HEADER RNA 27-MAY-97 1AKX TITLE HIV-2 TRANS ACTIVATING REGION RNA COMPLEX WITH ARGININAMIDE, TITLE 2 NMR, MINIMIZED AVERAGE STRUCTURE COMPND MOL_ID: 1; COMPND 2 MOLECULE: TAR RNA; COMPND 3 CHAIN: A; COMPND 4 SYNONYM: TAR; COMPND 5 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 SYNTHETIC: YES KEYWDS TRANSCRIPTIONAL ACTIVATION, NMR, COMPLEX (RNA/LIGAND), KEYWDS 2 PROTEIN-RNA INTERACTIONS EXPDTA SOLUTION NMR AUTHOR A.S.BRODSKY,J.R.WILLIAMSON REVDAT 2 24-FEB-09 1AKX 1 VERSN REVDAT 1 19-NOV-97 1AKX 0 JRNL AUTH A.S.BRODSKY,J.R.WILLIAMSON JRNL TITL SOLUTION STRUCTURE OF THE HIV-2 TAR-ARGININAMIDE JRNL TITL 2 COMPLEX. JRNL REF J.MOL.BIOL. V. 267 624 1997 JRNL REFN ISSN 0022-2836 JRNL PMID 9126842 JRNL DOI 10.1006/JMBI.1996.0879 REMARK 1 REMARK 1 REFERENCE 1 REMARK 1 AUTH A.GELBIN,B.SCHNEIDER,L.CLOWNY,S.-H.HSIEH,W.K.OLSEN, REMARK 1 AUTH 2 H.M.BERMAN REMARK 1 TITL GEOMETRIC PARAMETERS IN NUCLEIC ACIDS: SUGAR AND REMARK 1 TITL 2 PHOSPHATE CONSTITUENTS REMARK 1 REF J.AM.CHEM.SOC. V. 118 519 1996 REMARK 1 REFN ISSN 0002-7863 REMARK 1 REFERENCE 2 REMARK 1 AUTH F.ABOUL-ELA,J.KARN,G.VARANI REMARK 1 TITL THE STRUCTURE OF THE HUMAN IMMUNODEFICIENCY VIRUS REMARK 1 TITL 2 TYPE-1 TAR RNA REVEALS PRINCIPLES OF RNA REMARK 1 TITL 3 RECOGNITION BY TAT PROTEIN REMARK 1 REF J.MOL.BIOL. V. 253 313 1995 REMARK 1 REFN ISSN 0022-2836 REMARK 1 REFERENCE 3 REMARK 1 AUTH J.D.PUGLISI,L.CHEN,A.D.FRANKEL,J.R.WILLIAMSON REMARK 1 TITL ROLE OF RNA STRUCTURE IN ARGININE RECOGNITION OF REMARK 1 TITL 2 TAR RNA REMARK 1 REF PROC.NATL.ACAD.SCI.USA V. 90 3680 1993 REMARK 1 REFN ISSN 0027-8424 REMARK 1 REFERENCE 4 REMARK 1 AUTH J.D.PUGLISI,R.TAN,B.J.CALNAN,A.D.FRANKEL, REMARK 1 AUTH 2 J.R.WILLIAMSON REMARK 1 TITL CONFORMATION OF THE TAR RNA-ARGININE COMPLEX BY REMARK 1 TITL 2 NMR SPECTROSCOPY REMARK 1 REF SCIENCE V. 257 76 1992 REMARK 1 REFN ISSN 0036-8075 REMARK 2 REMARK 2 RESOLUTION. NOT APPLICABLE. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : X-PLOR 3.1 REMARK 3 AUTHORS : BRUNGER REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: NULL REMARK 4 REMARK 4 1AKX COMPLIES WITH FORMAT V. 3.15, 01-DEC-08 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY BNL. REMARK 210 REMARK 210 EXPERIMENTAL DETAILS REMARK 210 EXPERIMENT TYPE : NMR REMARK 210 TEMPERATURE (KELVIN) : 298 REMARK 210 PH : 6.4 REMARK 210 IONIC STRENGTH : NULL REMARK 210 PRESSURE : NULL REMARK 210 SAMPLE CONTENTS : NULL REMARK 210 REMARK 210 NMR EXPERIMENTS CONDUCTED : SEE PAPER REMARK 210 SPECTROMETER FIELD STRENGTH : 500 MHZ, 591 MHZ, 750 MHZ REMARK 210 SPECTROMETER MODEL : VXR500, UNITY-PLUS, HOME-MADE REMARK 210 SPECTROMETER MANUFACTURER : VARIAN, HOME MADE REMARK 210 REMARK 210 STRUCTURE DETERMINATION. REMARK 210 SOFTWARE USED : X-PLOR 3.1 REMARK 210 METHOD USED : RANDOM COORDINATES AND REMARK 210 SIMULATED ANNEALING REMARK 210 REMARK 210 CONFORMERS, NUMBER CALCULATED : 20 REMARK 210 CONFORMERS, NUMBER SUBMITTED : 1 REMARK 210 CONFORMERS, SELECTION CRITERIA : LEAST RESTRAINTS AND LOWEST REMARK 210 ENERGY REMARK 210 REMARK 210 BEST REPRESENTATIVE CONFORMER IN THIS ENSEMBLE : NULL REMARK 210 REMARK 210 REMARK: NULL REMARK 215 REMARK 215 NMR STUDY REMARK 215 THE COORDINATES IN THIS ENTRY WERE GENERATED FROM SOLUTION REMARK 215 NMR DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE THAT REMARK 215 CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES ON REMARK 215 THESE RECORDS ARE MEANINGLESS. REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: PLANAR GROUPS REMARK 500 REMARK 500 PLANAR GROUPS IN THE FOLLOWING RESIDUES HAVE A TOTAL REMARK 500 RMS DISTANCE OF ALL ATOMS FROM THE BEST-FIT PLANE REMARK 500 BY MORE THAN AN EXPECTED VALUE OF 6*RMSD, WITH AN REMARK 500 RMSD 0.02 ANGSTROMS, OR AT LEAST ONE ATOM HAS REMARK 500 AN RMSD GREATER THAN THIS VALUE REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 M RES CSSEQI RMS TYPE REMARK 500 ARG A 47 0.21 SIDE_CHAIN REMARK 500 REMARK 500 REMARK: NULL REMARK 610 REMARK 610 MISSING HETEROATOM REMARK 610 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER; REMARK 610 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; REMARK 610 I=INSERTION CODE): REMARK 610 M RES C SSEQI REMARK 610 ARG A 47 REMARK 800 REMARK 800 SITE REMARK 800 SITE_IDENTIFIER: AC1 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ARG A 47 REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 1AJU RELATED DB: PDB REMARK 900 ENSEMBLE OF 20 STRUCTURES DBREF 1AKX A 16 46 PDB 1AKX 1AKX 16 46 SEQRES 1 A 30 G G C C A G A U U G A G C SEQRES 2 A 30 C U G G G A G C U C U C U SEQRES 3 A 30 G G C C HET ARG A 47 26 HETNAM ARG ARGININE FORMUL 2 ARG C6 H15 N4 O2 1+ SITE 1 AC1 4 A A 22 U A 23 G A 26 C A 37 CRYST1 1.000 1.000 1.000 90.00 90.00 90.00 P 1 1 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 1.000000 0.000000 0.000000 0.00000 SCALE2 0.000000 1.000000 0.000000 0.00000 SCALE3 0.000000 0.000000 1.000000 0.00000 ATOM 1 O5' G A 16 2.039 24.723 -5.470 1.00 0.00 O ATOM 2 C5' G A 16 2.191 23.531 -4.697 1.00 0.00 C ATOM 3 C4' G A 16 2.004 23.801 -3.222 1.00 0.00 C ATOM 4 O4' G A 16 0.625 24.187 -2.985 1.00 0.00 O ATOM 5 C3' G A 16 2.231 22.609 -2.306 1.00 0.00 C ATOM 6 O3' G A 16 3.607 22.475 -1.963 1.00 0.00 O ATOM 7 C2' G A 16 1.373 22.950 -1.093 1.00 0.00 C ATOM 8 O2' G A 16 2.019 23.860 -0.222 1.00 0.00 O ATOM 9 C1' G A 16 0.179 23.644 -1.753 1.00 0.00 C ATOM 10 N9 G A 16 -0.946 22.747 -2.014 1.00 0.00 N ATOM 11 C8 G A 16 -1.277 22.149 -3.207 1.00 0.00 C ATOM 12 N7 G A 16 -2.341 21.397 -3.130 1.00 0.00 N ATOM 13 C5 G A 16 -2.741 21.505 -1.805 1.00 0.00 C ATOM 14 C6 G A 16 -3.839 20.912 -1.120 1.00 0.00 C ATOM 15 O6 G A 16 -4.702 20.149 -1.571 1.00 0.00 O ATOM 16 N1 G A 16 -3.881 21.285 0.227 1.00 0.00 N ATOM 17 C2 G A 16 -2.970 22.128 0.829 1.00 0.00 C ATOM 18 N2 G A 16 -3.166 22.376 2.132 1.00 0.00 N ATOM 19 N3 G A 16 -1.944 22.686 0.201 1.00 0.00 N ATOM 20 C4 G A 16 -1.889 22.334 -1.103 1.00 0.00 C ATOM 21 H5' G A 16 3.188 23.118 -4.860 1.00 0.00 H ATOM 22 H5'' G A 16 1.453 22.795 -5.013 1.00 0.00 H ATOM 23 H4' G A 16 2.726 24.566 -2.933 1.00 0.00 H ATOM 24 H3' G A 16 1.941 21.671 -2.780 1.00 0.00 H ATOM 25 H2' G A 16 1.064 22.036 -0.582 1.00 0.00 H ATOM 26 HO2' G A 16 2.538 23.343 0.395 1.00 0.00 H ATOM 27 H1' G A 16 -0.190 24.479 -1.155 1.00 0.00 H ATOM 28 H8 G A 16 -0.711 22.286 -4.117 1.00 0.00 H ATOM 29 H1 G A 16 -4.627 20.912 0.796 1.00 0.00 H ATOM 30 H21 G A 16 -3.947 21.954 2.615 1.00 0.00 H ATOM 31 H22 G A 16 -2.534 22.985 2.631 1.00 0.00 H ATOM 32 HO5' G A 16 2.776 25.299 -5.254 1.00 0.00 H ATOM 33 P G A 17 4.130 21.140 -1.230 1.00 0.00 P ATOM 34 OP1 G A 17 5.601 21.271 -1.072 1.00 0.00 O ATOM 35 OP2 G A 17 3.570 19.964 -1.945 1.00 0.00 O ATOM 36 O5' G A 17 3.470 21.209 0.219 1.00 0.00 O ATOM 37 C5' G A 17 3.257 20.029 0.992 1.00 0.00 C ATOM 38 C4' G A 17 2.341 20.331 2.155 1.00 0.00 C ATOM 39 O4' G A 17 1.153 21.012 1.663 1.00 0.00 O ATOM 40 C3' G A 17 1.807 19.115 2.902 1.00 0.00 C ATOM 41 O3' G A 17 2.704 18.699 3.929 1.00 0.00 O ATOM 42 C2' G A 17 0.490 19.629 3.465 1.00 0.00 C ATOM 43 O2' G A 17 0.678 20.459 4.597 1.00 0.00 O ATOM 44 C1' G A 17 0.001 20.475 2.291 1.00 0.00 C ATOM 45 N9 G A 17 -0.761 19.714 1.301 1.00 0.00 N ATOM 46 C8 G A 17 -0.408 19.450 -0.002 1.00 0.00 C ATOM 47 N7 G A 17 -1.295 18.740 -0.644 1.00 0.00 N ATOM 48 C5 G A 17 -2.297 18.521 0.291 1.00 0.00 C ATOM 49 C6 G A 17 -3.526 17.812 0.178 1.00 0.00 C ATOM 50 O6 G A 17 -3.979 17.217 -0.807 1.00 0.00 O ATOM 51 N1 G A 17 -4.257 17.833 1.370 1.00 0.00 N ATOM 52 C2 G A 17 -3.842 18.464 2.525 1.00 0.00 C ATOM 53 N2 G A 17 -4.671 18.380 3.575 1.00 0.00 