USER MOD reduce.3.24.130724 H: found=0, std=0, add=278, rem=0, adj=6 USER MOD reduce.3.24.130724 removed 278 hydrogens (28 hets) HEADER DNA 11-JUL-06 2HMR TITLE SOLUTION STRUCTURE OF REDUCED INTERSTRAND CROSS-LINK TITLE 2 ARISING FROM S-ALPHA-METHYL-GAMMA-OH-1,N2-PROPANO-2'- TITLE 3 DEOXYGUANOSINE IN THE 5'-CPG-3' DNA SEQUENCE COMPND MOL_ID: 1; COMPND 2 MOLECULE: DNA DODECAMER WITH INTERSTRAND CROSS-LINK; COMPND 3 CHAIN: A; COMPND 4 ENGINEERED: YES; COMPND 5 OTHER_DETAILS: G7 OF CHAIN A AND B LINKED; COMPND 6 MOL_ID: 2; COMPND 7 MOLECULE: DNA DODECAMER WITH INTERSTRAND CROSS-LINK; COMPND 8 CHAIN: B; COMPND 9 ENGINEERED: YES; COMPND 0 OTHER_DETAILS: G7 OF CHAIN A AND B LINKED SOURCE MOL_ID: 1; SOURCE 2 SYNTHETIC: YES; SOURCE 3 MOL_ID: 2; SOURCE 4 SYNTHETIC: YES KEYWDS CROTONALDEHYDE INTERSTRAND DNA CROSS-LINK EXPDTA SOLUTION NMR MDLTYP MINIMIZED AVERAGE AUTHOR Y.-J.CHO,I.D.KOZEKOV,T.M.HARRIS,C.J.RIZZO,M.P.STONE REVDAT 3 24-FEB-09 2HMR 1 VERSN REVDAT 2 10-APR-07 2HMR 1 JRNL REVDAT 1 13-MAR-07 2HMR 0 JRNL AUTH Y.-J.CHO,I.D.KOZEKOV,T.M.HARRIS,C.J.RIZZO,M.P.STONE JRNL TITL STEREOCHEMISTRY MODULATES THE STABILITY OF REDUCED JRNL TITL 2 INTERSTRAND CROSS-LINKS ARISING FROM R- AND JRNL TITL 3 S-ALPHA-CH(3)-GAMMA-OH-1,N(2)-PROPANO-2'- JRNL TITL 4 DEOXYGUANOSINE IN THE 5'-CPG-3' DNA SEQUENCE JRNL REF BIOCHEMISTRY V. 46 2608 2007 JRNL REFN ISSN 0006-2960 JRNL PMID 17305317 JRNL DOI 10.1021/BI061381H REMARK 1 REMARK 2 REMARK 2 RESOLUTION. NOT APPLICABLE. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : AMBER 8.0 REMARK 3 AUTHORS : CASE ET AL REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: NULL REMARK 4 REMARK 4 2HMR COMPLIES WITH FORMAT V. 3.15, 01-DEC-08 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 19-JUL-06. REMARK 100 THE RCSB ID CODE IS RCSB038523. REMARK 210 REMARK 210 EXPERIMENTAL DETAILS REMARK 210 EXPERIMENT TYPE : NMR REMARK 210 TEMPERATURE (KELVIN) : 303; 286 REMARK 210 PH : 7.0; 7.0 REMARK 210 IONIC STRENGTH : 0.1M NACL; 0.1M NACL REMARK 210 PRESSURE : 1 ATM; 1 ATM REMARK 210 SAMPLE CONTENTS : 2MM IN 0.25 ML; 10 MM REMARK 210 NAH2PO4; 0.1 M NACL; 50 UM REMARK 210 NA2EDTA; 2MM IN 0.25 ML; 10 MM REMARK 210 NAH2PO4; 0.1 M NACL; 50 UM REMARK 210 NA2EDTA REMARK 210 REMARK 210 NMR EXPERIMENTS CONDUCTED : 2D NOESY, DQF-COSY, 2D TOCSY REMARK 210 SPECTROMETER FIELD STRENGTH : 800 MHZ, 600 MHZ, 500 MHZ REMARK 210 SPECTROMETER MODEL : AVANCE REMARK 210 SPECTROMETER MANUFACTURER : BRUKER REMARK 210 REMARK 210 STRUCTURE DETERMINATION. REMARK 210 SOFTWARE USED : XWINNMR 3.5, NMRPIPE 2.3, REMARK 210 FELIX 2000, MARDIGRAS 5.2.1, REMARK 210 CORMA 5.2 REMARK 210 METHOD USED : DISTANCE GEOMETRY SIMULATED REMARK 210 ANNEALING MOLECULAR DYNAMICS REMARK 210 MATRIX RELAXATION REMARK 210 REMARK 210 CONFORMERS, NUMBER CALCULATED : 10 REMARK 210 CONFORMERS, NUMBER SUBMITTED : 1 REMARK 210 CONFORMERS, SELECTION CRITERIA : BACK CALCULATED DATA AGREE REMARK 210 WITH EXPERIMENTAL NOESY REMARK 210 SPECTRUM REMARK 210 REMARK 210 BEST REPRESENTATIVE CONFORMER IN THIS ENSEMBLE : 10 REMARK 210 REMARK 210 REMARK: THIS STRUCTURE WAS DETERMINED USING STANDARD 2D REMARK 210 HOMONUCLEAR TECHNIQUES. REMARK 215 REMARK 215 NMR STUDY REMARK 215 THE COORDINATES IN THIS ENTRY WERE GENERATED FROM SOLUTION REMARK 215 NMR DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE THAT REMARK 215 CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES ON REMARK 215 THESE RECORDS ARE MEANINGLESS. REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND ANGLES REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3 REMARK 500 DC A 2 N3 - C2 - O2 ANGL. DEV. = -4.8 DEGREES REMARK 500 DA A 4 C4 - C5 - C6 ANGL. DEV. = -3.6 DEGREES REMARK 500 DA A 4 C5 - C6 - N1 ANGL. DEV. = 4.2 DEGREES REMARK 500 DA A 4 N1 - C6 - N6 ANGL. DEV. = -5.1 DEGREES REMARK 500 DA A 8 O4' - C1' - N9 ANGL. DEV. = 3.2 DEGREES REMARK 500 DA A 8 C4 - C5 - C6 ANGL. DEV. = -3.2 DEGREES REMARK 500 DA A 8 C5 - C6 - N1 ANGL. DEV. = 3.7 DEGREES REMARK 500 DA A 8 N1 - C6 - N6 ANGL. DEV. = -5.9 DEGREES REMARK 500 DG A 9 O4' - C1' - N9 ANGL. DEV. = 4.0 DEGREES REMARK 500 DT A 10 O4' - C1' - N1 ANGL. DEV. = 4.5 DEGREES REMARK 500 DT A 10 N3 - C2 - O2 ANGL. DEV. = -3.7 DEGREES REMARK 500 DC A 11 O4' - C1' - N1 ANGL. DEV. = 3.3 DEGREES REMARK 500 DC A 11 N3 - C2 - O2 ANGL. DEV. = -5.1 DEGREES REMARK 500 DC A 12 O4' - C1' - N1 ANGL. DEV. = 2.6 DEGREES REMARK 500 DG B 14 N1 - C6 - O6 ANGL. DEV. = -3.9 DEGREES REMARK 500 DA B 15 O4' - C1' - N9 ANGL. DEV. = 3.3 DEGREES REMARK 500 DA B 15 C4 - C5 - C6 ANGL. DEV. = -3.4 DEGREES REMARK 500 DA B 15 C5 - C6 - N1 ANGL. DEV. = 4.1 DEGREES REMARK 500 DA B 15 N1 - C6 - N6 ANGL. DEV. = -4.1 DEGREES REMARK 500 DC B 16 O4' - C1' - N1 ANGL. DEV. = 4.4 DEGREES REMARK 500 DC B 16 N1 - C2 - O2 ANGL. DEV. = 3.6 DEGREES REMARK 500 DC B 16 N3 - C2 - O2 ANGL. DEV. = -5.1 DEGREES REMARK 500 DT B 17 C6 - C5 - C7 ANGL. DEV. = -3.9 DEGREES REMARK 500 DC B 18 N3 - C2 - O2 ANGL. DEV. = -4.9 DEGREES REMARK 500 DC B 20 N1 - C2 - O2 ANGL. DEV. = 3.7 DEGREES REMARK 500 DC B 20 N3 - C2 - O2 ANGL. DEV. = -5.3 DEGREES REMARK 500 DT B 21 O4' - C1' - N1 ANGL. DEV. = 3.9 DEGREES REMARK 500 DT B 21 C6 - C5 - C7 ANGL. DEV. = -3.6 DEGREES REMARK 500 DA B 22 O4' - C1' - N9 ANGL. DEV. = 5.0 DEGREES REMARK 500 DA B 22 C4 - C5 - C6 ANGL. DEV. = -3.6 DEGREES REMARK 500 DA B 22 C5 - C6 - N1 ANGL. DEV. = 4.1 DEGREES REMARK 500 DA B 22 N1 - C6 - N6 ANGL. DEV. = -4.8 DEGREES REMARK 500 DG B 23 N1 - C6 - O6 ANGL. DEV. = -3.8 DEGREES REMARK 500 DG B 23 C3' - O3' - P ANGL. DEV. = 8.2 DEGREES REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: PLANAR GROUPS REMARK 500 REMARK 500 PLANAR GROUPS IN THE FOLLOWING RESIDUES HAVE A TOTAL REMARK 500 RMS DISTANCE OF ALL ATOMS FROM THE BEST-FIT PLANE REMARK 500 BY MORE THAN AN EXPECTED VALUE OF 6*RMSD, WITH AN REMARK 500 RMSD 0.02 ANGSTROMS, OR AT LEAST ONE ATOM HAS REMARK 500 AN RMSD GREATER THAN THIS VALUE REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 M RES CSSEQI RMS TYPE REMARK 500 DC A 6 0.08 SIDE_CHAIN REMARK 500 DG B 13 0.07 SIDE_CHAIN REMARK 500 DG B 14 0.09 SIDE_CHAIN REMARK 500 DC B 18 0.06 SIDE_CHAIN REMARK 500 REMARK 500 REMARK: NULL REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 2HLI RELATED DB: PDB REMARK 900 S-METHYL STEREOCHEMISTRY BUT OPENED SPECIES (CROSS-LINK REMARK 900 PRECURSOR) REMARK 900 RELATED