.028 1.00 0.00 C ATOM 133 C1' DC A 5 -0.418 -5.413 2.838 1.00 0.00 C ATOM 134 N1 DC A 5 0.700 -4.712 2.107 1.00 0.00 N ATOM 135 C2 DC A 5 1.083 -3.455 2.646 1.00 0.00 C ATOM 136 O2 DC A 5 0.752 -3.162 3.773 1.00 0.00 O ATOM 137 N3 DC A 5 1.959 -2.618 1.911 1.00 0.00 N ATOM 138 C4 DC A 5 2.348 -3.055 0.681 1.00 0.00 C ATOM 139 N4 DC A 5 3.246 -2.371 0.093 1.00 0.00 N ATOM 140 C5 DC A 5 1.931 -4.296 0.150 1.00 0.00 C ATOM 141 C6 DC A 5 1.097 -5.126 0.897 1.00 0.00 C ATOM 142 H5' DC A 5 -1.348 -3.994 5.801 1.00 0.00 H ATOM 143 H5'' DC A 5 -3.067 -4.127 5.501 1.00 0.00 H ATOM 144 H4' DC A 5 -3.014 -5.976 4.158 1.00 0.00 H ATOM 145 H3' DC A 5 -0.804 -6.956 5.612 1.00 0.00 H ATOM 146 H2' DC A 5 0.673 -5.357 4.721 1.00 0.00 H ATOM 147 H2'' DC A 5 0.926 -6.922 3.718 1.00 0.00 H ATOM 148 H1' DC A 5 -0.721 -6.226 2.178 1.00 0.00 H ATOM 149 H41 DC A 5 3.590 -2.751 -0.777 1.00 0.00 H ATOM 150 H42 DC A 5 3.809 -1.634 0.492 1.00 0.00 H ATOM 151 H5 DC A 5 2.359 -4.725 -0.744 1.00 0.00 H ATOM 152 H6 DC A 5 0.866 -6.124 0.552 1.00 0.00 H ATOM 153 P DG A 6 -2.168 -9.124 4.572 1.00 0.00 P ATOM 154 OP1 DG A 6 -2.139 -8.997 6.024 1.00 0.00 O ATOM 155 OP2 DG A 6 -1.627 -10.342 3.997 1.00 0.00 O ATOM 156 O5' DG A 6 -3.670 -9.052 4.213 1.00 0.00 O ATOM 157 C5' DG A 6 -4.103 -9.066 2.855 1.00 0.00 C ATOM 158 C4' DG A 6 -4.214 -7.664 2.197 1.00 0.00 C ATOM 159 O4' DG A 6 -2.977 -7.216 1.563 1.00 0.00 O ATOM 160 C3' DG A 6 -5.088 -7.649 0.949 1.00 0.00 C ATOM 161 O3' DG A 6 -6.395 -7.752 1.383 1.00 0.00 O ATOM 162 C2' DG A 6 -4.738 -6.296 0.398 1.00 0.00 C ATOM 163 C1' DG A 6 -3.338 -6.108 0.853 1.00 0.00 C ATOM 164 N9 DG A 6 -2.349 -5.611 -0.155 1.00 0.00 N ATOM 165 C8 DG A 6 -1.719 -6.439 -1.104 1.00 0.00 C ATOM 166 N7 DG A 6 -0.892 -5.781 -1.843 1.00 0.00 N ATOM 167 C5 DG A 6 -1.042 -4.419 -1.494 1.00 0.00 C ATOM 168 C6 DG A 6 -0.479 -3.215 -2.039 1.00 0.00 C ATOM 169 O6 DG A 6 0.461 -3.131 -2.827 1.00 0.00 O ATOM 170 N1 DG A 6 -1.185 -2.109 -1.634 1.00 0.00 N ATOM 171 C2 DG A 6 -2.181 -2.090 -0.685 1.00 0.00 C ATOM 172 N2 DG A 6 -2.696 -0.866 -0.560 1.00 0.00 N ATOM 173 N3 DG A 6 -2.593 -3.209 -0.059 1.00 0.00 N ATOM 174 C4 DG A 6 -2.061 -4.317 -0.521 1.00 0.00 C ATOM 175 H5' DG A 6 -5.148 -9.333 3.009 1.00 0.00 H ATOM 176 H5'' DG A 6 -3.546 -9.783 2.252 1.00 0.00 H ATOM 177 H4' DG A 6 -4.582 -6.889 2.869 1.00 0.00 H ATOM 178 H3' DG A 6 -4.706 -8.409 0.267 1.00 0.00 H ATOM 179 H2' DG A 6 -4.755 -6.208 -0.687 1.00 0.00 H ATOM 180 H2'' DG A 6 -5.338 -5.525 0.881 1.00 0.00 H ATOM 181 H1' DG A 6 -3.288 -5.393 1.675 1.00 0.00 H ATOM 182 H8 DG A 6 -1.825 -7.513 -1.084 1.00 0.00 H ATOM 183 H1 DG A 6 -0.954 -1.213 -2.039 1.00 0.00 H ATOM 184 H22 DG A 6 -2.337 -0.125 -1.145 1.00 0.00 H ATOM 185 P DC A 7 -7.609 -8.160 0.468 1.00 0.00 P ATOM 186 OP1 DC A 7 -8.711 -8.316 1.411 1.00 0.00 O ATOM 187 OP2 DC A 7 -7.208 -9.354 -0.358 1.00 0.00 O ATOM 188 O5' DC A 7 -7.840 -6.968 -0.506 1.00 0.00 O ATOM 189 C5' DC A 7 -8.226 -5.715 -0.092 1.00 0.00 C ATOM 190 C4' DC A 7 -8.333 -4.711 -1.254 1.00 0.00 C ATOM 191 O4' DC A 7 -7.091 -4.246 -1.729 1.00 0.00 O ATOM 192 C3' DC A 7 -9.091 -5.262 -2.542 1.00 0.00 C ATOM 193 O3' DC A 7 -10.324 -4.630 -2.846 1.00 0.00 O ATOM 194 C2' DC A 7 -8.054 -4.986 -3.657 1.00 0.00 C ATOM 195 C1' DC A 7 -7.094 -3.895 -3.090 1.00 0.00 C ATOM 196 N1 DC A 7 -5.742 -3.903 -3.583 1.00 0.00 N ATOM 197 C2 DC A 7 -5.301 -2.964 -4.522 1.00 0.00 C ATOM 198 O2 DC A 7 -6.118 -2.157 -4.981 1.00 0.00 O ATOM 199 N3 DC A 7 -3.994 -2.917 -4.918 1.00 0.00 N ATOM 200 C4 DC A 7 -3.252 -3.943 -4.535 1.00 0.00 C ATOM 201 N4 DC A 7 -2.024 -3.890 -4.970 1.00 0.00 N ATOM 202 C5 DC A 7 -3.766 -5.066 -3.805 1.00 0.00 C ATOM 203 C6 DC A 7 -5.010 -5.051 -3.370 1.00 0.00 C ATOM 204 H5' DC A 7 -7.556 -5.345 0.684 1.00 0.00 H ATOM 205 H5'' DC A 7 -9.166 -5.788 0.454 1.00 0.00 H ATOM 206 H4' DC A 7 -8.931 -3.873 -0.897 1.00 0.00 H ATOM 207 H3' DC A 7 -9.323 -6.322 -2.431 1.00 0.00 H ATOM 208 H2' DC A 7 -7.573 -5.943 -3.855 1.00 0.00 H ATOM 209 H2'' DC A 7 -8.518 -4.594 -4.562 1.00 0.00 H ATOM 210 H1' DC A 7 -7.589 -2.930 -3.199 1.00 0.00 H ATOM 211 H41 DC A 7 -1.382 -4.618 -4.692 1.00 0.00 H ATOM 212 H42 