N ATOM 54 N3 G A 17 -2.700 19.128 2.641 1.00 0.00 N ATOM 55 C4 G A 17 -1.983 19.116 1.496 1.00 0.00 C ATOM 56 H5' G A 17 4.211 19.662 1.372 1.00 0.00 H ATOM 57 H5'' G A 17 2.801 19.257 0.372 1.00 0.00 H ATOM 58 H4' G A 17 2.910 20.919 2.877 1.00 0.00 H ATOM 59 H3' G A 17 1.678 18.258 2.242 1.00 0.00 H ATOM 60 H2' G A 17 -0.188 18.795 3.665 1.00 0.00 H ATOM 61 HO2' G A 17 0.147 20.096 5.307 1.00 0.00 H ATOM 62 H1' G A 17 -0.610 21.318 2.615 1.00 0.00 H ATOM 63 H8 G A 17 0.513 19.794 -0.449 1.00 0.00 H ATOM 64 H1 G A 17 -5.147 17.354 1.386 1.00 0.00 H ATOM 65 H21 G A 17 -5.542 17.876 3.492 1.00 0.00 H ATOM 66 H22 G A 17 -4.425 18.821 4.450 1.00 0.00 H ATOM 67 P C A 18 2.691 17.174 4.445 1.00 0.00 P ATOM 68 OP1 C A 18 3.708 17.037 5.519 1.00 0.00 O ATOM 69 OP2 C A 18 2.769 16.298 3.248 1.00 0.00 O ATOM 70 O5' C A 18 1.247 16.994 5.097 1.00 0.00 O ATOM 71 C5' C A 18 0.914 17.614 6.338 1.00 0.00 C ATOM 72 C4' C A 18 -0.479 17.210 6.767 1.00 0.00 C ATOM 73 O4' C A 18 -1.421 17.571 5.727 1.00 0.00 O ATOM 74 C3' C A 18 -0.697 15.720 6.971 1.00 0.00 C ATOM 75 O3' C A 18 -0.294 15.317 8.277 1.00 0.00 O ATOM 76 C2' C A 18 -2.203 15.568 6.766 1.00 0.00 C ATOM 77 O2' C A 18 -2.931 15.877 7.940 1.00 0.00 O ATOM 78 C1' C A 18 -2.487 16.634 5.701 1.00 0.00 C ATOM 79 N1 C A 18 -2.609 16.083 4.334 1.00 0.00 N ATOM 80 C2 C A 18 -3.843 15.552 3.927 1.00 0.00 C ATOM 81 O2 C A 18 -4.794 15.552 4.724 1.00 0.00 O ATOM 82 N3 C A 18 -3.964 15.050 2.673 1.00 0.00 N ATOM 83 C4 C A 18 -2.917 15.064 1.840 1.00 0.00 C ATOM 84 N4 C A 18 -3.086 14.562 0.615 1.00 0.00 N ATOM 85 C5 C A 18 -1.649 15.594 2.227 1.00 0.00 C ATOM 86 C6 C A 18 -1.540 16.088 3.470 1.00 0.00 C ATOM 87 H5' C A 18 0.956 18.698 6.231 1.00 0.00 H ATOM 88 H5'' C A 18 1.623 17.307 7.106 1.00 0.00 H ATOM 89 H4' C A 18 -0.681 17.692 7.724 1.00 0.00 H ATOM 90 H3' C A 18 -0.112 15.124 6.272 1.00 0.00 H ATOM 91 H2' C A 18 -2.430 14.568 6.390 1.00 0.00 H ATOM 92 HO2' C A 18 -3.477 15.118 8.145 1.00 0.00 H ATOM 93 H1' C A 18 -3.399 17.192 5.918 1.00 0.00 H ATOM 94 H41 C A 18 -3.985 14.190 0.342 1.00 0.00 H ATOM 95 H42 C A 18 -2.317 14.556 -0.039 1.00 0.00 H ATOM 96 H5 C A 18 -0.802 15.597 1.541 1.00 0.00 H ATOM 97 H6 C A 18 -0.586 16.498 3.797 1.00 0.00 H ATOM 98 P C A 19 -0.290 13.758 8.677 1.00 0.00 P ATOM 99 OP1 C A 19 0.042 13.672 10.121 1.00 0.00 O ATOM 100 OP2 C A 19 0.544 13.025 7.689 1.00 0.00 O ATOM 101 O5' C A 19 -1.808 13.305 8.492 1.00 0.00 O ATOM 102 C5' C A 19 -2.138 12.055 7.892 1.00 0.00 C ATOM 103 C4' C A 19 -3.639 11.893 7.826 1.00 0.00 C ATOM 104 O4' C A 19 -4.175 12.814 6.835 1.00 0.00 O ATOM 105 C3' C A 19 -4.127 10.521 7.381 1.00 0.00 C ATOM 106 O3' C A 19 -4.250 9.630 8.485 1.00 0.00 O ATOM 107 C2' C A 19 -5.476 10.839 6.753 1.00 0.00 C ATOM 108 O2' C A 19 -6.480 11.065 7.726 1.00 0.00 O ATOM 109 C1' C A 19 -5.150 12.153 6.044 1.00 0.00 C ATOM 110 N1 C A 19 -4.622 11.968 4.674 1.00 0.00 N ATOM 111 C2 C A 19 -5.477 11.460 3.682 1.00 0.00 C ATOM 112 O2 C A 19 -6.650 11.183 3.980 1.00 0.00 O ATOM 113 N3 C A 19 -5.001 11.285 2.425 1.00 0.00 N ATOM 114 C4 C A 19 -3.731 11.593 2.138 1.00 0.00 C ATOM 115 N4 C A 19 -3.310 11.404 0.886 1.00 0.00 N ATOM 116 C5 C A 19 -2.837 12.111 3.124 1.00 0.00 C ATOM 117 C6 C A 19 -3.319 12.281 4.365 1.00 0.00 C ATOM 118 H5' C A 19 -1.715 11.241 8.481 1.00 0.00 H ATOM 119 H5'' C A 19 -1.732 12.010 6.883 1.00 0.00 H ATOM 120 H4' C A 19 -4.033 12.057 8.830 1.00 0.00 H ATOM 121 H3' C A 19 -3.436 10.052 6.682 1.00 0.00 H ATOM 122 H2' C A 19 -5.754 10.061 6.039 1.00 0.00 H ATOM 123 HO2' C A 19 -7.281 10.649 7.409 1.00 0.00 H ATOM 124 H1' C A 19 -6.016 12.814 5.986 1.00 0.00 H ATOM 125 H41 C A 19 -3.943 11.037 0.190 1.00 0.00 H ATOM 126 H42 C A 19 -2.357 11.626 0.635 1.00 0.00 H ATOM 127 H5 C A 19 -1.804 12.356 2.879 1.00 0.00 H ATOM 