ID: 2HMD RELATED DB: PDB REMARK 900 R-METHYL STEREOCHEMISTRY DBREF 2HMR A 1 12 PDB 2HMR 2HMR 1 12 DBREF 2HMR B 13 24 PDB 2HMR 2HMR 13 24 SEQRES 1 A 12 DG DC DT DA DG DC 2EG DA DG DT DC DC SEQRES 1 B 12 DG DG DA DC DT DC 2EG DC DT DA DG DC MODRES 2HMR 2EG A 7 G 2'-DEOXY-N-ETHYLGUANOSINE 5'-PHOSPHATE MODRES 2HMR 2EG B 19 G 2'-DEOXY-N-ETHYLGUANOSINE 5'-PHOSPHATE HET 2EG A 7 38 HET 2EG B 19 38 HETNAM 2EG 2'-DEOXY-N-ETHYLGUANOSINE 5'-PHOSPHATE FORMUL 1 2EG 2(C12 H18 N5 O7 P) LINK C21 2EG A 7 C22 2EG B 19 1555 1555 1.56 LINK O3' DC A 6 P 2EG A 7 1555 1555 1.61 LINK O3' 2EG A 7 P DA A 8 1555 1555 1.61 LINK O3' DC B 18 P 2EG B 19 1555 1555 1.61 LINK O3' 2EG B 19 P DC B 20 1555 1555 1.61 CRYST1 1.000 1.000 1.000 90.00 90.00 90.00 P 1 1 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 1.000000 0.000000 0.000000 0.00000 SCALE2 0.000000 1.000000 0.000000 0.00000 SCALE3 0.000000 0.000000 1.000000 0.00000 USER MOD ----------------------------------------------------------------- USER MOD scores for adjustable sidechains, with "set" totals for H,N and Q USER MOD "o" means original, "f" means flipped, "180deg" is methyl default USER MOD "!" flags a clash with an overlap of 0.40A or greater USER MOD flip categories: "K"=keep, "C"=clashes, "X"=uncertain, "F"=flip USER MOD NoAdj-H: A 7 2EGH212 : A 7 2EG C21 : B 19 2EG C22 :(H bumps) USER MOD NoAdj-H: B 19 2EGH223 : B 19 2EG C22 : A 7 2EG C21 :(H bumps) USER MOD Single : A 1 DG O5' : rot 180:sc= 0 USER MOD Single : A 3 DT C7 :methyl 150:sc= -0.247 (180deg=-0.247) USER MOD Single : A 10 DT C7 :methyl 150:sc= -0.286 (180deg=-0.286) USER MOD Single : A 12 DC O3' : rot 180:sc= 0 USER MOD Single : B 13 DG O5' : rot -35:sc= 0.0715 USER MOD Single : B 17 DT C7 :methyl -30:sc= -0.361 (180deg=-0.554) USER MOD Single : B 21 DT C7 :methyl -30:sc= 0 (180deg=-0.152) USER MOD Single : B 24 DC O3' : rot 180:sc= 0 USER MOD ----------------------------------------------------------------- ATOM 1 O5' DG A 1 2.342 -8.580 -2.066 1.00 0.00 O ATOM 2 C5' DG A 1 3.599 -8.521 -2.734 1.00 0.00 C ATOM 3 C4' DG A 1 4.559 -7.489 -2.121 1.00 0.00 C ATOM 4 O4' DG A 1 4.026 -6.186 -2.312 1.00 0.00 O ATOM 5 C3' DG A 1 4.825 -7.694 -0.626 1.00 0.00 C ATOM 6 O3' DG A 1 6.210 -7.504 -0.409 1.00 0.00 O ATOM 7 C2' DG A 1 3.950 -6.622 0.011 1.00 0.00 C ATOM 8 C1' DG A 1 3.960 -5.530 -1.056 1.00 0.00 C ATOM 9 N9 DG A 1 2.745 -4.686 -1.023 1.00 0.00 N ATOM 10 C8 DG A 1 1.430 -5.071 -0.933 1.00 0.00 C ATOM 11 N7 DG A 1 0.573 -4.085 -0.966 1.00 0.00 N ATOM 12 C5 DG A 1 1.388 -2.951 -1.106 1.00 0.00 C ATOM 13 C6 DG A 1 1.078 -1.553 -1.255 1.00 0.00 C ATOM 14 O6 DG A 1 -0.016 -0.994 -1.327 1.00 0.00 O ATOM 15 N1 DG A 1 2.196 -0.752 -1.354 1.00 0.00 N ATOM 16 C2 DG A 1 3.465 -1.216 -1.312 1.00 0.00 C ATOM 17 N2 DG A 1 4.431 -0.341 -1.337 1.00 0.00 N ATOM 18 N3 DG A 1 3.803 -2.495 -1.222 1.00 0.00 N ATOM 19 C4 DG A 1 2.718 -3.318 -1.122 1.00 0.00 C ATOM 0 H5' DG A 1 3.435 -8.277 -3.784 1.00 0.00 H new ATOM 0 H5'' DG A 1 4.066 -9.505 -2.705 1.00 0.00 H new ATOM 0 H4' DG A 1 5.513 -7.618 -2.632 1.00 0.00 H new ATOM 0 H3' DG A 1 4.591 -8.677 -0.217 1.00 0.00 H new ATOM 0 H2' DG A 1 2.942 -6.985 0.214 1.00 0.00 H new ATOM 0 H2'' DG A 1 4.359 -6.271 0.958 1.00 0.00 H new ATOM 0 HO5' DG A 1 1.773 -9.250 -2.499 1.00 0.00 H new ATOM 0 H1' DG A 1 4.809 -4.870 -0.877 1.00 0.00 H new ATOM 0 H8 DG A 1 1.129 -6.104 -0.842 1.00 0.00 H new ATOM 0 H1 DG A 1 2.057 0.252 -1.466 1.00 0.00 H new ATOM 0 H21 DG A 1 5.402 -0.652 -1.307 1.00 0.00 H new ATOM 0 H22 DG A 1 4.216 0.655 -1.387 1.00 0.00 H new ATOM 32 P DC A 2 6.879 -7.594 1.049 1.00 0.00 P ATOM 33 OP1 DC A 2 8.237 -8.150 0.885 1.00 0.00 O ATOM 34 OP2 DC A 2 5.907 -8.231 1.964 1.00 0.00 O ATOM 35 O5' DC A 2 6.986 -6.019 1.376 1.00 0.00 O ATOM 36 C5' DC A 2 7.836 -5.194 0.589 1.00 0.00 C ATOM 37 C4' DC A 2 7.908 -3.733 1.046 1.00 0.00 C ATOM 38 O4' DC A 2 6.666 -3.062 0.848 1.00 0.00 O ATOM 39 C3' DC A 2 8.308 -3.571 2.514 1.00 0.00 C ATOM 40 O3' DC A 2 9.282 -2.544 2.579 1.00 0.00 O ATOM 41 C2' DC A 2 7.001 -3.128 3.155 1.00 0.00 C ATOM 42 C1' DC A 2 6.363 -2.320 2.021 1.00 0.00 C ATOM 43 N1 DC A 2 4.885 -2.174 2.130 1.00 0.00 N ATOM 44 C2 DC A 2 4.299 -0.901 2.090 1.00 0.00 C ATOM 45 O2 DC A 2 4.969 0.129 2.042 1.00 0.00 O ATOM 46 N3 DC A 2 2.950 -0.760 2.093 1.00 0.00 N ATOM 47 C4 DC A 2 2.205 -1.838 2.164 1.00 0.00 C ATOM 48 N4 DC A 2 0.922 -1.631 2.131 1.00 0.00 N ATOM 49 C5 DC A 2 2.732 -3.156 2.229 1.00 0.00 C ATOM 50 C6 DC A 2 4.084 -3.288 2.197 1.00 0.00 C ATOM 0 H5' DC A 2 7.491 -5.221 -0.445 1.00 0.00 H new ATOM 0 H5'' DC A 2 8.841 -5.615 0.601 1.00 0.00 H new ATOM 0 H4' DC A 2 8.686 -3.287 0.427 1.00 0.00 H new ATOM 0 H3' DC A 2 8.729 -4.455 2.992 1.00 0.00 H new ATOM 0 H2' DC A 2 6.383 -3.975 3.453 1.00 0.00 H new ATOM 0 H2'' DC A 2 7.166 -2.524 4.047 1.00 0.00 H new ATOM 0 H1' DC A 2 6.751 -1.302 2.034 1.00 0.00 H new ATOM 0 H41 DC A 2 0.277 -2.419 2.182 1.00 0.00 H new ATOM 0 H42 DC A 2 0.561 -0.680 2.055 1.00 0.00 H new ATOM 0 H5 DC A 2 2.085 -4.017 2.301 1.00 0.00 H new ATOM 0 H6 DC A 2 4.530 -4.271 2.224 1.00 0.00 H new ATOM 62 P DT A 3 10.112 -2.246 3.916 1.00 0.00 P ATOM 63 OP1 DT A 3 11.496 -1.935 3.509 1.00 0.00 O ATOM 64 OP2 DT A 3 9.837 -3.297 4.916 1.00 0.00 O ATOM 65 O5' DT A 3 9.426 -0.901 4.423 1.00 0.00 O ATOM 66 C5' DT A 3 9.747 0.325 3.800 1.00 0.00 C ATOM 67 C4' DT A 3 8.979 1.499 4.408 1.00 0.00 C ATOM 68 O4' DT A 3 7.592 1.318 4.146 1.00 0.00 O ATOM 69 C3' DT A 3 9.184 1.659 5.922 1.00 0.00 C ATOM 70 O3' DT A 3 9.446 3.023 6.187 1.00 0.00 O ATOM 71 C2' DT A 3 7.849 1.194 6.485 1.00 0.00 C ATOM 72 C1' DT A 3 6.882 1.545 5.349 1.00 0.00 C ATOM 73 N1 DT A 3 5.630 0.739 5.353 1.00 0.00 N ATOM 74 C2 DT A 3 4.417 1.415 5.190 1.00 0.00 C ATOM 75 O2 DT A 3 4.327 2.617 4.972 1.00 0.00 O ATOM 76 N3 DT A 3 3.272 0.665 5.280 1.00 0.00 N ATOM 77 C4 DT A 3 3.211 -0.688 5.524 1.00 0.00 C ATOM 78 O4 DT A 3 2.115 -1.234 5.625 1.00 0.00 O ATOM 79 C5 DT A 3 4.509 -1.348 5.634 1.00 0.00 C ATOM 80 C7 DT A 3 4.576 -2.847 5.870 1.00 0.00 C ATOM 81 C6 DT A 3 5.658 -0.630 5.539 1.00 0.00 C ATOM 0 H5' DT A 3 9.524 0.259 2.735 1.00 0.00 H new ATOM 0 H5'' DT A 3 10.818 0.507 3.890 1.00 0.00 H new ATOM 0 H4' DT A 3 9.368 2.406 3.945 1.00 0.00 H new ATOM 0 H3' DT A 3 10.015 1.100 6.353 1.00 0.00 H new ATOM 0 H2' DT A 3 7.849 0.126 6.705 1.00 0.00 H new ATOM 0 H2'' DT