DC A 7 -1.743 -2.977 -5.301 1.00 0.00 H ATOM 213 H5 DC A 7 -3.197 -5.936 -3.510 1.00 0.00 H ATOM 214 H6 DC A 7 -5.414 -5.872 -2.798 1.00 0.00 H ATOM 215 P DT A 8 -11.199 -5.113 -4.146 1.00 0.00 P ATOM 216 OP1 DT A 8 -12.584 -4.778 -3.728 1.00 0.00 O ATOM 217 OP2 DT A 8 -10.916 -6.546 -4.506 1.00 0.00 O ATOM 218 O5' DT A 8 -10.688 -4.123 -5.383 1.00 0.00 O ATOM 219 C5' DT A 8 -10.813 -2.714 -5.251 1.00 0.00 C ATOM 220 C4' DT A 8 -10.236 -2.061 -6.543 1.00 0.00 C ATOM 221 O4' DT A 8 -8.894 -2.496 -6.537 1.00 0.00 O ATOM 222 C3' DT A 8 -10.807 -2.536 -7.896 1.00 0.00 C ATOM 223 O3' DT A 8 -11.644 -1.550 -8.488 1.00 0.00 O ATOM 224 C2' DT A 8 -9.570 -2.700 -8.641 1.00 0.00 C ATOM 225 C1' DT A 8 -8.464 -2.198 -7.818 1.00 0.00 C ATOM 226 N1 DT A 8 -7.133 -2.732 -8.026 1.00 0.00 N ATOM 227 C2 DT A 8 -6.157 -1.942 -8.501 1.00 0.00 C ATOM 228 O2 DT A 8 -6.275 -0.750 -8.777 1.00 0.00 O ATOM 229 N3 DT A 8 -4.906 -2.421 -8.632 1.00 0.00 N ATOM 230 C4 DT A 8 -4.508 -3.728 -8.284 1.00 0.00 C ATOM 231 O4 DT A 8 -3.279 -3.974 -8.241 1.00 0.00 O ATOM 232 C5 DT A 8 -5.582 -4.517 -7.805 1.00 0.00 C ATOM 233 C7 DT A 8 -5.278 -5.901 -7.238 1.00 0.00 C ATOM 234 C6 DT A 8 -6.838 -4.115 -7.699 1.00 0.00 C ATOM 235 H5' DT A 8 -10.177 -2.488 -4.395 1.00 0.00 H ATOM 236 H5'' DT A 8 -11.855 -2.511 -5.004 1.00 0.00 H ATOM 237 H4' DT A 8 -10.318 -0.975 -6.535 1.00 0.00 H ATOM 238 H3' DT A 8 -11.261 -3.527 -7.917 1.00 0.00 H ATOM 239 H2' DT A 8 -9.421 -3.764 -8.822 1.00 0.00 H ATOM 240 H2'' DT A 8 -9.601 -2.107 -9.555 1.00 0.00 H ATOM 241 H1' DT A 8 -8.329 -1.134 -8.014 1.00 0.00 H ATOM 242 H3 DT A 8 -4.187 -1.755 -8.877 1.00 0.00 H ATOM 243 H71 DT A 8 -4.953 -6.586 -8.022 1.00 0.00 H ATOM 244 H72 DT A 8 -4.569 -5.864 -6.410 1.00 0.00 H ATOM 245 H73 DT A 8 -6.240 -6.342 -6.977 1.00 0.00 H ATOM 246 H6 DT A 8 -7.633 -4.654 -7.206 1.00 0.00 H ATOM 247 P DA A 9 -12.508 -1.927 -9.835 1.00 0.00 P ATOM 248 OP1 DA A 9 -13.691 -1.024 -9.767 1.00 0.00 O ATOM 249 OP2 DA A 9 -12.763 -3.335 -9.895 1.00 0.00 O ATOM 250 O5' DA A 9 -11.482 -1.419 -10.944 1.00 0.00 O ATOM 251 C5' DA A 9 -11.230 -0.020 -11.199 1.00 0.00 C ATOM 252 C4' DA A 9 -10.033 0.166 -12.191 1.00 0.00 C ATOM 253 O4' DA A 9 -8.807 -0.310 -11.657 1.00 0.00 O ATOM 254 C3' DA A 9 -10.172 -0.586 -13.517 1.00 0.00 C ATOM 255 O3' DA A 9 -9.854 0.352 -14.543 1.00 0.00 O ATOM 256 C2' DA A 9 -9.046 -1.539 -13.649 1.00 0.00 C ATOM 257 C1' DA A 9 -8.034 -0.869 -12.743 1.00 0.00 C ATOM 258 N9 DA A 9 -6.950 -1.760 -12.310 1.00 0.00 N ATOM 259 C8 DA A 9 -7.010 -3.015 -11.815 1.00 0.00 C ATOM 260 N7 DA A 9 -5.857 -3.545 -11.479 1.00 0.00 N ATOM 261 C5 DA A 9 -4.976 -2.542 -11.871 1.00 0.00 C ATOM 262 C6 DA A 9 -3.569 -2.445 -11.898 1.00 0.00 C ATOM 263 N6 DA A 9 -2.603 -3.360 -11.923 1.00 0.00 N ATOM 264 N1 DA A 9 -2.988 -1.310 -12.316 1.00 0.00 N ATOM 265 C2 DA A 9 -3.741 -0.235 -12.486 1.00 0.00 C ATOM 266 N3 DA A 9 -5.100 -0.145 -12.451 1.00 0.00 N ATOM 267 C4 DA A 9 -5.619 -1.382 -12.220 1.00 0.00 C ATOM 268 H5' DA A 9 -10.863 0.418 -10.271 1.00 0.00 H ATOM 269 H5'' DA A 9 -12.167 0.431 -11.526 1.00 0.00 H ATOM 270 H4' DA A 9 -9.943 1.249 -12.270 1.00 0.00 H ATOM 271 H3' DA A 9 -11.160 -1.021 -13.666 1.00 0.00 H ATOM 272 H2' DA A 9 -9.347 -2.466 -13.161 1.00 0.00 H ATOM 273 H2'' DA A 9 -8.734 -1.725 -14.677 1.00 0.00 H ATOM 274 H1' DA A 9 -7.562 -0.132 -13.393 1.00 0.00 H ATOM 275 H8 DA A 9 -7.945 -3.526 -11.631 1.00 0.00 H ATOM 276 H61 DA A 9 -1.735 -2.863 -12.064 1.00 0.00 H ATOM 277 H62 DA A 9 -2.758 -4.353 -11.816 1.00 0.00 H ATOM 278 H2 DA A 9 -3.231 0.641 -12.859 1.00 0.00 H ATOM 279 P DC A 10 -10.965 1.305 -15.170 1.00 0.00 P ATOM 280 OP1 DC A 10 -11.818 1.804 -14.121 1.00 0.00 O ATOM 281 OP2 DC A 10 -11.594 0.520 -16.242 1.00 0.00 O ATOM 282 O5' DC A 10 -10.096 2.470 -15.832 1.00 0.00 O ATOM 283 C5' DC A 10 -9.491 3.440 -15.043 1.00 0.00 C ATOM 284 C4' DC A 10 -8.031 3.752 -15.390 1.00 0.00 C ATOM 285 O4' DC A 10 -7.218 2.731 -14.886 1.00 0.00 O ATOM 286 C3' DC A 10 -7.818 3.820 -16.943 1.00 0.00 C ATOM 287 O3' DC A 10 -6.951 4.966 -17.180 1.00 0.00 O ATOM 288 C2' DC A 10 -7.169 2.552 -17.230 1.00 0.00 C ATOM 289 C1' DC A 10 -6.371 2.256 -15.938 1.00 0.00 C ATOM 290 N1 DC A 10 -5.859 0.889 -15.864 1.00 0.00 N ATOM 291 C2 DC A 10 -4.496 0.642 -15.761 1.00 0.00 C ATOM 292 O2 DC A 10 -3.621 1.529 -15.855 1.00 0.00 O ATOM 293 N3 DC A 10 -4.081 -0.693 -15.687 1.00 0.00 N ATOM 294 C4 DC A 10 -5.039 -1.594 -15.466 1.00 0.00 C ATOM 295 N4 DC A 10 -4.511 -2.749 -15.361 1.00 0.00 N ATOM 296 C5 DC A 10 -6.365 -1.434 -15.803 1.00 0.00 C ATOM 297 C6 DC A 10 -6.754 -0.153 -15.938 1.00 0.00 C ATOM 298 H5' DC A 10 -9.526 3.091 -14.011 1.00 0.00 H ATOM 299 H5'' DC A 10 -10.125 4.324 -14.985 1.00 0.00 H ATOM 300 H4' DC A 10 -7.796 4.725 -14.957 1.00 0.00 H ATOM 301 H3' DC A 10 -8.735 3.888 -17.528 1.00 0.00 H ATOM 302 H2' DC A 10 -7.977 1.834 -17.372 1.00 0.00 H ATOM 303 H2'' DC A 10 -6.574 2.609 -18.142 1.00 0.00 H ATOM 304 H1' DC A 10 -5.524 2.940 -15.990 1.00 0.00 H ATOM 305 H41 DC A 10 -5.093 -3.464 -15.773 1.00 0.00 H ATOM 306 H42 DC A 10 -3.521 -2.783 -15.169 1.00 0.00 H ATOM 307 H5 DC A 10 -6.985 -2.314 -15.880 1.00 0.00 H ATOM 308 H6 DC A 10 -7.814 0.049 -16.003 1.00 0.00 H ATOM 309 P DC A 11 -6.562 5.554 -18.637 1.00 0.00 P ATOM 310 OP1 DC A 11 -5.839 6.801 -18.475 1.00 0.00 O ATOM 311 OP2 DC A 11 -7.819 5.564 -19.428 1.00 0.00 O ATOM 312 O5' DC A 11 -5.554 4.554 -19.306 1.00 0.00 O ATOM 313 C5' DC A 11 -4.277 4.415 -18.707 1.00 0.00 C ATOM 314 C4' DC A 11 -3.514 3.189 -19.223 1.00 0.00 C ATOM 315 O4' DC A 11 -4.191 2.028 -18.788 1.00 0.00 O ATOM 316 C3' DC A 11 -3.560 3.021 -20.732 1.00 0.00 C ATOM 317 O3' DC A 11 -2.280 3.207 -21.354 1.00 0.00 O ATOM 318 C2' DC A 11 -4.114 1.640 -20.952 1.00 0.00 C ATOM 319 C1' DC A 11 -3.955 0.962 -19.634 1.00 0.00 C ATOM 320 N1 DC A 11 -4.873 -0.244 -19.512 1.00 0.00 N ATOM 321 C2 DC A 11 -4.307 -1.488 -19.280 1.00 0.00 C ATOM 322 O2 DC A 11 -3.080 -1.742 -19.383 1.00 0.00 O ATOM 323 N3 DC A 11 -5.192 -2.533 -18.999 1.00 0.00 N ATOM 324 C4 DC A 11 -6.508 -2.352 -19.119 1.00 0.00 C ATOM 325 N4 DC A 11 -7.303 -3.329 -18.778 1.00 0.00 N ATOM 326 C5 DC A 11 -7.090 -1.084 -19.409 1.00 0.00 C ATOM 327 C6 DC A 11 -6.242 -0.050 -19.562 1.00 0.00 C ATOM 328 H5' DC A 11 -4.399 4.340 -17.626 1.00 0.00 H ATOM 329 H5'' DC A 11 -3.686 5.295 -18.963 1.00 0.00 H ATOM 330 H4' DC A 11 -2.504 3.199 -18.814 1.00 0.00 H ATOM 331 H3' DC A 11 -4.185 3.753 -21.241 1.00 0.00 H ATOM 332 HO3' DC A 11 -1.824 2.370 -21.241 1.00 0.00 H ATOM 333 H2' DC A 11 -5.184 1.685 -21.156 1.00 0.00 H ATOM 334 H2'' DC A 11 -3.654 1.074 -21.760 1.00 0.00 H ATOM 335 H1' DC A 11 -2.931 0.634 -19.456 1.00 0.00 H ATOM 336 H41 DC A 11 -8.288 -3.148 -18.651 1.00 0.00 H ATOM 337 H42 DC A 11 -6.821 -4.184 -18.536 1.00 0.00 H ATOM 338 H5 DC A 11 -8.146 -0.861 -19.431 1.00 0.00 H ATOM 339 H6 DC A 11 -6.709 0.909 -19.731 1.00 0.00 H TER 340 DC A 11 ATOM 341 O5' DG B 12 2.595 -10.618 -16.992 1.00 0.00 O ATOM 342 C5' DG B 12 3.308 -9.691 -16.240 1.00 0.00 C ATOM 343 C4' DG B 12 4.005 -8.683 -17.150 1.00 0.00 C ATOM 344 O4' DG B 12 3.163 -8.293 -18.197 1.00 0.00 O ATOM 345 C3' DG B 12 4.480 -7.402 -16.577 1.00 0.00 C ATOM 346 O3' DG B 12 5.636 -6.937 -17.338 1.00 0.00 O ATOM 347 C2' DG B 12 3.302 -6.518 -16.763 1.00 0.00 C ATOM 348 C1' DG B 12 2.539 -7.050 -17.951 1.00 0.00 C ATOM 349 N9 DG B 12 1.035 -7.030 -17.703 1.00 0.00 N ATOM 350 C8 DG B 12 0.304 -7.923 -16.989 1.00 0.00 C ATOM 351 N7 DG B 12 -0.850 -7.408 -16.679 1.00 0.00 N ATOM 352 C5 DG B 12 -0.950 -6.199 -17.373 1.00 0.00 C ATOM 353 C6 DG B 12 -2.068 -5.206 -17.468 1.00 0.00 C ATOM 354 O6 DG B 12 -3.184 -5.214 -16.956 1.00 0.00 O ATOM 355 N1 DG B 12 -1.745 -4.128 -18.329 1.00 0.00 N ATOM 356 C2 DG B 12 -0.534 -3.900 -18.782 1.00 0.00 C ATOM 357 N2 DG B 12 -0.488 -2.796 -19.408 1.00 0.00 N ATOM 358 N3 DG B 12 0.538 -4.772 -18.665 1.00 0.00 N ATOM 359 C4 DG B 12 0.236 -5.952 -18.045 1.00 0.00 C ATOM 360 H5' DG B 12 4.017 -10.236 -15.614 1.00 0.00 H ATOM 361 H5'' DG B 12 2.644 -9.145 -15.570 1.00 0.00 H ATOM 362 H4' DG B 12 4.910 -9.141 -17.552 1.00 0.00 H ATOM 363 H3' DG B 12 4.801 -7.434 -15.536 1.00 0.00 H ATOM 364 H2' DG B 12 2.758 -6.366 -15.831 1.00 0.00 H ATOM 365 H2'' DG B 12 3.624 -5.525 -17.076 1.00 0.00 H ATOM 366 H1' DG B 12 2.681 -6.283 -18.710 1.00 