128 H6 C A 19 -2.662 12.678 5.138 1.00 0.00 H ATOM 129 P A A 20 -4.067 8.046 8.267 1.00 0.00 P ATOM 130 OP1 A A 20 -4.293 7.368 9.569 1.00 0.00 O ATOM 131 OP2 A A 20 -2.784 7.840 7.548 1.00 0.00 O ATOM 132 O5' A A 20 -5.255 7.650 7.282 1.00 0.00 O ATOM 133 C5' A A 20 -6.603 7.594 7.742 1.00 0.00 C ATOM 134 C4' A A 20 -7.531 7.242 6.602 1.00 0.00 C ATOM 135 O4' A A 20 -7.393 8.232 5.551 1.00 0.00 O ATOM 136 C3' A A 20 -7.247 5.924 5.905 1.00 0.00 C ATOM 137 O3' A A 20 -7.824 4.825 6.604 1.00 0.00 O ATOM 138 C2' A A 20 -7.895 6.135 4.543 1.00 0.00 C ATOM 139 O2' A A 20 -9.301 5.973 4.589 1.00 0.00 O ATOM 140 C1' A A 20 -7.563 7.608 4.287 1.00 0.00 C ATOM 141 N9 A A 20 -6.344 7.794 3.495 1.00 0.00 N ATOM 142 C8 A A 20 -5.128 8.283 3.910 1.00 0.00 C ATOM 143 N7 A A 20 -4.224 8.330 2.960 1.00 0.00 N ATOM 144 C5 A A 20 -4.887 7.838 1.846 1.00 0.00 C ATOM 145 C6 A A 20 -4.481 7.628 0.512 1.00 0.00 C ATOM 146 N6 A A 20 -3.256 7.903 0.060 1.00 0.00 N ATOM 147 N1 A A 20 -5.392 7.120 -0.355 1.00 0.00 N ATOM 148 C2 A A 20 -6.626 6.842 0.096 1.00 0.00 C ATOM 149 N3 A A 20 -7.125 6.995 1.324 1.00 0.00 N ATOM 150 C4 A A 20 -6.194 7.503 2.161 1.00 0.00 C ATOM 151 H5' A A 20 -6.892 8.561 8.154 1.00 0.00 H ATOM 152 H5'' A A 20 -6.696 6.836 8.520 1.00 0.00 H ATOM 153 H4' A A 20 -8.541 7.175 7.007 1.00 0.00 H ATOM 154 H3' A A 20 -6.179 5.720 5.838 1.00 0.00 H ATOM 155 H2' A A 20 -7.425 5.490 3.799 1.00 0.00 H ATOM 156 HO2' A A 20 -9.546 5.407 3.858 1.00 0.00 H ATOM 157 H1' A A 20 -8.376 8.130 3.781 1.00 0.00 H ATOM 158 H8 A A 20 -4.932 8.597 4.924 1.00 0.00 H ATOM 159 H61 A A 20 -3.024 7.731 -0.908 1.00 0.00 H ATOM 160 H62 A A 20 -2.560 8.282 0.686 1.00 0.00 H ATOM 161 H2 A A 20 -7.316 6.436 -0.643 1.00 0.00 H ATOM 162 P G A 21 -7.290 3.330 6.333 1.00 0.00 P ATOM 163 OP1 G A 21 -8.065 2.396 7.189 1.00 0.00 O ATOM 164 OP2 G A 21 -5.809 3.359 6.438 1.00 0.00 O ATOM 165 O5' G A 21 -7.671 3.050 4.809 1.00 0.00 O ATOM 166 C5' G A 21 -9.013 2.756 4.428 1.00 0.00 C ATOM 167 C4' G A 21 -9.152 2.788 2.922 1.00 0.00 C ATOM 168 O4' G A 21 -8.464 3.951 2.393 1.00 0.00 O ATOM 169 C3' G A 21 -8.521 1.625 2.179 1.00 0.00 C ATOM 170 O3' G A 21 -9.373 0.482 2.178 1.00 0.00 O ATOM 171 C2' G A 21 -8.337 2.206 0.783 1.00 0.00 C ATOM 172 O2' G A 21 -9.550 2.242 0.054 1.00 0.00 O ATOM 173 C1' G A 21 -7.908 3.634 1.124 1.00 0.00 C ATOM 174 N9 G A 21 -6.457 3.799 1.186 1.00 0.00 N ATOM 175 C8 G A 21 -5.675 3.917 2.309 1.00 0.00 C ATOM 176 N7 G A 21 -4.405 4.057 2.042 1.00 0.00 N ATOM 177 C5 G A 21 -4.343 4.026 0.655 1.00 0.00 C ATOM 178 C6 G A 21 -3.228 4.130 -0.225 1.00 0.00 C ATOM 179 O6 G A 21 -2.034 4.278 0.063 1.00 0.00 O ATOM 180 N1 G A 21 -3.610 4.046 -1.568 1.00 0.00 N ATOM 181 C2 G A 21 -4.910 3.882 -1.997 1.00 0.00 C ATOM 182 N2 G A 21 -5.092 3.818 -3.322 1.00 0.00 N ATOM 183 N3 G A 21 -5.955 3.787 -1.188 1.00 0.00 N ATOM 184 C4 G A 21 -5.602 3.866 0.114 1.00 0.00 C ATOM 185 H5' G A 21 -9.690 3.491 4.865 1.00 0.00 H ATOM 186 H5'' G A 21 -9.289 1.765 4.786 1.00 0.00 H ATOM 187 H4' G A 21 -10.217 2.770 2.689 1.00 0.00 H ATOM 188 H3' G A 21 -7.582 1.313 2.636 1.00 0.00 H ATOM 189 H2' G A 21 -7.545 1.672 0.252 1.00 0.00 H ATOM 190 HO2' G A 21 -9.871 1.343 -0.008 1.00 0.00 H ATOM 191 H1' G A 21 -8.301 4.363 0.413 1.00 0.00 H ATOM 192 H8 G A 21 -6.070 3.881 3.312 1.00 0.00 H ATOM 193 H1 G A 21 -2.885 4.108 -2.269 1.00 0.00 H ATOM 194 H21 G A 21 -4.300 3.889 -3.945 1.00 0.00 H ATOM 195 H22 G A 21 -6.021 3.697 -3.699 1.00 0.00 H ATOM 196 P A A 22 -8.950 -0.842 1.366 1.00 0.00 P ATOM 197 OP1 A A 22 -9.822 -1.947 1.839 1.00 0.00 O ATOM 198 OP2 A A 22 -7.474 -0.989 1.444 1.00 0.00 O ATOM 199 O5' A A 22 -9.343 -0.509 -0.143 1.00 0.00 O ATOM 200 C5' A A 22 -9.006 -1.396 -1.208 1.00 0.00 C ATOM 201 C4' A A 22 -8.455 -0.618 -2.385 1.00 0.00 C ATOM 202 