A 3 7.595 1.710 7.411 1.00 0.00 H new ATOM 0 H1' DT A 3 6.558 2.579 5.467 1.00 0.00 H new ATOM 0 H3 DT A 3 2.386 1.154 5.155 1.00 0.00 H new ATOM 0 H71 DT A 3 5.483 -3.246 5.417 1.00 0.00 H new ATOM 0 H72 DT A 3 4.587 -3.046 6.942 1.00 0.00 H new ATOM 0 H73 DT A 3 3.706 -3.325 5.421 1.00 0.00 H new ATOM 0 H6 DT A 3 6.609 -1.137 5.610 1.00 0.00 H new ATOM 94 P DA A 4 9.671 3.593 7.673 1.00 0.00 P ATOM 95 OP1 DA A 4 10.640 4.702 7.582 1.00 0.00 O ATOM 96 OP2 DA A 4 9.883 2.468 8.607 1.00 0.00 O ATOM 97 O5' DA A 4 8.219 4.203 7.922 1.00 0.00 O ATOM 98 C5' DA A 4 7.774 5.305 7.149 1.00 0.00 C ATOM 99 C4' DA A 4 6.420 5.823 7.629 1.00 0.00 C ATOM 100 O4' DA A 4 5.405 4.867 7.364 1.00 0.00 O ATOM 101 C3' DA A 4 6.420 6.134 9.130 1.00 0.00 C ATOM 102 O3' DA A 4 5.899 7.441 9.303 1.00 0.00 O ATOM 103 C2' DA A 4 5.524 5.030 9.687 1.00 0.00 C ATOM 104 C1' DA A 4 4.588 4.764 8.512 1.00 0.00 C ATOM 105 N9 DA A 4 3.985 3.415 8.537 1.00 0.00 N ATOM 106 C8 DA A 4 4.618 2.194 8.556 1.00 0.00 C ATOM 107 N7 DA A 4 3.814 1.161 8.507 1.00 0.00 N ATOM 108 C5 DA A 4 2.545 1.769 8.491 1.00 0.00 C ATOM 109 C6 DA A 4 1.210 1.304 8.442 1.00 0.00 C ATOM 110 N6 DA A 4 0.862 0.038 8.344 1.00 0.00 N ATOM 111 N1 DA A 4 0.175 2.139 8.446 1.00 0.00 N ATOM 112 C2 DA A 4 0.431 3.441 8.473 1.00 0.00 C ATOM 113 N3 DA A 4 1.621 4.031 8.495 1.00 0.00 N ATOM 114 C4 DA A 4 2.644 3.133 8.505 1.00 0.00 C ATOM 0 H5' DA A 4 7.700 5.009 6.103 1.00 0.00 H new ATOM 0 H5'' DA A 4 8.510 6.107 7.202 1.00 0.00 H new ATOM 0 H4' DA A 4 6.224 6.746 7.084 1.00 0.00 H new ATOM 0 H3' DA A 4 7.389 6.138 9.630 1.00 0.00 H new ATOM 0 H2' DA A 4 6.093 4.143 9.965 1.00 0.00 H new ATOM 0 H2'' DA A 4 4.982 5.353 10.576 1.00 0.00 H new ATOM 0 H1' DA A 4 3.757 5.469 8.539 1.00 0.00 H new ATOM 0 H8 DA A 4 5.692 2.095 8.607 1.00 0.00 H new ATOM 0 H61 DA A 4 -0.125 -0.219 8.314 1.00 0.00 H new ATOM 0 H62 DA A 4 1.579 -0.686 8.298 1.00 0.00 H new ATOM 0 H2 DA A 4 -0.427 4.097 8.478 1.00 0.00 H new ATOM 126 P DG A 5 5.840 8.154 10.738 1.00 0.00 P ATOM 127 OP1 DG A 5 6.017 9.607 10.545 1.00 0.00 O ATOM 128 OP2 DG A 5 6.715 7.421 11.675 1.00 0.00 O ATOM 129 O5' DG A 5 4.316 7.880 11.144 1.00 0.00 O ATOM 130 C5' DG A 5 3.267 8.530 10.445 1.00 0.00 C ATOM 131 C4' DG A 5 1.897 8.231 11.052 1.00 0.00 C ATOM 132 O4' DG A 5 1.539 6.880 10.810 1.00 0.00 O ATOM 133 C3' DG A 5 1.853 8.474 12.568 1.00 0.00 C ATOM 134 O3' DG A 5 0.638 9.150 12.840 1.00 0.00 O ATOM 135 C2' DG A 5 1.871 7.046 13.104 1.00 0.00 C ATOM 136 C1' DG A 5 1.070 6.325 12.022 1.00 0.00 C ATOM 137 N9 DG A 5 1.249 4.856 11.982 1.00 0.00 N ATOM 138 C8 DG A 5 2.405 4.116 11.979 1.00 0.00 C ATOM 139 N7 DG A 5 2.222 2.820 11.922 1.00 0.00 N ATOM 140 C5 DG A 5 0.822 2.697 11.842 1.00 0.00 C ATOM 141 C6 DG A 5 -0.046 1.547 11.726 1.00 0.00 C ATOM 142 O6 DG A 5 0.242 0.354 11.617 1.00 0.00 O ATOM 143 N1 DG A 5 -1.389 1.870 11.738 1.00 0.00 N ATOM 144 C2 DG A 5 -1.864 3.132 11.833 1.00 0.00 C ATOM 145 N2 DG A 5 -3.155 3.289 11.873 1.00 0.00 N ATOM 146 N3 DG A 5 -1.106 4.219 11.917 1.00 0.00 N ATOM 147 C4 DG A 5 0.230 3.939 11.910 1.00 0.00 C ATOM 0 H5' DG A 5 3.277 8.214 9.402 1.00 0.00 H new ATOM 0 H5'' DG A 5 3.439 9.606 10.454 1.00 0.00 H new ATOM 0 H4' DG A 5 1.195 8.914 10.574 1.00 0.00 H new ATOM 0 H3' DG A 5 2.651 9.077 13.001 1.00 0.00 H new ATOM 0 H2' DG A 5 2.883 6.653 13.200 1.00 0.00 H new ATOM 0 H2'' DG A 5 1.404 6.967 14.086 1.00 0.00 H new ATOM 0 H1' DG A 5 0.006 6.464 12.214 1.00 0.00 H new ATOM 0 H8 DG A 5 3.386 4.566 12.020 1.00 0.00 H new ATOM 0 H1 DG A 5 -2.064 1.109 11.671 1.00 0.00 H new ATOM 0 H21 DG A 5 -3.553 4.225 11.945 1.00 0.00 H new ATOM 0 H22 DG A 5 -3.769 2.476 11.833 1.00 0.00 H new ATOM 159 P DC A 6 0.296 9.816 14.255 1.00 0.00 P ATOM 160 OP1 DC A 6 -0.338 11.125 13.986 1.00 0.00 O ATOM 161 OP2 DC A 6 1.478 9.726 15.139 1.00 0.00 O ATOM 162 O5' DC A 6 -0.832 8.786 14.748 1.00 0.00 O ATOM 163 C5' DC A 6 -2.125 8.813 14.158 1.00 0.00 C ATOM 164 C4' DC A 6 -2.993 7.650 14.648 1.00 0.00 C ATOM 165 O4' DC A 6 -2.451 6.415 14.218 1.00 0.00 O ATOM 166 C3' DC A 6 -3.144 7.612 16.171 1.00 0.00 C ATOM 167 O3' DC A 6 -4.437 8.068 16.530 1.00 0.00 O ATOM 168 C2' DC A 6 -2.918 6.141 16.522 1.00 0.00 C ATOM 169 C1' DC A 6 -2.728 5.423 15.187 1.00 0.00 C ATOM 170 N1 DC A 6 -1.588 4.469 15.245 1.00 0.00 N ATOM 171 C2 DC A 6 -1.849 3.098 15.254 1.00 0.00 C ATOM 172 O2 DC A 6 -2.987 2.659 15.357 1.00 0.00 O ATOM 173 N3 DC A 6 -0.838 2.207 15.129 1.00 0.00 N ATOM 174 C4 DC A 6 0.400 2.652 15.099 1.00 0.00 C ATOM 175 N4 DC A 6 1.310 1.752 14.852 1.00 0.00 N ATOM 176 C5 DC A 6 0.741 4.033 15.172 1.00 0.00 C ATOM 177 C6 DC A 6 -0.289 4.918 15.249 1.00 0.00 C ATOM 0 H5' DC A 6 -2.031 8.766 13.073 1.00 0.00 H new ATOM 0 H5'' DC A 6 -2.614 9.758 14.395 1.00 0.00 H new ATOM 0 H4' DC A 6 -3.981 7.810 14.217 1.00 0.00 H new ATOM 0 H3' DC A 6 -2.447 8.256 16.707 1.00 0.00 H new ATOM 0 H2' DC A 6 -2.042 6.021 17.160 1.00 0.00 H new ATOM 0 H2'' DC A 6 -3.769 5.733 17.068 1.00 0.00 H new ATOM 0 H1' DC A 6 -3.626 4.855 14.943 1.00 0.00 H new ATOM 0 H41 DC A 6 2.294 2.019 14.812 1.00 0.00 H new ATOM 0 H42 DC A 6 1.038 0.781 14.698 1.00 0.00 H new ATOM 0 H5 DC A 6 1.770 4.362 15.166 1.00 0.00 H new ATOM 0 H6 DC A 6 -0.085 5.977 15.313 1.00 0.00 H new HETATM 189 OP1 2EG A 7 -5.934 9.281 18.132 1.00 0.00 O HETATM 190 P 2EG A 7 -4.845 8.285 18.068 1.00 0.00 P HETATM 191 OP2 2EG A 7 -3.622 8.486 18.875 1.00 0.00 O HETATM 192 O5' 2EG A 7 -5.440 6.866 18.469 1.00 0.00 O HETATM 193 C5' 2EG A 7 -6.775 6.462 18.193 1.00 0.00 C HETATM 194 C4' 2EG A 7 -7.117 5.242 19.068 1.00 0.00 C HETATM 195 O4' 2EG A 7 -6.272 4.189 18.623 1.00 0.00 O HETATM 196 C3' 2EG A 7 -6.826 5.568 20.559 1.00 0.00 C HETATM 197 O3' 2EG A 7 -7.619 5.090 21.648 1.00 0.00 O HETATM 198 C2' 2EG A 7 -5.450 4.937 20.722 1.00 0.00 C HETATM 199 C1' 2EG A 7 -5.429 3.798 19.687 1.00 0.00 C HETATM 200 N9 2EG A 7 -4.058 3.450 19.218 1.00 0.00 N HETATM 201 C4 2EG A 7 -3.658 2.215 18.747 1.00 0.00 C HETATM 202 N3 2EG A 7 -4.458 1.144 18.452 1.00 0.00 N HETATM 203 C8 2EG A 7 -2.896 4.186 19.309 1.00 0.00 C HETATM 204 N7 2EG A 7 -1.806 3.531 19.011 1.00 0.00 N HETATM 205 C5 2EG A 7 -2.283 2.262 18.666 1.00 0.00 C HETATM 206 C6 2EG A 7 -1.594 1.061 18.283 1.00 0.00 C HETATM 207 O6 2EG A 7 -0.386 0.847 18.197 1.00 0.00 O HETATM 208 N1 2EG A 7 -2.434 0.007 17.983 1.00 0.00 N HETATM 