0.00 H ATOM 367 H8 DG B 12 0.707 -8.840 -16.586 1.00 0.00 H ATOM 368 H1 DG B 12 -2.477 -3.450 -18.482 1.00 0.00 H ATOM 369 H21 DG B 12 0.414 -2.437 -19.689 1.00 0.00 H ATOM 370 H22 DG B 12 -1.352 -2.276 -19.456 1.00 0.00 H ATOM 371 HO5' DG B 12 2.602 -11.461 -16.531 1.00 0.00 H ATOM 372 P DG B 13 6.675 -5.879 -16.797 1.00 0.00 P ATOM 373 OP1 DG B 13 7.874 -5.955 -17.617 1.00 0.00 O ATOM 374 OP2 DG B 13 6.826 -5.992 -15.317 1.00 0.00 O ATOM 375 O5' DG B 13 5.869 -4.502 -17.175 1.00 0.00 O ATOM 376 C5' DG B 13 6.008 -3.796 -18.389 1.00 0.00 C ATOM 377 C4' DG B 13 5.487 -2.328 -18.356 1.00 0.00 C ATOM 378 O4' DG B 13 4.081 -2.401 -18.246 1.00 0.00 O ATOM 379 C3' DG B 13 5.983 -1.433 -17.156 1.00 0.00 C ATOM 380 O3' DG B 13 6.130 -0.088 -17.698 1.00 0.00 O ATOM 381 C2' DG B 13 4.850 -1.519 -16.164 1.00 0.00 C ATOM 382 C1' DG B 13 3.672 -1.631 -17.152 1.00 0.00 C ATOM 383 N9 DG B 13 2.457 -2.250 -16.526 1.00 0.00 N ATOM 384 C8 DG B 13 2.418 -3.448 -15.842 1.00 0.00 C ATOM 385 N7 DG B 13 1.279 -3.828 -15.458 1.00 0.00 N ATOM 386 C5 DG B 13 0.468 -2.721 -15.753 1.00 0.00 C ATOM 387 C6 DG B 13 -0.899 -2.403 -15.501 1.00 0.00 C ATOM 388 O6 DG B 13 -1.711 -3.134 -14.892 1.00 0.00 O ATOM 389 N1 DG B 13 -1.264 -1.200 -15.937 1.00 0.00 N ATOM 390 C2 DG B 13 -0.549 -0.327 -16.676 1.00 0.00 C ATOM 391 N2 DG B 13 -1.041 0.863 -16.747 1.00 0.00 N ATOM 392 N3 DG B 13 0.768 -0.516 -16.918 1.00 0.00 N ATOM 393 C4 DG B 13 1.188 -1.720 -16.442 1.00 0.00 C ATOM 394 H5' DG B 13 5.489 -4.301 -19.204 1.00 0.00 H ATOM 395 H5'' DG B 13 7.047 -3.831 -18.716 1.00 0.00 H ATOM 396 H4' DG B 13 5.725 -1.995 -19.366 1.00 0.00 H ATOM 397 H3' DG B 13 6.894 -1.897 -16.773 1.00 0.00 H ATOM 398 H2' DG B 13 5.180 -2.373 -15.574 1.00 0.00 H ATOM 399 H2'' DG B 13 4.836 -0.692 -15.454 1.00 0.00 H ATOM 400 H1' DG B 13 3.443 -0.623 -17.497 1.00 0.00 H ATOM 401 H8 DG B 13 3.330 -3.963 -15.575 1.00 0.00 H ATOM 402 H1 DG B 13 -2.198 -0.851 -15.770 1.00 0.00 H ATOM 403 H21 DG B 13 -0.422 1.521 -17.198 1.00 0.00 H ATOM 404 H22 DG B 13 -1.997 1.078 -16.499 1.00 0.00 H ATOM 405 P DT B 14 6.888 1.148 -17.022 1.00 0.00 P ATOM 406 OP1 DT B 14 7.225 2.209 -17.992 1.00 0.00 O ATOM 407 OP2 DT B 14 7.932 0.623 -16.165 1.00 0.00 O ATOM 408 O5' DT B 14 5.643 1.623 -16.177 1.00 0.00 O ATOM 409 C5' DT B 14 4.464 2.143 -16.796 1.00 0.00 C ATOM 410 C4' DT B 14 3.415 2.617 -15.762 1.00 0.00 C ATOM 411 O4' DT B 14 2.606 1.531 -15.326 1.00 0.00 O ATOM 412 C3' DT B 14 3.986 3.279 -14.563 1.00 0.00 C ATOM 413 O3' DT B 14 3.760 4.726 -14.520 1.00 0.00 O ATOM 414 C2' DT B 14 3.293 2.503 -13.411 1.00 0.00 C ATOM 415 C1' DT B 14 2.067 1.819 -14.062 1.00 0.00 C ATOM 416 N1 DT B 14 1.664 0.567 -13.305 1.00 0.00 N ATOM 417 C2 DT B 14 0.294 0.447 -13.040 1.00 0.00 C ATOM 418 O2 DT B 14 -0.567 1.229 -13.332 1.00 0.00 O ATOM 419 N3 DT B 14 -0.127 -0.791 -12.677 1.00 0.00 N ATOM 420 C4 DT B 14 0.689 -1.782 -12.241 1.00 0.00 C ATOM 421 O4 DT B 14 0.084 -2.796 -11.768 1.00 0.00 O ATOM 422 C5 DT B 14 2.134 -1.543 -12.426 1.00 0.00 C ATOM 423 C7 DT B 14 3.143 -2.557 -11.971 1.00 0.00 C ATOM 424 C6 DT B 14 2.605 -0.406 -12.973 1.00 0.00 C ATOM 425 H5' DT B 14 4.119 1.369 -17.482 1.00 0.00 H ATOM 426 H5'' DT B 14 4.748 2.958 -17.464 1.00 0.00 H ATOM 427 H4' DT B 14 2.743 3.325 -16.247 1.00 0.00 H ATOM 428 H3' DT B 14 5.054 3.070 -14.524 1.00 0.00 H ATOM 429 H2' DT B 14 3.991 1.725 -13.102 1.00 0.00 H ATOM 430 H2'' DT B 14 3.055 3.181 -12.590 1.00 0.00 H ATOM 431 H1' DT B 14 1.310 2.604 -14.020 1.00 0.00 H ATOM 432 H3 DT B 14 -1.135 -0.845 -12.654 1.00 0.00 H ATOM 433 H71 DT B 14 2.959 -3.510 -12.467 1.00 0.00 H ATOM 434 H72 DT B 14 4.129 -2.180 -12.242 1.00 0.00 H ATOM 435 H73 DT B 14 3.068 -2.743 -10.899 1.00 0.00 H ATOM 436 H6 DT B 14 3.650 -0.269 -13.209 1.00 0.00 H ATOM 437 P DA B 15 4.050 5.750 -13.368 1.00 0.00 P ATOM 438 OP1 DA B 15 3.832 7.038 -14.057 1.00 0.00 O ATOM 439 OP2 DA B 15 5.350 5.395 -12.785 1.00 0.00 O ATOM 440 O5' DA B 15 2.970 5.505 -12.305 1.00 0.00 O ATOM 441 C5' DA B 15 1.627 6.034 -12.550 1.00 0.00 C ATOM 442 C4' DA B 15 0.505 5.431 -11.614 1.00 0.00 C ATOM 443 O4' DA B 15 0.562 4.009 -11.560 1.00 0.00 O ATOM 444 C3' DA