O4' A A 22 -7.581 0.426 -1.891 1.00 0.00 O ATOM 203 C3' A A 22 -7.581 -1.414 -3.342 1.00 0.00 C ATOM 204 O3' A A 22 -8.364 -2.083 -4.327 1.00 0.00 O ATOM 205 C2' A A 22 -6.695 -0.342 -3.973 1.00 0.00 C ATOM 206 O2' A A 22 -7.331 0.297 -5.063 1.00 0.00 O ATOM 207 C1' A A 22 -6.538 0.662 -2.822 1.00 0.00 C ATOM 208 N9 A A 22 -5.252 0.574 -2.122 1.00 0.00 N ATOM 209 C8 A A 22 -5.029 0.296 -0.792 1.00 0.00 C ATOM 210 N7 A A 22 -3.763 0.309 -0.453 1.00 0.00 N ATOM 211 C5 A A 22 -3.105 0.608 -1.636 1.00 0.00 C ATOM 212 C6 A A 22 -1.739 0.768 -1.949 1.00 0.00 C ATOM 213 N6 A A 22 -0.758 0.649 -1.053 1.00 0.00 N ATOM 214 N1 A A 22 -1.413 1.061 -3.232 1.00 0.00 N ATOM 215 C2 A A 22 -2.400 1.185 -4.134 1.00 0.00 C ATOM 216 N3 A A 22 -3.718 1.062 -3.960 1.00 0.00 N ATOM 217 C4 A A 22 -4.009 0.769 -2.675 1.00 0.00 C ATOM 218 H5' A A 22 -9.896 -1.942 -1.525 1.00 0.00 H ATOM 219 H5'' A A 22 -8.255 -2.110 -0.873 1.00 0.00 H ATOM 220 H4' A A 22 -9.301 -0.244 -2.962 1.00 0.00 H ATOM 221 H3' A A 22 -7.012 -2.186 -2.828 1.00 0.00 H ATOM 222 H2' A A 22 -5.731 -0.772 -4.253 1.00 0.00 H ATOM 223 HO2' A A 22 -8.276 0.222 -4.926 1.00 0.00 H ATOM 224 H1' A A 22 -6.657 1.690 -3.167 1.00 0.00 H ATOM 225 H8 A A 22 -5.822 0.076 -0.094 1.00 0.00 H ATOM 226 H61 A A 22 0.202 0.790 -1.335 1.00 0.00 H ATOM 227 H62 A A 22 -0.975 0.432 -0.091 1.00 0.00 H ATOM 228 H2 A A 22 -2.080 1.416 -5.149 1.00 0.00 H ATOM 229 P U A 23 -9.302 -3.325 -3.920 1.00 0.00 P ATOM 230 OP1 U A 23 -10.703 -2.841 -3.833 1.00 0.00 O ATOM 231 OP2 U A 23 -8.683 -3.994 -2.746 1.00 0.00 O ATOM 232 O5' U A 23 -9.191 -4.312 -5.166 1.00 0.00 O ATOM 233 C5' U A 23 -7.950 -4.923 -5.512 1.00 0.00 C ATOM 234 C4' U A 23 -7.262 -4.131 -6.602 1.00 0.00 C ATOM 235 O4' U A 23 -5.870 -3.935 -6.224 1.00 0.00 O ATOM 236 C3' U A 23 -7.218 -4.814 -7.967 1.00 0.00 C ATOM 237 O3' U A 23 -7.284 -3.860 -9.025 1.00 0.00 O ATOM 238 C2' U A 23 -5.879 -5.543 -7.945 1.00 0.00 C ATOM 239 O2' U A 23 -5.349 -5.722 -9.244 1.00 0.00 O ATOM 240 C1' U A 23 -5.022 -4.544 -7.179 1.00 0.00 C ATOM 241 N1 U A 23 -3.879 -5.160 -6.474 1.00 0.00 N ATOM 242 C2 U A 23 -2.745 -5.458 -7.218 1.00 0.00 C ATOM 243 O2 U A 23 -2.659 -5.236 -8.414 1.00 0.00 O ATOM 244 N3 U A 23 -1.714 -6.028 -6.507 1.00 0.00 N ATOM 245 C4 U A 23 -1.698 -6.321 -5.156 1.00 0.00 C ATOM 246 O4 U A 23 -0.689 -6.823 -4.658 1.00 0.00 O ATOM 247 C5 U A 23 -2.903 -5.985 -4.457 1.00 0.00 C ATOM 248 C6 U A 23 -3.930 -5.432 -5.118 1.00 0.00 C ATOM 249 H5' U A 23 -8.129 -5.940 -5.866 1.00 0.00 H ATOM 250 H5'' U A 23 -7.300 -4.963 -4.639 1.00 0.00 H ATOM 251 H4' U A 23 -7.815 -3.200 -6.732 1.00 0.00 H ATOM 252 H3' U A 23 -8.061 -5.489 -8.112 1.00 0.00 H ATOM 253 H2' U A 23 -5.969 -6.482 -7.399 1.00 0.00 H ATOM 254 HO2' U A 23 -4.918 -6.577 -9.260 1.00 0.00 H ATOM 255 H1' U A 23 -4.641 -3.751 -7.822 1.00 0.00 H ATOM 256 H3 U A 23 -0.881 -6.260 -7.028 1.00 0.00 H ATOM 257 H5 U A 23 -2.984 -6.176 -3.385 1.00 0.00 H ATOM 258 H6 U A 23 -4.840 -5.195 -4.567 1.00 0.00 H ATOM 259 P U A 25 -8.698 -3.221 -9.460 1.00 0.00 P ATOM 260 OP1 U A 25 -9.763 -4.189 -9.090 1.00 0.00 O ATOM 261 OP2 U A 25 -8.586 -2.759 -10.866 1.00 0.00 O ATOM 262 O5' U A 25 -8.848 -1.938 -8.524 1.00 0.00 O ATOM 263 C5' U A 25 -10.052 -1.171 -8.504 1.00 0.00 C ATOM 264 C4' U A 25 -9.742 0.287 -8.759 1.00 0.00 C ATOM 265 O4' U A 25 -10.931 1.080 -8.482 1.00 0.00 O ATOM 266 C3' U A 25 -8.638 0.890 -7.884 1.00 0.00 C ATOM 267 O3' U A 25 -7.818 1.779 -8.636 1.00 0.00 O ATOM 268 C2' U A 25 -9.414 1.629 -6.804 1.00 0.00 C ATOM 269 O2' U A 25 -8.686 2.718 -6.271 1.00 0.00 O ATOM 270 C1' U A 25 -10.574 2.143 -7.633 1.00 0.00 C ATOM 271 N1 U A 25 -11.751 2.553 -6.846 1.00 0.00 N ATOM 272 C2 U A 25 -12.226 3.850 -7.012 1.00 0.00 C ATOM 273 O2 U A 25 -11.716 4.654 -7.774 1.00 0.00 O ATOM 274 N3 U