209 C2 2EG A 7 -3.794 0.071 18.010 1.00 0.00 C HETATM 210 N2 2EG A 7 -4.404 -0.991 17.488 1.00 0.00 N HETATM 211 C21 2EG A 7 -5.808 -1.141 17.060 1.00 0.00 C HETATM 212 C22 2EG A 7 -6.653 -1.394 18.299 1.00 0.00 C HETATM 0 H5'' 2EG A 7 -7.466 7.279 18.399 1.00 0.00 H new HETATM 0 H223 2EG A 7 -6.311 -2.304 18.793 1.00 0.00 H new HETATM 0 H222 2EG A 7 -6.557 -0.551 18.983 1.00 0.00 H new HETATM 0 H221 2EG A 7 -7.698 -1.509 18.010 1.00 0.00 H new HETATM 0 H211 2EG A 7 -5.906 -1.968 16.357 1.00 0.00 H new HETATM 0 H2'' 2EG A 7 -4.656 5.660 20.534 1.00 0.00 H new HETATM 0 H8 2EG A 7 -2.887 5.234 19.607 1.00 0.00 H new HETATM 0 H5' 2EG A 7 -6.883 6.211 17.138 1.00 0.00 H new HETATM 0 H4' 2EG A 7 -8.169 4.968 18.986 1.00 0.00 H new HETATM 0 H3' 2EG A 7 -7.007 6.638 20.660 1.00 0.00 H new HETATM 0 H21 2EG A 7 -3.818 -1.817 17.367 1.00 0.00 H new HETATM 0 H2' 2EG A 7 -5.303 4.558 21.733 1.00 0.00 H new HETATM 0 H1' 2EG A 7 -5.792 2.880 20.150 1.00 0.00 H new HETATM 0 H1 2EG A 7 -2.006 -0.882 17.723 1.00 0.00 H new ATOM 227 P DA A 8 -9.108 4.495 21.561 1.00 0.00 P ATOM 228 OP1 DA A 8 -9.852 5.102 20.437 1.00 0.00 O ATOM 229 OP2 DA A 8 -9.681 4.507 22.923 1.00 0.00 O ATOM 230 O5' DA A 8 -8.704 2.991 21.219 1.00 0.00 O ATOM 231 C5' DA A 8 -9.627 2.029 20.743 1.00 0.00 C ATOM 232 C4' DA A 8 -9.117 0.607 21.043 1.00 0.00 C ATOM 233 O4' DA A 8 -7.722 0.533 20.750 1.00 0.00 O ATOM 234 C3' DA A 8 -9.267 0.209 22.519 1.00 0.00 C ATOM 235 O3' DA A 8 -9.424 -1.195 22.626 1.00 0.00 O ATOM 236 C2' DA A 8 -7.889 0.531 23.068 1.00 0.00 C ATOM 237 C1' DA A 8 -7.040 0.046 21.894 1.00 0.00 C ATOM 238 N9 DA A 8 -5.636 0.516 21.931 1.00 0.00 N ATOM 239 C8 DA A 8 -5.150 1.748 22.293 1.00 0.00 C ATOM 240 N7 DA A 8 -3.848 1.870 22.204 1.00 0.00 N ATOM 241 C5 DA A 8 -3.447 0.592 21.783 1.00 0.00 C ATOM 242 C6 DA A 8 -2.206 -0.022 21.482 1.00 0.00 C ATOM 243 N6 DA A 8 -1.026 0.567 21.505 1.00 0.00 N ATOM 244 N1 DA A 8 -2.138 -1.295 21.095 1.00 0.00 N ATOM 245 C2 DA A 8 -3.273 -1.977 20.999 1.00 0.00 C ATOM 246 N3 DA A 8 -4.502 -1.550 21.252 1.00 0.00 N ATOM 247 C4 DA A 8 -4.526 -0.238 21.627 1.00 0.00 C ATOM 0 H5' DA A 8 -9.771 2.153 19.670 1.00 0.00 H new ATOM 0 H5'' DA A 8 -10.598 2.182 21.214 1.00 0.00 H new ATOM 0 H4' DA A 8 -9.718 -0.064 20.429 1.00 0.00 H new ATOM 0 H3' DA A 8 -10.108 0.698 23.011 1.00 0.00 H new ATOM 0 H2' DA A 8 -7.756 1.593 23.273 1.00 0.00 H new ATOM 0 H2'' DA A 8 -7.670 -0.002 23.993 1.00 0.00 H new ATOM 0 H1' DA A 8 -6.942 -1.039 21.909 1.00 0.00 H new ATOM 0 H8 DA A 8 -5.790 2.553 22.625 1.00 0.00 H new ATOM 0 H61 DA A 8 -0.187 0.037 21.271 1.00 0.00 H new ATOM 0 H62 DA A 8 -0.953 1.553 21.757 1.00 0.00 H new ATOM 0 H2 DA A 8 -3.184 -3.004 20.676 1.00 0.00 H new ATOM 259 P DG A 9 -10.776 -1.878 23.117 1.00 0.00 P ATOM 260 OP1 DG A 9 -11.742 -1.900 21.999 1.00 0.00 O ATOM 261 OP2 DG A 9 -11.152 -1.286 24.419 1.00 0.00 O ATOM 262 O5' DG A 9 -10.205 -3.366 23.375 1.00 0.00 O ATOM 263 C5' DG A 9 -9.512 -3.697 24.578 1.00 0.00 C ATOM 264 C4' DG A 9 -8.120 -4.320 24.356 1.00 0.00 C ATOM 265 O4' DG A 9 -7.139 -3.334 24.032 1.00 0.00 O ATOM 266 C3' DG A 9 -7.630 -4.995 25.653 1.00 0.00 C ATOM 267 O3' DG A 9 -7.426 -6.389 25.478 1.00 0.00 O ATOM 268 C2' DG A 9 -6.322 -4.273 25.957 1.00 0.00 C ATOM 269 C1' DG A 9 -5.902 -3.722 24.605 1.00 0.00 C ATOM 270 N9 DG A 9 -4.965 -2.579 24.748 1.00 0.00 N ATOM 271 C8 DG A 9 -5.257 -1.274 25.043 1.00 0.00 C ATOM 272 N7 DG A 9 -4.224 -0.477 25.081 1.00 0.00 N ATOM 273 C5 DG A 9 -3.142 -1.327 24.815 1.00 0.00 C ATOM 274 C6 DG A 9 -1.721 -1.084 24.722 1.00 0.00 C ATOM 275 O6 DG A 9 -1.091 -0.030 24.786 1.00 0.00 O ATOM 276 N1 DG A 9 -0.979 -2.231 24.533 1.00 0.00 N ATOM 277 C2 DG A 9 -1.516 -3.468 24.434 1.00 0.00 C ATOM 278 N2 DG A 9 -0.684 -4.466 24.338 1.00 0.00 N ATOM 279 N3 DG A 9 -2.816 -3.739 24.486 1.00 0.00 N ATOM 280 C4 DG A 9 -3.587 -2.624 24.664 1.00 0.00 C ATOM 0 H5' DG A 9 -10.121 -4.393 25.155 1.00 0.00 H new ATOM 0 H5'' DG A 9 -9.402 -2.795 25.180 1.00 0.00 H new ATOM 0 H4' DG A 9 -8.230 -5.030 23.536 1.00 0.00 H new ATOM 0 H3' DG A 9 -8.355 -4.920 26.464 1.00 0.00 H new ATOM 0 H2' DG A 9 -6.463 -3.478 26.689 1.00 0.00 H new ATOM 0 H2'' DG A 9 -5.573 -4.952 26.364 1.00 0.00 H new ATOM 0 H1' DG A 9 -5.356 -4.439 23.992 1.00 0.00 H new ATOM 0 H8 DG A 9 -6.264 -0.931 25.230 1.00 0.00 H new ATOM 0 H1 DG A 9 0.035 -2.141 24.464 1.00 0.00 H new ATOM 0 H21 DG A 9 -1.038 -5.419 24.261 1.00 0.00 H new ATOM 0 H22 DG A 9 0.321 -4.294 24.340 1.00 0.00 H new ATOM 292 P DT A 10 -7.276 -7.378 26.747 1.00 0.00 P ATOM 293 OP1 DT A 10 -7.718 -8.730 26.354 1.00 0.00 O ATOM 294 OP2 DT A 10 -7.891 -6.723 27.924 1.00 0.00 O ATOM 295 O5' DT A 10 -5.689 -7.389 26.997 1.00 0.00 O ATOM 296 C5' DT A 10 -4.780 -8.100 26.163 1.00 0.00 C ATOM 297 C4' DT A 10 -3.328 -7.999 26.678 1.00 0.00 C ATOM 298 O4' DT A 10 -2.841 -6.667 26.479 1.00 0.00 O ATOM 299 C3' DT A 10 -3.220 -8.301 28.188 1.00 0.00 C ATOM 300 O3' DT A 10 -1.980 -8.866 28.577 1.00 0.00 O ATOM 301 C2' DT A 10 -3.187 -6.893 28.756 1.00 0.00 C ATOM 302 C1' DT A 10 -2.278 -6.240 27.708 1.00 0.00 C ATOM 303 N1 DT A 10 -2.174 -4.757 27.811 1.00 0.00 N ATOM 304 C2 DT A 10 -0.891 -4.188 27.811 1.00 0.00 C ATOM 305 O2 DT A 10 0.151 -4.830 27.770 1.00 0.00 O ATOM 306 N3 DT A 10 -0.817 -2.823 27.948 1.00 0.00 N ATOM 307 C4 DT A 10 -1.875 -1.987 28.203 1.00 0.00 C ATOM 308 O4 DT A 10 -1.662 -0.797 28.397 1.00 0.00 O ATOM 309 C5 DT A 10 -3.180 -2.639 28.250 1.00 0.00 C ATOM 310 C7 DT A 10 -4.428 -1.820 28.530 1.00 0.00 C ATOM 311 C6 DT A 10 -3.293 -3.975 28.030 1.00 0.00 C ATOM 0 H5' DT A 10 -4.834 -7.706 25.148 1.00 0.00 H new ATOM 0 H5'' DT A 10 -5.076 -9.148 26.114 1.00 0.00 H new ATOM 0 H4' DT A 10 -2.745 -8.734 26.123 1.00 0.00 H new ATOM 0 H3' DT A 10 -4.005 -8.989 28.501 1.00 0.00 H new ATOM 0 H2' DT A 10 -4.174 -6.434 28.803 1.00 0.00 H new ATOM 0 H2'' DT A 10 -2.768 -6.853 29.762 1.00 0.00 H new ATOM 0 H1' DT A 10 -1.239 -6.543 27.837 1.00 0.00 H new ATOM 0 H3 DT A 10 0.103 -2.394 27.852 1.00 0.00 H new ATOM 0 H71 DT A 10 -5.283 -2.277 28.032 1.00 0.00 H new ATOM 0 H72 DT A 10 -4.609 -1.788 29.604 1.00 0.00 H new ATOM 0 H73 DT A 10 -4.289 -0.806 28.155 1.00 0.00 H new ATOM 0 H6 DT A 10 -4.271 -4.433 28.026 1.00 0.00 H new ATOM 324 P DC A 11 -1.633 -10.419 28.428 1.00 0.00 P ATOM 325 OP1 DC A 11 -1.865 -10.837 27.031 1.00 0.00 O