B 15 0.417 5.961 -10.192 1.00 0.00 C ATOM 445 O3' DA B 15 -0.469 7.037 -10.186 1.00 0.00 O ATOM 446 C2' DA B 15 -0.185 4.692 -9.456 1.00 0.00 C ATOM 447 C1' DA B 15 -0.364 3.659 -10.575 1.00 0.00 C ATOM 448 N9 DA B 15 -0.170 2.220 -10.108 1.00 0.00 N ATOM 449 C8 DA B 15 0.971 1.489 -9.965 1.00 0.00 C ATOM 450 N7 DA B 15 0.759 0.330 -9.615 1.00 0.00 N ATOM 451 C5 DA B 15 -0.599 0.244 -9.400 1.00 0.00 C ATOM 452 C6 DA B 15 -1.468 -0.729 -8.963 1.00 0.00 C ATOM 453 N6 DA B 15 -1.266 -1.987 -8.748 1.00 0.00 N ATOM 454 N1 DA B 15 -2.778 -0.439 -8.792 1.00 0.00 N ATOM 455 C2 DA B 15 -3.240 0.793 -9.106 1.00 0.00 C ATOM 456 N3 DA B 15 -2.512 1.788 -9.598 1.00 0.00 N ATOM 457 C4 DA B 15 -1.220 1.437 -9.686 1.00 0.00 C ATOM 458 H5' DA B 15 1.407 5.749 -13.579 1.00 0.00 H ATOM 459 H5'' DA B 15 1.628 7.119 -12.448 1.00 0.00 H ATOM 460 H4' DA B 15 -0.490 5.698 -11.969 1.00 0.00 H ATOM 461 H3' DA B 15 1.409 6.165 -9.790 1.00 0.00 H ATOM 462 H2' DA B 15 0.552 4.366 -8.722 1.00 0.00 H ATOM 463 H2'' DA B 15 -1.165 4.892 -9.022 1.00 0.00 H ATOM 464 H1' DA B 15 -1.396 3.651 -10.928 1.00 0.00 H ATOM 465 H8 DA B 15 1.958 1.848 -10.214 1.00 0.00 H ATOM 466 H61 DA B 15 -2.038 -2.546 -8.415 1.00 0.00 H ATOM 467 H62 DA B 15 -0.372 -2.339 -9.060 1.00 0.00 H ATOM 468 H2 DA B 15 -4.295 0.971 -8.963 1.00 0.00 H ATOM 469 P DG B 16 -0.459 8.233 -9.157 1.00 0.00 P ATOM 470 OP1 DG B 16 -1.234 9.288 -9.804 1.00 0.00 O ATOM 471 OP2 DG B 16 0.977 8.553 -8.842 1.00 0.00 O ATOM 472 O5' DG B 16 -1.232 7.714 -7.825 1.00 0.00 O ATOM 473 C5' DG B 16 -2.729 7.575 -7.820 1.00 0.00 C ATOM 474 C4' DG B 16 -3.270 6.575 -6.819 1.00 0.00 C ATOM 475 O4' DG B 16 -2.962 5.195 -7.236 1.00 0.00 O ATOM 476 C3' DG B 16 -2.663 6.807 -5.499 1.00 0.00 C ATOM 477 O3' DG B 16 -3.626 6.611 -4.415 1.00 0.00 O ATOM 478 C2' DG B 16 -1.692 5.677 -5.345 1.00 0.00 C ATOM 479 C1' DG B 16 -2.437 4.597 -6.082 1.00 0.00 C ATOM 480 N9 DG B 16 -1.753 3.306 -6.360 1.00 0.00 N ATOM 481 C8 DG B 16 -0.470 2.960 -6.160 1.00 0.00 C ATOM 482 N7 DG B 16 -0.245 1.686 -6.095 1.00 0.00 N ATOM 483 C5 DG B 16 -1.510 1.110 -6.073 1.00 0.00 C ATOM 484 C6 DG B 16 -1.924 -0.233 -5.838 1.00 0.00 C ATOM 485 O6 DG B 16 -1.159 -1.240 -5.621 1.00 0.00 O ATOM 486 N1 DG B 16 -3.309 -0.355 -5.709 1.00 0.00 N ATOM 487 C2 DG B 16 -4.153 0.711 -5.866 1.00 0.00 C ATOM 488 N2 DG B 16 -5.416 0.416 -5.837 1.00 0.00 N ATOM 489 N3 DG B 16 -3.835 1.933 -6.214 1.00 0.00 N ATOM 490 C4 DG B 16 -2.441 2.100 -6.274 1.00 0.00 C ATOM 491 H5' DG B 16 -3.071 7.324 -8.824 1.00 0.00 H ATOM 492 H5'' DG B 16 -3.106 8.550 -7.516 1.00 0.00 H ATOM 493 H4' DG B 16 -4.354 6.671 -6.752 1.00 0.00 H ATOM 494 H3' DG B 16 -2.133 7.748 -5.351 1.00 0.00 H ATOM 495 H2' DG B 16 -0.854 5.915 -6.001 1.00 0.00 H ATOM 496 H2'' DG B 16 -1.370 5.320 -4.368 1.00 0.00 H ATOM 497 H1' DG B 16 -3.257 4.393 -5.393 1.00 0.00 H ATOM 498 H8 DG B 16 0.366 3.644 -6.163 1.00 0.00 H ATOM 499 H1 DG B 16 -3.685 -1.275 -5.526 1.00 0.00 H ATOM 500 H21 DG B 16 -5.995 1.229 -5.991 1.00 0.00 H ATOM 501 H22 DG B 16 -5.759 -0.498 -5.579 1.00 0.00 H ATOM 502 P DC B 17 -4.752 7.632 -4.026 1.00 0.00 P ATOM 503 OP1 DC B 17 -6.077 7.153 -4.387 1.00 0.00 O ATOM 504 OP2 DC B 17 -4.438 9.032 -4.424 1.00 0.00 O ATOM 505 O5' DC B 17 -4.674 7.493 -2.409 1.00 0.00 O ATOM 506 C5' DC B 17 -3.604 7.893 -1.643 1.00 0.00 C ATOM 507 C4' DC B 17 -4.049 7.474 -0.301 1.00 0.00 C ATOM 508 O4' DC B 17 -3.864 6.078 -0.111 1.00 0.00 O ATOM 509 C3' DC B 17 -3.277 8.215 0.793 1.00 0.00 C ATOM 510 O3' DC B 17 -4.247 8.560 1.776 1.00 0.00 O ATOM 511 C2' DC B 17 -2.306 7.161 1.223 1.00 0.00 C ATOM 512 C1' DC B 17 -3.190 5.928 1.137 1.00 0.00 C ATOM 513 N1 DC B 17 -2.403 4.692 1.382 1.00 0.00 N ATOM 514 C2 DC B 17 -1.731 4.009 0.316 1.00 0.00 C ATOM 515 O2 DC B 17 -2.038 4.195 -0.852 1.00 0.00 O ATOM 516 N3 DC B 17 -0.774 3.138 0.601 1.00 0.00 N ATOM 517 C4 DC B 17 -0.400 2.885 1.808 1.00 0.00 C ATOM 518 N4 DC B 17 0.636 2.164 2.073 1.00 0.00 N ATOM 519 C5 DC B 17 -1.036 3.559 2.908 1.00 0.00 C ATOM 520 C6 DC B 17 -1.976 4.508 2.650 1.00 0.00 C ATOM 521 H5' DC B 17 -3.475 8.974 -1.673 1.00 0.00 H ATOM 522 H5'' DC B 17 -2.612 7.535 -1.912 1.00 0.00 H