A 25 -13.326 4.167 -6.247 1.00 0.00 N ATOM 275 C4 U A 25 -13.984 3.341 -5.356 1.00 0.00 C ATOM 276 O4 U A 25 -14.962 3.771 -4.742 1.00 0.00 O ATOM 277 C5 U A 25 -13.433 2.022 -5.243 1.00 0.00 C ATOM 278 C6 U A 25 -12.363 1.677 -5.971 1.00 0.00 C ATOM 279 H5' U A 25 -10.535 -1.271 -7.532 1.00 0.00 H ATOM 280 H5'' U A 25 -10.732 -1.528 -9.277 1.00 0.00 H ATOM 281 H4' U A 25 -9.401 0.376 -9.788 1.00 0.00 H ATOM 282 H3' U A 25 -7.975 0.126 -7.481 1.00 0.00 H ATOM 283 H2' U A 25 -9.755 0.934 -6.036 1.00 0.00 H ATOM 284 HO2' U A 25 -8.191 2.390 -5.521 1.00 0.00 H ATOM 285 H1' U A 25 -10.279 2.968 -8.276 1.00 0.00 H ATOM 286 H3 U A 25 -13.690 5.103 -6.348 1.00 0.00 H ATOM 287 H5 U A 25 -13.885 1.300 -4.563 1.00 0.00 H ATOM 288 H6 U A 25 -11.962 0.669 -5.870 1.00 0.00 H ATOM 289 P G A 26 -6.346 1.324 -9.088 1.00 0.00 P ATOM 290 OP1 G A 26 -5.599 0.896 -7.878 1.00 0.00 O ATOM 291 OP2 G A 26 -5.794 2.402 -9.947 1.00 0.00 O ATOM 292 O5' G A 26 -6.606 0.045 -10.007 1.00 0.00 O ATOM 293 C5' G A 26 -5.754 -1.098 -9.952 1.00 0.00 C ATOM 294 C4' G A 26 -4.443 -0.811 -10.649 1.00 0.00 C ATOM 295 O4' G A 26 -3.706 0.195 -9.901 1.00 0.00 O ATOM 296 C3' G A 26 -3.491 -1.992 -10.759 1.00 0.00 C ATOM 297 O3' G A 26 -3.759 -2.759 -11.931 1.00 0.00 O ATOM 298 C2' G A 26 -2.126 -1.317 -10.807 1.00 0.00 C ATOM 299 O2' G A 26 -1.838 -0.784 -12.087 1.00 0.00 O ATOM 300 C1' G A 26 -2.342 -0.175 -9.817 1.00 0.00 C ATOM 301 N9 G A 26 -2.044 -0.533 -8.431 1.00 0.00 N ATOM 302 C8 G A 26 -2.944 -0.871 -7.449 1.00 0.00 C ATOM 303 N7 G A 26 -2.383 -1.139 -6.305 1.00 0.00 N ATOM 304 C5 G A 26 -1.027 -0.970 -6.540 1.00 0.00 C ATOM 305 C6 G A 26 0.085 -1.122 -5.667 1.00 0.00 C ATOM 306 O6 G A 26 0.083 -1.446 -4.474 1.00 0.00 O ATOM 307 N1 G A 26 1.298 -0.856 -6.310 1.00 0.00 N ATOM 308 C2 G A 26 1.412 -0.487 -7.635 1.00 0.00 C ATOM 309 N2 G A 26 2.657 -0.274 -8.082 1.00 0.00 N ATOM 310 N3 G A 26 0.381 -0.341 -8.458 1.00 0.00 N ATOM 311 C4 G A 26 -0.800 -0.596 -7.850 1.00 0.00 C ATOM 312 H5' G A 26 -6.241 -1.942 -10.442 1.00 0.00 H ATOM 313 H5'' G A 26 -5.554 -1.361 -8.914 1.00 0.00 H ATOM 314 H4' G A 26 -4.679 -0.506 -11.668 1.00 0.00 H ATOM 315 H3' G A 26 -3.594 -2.676 -9.917 1.00 0.00 H ATOM 316 H2' G A 26 -1.352 -2.000 -10.455 1.00 0.00 H ATOM 317 HO2' G A 26 -1.069 -1.246 -12.421 1.00 0.00 H ATOM 318 H1' G A 26 -1.754 0.706 -10.073 1.00 0.00 H ATOM 319 H8 G A 26 -4.010 -0.913 -7.610 1.00 0.00 H ATOM 320 H1 G A 26 2.146 -0.938 -5.769 1.00 0.00 H ATOM 321 H21 G A 26 3.444 -0.385 -7.458 1.00 0.00 H ATOM 322 H22 G A 26 2.809 -0.002 -9.043 1.00 0.00 H ATOM 323 P A A 27 -3.058 -4.191 -12.140 1.00 0.00 P ATOM 324 OP1 A A 27 -3.299 -4.600 -13.547 1.00 0.00 O ATOM 325 OP2 A A 27 -3.484 -5.085 -11.035 1.00 0.00 O ATOM 326 O5' A A 27 -1.501 -3.889 -11.974 1.00 0.00 O ATOM 327 C5' A A 27 -0.620 -4.847 -11.393 1.00 0.00 C ATOM 328 C4' A A 27 0.785 -4.293 -11.346 1.00 0.00 C ATOM 329 O4' A A 27 0.820 -3.148 -10.450 1.00 0.00 O ATOM 330 C3' A A 27 1.844 -5.243 -10.802 1.00 0.00 C ATOM 331 O3' A A 27 2.378 -6.066 -11.836 1.00 0.00 O ATOM 332 C2' A A 27 2.882 -4.286 -10.232 1.00 0.00 C ATOM 333 O2' A A 27 3.685 -3.703 -11.243 1.00 0.00 O ATOM 334 C1' A A 27 1.971 -3.220 -9.626 1.00 0.00 C ATOM 335 N9 A A 27 1.544 -3.520 -8.255 1.00 0.00 N ATOM 336 C8 A A 27 0.279 -3.834 -7.820 1.00 0.00 C ATOM 337 N7 A A 27 0.201 -4.056 -6.531 1.00 0.00 N ATOM 338 C5 A A 27 1.500 -3.877 -6.082 1.00 0.00 C ATOM 339 C6 A A 27 2.083 -3.968 -4.802 1.00 0.00 C ATOM 340 N6 A A 27 1.398 -4.278 -3.699 1.00 0.00 N ATOM 341 N1 A A 27 3.413 -3.726 -4.692 1.00 0.00 N ATOM 342 C2 A A 27 4.104 -3.414 -5.801 1.00 0.00 C ATOM 343 N3 A A 27 3.668 -3.299 -7.060 1.00 0.00 N ATOM 344 C4 A A 27 2.342 -3.545 -7.133 1.00 0.00 C ATOM 345 H5' A A 27 -0.626 -5.761 -11.988 1.00 0.00 H ATOM 346 H5'' A