ATOM 326 OP2 DC A 11 -2.298 -11.129 29.540 1.00 0.00 O ATOM 327 O5' DC A 11 -0.047 -10.358 28.712 1.00 0.00 O ATOM 328 C5' DC A 11 0.452 -10.187 30.031 1.00 0.00 C ATOM 329 C4' DC A 11 1.363 -8.962 30.179 1.00 0.00 C ATOM 330 O4' DC A 11 0.675 -7.729 29.992 1.00 0.00 O ATOM 331 C3' DC A 11 1.933 -8.910 31.607 1.00 0.00 C ATOM 332 O3' DC A 11 3.303 -9.283 31.623 1.00 0.00 O ATOM 333 C2' DC A 11 1.710 -7.451 32.017 1.00 0.00 C ATOM 334 C1' DC A 11 1.374 -6.736 30.713 1.00 0.00 C ATOM 335 N1 DC A 11 0.536 -5.523 30.931 1.00 0.00 N ATOM 336 C2 DC A 11 1.129 -4.254 30.928 1.00 0.00 C ATOM 337 O2 DC A 11 2.342 -4.097 30.819 1.00 0.00 O ATOM 338 N3 DC A 11 0.383 -3.140 31.110 1.00 0.00 N ATOM 339 C4 DC A 11 -0.910 -3.274 31.284 1.00 0.00 C ATOM 340 N4 DC A 11 -1.584 -2.171 31.399 1.00 0.00 N ATOM 341 C5 DC A 11 -1.572 -4.531 31.351 1.00 0.00 C ATOM 342 C6 DC A 11 -0.809 -5.641 31.176 1.00 0.00 C ATOM 0 H5' DC A 11 1.005 -11.080 30.322 1.00 0.00 H new ATOM 0 H5'' DC A 11 -0.387 -10.093 30.720 1.00 0.00 H new ATOM 0 H4' DC A 11 2.133 -9.072 29.415 1.00 0.00 H new ATOM 0 H3' DC A 11 1.456 -9.607 32.297 1.00 0.00 H new ATOM 0 H2' DC A 11 0.899 -7.361 32.740 1.00 0.00 H new ATOM 0 H2'' DC A 11 2.600 -7.029 32.483 1.00 0.00 H new ATOM 0 H1' DC A 11 2.256 -6.359 30.196 1.00 0.00 H new ATOM 0 H41 DC A 11 -2.594 -2.203 31.536 1.00 0.00 H new ATOM 0 H42 DC A 11 -1.103 -1.273 31.352 1.00 0.00 H new ATOM 0 H5 DC A 11 -2.634 -4.600 31.533 1.00 0.00 H new ATOM 0 H6 DC A 11 -1.262 -6.620 31.230 1.00 0.00 H new ATOM 354 P DC A 12 4.069 -9.685 32.989 1.00 0.00 P ATOM 355 OP1 DC A 12 5.356 -10.318 32.647 1.00 0.00 O ATOM 356 OP2 DC A 12 3.130 -10.361 33.908 1.00 0.00 O ATOM 357 O5' DC A 12 4.400 -8.230 33.580 1.00 0.00 O ATOM 358 C5' DC A 12 5.337 -7.392 32.919 1.00 0.00 C ATOM 359 C4' DC A 12 5.405 -5.989 33.530 1.00 0.00 C ATOM 360 O4' DC A 12 4.372 -5.141 33.067 1.00 0.00 O ATOM 361 C3' DC A 12 5.249 -5.946 35.049 1.00 0.00 C ATOM 362 O3' DC A 12 6.430 -6.331 35.726 1.00 0.00 O ATOM 363 C2' DC A 12 4.917 -4.476 35.275 1.00 0.00 C ATOM 364 C1' DC A 12 4.303 -4.029 33.940 1.00 0.00 C ATOM 365 N1 DC A 12 2.899 -3.569 34.103 1.00 0.00 N ATOM 366 C2 DC A 12 2.670 -2.200 34.249 1.00 0.00 C ATOM 367 O2 DC A 12 3.594 -1.392 34.263 1.00 0.00 O ATOM 368 N3 DC A 12 1.417 -1.724 34.406 1.00 0.00 N ATOM 369 C4 DC A 12 0.414 -2.570 34.398 1.00 0.00 C ATOM 370 N4 DC A 12 -0.766 -2.031 34.514 1.00 0.00 N ATOM 371 C5 DC A 12 0.577 -3.980 34.299 1.00 0.00 C ATOM 372 C6 DC A 12 1.847 -4.450 34.161 1.00 0.00 C ATOM 0 H5' DC A 12 5.069 -7.313 31.866 1.00 0.00 H new ATOM 0 H5'' DC A 12 6.324 -7.852 32.963 1.00 0.00 H new ATOM 0 H4' DC A 12 6.399 -5.662 33.226 1.00 0.00 H new ATOM 0 H3' DC A 12 4.499 -6.638 35.432 1.00 0.00 H new ATOM 0 H2' DC A 12 4.217 -4.346 36.100 1.00 0.00 H new ATOM 0 H2'' DC A 12 5.808 -3.898 35.519 1.00 0.00 H new ATOM 0 HO3' DC A 12 6.282 -6.286 36.694 1.00 0.00 H new ATOM 0 H1' DC A 12 4.853 -3.178 33.538 1.00 0.00 H new ATOM 0 H41 DC A 12 -1.598 -2.621 34.516 1.00 0.00 H new ATOM 0 H42 DC A 12 -0.858 -1.019 34.602 1.00 0.00 H new ATOM 0 H5 DC A 12 -0.271 -4.649 34.332 1.00 0.00 H new ATOM 0 H6 DC A 12 2.027 -5.513 34.097 1.00 0.00 H new TER 385 DC A 12 ATOM 386 O5' DG B 13 0.068 9.051 35.365 1.00 0.00 O ATOM 387 C5' DG B 13 0.614 9.167 34.062 1.00 0.00 C ATOM 388 C4' DG B 13 1.969 8.450 34.010 1.00 0.00 C ATOM 389 O4' DG B 13 1.768 7.118 34.472 1.00 0.00 O ATOM 390 C3' DG B 13 2.526 8.372 32.586 1.00 0.00 C ATOM 391 O3' DG B 13 3.938 8.464 32.667 1.00 0.00 O ATOM 392 C2' DG B 13 2.032 7.004 32.123 1.00 0.00 C ATOM 393 C1' DG B 13 2.076 6.210 33.424 1.00 0.00 C ATOM 394 N9 DG B 13 1.108 5.090 33.477 1.00 0.00 N ATOM 395 C8 DG B 13 -0.264 5.129 33.508 1.00 0.00 C ATOM 396 N7 DG B 13 -0.834 3.975 33.734 1.00 0.00 N ATOM 397 C5 DG B 13 0.249 3.085 33.817 1.00 0.00 C ATOM 398 C6 DG B 13 0.327 1.669 34.084 1.00 0.00 C ATOM 399 O6 DG B 13 -0.566 0.861 34.350 1.00 0.00 O ATOM 400 N1 DG B 13 1.622 1.184 34.073 1.00 0.00 N ATOM 401 C2 DG B 13 2.717 1.956 33.863 1.00 0.00 C ATOM 402 N2 DG B 13 3.876 1.372 33.792 1.00 0.00 N ATOM 403 N3 DG B 13 2.701 3.267 33.687 1.00 0.00 N ATOM 404 C4 DG B 13 1.435 3.771 33.652 1.00 0.00 C ATOM 0 H5' DG B 13 0.736 10.218 33.800 1.00 0.00 H new ATOM 0 H5'' DG B 13 -0.068 8.733 33.330 1.00 0.00 H new ATOM 0 H4' DG B 13 2.678 9.007 34.623 1.00 0.00 H new ATOM 0 H3' DG B 13 2.215 9.158 31.897 1.00 0.00 H new ATOM 0 H2' DG B 13 1.027 7.051 31.705 1.00 0.00 H new ATOM 0 H2'' DG B 13 2.676 6.573 31.357 1.00 0.00 H new ATOM 0 HO5' DG B 13 0.298 8.175 35.739 1.00 0.00 H new ATOM 0 H1' DG B 13 3.067 5.765 33.512 1.00 0.00 H new ATOM 0 H8 DG B 13 -0.826 6.039 33.358 1.00 0.00 H new ATOM 0 H1 DG B 13 1.762 0.186 34.232 1.00 0.00 H new ATOM 0 H21 DG B 13 4.718 1.926 33.635 1.00 0.00 H new ATOM 0 H22 DG B 13 3.944 0.359 33.894 1.00 0.00 H new ATOM 417 P DG B 14 4.851 8.694 31.360 1.00 0.00 P ATOM 418 OP1 DG B 14 6.087 9.372 31.792 1.00 0.00 O ATOM 419 OP2 DG B 14 3.996 9.299 30.315 1.00 0.00 O ATOM 420 O5' DG B 14 5.208 7.177 30.954 1.00 0.00 O ATOM 421 C5' DG B 14 6.112 6.412 31.746 1.00 0.00 C ATOM 422 C4' DG B 14 6.360 4.982 31.237 1.00 0.00 C ATOM 423 O4' DG B 14 5.232 4.141 31.475 1.00 0.00 O ATOM 424 C3' DG B 14 6.695 4.910 29.743 1.00 0.00 C ATOM 425 O3' DG B 14 7.764 3.982 29.573 1.00 0.00 O ATOM 426 C2' DG B 14 5.384 4.381 29.173 1.00 0.00 C ATOM 427 C1' DG B 14 4.977 3.413 30.283 1.00 0.00 C ATOM 428 N9 DG B 14 3.565 2.959 30.257 1.00 0.00 N ATOM 429 C8 DG B 14 2.419 3.698 30.107 1.00 0.00 C ATOM 430 N7 DG B 14 1.311 3.024 30.285 1.00 0.00 N ATOM 431 C5 DG B 14 1.757 1.718 30.536 1.00 0.00 C ATOM 432 C6 DG B 14 1.055 0.492 30.835 1.00 0.00 C ATOM 433 O6 DG B 14 -0.146 0.280 31.003 1.00 0.00 O ATOM 434 N1 DG B 14 1.886 -0.604 30.956 1.00 0.00 N ATOM 435 C2 DG B 14 3.229 -0.553 30.804 1.00 0.00 C ATOM 436 N2 DG B 14 3.872 -1.689 30.797 1.00 0.00 N ATOM 437 N3 DG B 14 3.928 0.556 30.595 1.00 0.00 N ATOM 438 C4 DG B 14 3.135 1.666 30.463 1.00 0.00 C ATOM 0 H5' DG B 14 5.726 6.359 32.764 1.00 0.00 H new ATOM 0 H5'' DG B 14 7.066 6.937 31.793 1.00 0.00 H new ATOM 0 H4' DG B 14 7.226 4.635 31.801 1.00 0.00 H new ATOM 0 H3' DG B 14 7.016 5.839 29.272 1.00 0.00 H new ATOM 0 H2' DG B 14 4.649 5.171 29.020 1.00 0.00 H new ATOM 0 H2'' DG B 14 5.519 3.881 28.214 1.00 0.00 H new ATOM 0 H1' DG B 14 5.537 2.484 