ATOM 523 H4' DC B 17 -5.097 7.774 -0.317 1.00 0.00 H ATOM 524 H3' DC B 17 -2.769 9.125 0.475 1.00 0.00 H ATOM 525 H2' DC B 17 -1.407 7.147 0.607 1.00 0.00 H ATOM 526 H2'' DC B 17 -1.917 7.426 2.207 1.00 0.00 H ATOM 527 H1' DC B 17 -3.949 6.052 1.909 1.00 0.00 H ATOM 528 H41 DC B 17 0.819 2.026 3.057 1.00 0.00 H ATOM 529 H42 DC B 17 1.055 1.541 1.397 1.00 0.00 H ATOM 530 H5 DC B 17 -0.668 3.365 3.905 1.00 0.00 H ATOM 531 H6 DC B 17 -2.366 5.025 3.514 1.00 0.00 H ATOM 532 P DG B 18 -3.924 9.452 3.090 1.00 0.00 P ATOM 533 OP1 DG B 18 -5.180 10.063 3.533 1.00 0.00 O ATOM 534 OP2 DG B 18 -2.791 10.388 2.847 1.00 0.00 O ATOM 535 O5' DG B 18 -3.454 8.412 4.228 1.00 0.00 O ATOM 536 C5' DG B 18 -4.379 7.637 4.968 1.00 0.00 C ATOM 537 C4' DG B 18 -3.675 6.912 6.122 1.00 0.00 C ATOM 538 O4' DG B 18 -2.809 5.906 5.756 1.00 0.00 O ATOM 539 C3' DG B 18 -2.750 7.780 6.948 1.00 0.00 C ATOM 540 O3' DG B 18 -3.403 8.465 8.003 1.00 0.00 O ATOM 541 C2' DG B 18 -1.716 6.848 7.550 1.00 0.00 C ATOM 542 C1' DG B 18 -1.516 5.843 6.433 1.00 0.00 C ATOM 543 N9 DG B 18 -0.369 6.078 5.539 1.00 0.00 N ATOM 544 C8 DG B 18 0.021 7.224 4.878 1.00 0.00 C ATOM 545 N7 DG B 18 1.077 7.067 4.073 1.00 0.00 N ATOM 546 C5 DG B 18 1.506 5.742 4.369 1.00 0.00 C ATOM 547 C6 DG B 18 2.617 4.922 3.976 1.00 0.00 C ATOM 548 O6 DG B 18 3.440 5.160 3.081 1.00 0.00 O ATOM 549 N1 DG B 18 2.725 3.658 4.614 1.00 0.00 N ATOM 550 C2 DG B 18 1.799 3.254 5.501 1.00 0.00 C ATOM 551 N2 DG B 18 1.795 1.916 5.686 1.00 0.00 N ATOM 552 N3 DG B 18 0.788 3.971 5.952 1.00 0.00 N ATOM 553 C4 DG B 18 0.716 5.202 5.344 1.00 0.00 C ATOM 554 H5' DG B 18 -4.996 7.002 4.334 1.00 0.00 H ATOM 555 H5'' DG B 18 -5.083 8.354 5.390 1.00 0.00 H ATOM 556 H4' DG B 18 -4.527 6.580 6.714 1.00 0.00 H ATOM 557 H3' DG B 18 -2.194 8.461 6.304 1.00 0.00 H ATOM 558 H2' DG B 18 -0.771 7.257 7.908 1.00 0.00 H ATOM 559 H2'' DG B 18 -2.253 6.242 8.280 1.00 0.00 H ATOM 560 H1' DG B 18 -1.370 4.890 6.943 1.00 0.00 H ATOM 561 H8 DG B 18 -0.561 8.133 4.913 1.00 0.00 H ATOM 562 H1 DG B 18 3.506 3.033 4.472 1.00 0.00 H ATOM 563 H21 DG B 18 0.998 1.538 6.178 1.00 0.00 H ATOM 564 H22 DG B 18 2.677 1.424 5.694 1.00 0.00 H ATOM 565 P DA B 19 -2.716 9.737 8.714 1.00 0.00 P ATOM 566 OP1 DA B 19 -3.744 10.456 9.475 1.00 0.00 O ATOM 567 OP2 DA B 19 -2.110 10.543 7.622 1.00 0.00 O ATOM 568 O5' DA B 19 -1.622 9.263 9.746 1.00 0.00 O ATOM 569 C5' DA B 19 -1.752 8.450 10.854 1.00 0.00 C ATOM 570 C4' DA B 19 -0.479 8.052 11.564 1.00 0.00 C ATOM 571 O4' DA B 19 0.197 6.973 10.881 1.00 0.00 O ATOM 572 C3' DA B 19 0.642 9.160 11.876 1.00 0.00 C ATOM 573 O3' DA B 19 1.209 9.226 13.223 1.00 0.00 O ATOM 574 C2' DA B 19 1.741 8.712 10.968 1.00 0.00 C ATOM 575 C1' DA B 19 1.574 7.195 10.912 1.00 0.00 C ATOM 576 N9 DA B 19 2.294 6.479 9.860 1.00 0.00 N ATOM 577 C8 DA B 19 3.105 6.954 8.844 1.00 0.00 C ATOM 578 N7 DA B 19 3.746 5.992 8.145 1.00 0.00 N ATOM 579 C5 DA B 19 3.430 4.850 8.913 1.00 0.00 C ATOM 580 C6 DA B 19 3.963 3.558 8.892 1.00 0.00 C ATOM 581 N6 DA B 19 4.947 3.039 8.187 1.00 0.00 N ATOM 582 N1 DA B 19 3.479 2.656 9.731 1.00 0.00 N ATOM 583 C2 DA B 19 2.495 3.034 10.543 1.00 0.00 C ATOM 584 N3 DA B 19 1.954 4.239 10.738 1.00 0.00 N ATOM 585 C4 DA B 19 2.489 5.125 9.870 1.00 0.00 C ATOM 586 H5' DA B 19 -2.163 7.558 10.379 1.00 0.00 H ATOM 587 H5'' DA B 19 -2.422 8.923 11.573 1.00 0.00 H ATOM 588 H4' DA B 19 -0.771 7.621 12.522 1.00 0.00 H ATOM 589 H3' DA B 19 0.364 10.165 11.559 1.00 0.00 H ATOM 590 H2' DA B 19 1.407 9.089 10.001 1.00 0.00 H ATOM 591 H2'' DA B 19 2.720 9.085 11.267 1.00 0.00 H ATOM 592 H1' DA B 19 1.935 6.836 11.876 1.00 0.00 H ATOM 593 H8 DA B 19 3.090 7.988 8.536 1.00 0.00 H ATOM 594 H61 DA B 19 5.170 2.069 8.356 1.00 0.00 H ATOM 595 H62 DA B 19 5.280 3.549 7.382 1.00 0.00 H ATOM 596 H2 DA B 19 2.004 2.359 11.230 1.00 0.00 H ATOM 597 P DT B 20 0.224 9.443 14.433 1.00 0.00 P ATOM 598 OP1 DT B 20 -1.013 10.087 14.002 1.00 0.00 O ATOM 599 OP2 DT B 20 1.055 10.061 15.511 1.00 0.00 O ATOM 600 O5' DT B 20 -0.240 8.102 15.136 1.00 0.00 O ATOM 601 C5' DT B 20 -1.569 7.572 15.090 1.00 0.00 C ATOM 602 C4' DT B 20 -1.539 6.143 15.619 1.00 0.00 C ATOM 603 O4' DT B 20 -0.653 5.409 14.826 1.00 0.00 O ATOM 604 C3' DT B 20 -1.043 6.150 17.064 1.00 0.00 C ATOM 605 O3' DT B 20 -1.897 5.288 17.886 1.00 0.00 O ATOM 606 C2' DT B 20 0.387 5.565 16.885 1.00 0.00 C ATOM 607 C1' DT B 20 0.287 4.709 15.634 1.00 0.00 C ATOM 608 N1 DT B 20 1.597 4.649 14.979 1.00 0.00 N ATOM 609 C2 DT B 20 2.128 3.384 14.730 1.00 0.00 C ATOM 610 O2 DT B 20 1.565 2.317 14.995 1.00 0.00 O ATOM 611 N3 DT B 20 3.322 3.343 14.040 1.00 0.00 N ATOM 612 C4 DT B 20 4.008 4.450 13.618 1.00 0.00 C ATOM 613 O4 DT B 20 5.054 4.223 13.012 1.00 0.00 O ATOM 614 C5 DT B 20 3.401 5.738 13.844 1.00 0.00 C ATOM 615 C7 DT B 20 4.062 7.067 13.356 1.00 0.00 C ATOM 616 C6 DT B 20 2.222 5.765 14.501 1.00 0.00 C ATOM 617 H5' DT B 20 -1.935 7.515 14.066 1.00 0.00 H ATOM 618 H5'' DT B 20 -2.272 8.195 15.644 1.00 0.00 H ATOM 619 H4' DT B 20 -2.547 5.734 15.555 1.00 0.00 H ATOM 620 H3' DT B 20 -0.919 7.171 17.423 1.00 0.00 H ATOM 621 H2' DT B 20 1.034 6.395 16.605 1.00 0.00 H ATOM 622 H2'' DT B 20 0.910 5.065 17.701 1.00 0.00 H ATOM 623 H1' DT B 20 -0.010 3.714 15.963 1.00 0.00 H ATOM 624 H3 DT B 20 3.707 2.436 13.819 1.00 0.00 H ATOM 625 H71 DT B 20 5.086 7.073 13.727 1.00 0.00 H ATOM 626 H72 DT B 20 3.947 7.036 12.273 1.00 0.00 H ATOM 627 H73 DT B 20 3.418 7.849 13.758 1.00 0.00 H ATOM 628 H6 DT B 20 1.782 6.736 14.673 1.00 0.00 H ATOM 629 P DG B 21 -1.611 4.897 19.395 1.00 0.00 P ATOM 630 OP1 DG B 21 -2.933 4.508 19.943 1.00 0.00 O ATOM 631 OP2 DG B 21 -0.963 6.064 20.048 1.00 0.00 O ATOM 632 O5' DG B 21 -0.682 3.594 19.417 1.00 0.00 O ATOM 633 C5' DG B 21 -1.085 2.364 18.828 1.00 0.00 C ATOM 634 C4' DG B 21 0.164 1.521 18.659 1.00 0.00 C ATOM 635 O4' DG B 21 1.104 2.059 17.672 1.00 0.00 O ATOM 636 C3' DG B 21 0.907 1.234 19.974 1.00 0.00 C ATOM 637 O3' DG B 21 0.695 -0.186 20.297 1.00 0.00 O ATOM 638 C2' DG B 21 2.341 1.630 19.521 1.00 0.00 C ATOM 639 C1' DG B 21 2.380 1.409 18.053 1.00 0.00 C ATOM 640 N9 DG B 21 3.529 2.040 17.363 1.00 0.00 N ATOM 641 C8 DG B 21 3.882 3.396 17.332 1.00 0.00 C ATOM 642 N7 DG B 21 5.015 3.563 16.704 1.00 0.00 N ATOM 643 C5 DG B 21 5.491 2.296 16.349 1.00 0.00 C ATOM 644 C6 DG B 21 6.729 1.785 15.746 1.00 0.00 C ATOM 645 O6 DG B 21 7.699 2.515 15.392 1.00 0.00 O ATOM 646 N1 DG B 21 6.819 0.487 15.679 1.00 0.00 N ATOM 647 C2 DG B 21 5.821 -0.342 16.035 1.00 0.00 C ATOM 648 N2 DG B 21 6.099 -1.651 15.875 1.00 0.00 N ATOM 649 N3 DG B 21 4.711 -0.005 16.696 1.00 0.00 N ATOM 650 C4 DG B 21 4.651 1.367 16.872 1.00 0.00 C ATOM 651 H5' DG B 21 -1.624 2.533 17.896 1.00 0.00 H ATOM 652 H5'' DG B 21 -1.787 1.849 19.483 1.00 0.00 H ATOM 653 H4' DG B 21 -0.085 0.543 18.245 1.00 0.00 H ATOM 654 H3' DG B 21 0.643 1.791 20.874 1.00 0.00 H ATOM 655 H2' DG B 21 2.600 2.657 19.779 1.00 0.00 H ATOM 656 H2'' DG B 21 3.092 0.957 19.934 1.00 0.00 H ATOM 657 H1' DG B 21 2.376 0.366 17.736 1.00 0.00 H ATOM 658 H8 DG B 21 3.292 4.227 17.693 1.00 0.00 H ATOM 659 H1 DG B 21 7.611 0.174 15.135 1.00 0.00 H ATOM 660 H21 DG B 21 5.555 -2.331 16.384 1.00 0.00 H ATOM 661 H22 DG B 21 6.913 -1.939 15.352 1.00 0.00 H ATOM 662 P DG B 22 1.374 -0.936 21.491 1.00 0.00 P ATOM 663 OP1 DG B 22 0.438 -1.941 21.982 1.00 0.00 O ATOM 664 OP2 DG B 22 1.833 0.076 22.422 1.00 0.00 O ATOM 665 O5' DG B 22 2.703 -1.602 20.884 1.00 0.00 O ATOM 666 C5' DG B 22 2.585 -2.649 19.946 1.00 0.00 C ATOM 667 C4' DG B 22 3.946 -3.206 19.431 1.00 0.00 C ATOM 668 O4' DG B 22 4.713 -2.099 18.924 1.00 0.00 O ATOM 669 C3' DG B 22 4.879 -3.823 20.521 1.00 0.00 C ATOM 670 O3' DG B 22 5.163 -5.163 20.347 1.00 0.00 O ATOM 671 C2' DG B 22 6.149 -3.045 20.534 1.00 0.00 C ATOM 672 C1' DG B 22 6.077 -2.402 19.199 1.00 0.00 C ATOM 673 N9 DG B 22 6.942 -1.140 19.294 1.00 0.00 N ATOM 674 C8 DG B 22 6.573 0.121 19.705 1.00 0.00 C ATOM 675 N7 DG B 22 7.388 1.103 19.377 1.00 0.00 N ATOM 676 C5 DG B 22 8.483 0.417 18.815 1.00 0.00 C ATOM 677 C6 DG B 22 9.632 0.896 18.090 1.00 0.00 C ATOM 678 O6 DG B 22 10.181 1.995 17.864 1.00 0.00 O ATOM 679 N1 DG B 22 10.413 -0.144 17.528 1.00 0.00 N ATOM 680 C2 DG B 22 10.156 -1.494 17.763 1.00 0.00 C ATOM 681 N2 DG B 22 10.984 -2.325 17.198 1.00 0.00 N ATOM 682 N3 DG B 22 9.071 -1.944 