30.177 1.00 0.00 H new ATOM 0 H8 DG B 14 2.430 4.750 29.862 1.00 0.00 H new ATOM 0 H1 DG B 14 1.462 -1.506 31.173 1.00 0.00 H new ATOM 0 H21 DG B 14 4.886 -1.701 30.685 1.00 0.00 H new ATOM 0 H22 DG B 14 3.361 -2.565 30.903 1.00 0.00 H new ATOM 450 P DA B 15 8.707 3.983 28.268 1.00 0.00 P ATOM 451 OP1 DA B 15 10.109 4.057 28.727 1.00 0.00 O ATOM 452 OP2 DA B 15 8.190 4.982 27.308 1.00 0.00 O ATOM 453 O5' DA B 15 8.456 2.533 27.639 1.00 0.00 O ATOM 454 C5' DA B 15 9.185 1.383 28.047 1.00 0.00 C ATOM 455 C4' DA B 15 8.719 0.106 27.318 1.00 0.00 C ATOM 456 O4' DA B 15 7.379 -0.156 27.726 1.00 0.00 O ATOM 457 C3' DA B 15 8.703 0.231 25.779 1.00 0.00 C ATOM 458 O3' DA B 15 8.710 -1.011 25.100 1.00 0.00 O ATOM 459 C2' DA B 15 7.296 0.730 25.530 1.00 0.00 C ATOM 460 C1' DA B 15 6.560 -0.119 26.572 1.00 0.00 C ATOM 461 N9 DA B 15 5.217 0.402 26.877 1.00 0.00 N ATOM 462 C8 DA B 15 4.746 1.688 26.774 1.00 0.00 C ATOM 463 N7 DA B 15 3.455 1.811 26.941 1.00 0.00 N ATOM 464 C5 DA B 15 3.061 0.490 27.211 1.00 0.00 C ATOM 465 C6 DA B 15 1.834 -0.140 27.504 1.00 0.00 C ATOM 466 N6 DA B 15 0.698 0.504 27.626 1.00 0.00 N ATOM 467 N1 DA B 15 1.752 -1.451 27.721 1.00 0.00 N ATOM 468 C2 DA B 15 2.869 -2.162 27.633 1.00 0.00 C ATOM 469 N3 DA B 15 4.093 -1.722 27.366 1.00 0.00 N ATOM 470 C4 DA B 15 4.123 -0.370 27.180 1.00 0.00 C ATOM 0 H5' DA B 15 9.072 1.247 29.123 1.00 0.00 H new ATOM 0 H5'' DA B 15 10.246 1.541 27.855 1.00 0.00 H new ATOM 0 H4' DA B 15 9.425 -0.683 27.577 1.00 0.00 H new ATOM 0 H3' DA B 15 9.559 0.820 25.449 1.00 0.00 H new ATOM 0 H2' DA B 15 7.190 1.800 25.707 1.00 0.00 H new ATOM 0 H2'' DA B 15 6.954 0.540 24.513 1.00 0.00 H new ATOM 0 H1' DA B 15 6.393 -1.123 26.182 1.00 0.00 H new ATOM 0 H8 DA B 15 5.391 2.531 26.571 1.00 0.00 H new ATOM 0 H61 DA B 15 -0.158 -0.008 27.839 1.00 0.00 H new ATOM 0 H62 DA B 15 0.671 1.517 27.508 1.00 0.00 H new ATOM 0 H2 DA B 15 2.771 -3.225 27.798 1.00 0.00 H new ATOM 482 P DC B 16 10.028 -1.839 24.779 1.00 0.00 P ATOM 483 OP1 DC B 16 10.661 -2.247 26.052 1.00 0.00 O ATOM 484 OP2 DC B 16 10.800 -1.095 23.765 1.00 0.00 O ATOM 485 O5' DC B 16 9.293 -3.104 24.102 1.00 0.00 O ATOM 486 C5' DC B 16 8.534 -4.031 24.876 1.00 0.00 C ATOM 487 C4' DC B 16 7.098 -4.283 24.367 1.00 0.00 C ATOM 488 O4' DC B 16 6.148 -3.297 24.759 1.00 0.00 O ATOM 489 C3' DC B 16 6.942 -4.429 22.852 1.00 0.00 C ATOM 490 O3' DC B 16 7.037 -5.791 22.484 1.00 0.00 O ATOM 491 C2' DC B 16 5.539 -3.868 22.600 1.00 0.00 C ATOM 492 C1' DC B 16 4.983 -3.526 23.979 1.00 0.00 C ATOM 493 N1 DC B 16 4.078 -2.341 23.934 1.00 0.00 N ATOM 494 C2 DC B 16 2.688 -2.507 24.034 1.00 0.00 C ATOM 495 O2 DC B 16 2.158 -3.614 24.114 1.00 0.00 O ATOM 496 N3 DC B 16 1.863 -1.433 24.034 1.00 0.00 N ATOM 497 C4 DC B 16 2.379 -0.235 23.876 1.00 0.00 C ATOM 498 N4 DC B 16 1.552 0.767 23.958 1.00 0.00 N ATOM 499 C5 DC B 16 3.775 -0.002 23.702 1.00 0.00 C ATOM 500 C6 DC B 16 4.595 -1.086 23.742 1.00 0.00 C ATOM 0 H5' DC B 16 8.481 -3.667 25.902 1.00 0.00 H new ATOM 0 H5'' DC B 16 9.066 -4.982 24.902 1.00 0.00 H new ATOM 0 H4' DC B 16 6.896 -5.238 24.851 1.00 0.00 H new ATOM 0 H3' DC B 16 7.708 -3.914 22.272 1.00 0.00 H new ATOM 0 H2' DC B 16 5.578 -2.985 21.963 1.00 0.00 H new ATOM 0 H2'' DC B 16 4.909 -4.599 22.093 1.00 0.00 H new ATOM 0 H1' DC B 16 4.358 -4.317 24.395 1.00 0.00 H new ATOM 0 H41 DC B 16 1.894 1.721 23.844 1.00 0.00 H new ATOM 0 H42 DC B 16 0.562 0.598 24.136 1.00 0.00 H new ATOM 0 H5 DC B 16 4.164 0.993 23.545 1.00 0.00 H new ATOM 0 H6 DC B 16 5.661 -0.957 23.622 1.00 0.00 H new ATOM 512 P DT B 17 6.950 -6.258 20.947 1.00 0.00 P ATOM 513 OP1 DT B 17 7.800 -7.454 20.789 1.00 0.00 O ATOM 514 OP2 DT B 17 7.130 -5.082 20.069 1.00 0.00 O ATOM 515 O5' DT B 17 5.414 -6.695 20.843 1.00 0.00 O ATOM 516 C5' DT B 17 4.897 -7.693 21.704 1.00 0.00 C ATOM 517 C4' DT B 17 3.379 -7.817 21.568 1.00 0.00 C ATOM 518 O4' DT B 17 2.768 -6.565 21.866 1.00 0.00 O ATOM 519 C3' DT B 17 2.937 -8.257 20.169 1.00 0.00 C ATOM 520 O3' DT B 17 1.944 -9.256 20.325 1.00 0.00 O ATOM 521 C2' DT B 17 2.382 -6.960 19.584 1.00 0.00 C ATOM 522 C1' DT B 17 1.852 -6.249 20.833 1.00 0.00 C ATOM 523 N1 DT B 17 1.747 -4.766 20.704 1.00 0.00 N ATOM 524 C2 DT B 17 0.510 -4.161 20.963 1.00 0.00 C ATOM 525 O2 DT B 17 -0.520 -4.782 21.189 1.00 0.00 O ATOM 526 N3 DT B 17 0.462 -2.786 20.925 1.00 0.00 N ATOM 527 C4 DT B 17 1.516 -1.957 20.616 1.00 0.00 C ATOM 528 O4 DT B 17 1.353 -0.741 20.656 1.00 0.00 O ATOM 529 C5 DT B 17 2.757 -2.649 20.262 1.00 0.00 C ATOM 530 C7 DT B 17 3.975 -1.859 19.815 1.00 0.00 C ATOM 531 C6 DT B 17 2.842 -4.004 20.340 1.00 0.00 C ATOM 0 H5' DT B 17 5.153 -7.453 22.736 1.00 0.00 H new ATOM 0 H5'' DT B 17 5.364 -8.651 21.474 1.00 0.00 H new ATOM 0 H4' DT B 17 3.064 -8.587 22.272 1.00 0.00 H new ATOM 0 H3' DT B 17 3.709 -8.687 19.531 1.00 0.00 H new ATOM 0 H2' DT B 17 3.153 -6.378 19.079 1.00 0.00 H new ATOM 0 H2'' DT B 17 1.594 -7.146 18.855 1.00 0.00 H new ATOM 0 H1' DT B 17 0.834 -6.587 21.023 1.00 0.00 H new ATOM 0 H3 DT B 17 -0.431 -2.344 21.145 1.00 0.00 H new ATOM 0 H71 DT B 17 3.653 -0.945 19.316 1.00 0.00 H new ATOM 0 H72 DT B 17 4.582 -1.604 20.684 1.00 0.00 H new ATOM 0 H73 DT B 17 4.565 -2.461 19.124 1.00 0.00 H new ATOM 0 H6 DT B 17 3.779 -4.492 20.114 1.00 0.00 H new ATOM 544 P DC B 18 1.541 -10.263 19.135 1.00 0.00 P ATOM 545 OP1 DC B 18 0.866 -11.432 19.733 1.00 0.00 O ATOM 546 OP2 DC B 18 2.715 -10.452 18.257 1.00 0.00 O ATOM 547 O5' DC B 18 0.445 -9.372 18.371 1.00 0.00 O ATOM 548 C5' DC B 18 -0.842 -9.187 18.939 1.00 0.00 C ATOM 549 C4' DC B 18 -1.705 -8.171 18.180 1.00 0.00 C ATOM 550 O4' DC B 18 -1.271 -6.837 18.398 1.00 0.00 O ATOM 551 C3' DC B 18 -1.775 -8.389 16.663 1.00 0.00 C ATOM 552 O3' DC B 18 -2.956 -9.121 16.349 1.00 0.00 O ATOM 553 C2' DC B 18 -1.759 -6.950 16.123 1.00 0.00 C ATOM 554 C1' DC B 18 -1.801 -6.041 17.359 1.00 0.00 C ATOM 555 N1 DC B 18 -0.983 -4.799 17.240 1.00 0.00 N ATOM 556 C2 DC B 18 -1.596 -3.542 17.347 1.00 0.00 C ATOM 557 O2 DC B 18 -2.818 -3.412 17.391 1.00 0.00 O ATOM 558 N3 DC B 18 -0.855 -2.412 17.423 1.00 0.00 N ATOM 559 C4 DC B 18 0.452 -2.515 17.341 1.00 0.00 C ATOM 560 N4 DC B 18 1.135 -1.423 17.487 1.00 0.00 N ATOM 561 C5 DC B 18 1.140 -3.754 17.207 1.00 0.00 C ATOM 562 C6 DC B 18 0.386 -4.878 17.153 1.00 0.00 C ATOM 0 H5' DC B 18 -0.731 -8.857 19.972 1.00 0.00 H new ATOM 0 H5'' DC