18.301 1.00 0.00 N ATOM 683 C4 DG B 22 8.256 -0.947 18.778 1.00 0.00 C ATOM 684 H5' DG B 22 1.904 -2.274 19.182 1.00 0.00 H ATOM 685 H5'' DG B 22 2.064 -3.471 20.436 1.00 0.00 H ATOM 686 H4' DG B 22 3.718 -3.904 18.625 1.00 0.00 H ATOM 687 H3' DG B 22 4.330 -3.748 21.459 1.00 0.00 H ATOM 688 HO3' DG B 22 5.662 -5.373 21.139 1.00 0.00 H ATOM 689 H2' DG B 22 6.062 -2.308 21.332 1.00 0.00 H ATOM 690 H2'' DG B 22 7.021 -3.696 20.604 1.00 0.00 H ATOM 691 H1' DG B 22 6.582 -3.044 18.477 1.00 0.00 H ATOM 692 H8 DG B 22 5.626 0.388 20.152 1.00 0.00 H ATOM 693 H1 DG B 22 11.058 0.172 16.819 1.00 0.00 H ATOM 694 H21 DG B 22 10.781 -3.307 17.078 1.00 0.00 H ATOM 695 H22 DG B 22 11.725 -1.967 16.613 1.00 0.00 H TER 696 DG B 22 HETATM 697 C14 2QL A 101 -3.923 -0.564 0.189 1.00 0.00 C HETATM 698 C13 2QL A 101 -5.051 -1.187 -0.612 1.00 0.00 C HETATM 699 O13 2QL A 101 -6.196 -1.169 0.229 1.00 0.00 O HETATM 700 C12 2QL A 101 -5.352 -0.367 -1.849 1.00 0.00 C HETATM 701 O12 2QL A 101 -6.656 -0.681 -2.284 1.00 0.00 O HETATM 702 C11 2QL A 101 -5.143 1.179 -1.695 1.00 0.00 C HETATM 703 O11 2QL A 101 -3.998 1.636 -2.426 1.00 0.00 O HETATM 704 C16 2QL A 101 -4.847 1.715 -0.289 1.00 0.00 C HETATM 705 C10 2QL A 101 -5.396 2.944 0.098 1.00 0.00 C HETATM 706 C17 2QL A 101 -5.521 3.191 1.430 1.00 0.00 C HETATM 707 C18 2QL A 101 -4.860 2.388 2.376 1.00 0.00 C HETATM 708 C9 2QL A 101 -6.349 4.264 1.817 1.00 0.00 C HETATM 709 C8 2QL A 101 -6.519 4.588 3.172 1.00 0.00 C HETATM 710 C20 2QL A 101 -5.804 3.850 4.120 1.00 0.00 C HETATM 711 C21 2QL A 101 -4.928 2.777 3.738 1.00 0.00 C HETATM 712 C7 2QL A 101 -5.843 4.262 5.472 1.00 0.00 C HETATM 713 C6 2QL A 101 -5.092 3.551 6.420 1.00 0.00 C HETATM 714 C5 2QL A 101 -4.279 2.437 6.057 1.00 0.00 C HETATM 715 C22 2QL A 101 -4.261 2.008 4.721 1.00 0.00 C HETATM 716 C23 2QL A 101 -3.425 0.892 4.341 1.00 0.00 C HETATM 717 C4 2QL A 101 -2.795 0.049 5.316 1.00 0.00 C HETATM 718 C3 2QL A 101 -1.820 -0.873 4.886 1.00 0.00 C HETATM 719 C2 2QL A 101 -1.357 -0.795 3.558 1.00 0.00 C HETATM 720 C1 2QL A 101 -2.032 -0.048 2.612 1.00 0.00 C HETATM 721 C24 2QL A 101 -3.178 0.706 2.947 1.00 0.00 C HETATM 722 C19 2QL A 101 -4.012 1.344 1.990 1.00 0.00 C HETATM 723 C15 2QL A 101 -4.115 0.901 0.595 1.00 0.00 C HETATM 724 H14 2QL A 101 -3.822 -1.114 1.125 1.00 0.00 H HETATM 725 H13 2QL A 101 -4.669 -2.173 -0.877 1.00 0.00 H HETATM 726 HO13 2QL A 101 -6.044 -1.703 1.013 1.00 0.00 H HETATM 727 H12 2QL A 101 -4.716 -0.705 -2.667 1.00 0.00 H HETATM 728 HO12 2QL A 101 -7.148 -0.797 -1.468 1.00 0.00 H HETATM 729 H11 2QL A 101 -6.046 1.659 -2.072 1.00 0.00 H HETATM 730 HO11 2QL A 101 -4.149 2.581 -2.508 1.00 0.00 H HETATM 731 H10 2QL A 101 -5.995 3.550 -0.566 1.00 0.00 H HETATM 732 H9 2QL A 101 -6.976 4.702 1.054 1.00 0.00 H HETATM 733 H8 2QL A 101 -7.194 5.382 3.455 1.00 0.00 H HETATM 734 H7 2QL A 101 -6.270 5.191 5.820 1.00 0.00 H HETATM 735 H6 2QL A 101 -5.014 3.952 7.420 1.00 0.00 H HETATM 736 H5 2QL A 101 -3.693 1.965 6.831 1.00 0.00 H HETATM 737 H4 2QL A 101 -3.044 0.138 6.363 1.00 0.00 H HETATM 738 H3 2QL A 101 -1.231 -1.558 5.477 1.00 0.00 H HETATM 739 H2 2QL A 101 -0.398 -1.198 3.267 1.00 0.00 H HETATM 740 H1 2QL A 101 -1.692 -0.115 1.589 1.00 0.00 H CONECT 172 697 CONECT 697 172 698 723 724 CONECT 698 697 699 700 725 CONECT 699 698 726 CONECT 700 698 701 702 727 CONECT 701 700 728 CONECT 702 700 703 704 729 CONECT 703 702 730 CONECT 704 702 705 723 CONECT 705 704 706 731 CONECT 706 705 707 708 CONECT 707 706 711 722 CONECT 708 706 709 732 CONECT 709 708 710 733 CONECT 710 709 711 712 CONECT 711 707 710 715 CONECT 712 710 713 734 CONECT 713 712 714 735 CONECT 714 713 715 736 CONECT 715 711 714 716 CONECT 716 715 717 721 CONECT 717 716 718 737 CONECT 718 717 719 738 CONECT 719 718 720 739 CONECT 720 719 721 740 CONECT 721 716 720 722 CONECT 722 707 721 723 CONECT 723 697 704 722 CONECT 724 697 CONECT 725 698 CONECT 726 699 CONECT 727 700 CONECT 728 701 CONECT 729 702 CONECT 730 703 CONECT 731 705 CONECT 732 708 CONECT 733 709 CONECT 734 712 CONECT 735 713 CONECT 736 714 CONECT 737 717 CONECT 738 718 CONECT 739 719 CONECT 740 720 MASTER 234 0 1 0 0 0 2 6 472 2 45 2 END