B 18 -1.361 -10.145 18.964 1.00 0.00 H new ATOM 0 H4' DC B 18 -2.701 -8.335 18.592 1.00 0.00 H new ATOM 0 H3' DC B 18 -0.968 -8.978 16.228 1.00 0.00 H new ATOM 0 H2' DC B 18 -0.863 -6.764 15.531 1.00 0.00 H new ATOM 0 H2'' DC B 18 -2.614 -6.766 15.473 1.00 0.00 H new ATOM 0 H1' DC B 18 -2.822 -5.694 17.519 1.00 0.00 H new ATOM 0 H41 DC B 18 2.153 -1.447 17.432 1.00 0.00 H new ATOM 0 H42 DC B 18 0.654 -0.540 17.657 1.00 0.00 H new ATOM 0 H5 DC B 18 2.218 -3.796 17.151 1.00 0.00 H new ATOM 0 H6 DC B 18 0.863 -5.840 17.041 1.00 0.00 H new HETATM 574 OP1 2EG B 19 -4.254 -10.759 14.952 1.00 0.00 O HETATM 575 P 2EG B 19 -3.278 -9.655 14.862 1.00 0.00 P HETATM 576 OP2 2EG B 19 -2.018 -9.820 14.109 1.00 0.00 O HETATM 577 O5' 2EG B 19 -4.042 -8.384 14.262 1.00 0.00 O HETATM 578 C5' 2EG B 19 -5.274 -7.954 14.816 1.00 0.00 C HETATM 579 C4' 2EG B 19 -5.735 -6.642 14.180 1.00 0.00 C HETATM 580 O4' 2EG B 19 -4.892 -5.576 14.616 1.00 0.00 O HETATM 581 C3' 2EG B 19 -5.721 -6.686 12.643 1.00 0.00 C HETATM 582 O3' 2EG B 19 -6.936 -6.113 12.189 1.00 0.00 O HETATM 583 C2' 2EG B 19 -4.488 -5.844 12.337 1.00 0.00 C HETATM 584 C1' 2EG B 19 -4.495 -4.830 13.481 1.00 0.00 C HETATM 585 N9 2EG B 19 -3.185 -4.169 13.710 1.00 0.00 N HETATM 586 C4 2EG B 19 -3.006 -2.842 14.020 1.00 0.00 C HETATM 587 N3 2EG B 19 -3.992 -1.928 14.232 1.00 0.00 N HETATM 588 C8 2EG B 19 -1.917 -4.680 13.578 1.00 0.00 C HETATM 589 N7 2EG B 19 -0.960 -3.805 13.744 1.00 0.00 N HETATM 590 C5 2EG B 19 -1.648 -2.617 14.048 1.00 0.00 C HETATM 591 C6 2EG B 19 -1.189 -1.286 14.372 1.00 0.00 C HETATM 592 O6 2EG B 19 -0.036 -0.863 14.500 1.00 0.00 O HETATM 593 N1 2EG B 19 -2.216 -0.383 14.573 1.00 0.00 N HETATM 594 C2 2EG B 19 -3.544 -0.691 14.494 1.00 0.00 C HETATM 595 N2 2EG B 19 -4.410 0.300 14.709 1.00 0.00 N HETATM 596 C21 2EG B 19 -5.879 0.155 14.773 1.00 0.00 C HETATM 597 C22 2EG B 19 -6.396 0.028 16.218 1.00 0.00 C HETATM 0 H5'' 2EG B 19 -6.033 -8.722 14.664 1.00 0.00 H new HETATM 0 H222 2EG B 19 -6.122 0.919 16.782 1.00 0.00 H new HETATM 0 H221 2EG B 19 -7.481 -0.076 16.208 1.00 0.00 H new HETATM 0 H212 2EG B 19 -6.347 1.017 14.297 1.00 0.00 H new HETATM 0 H211 2EG B 19 -6.179 -0.725 14.204 1.00 0.00 H new HETATM 0 H2'' 2EG B 19 -3.578 -6.443 12.330 1.00 0.00 H new HETATM 0 H8 2EG B 19 -1.724 -5.729 13.353 1.00 0.00 H new HETATM 0 H5' 2EG B 19 -5.166 -7.822 15.893 1.00 0.00 H new HETATM 0 H4' 2EG B 19 -6.765 -6.482 14.498 1.00 0.00 H new HETATM 0 H3' 2EG B 19 -5.664 -7.665 12.167 1.00 0.00 H new HETATM 0 H21 2EG B 19 -4.026 1.236 14.840 1.00 0.00 H new HETATM 0 H2' 2EG B 19 -4.558 -5.359 11.363 1.00 0.00 H new HETATM 0 H1' 2EG B 19 -5.167 -4.003 13.250 1.00 0.00 H new HETATM 0 H1 2EG B 19 -1.964 0.580 14.796 1.00 0.00 H new ATOM 612 P DC B 20 -7.400 -6.046 10.647 1.00 0.00 P ATOM 613 OP1 DC B 20 -8.677 -6.781 10.497 1.00 0.00 O ATOM 614 OP2 DC B 20 -6.253 -6.335 9.761 1.00 0.00 O ATOM 615 O5' DC B 20 -7.685 -4.465 10.567 1.00 0.00 O ATOM 616 C5' DC B 20 -8.654 -3.852 11.415 1.00 0.00 C ATOM 617 C4' DC B 20 -8.604 -2.319 11.353 1.00 0.00 C ATOM 618 O4' DC B 20 -7.366 -1.877 11.898 1.00 0.00 O ATOM 619 C3' DC B 20 -8.732 -1.798 9.913 1.00 0.00 C ATOM 620 O3' DC B 20 -9.864 -0.974 9.620 1.00 0.00 O ATOM 621 C2' DC B 20 -7.383 -1.146 9.644 1.00 0.00 C ATOM 622 C1' DC B 20 -6.739 -0.957 11.021 1.00 0.00 C ATOM 623 N1 DC B 20 -5.277 -1.258 10.987 1.00 0.00 N ATOM 624 C2 DC B 20 -4.349 -0.235 11.221 1.00 0.00 C ATOM 625 O2 DC B 20 -4.685 0.921 11.453 1.00 0.00 O ATOM 626 N3 DC B 20 -3.020 -0.479 11.163 1.00 0.00 N ATOM 627 C4 DC B 20 -2.621 -1.697 10.887 1.00 0.00 C ATOM 628 N4 DC B 20 -1.337 -1.891 10.903 1.00 0.00 N ATOM 629 C5 DC B 20 -3.499 -2.773 10.596 1.00 0.00 C ATOM 630 C6 DC B 20 -4.830 -2.519 10.671 1.00 0.00 C ATOM 0 H5' DC B 20 -8.490 -4.176 12.443 1.00 0.00 H new ATOM 0 H5'' DC B 20 -9.649 -4.192 11.129 1.00 0.00 H new ATOM 0 H4' DC B 20 -9.445 -1.930 11.926 1.00 0.00 H new ATOM 0 H3' DC B 20 -8.951 -2.618 9.229 1.00 0.00 H new ATOM 0 H2' DC B 20 -6.764 -1.775 9.004 1.00 0.00 H new ATOM 0 H2'' DC B 20 -7.503 -0.191 9.133 1.00 0.00 H new ATOM 0 H1' DC B 20 -6.863 0.077 11.343 1.00 0.00 H new ATOM 0 H41 DC B 20 -0.958 -2.815 10.697 1.00 0.00 H new ATOM 0 H42 DC B 20 -0.707 -1.119 11.121 1.00 0.00 H new ATOM 0 H5 DC B 20 -3.125 -3.750 10.327 1.00 0.00 H new ATOM 0 H6 DC B 20 -5.540 -3.310 10.482 1.00 0.00 H new ATOM 642 P DT B 21 -10.229 0.446 10.306 1.00 0.00 P ATOM 643 OP1 DT B 21 -9.932 0.374 11.750 1.00 0.00 O ATOM 644 OP2 DT B 21 -11.582 0.829 9.860 1.00 0.00 O ATOM 645 O5' DT B 21 -9.189 1.473 9.633 1.00 0.00 O ATOM 646 C5' DT B 21 -8.826 2.675 10.292 1.00 0.00 C ATOM 647 C4' DT B 21 -7.663 3.399 9.600 1.00 0.00 C ATOM 648 O4' DT B 21 -6.503 2.573 9.638 1.00 0.00 O ATOM 649 C3' DT B 21 -7.911 3.792 8.128 1.00 0.00 C ATOM 650 O3' DT B 21 -7.485 5.140 7.935 1.00 0.00 O ATOM 651 C2' DT B 21 -6.993 2.798 7.413 1.00 0.00 C ATOM 652 C1' DT B 21 -5.839 2.749 8.408 1.00 0.00 C ATOM 653 N1 DT B 21 -4.802 1.704 8.174 1.00 0.00 N ATOM 654 C2 DT B 21 -3.472 2.073 8.409 1.00 0.00 C ATOM 655 O2 DT B 21 -3.122 3.208 8.704 1.00 0.00 O ATOM 656 N3 DT B 21 -2.514 1.110 8.233 1.00 0.00 N ATOM 657 C4 DT B 21 -2.725 -0.146 7.722 1.00 0.00 C ATOM 658 O4 DT B 21 -1.763 -0.888 7.535 1.00 0.00 O ATOM 659 C5 DT B 21 -4.125 -0.463 7.439 1.00 0.00 C ATOM 660 C7 DT B 21 -4.500 -1.827 6.885 1.00 0.00 C ATOM 661 C6 DT B 21 -5.104 0.449 7.678 1.00 0.00 C ATOM 0 H5' DT B 21 -8.548 2.451 11.322 1.00 0.00 H new ATOM 0 H5'' DT B 21 -9.690 3.338 10.332 1.00 0.00 H new ATOM 0 H4' DT B 21 -7.542 4.329 10.155 1.00 0.00 H new ATOM 0 H3' DT B 21 -8.945 3.752 7.785 1.00 0.00 H new ATOM 0 H2' DT B 21 -7.462 1.825 7.270 1.00 0.00 H new ATOM 0 H2'' DT B 21 -6.682 3.150 6.429 1.00 0.00 H new ATOM 0 H1' DT B 21 -5.233 3.652 8.336 1.00 0.00 H new ATOM 0 H3 DT B 21 -1.560 1.347 8.506 1.00 0.00 H new ATOM 0 H71 DT B 21 -3.677 -2.215 6.285 1.00 0.00 H new ATOM 0 H72 DT B 21 -4.702 -2.511 7.709 1.00 0.00 H new ATOM 0 H73 DT B 21 -5.390 -1.735 6.263 1.00 0.00 H new ATOM 0 H6 DT B 21 -6.133 0.190 7.478 1.00 0.00 H new ATOM 674 P DA B 22 -7.801 5.977 6.582 1.00 0.00 P ATOM 675 OP1 DA B 22 -9.093 6.661 6.772 1.00 0.00 O ATOM 676 OP2 DA B 22 -7.613 5.083 5.421 1.00 0.00 O ATOM 677 O5' DA B 22 -6.622 7.080 6.528 1.00 0.00 O ATOM 678 C5' DA B 22 -5.284 6.741 6.867 1.00 0.00 C ATOM 679 C4' DA B 22 -4.172 7.332 5.970 1.00 0.00 C ATOM 680 O4' DA B 22 -3.109 6.396 6.135 1.00 0.00 O ATOM 681 C3' DA B 22 -4.453 7.357 4.450 1.00 0.00 C ATOM 682 O3' DA B 22 -3.461 8.030 3.678 1.00 0.00 O ATOM 683 C2' DA B 22 -4.241 5.893 4.120 1.00 0.00 C ATOM 684 C1' DA B 22 -2.961 5.662 4.930 1.00 0.00 C ATOM 685 N9 DA B 22 -2.662 4.232 5.150 1.00 0.00 N ATOM 686 C8 DA B 22 -3.516 3.152 5.153 1.00 0.00 C ATOM 687 N7 DA B 22 -2.920 1.986 5.170 1.00 0.00 N ATOM 688 C5 DA B 22 -1.560 2.345 5.201 1.00 0.00 C ATOM 689 C6 DA B 22 -0.338 1.634 5.224 1.00 0.00 C ATOM 690 N6 DA B 22 -0.243 0.320 5.259 1.00 0.00 N ATOM 691 N1 DA B 22 0.838 2.259 5.231 1.00 0.00 N ATOM 692 C2 DA B 22 0.834 3.587 5.232 1.00 0.00 C ATOM 693 N3 DA B 22 -0.223 4.386 5.197 1.00 0.00 N ATOM 694 C4 DA B 22 -1.398 3.700 5.198 1.00 0.00 C ATOM 0 H5' DA B 22 -5.193 5.655 6.851 1.00 0.00 H new ATOM 0 H5'' DA B 22 -5.101 7.061 7.893 1.00 0.00 H new ATOM 0 H4' DA B 22 -4.014 8.370 6.262 1.00 0.00 H new ATOM 0 H3' DA B 22 -5.409 7.836 4.239 1.00 0.00 H new ATOM 0 H2' DA B 22 -5.068 5.262 4.446 1.00 0.00 H new ATOM 0 H2'' DA B 22 -4.105 5.715 3.053 1.00 0.00 H new ATOM 0 H1' DA B 22 -2.091 6.016 4.376 1.00 0.00 H new ATOM 0 H8 DA B 22 -4.591 3.258 5.142 1.00 0.00 H new ATOM 0 H61 DA B 22 0.675 -0.125 5.274 1.00 0.00 H new ATOM 0 H62 DA B 22 -1.087 -0.252 5.271 1.00 0.00 H new ATOM 0 H2 DA B 22 1.800 4.070 5.265 1.00 0.00 H new ATOM 706 P DG B 23 -3.426 9.610 3.462 1.00 0.00 P ATOM 707 OP1 DG B 23 -3.378 10.285 4.774 1.00 0.00 O ATOM 708 OP2 DG B 23 -4.473 9.953 2.478 1.00 0.00 O ATOM 709 O5' DG B 23 -1.982 9.737 2.750 1.00 0.00 O ATOM 710 C5' DG B 23 -0.774 9.814 3.507 1.00 0.00 C ATOM 711 C4' DG B 23 0.457 9.195 2.807 1.00 0.00 C ATOM 712 O4' DG B 23 0.451 7.798 3.079 1.00 0.00 O ATOM 713 C3' DG B 23 0.509 9.357 1.268 1.00 0.00 C ATOM 714 O3' DG B 23 1.520 10.185 0.669 1.00 0.00 O ATOM 715 C2' DG B 23 0.552 7.913 0.767 1.00 0.00 C ATOM 716 C1' DG B 23 0.991 7.094 1.983 1.00 0.00 C ATOM 717 N9 DG B 23 0.422 5.719 1.974 1.00 0.00 N ATOM 718 C8 DG B 23 -0.903 5.353 1.967 1.00 0.00 C ATOM 719 N7 DG B 23 -1.111 4.063 1.881 1.00 0.00 N ATOM 720 C5 DG B 23 0.183 3.521 1.902 1.00 0.00 C ATOM 721 C6 DG B 23 0.661 2.157 1.878 1.00 0.00 C ATOM 722 O6 DG B 23 0.038 1.096 1.839 1.00 0.00 O ATOM 723 N1 DG B 23 2.035 2.054 1.882 1.00 0.00 N ATOM 724 C2 DG B 23 2.869 3.116 1.919 1.00 0.00 C ATOM 725 N2 DG B 23 4.146 2.865 1.897 1.00 0.00 N ATOM 726 N3 DG B 23 2.484 4.387 1.912 1.00 0.00 N ATOM 727 C4 DG B 23 1.124 4.532 1.934 1.00 0.00 C ATOM 0 H5' DG B 23 -0.925 9.311 4.462 1.00 0.00 H new ATOM 0 H5'' DG B 23 -0.564 10.860 3.728 1.00 0.00 H new ATOM 0 H4' DG B 23 1.320 9.731 3.201 1.00 0.00 H new ATOM 0 H3' DG B 23 -0.356 9.943 0.959 1.00 0.00 H new ATOM 0 H2' DG B 23 -0.424 7.591 0.403 1.00 0.00 H new ATOM 0 H2'' DG B 23 1.253 7.801 -0.060 1.00 0.00 H new ATOM 0 H1' DG B 23 2.075 6.980 2.007 1.00 0.00 H new ATOM 0 H8 DG B 23 -1.707 6.071 2.028 1.00 0.00 H new ATOM 0 H1 DG B 23 2.447 1.121 1.855 1.00 0.00 H new ATOM 0 H21 DG B 23 4.817 3.633 1.923 1.00 0.00 H new ATOM 0 H22 DG B 23 4.475 1.901 1.854 1.00 0.00 H new ATOM 739 P DC B 24 3.123 10.124 0.900 1.00 0.00 P ATOM 740 OP1 DC B 24 3.418 10.080 2.339 1.00 0.00 O ATOM 741 OP2 DC B 24 3.713 11.196 0.067 1.00 0.00 O ATOM 742 O5' DC B 24 3.612 8.732 0.258 1.00 0.00 O ATOM 743 C5' DC B 24 3.795 8.604 -1.137 1.00 0.00 C ATOM 744 C4' DC B 24 4.293 7.201 -1.491 1.00 0.00 C ATOM 745 O4' DC B 24 3.461 6.203 -0.946 1.00 0.00 O ATOM 746 C3' DC B 24 4.223 6.951 -3.001 1.00 0.00 C ATOM 747 O3' DC B 24 5.391 7.364 -3.689 1.00 0.00 O ATOM 748 C2' DC B 24 4.039 5.438 -3.097 1.00 0.00 C ATOM 749 C1' DC B 24 3.658 5.010 -1.672 1.00 0.00 C ATOM 750 N1 DC B 24 2.417 4.194 -1.629 1.00 0.00 N ATOM 751 C2 DC B 24 2.529 2.813 -1.797 1.00 0.00 C ATOM 752 O2 DC B 24 3.613 2.281 -2.038 1.00 0.00 O ATOM 753 N3 DC B 24 1.445 2.015 -1.696 1.00 0.00 N ATOM 754 C4 DC B 24 0.281 2.572 -1.429 1.00 0.00 C ATOM 755 N4 DC B 24 -0.727 1.775 -1.241 1.00 0.00 N ATOM 756 C5 DC B 24 0.092 3.971 -1.280 1.00 0.00 C ATOM 757 C6 DC B 24 1.192 4.759 -1.381 1.00 0.00 C ATOM 0 H5' DC B 24 4.512 9.348 -1.484 1.00 0.00 H new ATOM 0 H5'' DC B 24 2.855 8.802 -1.652 1.00 0.00 H new ATOM 0 H4' DC B 24 5.310 7.153 -1.102 1.00 0.00 H new ATOM 0 H3' DC B 24 3.422 7.524 -3.468 1.00 0.00 H new ATOM 0 H2' DC B 24 3.259 5.177 -3.812 1.00 0.00 H new ATOM 0 H2'' DC B 24 4.954 4.946 -3.429 1.00 0.00 H new ATOM 0 HO3' DC B 24 5.290 7.179 -4.646 1.00 0.00 H new ATOM 0 H1' DC B 24 4.448 4.385 -1.255 1.00 0.00 H new ATOM 0 H41 DC B 24 -1.649 2.159 -1.032 1.00 0.00 H new ATOM 0 H42 DC B 24 -0.597 0.765 -1.303 1.00 0.00 H new ATOM 0 H5 DC B 24 -0.886 4.390 -1.094 1.00 0.00 H new ATOM 0 H6 DC B 24 1.103 5.829 -1.266 1.00 0.00 H new TER 770 DC B 24 CONECT 167 190 CONECT 189 190 CONECT 190 167 189 191 192 CONECT 191 190 CONECT 192 190 193 CONECT 193 192 194 213 214 CONECT 194 193 195 196 215 CONECT 195 194 199 CONECT 196 194 197 198 216 CONECT 197 196 227 CONECT 198 196 199 217 218 CONECT 199 195 198 200 219 CONECT 200 199 201 203 CONECT 201 200 202 205 CONECT 202 201 209 CONECT 203 200 204 220 CONECT 204 203 205 CONECT 205 201 204 206 CONECT 206 205 207 208 CONECT 207 206 CONECT 208 206 209 221 CONECT 209 202 208 210 CONECT 210 209 211 222 CONECT 211 210 212 223 597 CONECT 212 211 224 225 226 CONECT 213 193 CONECT 214 193 CONECT 215 194 CONECT 216 196 CONECT 217 198 CONECT 218 198 CONECT 219 199 CONECT 220 203 CONECT 221 208 CONECT 222 210 CONECT 223 211 CONECT 224 212 CONECT 225 212 CONECT 226 212 CONECT 227 197 CONECT 552 575 CONECT 574 575 CONECT 575 552 574 576 577 CONECT 576 575 CONECT 577 575 578 CONECT 578 577 579 598 599 CONECT 579 578 580 581 600 CONECT 580 579 584 CONECT 581 579 582 583 601 CONECT 582 581 612 CONECT 583 581 584 602 603 CONECT 584 580 583 585 604 CONECT 585 584 586 588 CONECT 586 585 587 590 CONECT 587 586 594 CONECT 588 585 589 605 CONECT 589 588 590 CONECT 590 586 589 591 CONECT 591 590 592 593 CONECT 592 591 CONECT 593 591 594 606 CONECT 594 587 593 595 CONECT 595 594 596 607 CONECT 596 595 597 608 CONECT 597 211 596 609 610 CONECT 597 611 CONECT 598 578 CONECT 599 578 CONECT 600 579 CONECT 601 581 CONECT 602 583 CONECT 603 583 CONECT 604 584 CONECT 605 588 CONECT 606 593 CONECT 607 595 CONECT 608 596 CONECT 609 597 CONECT 610 597 CONECT 611 597 CONECT 612 582 END