A 27 -0.944 -5.081 -10.380 1.00 0.00 H ATOM 347 H4' A A 27 1.076 -4.052 -12.369 1.00 0.00 H ATOM 348 H3' A A 27 1.436 -5.918 -10.051 1.00 0.00 H ATOM 349 H2' A A 27 3.474 -4.783 -9.462 1.00 0.00 H ATOM 350 HO2' A A 27 4.597 -3.911 -11.036 1.00 0.00 H ATOM 351 H1' A A 27 2.432 -2.231 -9.630 1.00 0.00 H ATOM 352 H8 A A 27 -0.575 -3.888 -8.478 1.00 0.00 H ATOM 353 H61 A A 27 1.871 -4.328 -2.808 1.00 0.00 H ATOM 354 H62 A A 27 0.406 -4.462 -3.755 1.00 0.00 H ATOM 355 H2 A A 27 5.168 -3.227 -5.653 1.00 0.00 H ATOM 356 P G A 28 2.815 -7.585 -11.526 1.00 0.00 P ATOM 357 OP1 G A 28 3.064 -8.249 -12.831 1.00 0.00 O ATOM 358 OP2 G A 28 1.833 -8.175 -10.580 1.00 0.00 O ATOM 359 O5' G A 28 4.211 -7.440 -10.770 1.00 0.00 O ATOM 360 C5' G A 28 5.345 -6.874 -11.423 1.00 0.00 C ATOM 361 C4' G A 28 6.356 -6.406 -10.403 1.00 0.00 C ATOM 362 O4' G A 28 5.706 -5.510 -9.464 1.00 0.00 O ATOM 363 C3' G A 28 6.960 -7.495 -9.532 1.00 0.00 C ATOM 364 O3' G A 28 8.073 -8.110 -10.175 1.00 0.00 O ATOM 365 C2' G A 28 7.376 -6.725 -8.284 1.00 0.00 C ATOM 366 O2' G A 28 8.596 -6.030 -8.465 1.00 0.00 O ATOM 367 C1' G A 28 6.231 -5.718 -8.162 1.00 0.00 C ATOM 368 N9 G A 28 5.150 -6.168 -7.283 1.00 0.00 N ATOM 369 C8 G A 28 3.894 -6.589 -7.650 1.00 0.00 C ATOM 370 N7 G A 28 3.144 -6.925 -6.637 1.00 0.00 N ATOM 371 C5 G A 28 3.953 -6.716 -5.530 1.00 0.00 C ATOM 372 C6 G A 28 3.688 -6.905 -4.145 1.00 0.00 C ATOM 373 O6 G A 28 2.647 -7.309 -3.613 1.00 0.00 O ATOM 374 N1 G A 28 4.788 -6.572 -3.348 1.00 0.00 N ATOM 375 C2 G A 28 5.993 -6.114 -3.840 1.00 0.00 C ATOM 376 N2 G A 28 6.940 -5.848 -2.929 1.00 0.00 N ATOM 377 N3 G A 28 6.251 -5.931 -5.129 1.00 0.00 N ATOM 378 C4 G A 28 5.195 -6.250 -5.911 1.00 0.00 C ATOM 379 H5' G A 28 5.033 -6.025 -12.033 1.00 0.00 H ATOM 380 H5'' G A 28 5.810 -7.619 -12.067 1.00 0.00 H ATOM 381 H4' G A 28 7.180 -5.943 -10.946 1.00 0.00 H ATOM 382 H3' G A 28 6.246 -8.291 -9.321 1.00 0.00 H ATOM 383 H2' G A 28 7.402 -7.393 -7.423 1.00 0.00 H ATOM 384 HO2' G A 28 8.867 -6.163 -9.373 1.00 0.00 H ATOM 385 H1' G A 28 6.576 -4.748 -7.802 1.00 0.00 H ATOM 386 H8 G A 28 3.561 -6.639 -8.675 1.00 0.00 H ATOM 387 H1 G A 28 4.694 -6.673 -2.348 1.00 0.00 H ATOM 388 H21 G A 28 6.749 -5.988 -1.947 1.00 0.00 H ATOM 389 H22 G A 28 7.845 -5.511 -3.224 1.00 0.00 H ATOM 390 P C A 29 8.419 -9.657 -9.896 1.00 0.00 P ATOM 391 OP1 C A 29 9.555 -10.043 -10.770 1.00 0.00 O ATOM 392 OP2 C A 29 7.148 -10.422 -9.970 1.00 0.00 O ATOM 393 O5' C A 29 8.921 -9.676 -8.384 1.00 0.00 O ATOM 394 C5' C A 29 10.144 -9.048 -8.010 1.00 0.00 C ATOM 395 C4' C A 29 10.195 -8.843 -6.512 1.00 0.00 C ATOM 396 O4' C A 29 9.009 -8.130 -6.083 1.00 0.00 O ATOM 397 C3' C A 29 10.191 -10.110 -5.675 1.00 0.00 C ATOM 398 O3' C A 29 11.507 -10.643 -5.553 1.00 0.00 O ATOM 399 C2' C A 29 9.643 -9.622 -4.336 1.00 0.00 C ATOM 400 O2' C A 29 10.641 -9.000 -3.547 1.00 0.00 O ATOM 401 C1' C A 29 8.628 -8.565 -4.786 1.00 0.00 C ATOM 402 N1 C A 29 7.233 -9.058 -4.831 1.00 0.00 N ATOM 403 C2 C A 29 6.515 -9.166 -3.630 1.00 0.00 C ATOM 404 O2 C A 29 7.071 -8.858 -2.563 1.00 0.00 O ATOM 405 N3 C A 29 5.232 -9.604 -3.663 1.00 0.00 N ATOM 406 C4 C A 29 4.664 -9.928 -4.830 1.00 0.00 C ATOM 407 N4 C A 29 3.396 -10.348 -4.816 1.00 0.00 N ATOM 408 C5 C A 29 5.370 -9.836 -6.067 1.00 0.00 C ATOM 409 C6 C A 29 6.639 -9.402 -6.022 1.00 0.00 C ATOM 410 H5' C A 29 10.228 -8.081 -8.507 1.00 0.00 H ATOM 411 H5'' C A 29 10.984 -9.673 -8.310 1.00 0.00 H ATOM 412 H4' C A 29 11.124 -8.319 -6.284 1.00 0.00 H ATOM 413 H3' C A 29 9.582 -10.893 -6.124 1.00 0.00 H ATOM 414 H2' C A 29 9.150 -10.442 -3.808 1.00 0.00 H ATOM 415 HO2' C A 29 11.249 -8.565 -4.145 1.00 0.00 H ATOM 416 H1' C A 29 8.649 -7.683 -4.144 1.00 0.00 H ATOM 417 H41 C A 29 2.896 -10.416 -3.942 1.00 0.00 H ATOM 418 H42 C A 29 2.939 -10.598 -5.681 1.00 0.00 H ATOM 419 H5 C A 29 4.897 -10.108 -7.010 1.00 0.00 H ATOM 420 H6 C A 29 7.205 -9.326 -6.946 1.00 0.00 H ATOM 421 P C A 30 11.723 -12.177 -5.120 1.00 0.00 P ATOM 422 OP1 C A 30 13.182 -12.421 -4.988 1.00 0.00 O ATOM 423 OP2 C A 30 10.921 -13.020 -6.043 1.00 0.00 O ATOM 424 O5' C A 30 11.066 -12.266 -3.672 1.00 0.00 O ATOM 425 C5' C A 30 11.746 -11.773 -2.520 1.00 0.00 C ATOM 426 C4' C A 30 10.940 -12.072 -1.280 1.00 0.00 C ATOM 427 O4' C A 30 9.543 -11.739 -1.532 1.00 0.00 O ATOM 428 C3' C A 30 10.942 -13.540 -0.852 1.00 0.00 C ATOM 429 O3' C A 30 11.027 -13.671 0.564 1.00 0.00 O ATOM 430 C2' C A 30 9.620 -14.074 -1.394 1.00 0.00 C ATOM 431 O2' C A 30 9.109 -15.135 -0.611 1.00 0.00 O ATOM 432 C1' C A 30 8.734 -12.853 -1.222 1.00 0.00 C ATOM 433 N1 C A 30 7.551 -12.857 -2.106 1.00 0.00 N ATOM 434 C2 C A 30 6.272 -12.970 -1.536 1.00 0.00 C ATOM 435 O2 C A 30 6.163 -13.047 -0.304 1.00 0.00 O ATOM 436 N3 C A 30 5.187 -12.991 -2.348 1.00 0.00 N ATOM 437 C4 C A 30 5.339 -12.905 -3.673 1.00 0.00 C ATOM 438 N4 C A 30 4.240 -12.943 -4.429 1.00 0.00 N ATOM 439 C5 C A 30 6.624 -12.780 -4.282 1.00 0.00 C ATOM 440 C6 C A 30 7.692 -12.760 -3.469 1.00 0.00 C ATOM 441 H5' C A 30 11.891 -10.695 -2.605 1.00 0.00 H ATOM 442 H5'' C A 30 12.720 -12.254 -2.433 1.00 0.00 H ATOM 443 H4' C A 30 11.382 -11.507 -0.458 1.00 0.00 H ATOM 444 H3' C A 30 11.802 -14.070 -1.257 1.00 0.00 H ATOM 445 H2' C A 30 9.721 -14.341 -2.446 1.00 0.00 H ATOM 446 HO2' C A 30 8.714 -14.747 0.170 1.00 0.00 H ATOM 447 H1' C A 30 8.399 -12.730 -0.195 1.00 0.00 H ATOM 448 H41 C A 30 3.333 -13.034 -3.996 1.00 0.00 H ATOM 449 H42 C A 30 4.316 -12.882 -5.434 1.00 0.00 H ATOM 450 H5 C A 30 6.734 -12.703 -5.363 1.00 0.00 H ATOM 451 H6 C A 30 8.688 -12.664 -3.902 1.00 0.00 H ATOM 452 P U A 31 12.385 -14.209 1.243 1.00 0.00 P ATOM 453 OP1 U A 31 12.041 -14.695 2.604 1.00 0.00 O ATOM 454 OP2 U A 31 13.430 -13.167 1.081 1.00 0.00 O ATOM 455 O5' U A 31 12.795 -15.470 0.356 1.00 0.00 O ATOM 456 C5' U A 31 11.928 -16.595 0.228 1.00 0.00 C ATOM 457 C4' U A 31 11.986 -17.154 -1.180 1.00 0.00 C ATOM 458 O4' U A 31 12.384 -16.096 -2.103 1.00 0.00 O ATOM 459 C3' U A 31 12.996 -18.287 -1.392 1.00 0.00 C ATOM 460 O3' U A 31 12.436 -19.312 -2.221 1.00 0.00 O ATOM 461 C2' U A 31 14.189 -17.580 -2.041 1.00 0.00 C ATOM 462 O2' U A 31 14.939 -18.429 -2.887 1.00 0.00 O ATOM 463 C1' U A 31 13.474 -16.539 -2.881 1.00 0.00 C ATOM 464 N1 U A 31 14.319 -15.381 -3.237 1.00 0.00 N ATOM 465 C2 U A 31 14.856 -15.339 -4.519 1.00 0.00 C ATOM 466 O2 U A 31 14.655 -16.206 -5.353 1.00 0.00 O ATOM 467 N3 U A 31 15.639 -14.238 -4.786 1.00 0.00 N ATOM 468 C4 U A 31 15.932 -13.198 -3.923 1.00 0.00 C ATOM 469 O4 U A 31 16.655 -12.277 -4.309 1.00 0.00 O ATOM 470 C5 U A 31 15.340 -13.314 -2.623 1.00 0.00 C ATOM 471 C6 U A 31 14.573 -14.373 -2.326 1.00 0.00 C ATOM 472 H5' U A 31 10.903 -16.299 0.454 1.00 0.00 H ATOM 473 H5'' U A 31 12.231 -17.371 0.929 1.00 0.00 H ATOM 474 H4' U A 31 11.003 -17.571 -1.400 1.00 0.00 H ATOM 475 H3' U A 31 13.254 -18.763 -0.455 1.00 0.00 H ATOM 476 H2' U A 31 14.806 -17.106 -1.277 1.00 0.00 H ATOM 477 HO2' U A 31 15.500 -17.872 -3.425 1.00 0.00 H ATOM 478 H1' U A 31 13.063 -16.960 -3.797 1.00 0.00 H ATOM 479 H3 U A 31 16.046 -14.186 -5.710 1.00 0.00 H ATOM 480 H5 U A 31 15.511 -12.538 -1.877 1.00 0.00 H ATOM 481 H6 U A 31 14.139 -14.442 -1.330 1.00 0.00 H ATOM 482 P G A 32 13.161 -20.746 -2.416 1.00 0.00 P ATOM 483 OP1 G A 32 14.015 -20.660 -3.627 1.00 0.00 O ATOM 484 OP2 G A 32 12.108 -21.792 -2.364 1.00 0.00 O ATOM 485 O5' G A 32 14.129 -20.927 -1.144 1.00 0.00 O ATOM 486 C5' G A 32 13.697 -20.963 0.236 1.00 0.00 C ATOM 487 C4' G A 32 12.236 -21.354 0.397 1.00 0.00 C ATOM 488 O4' G A 32 12.164 -22.774 0.676 1.00 0.00 O ATOM 489 C3' G A 32 11.515 -20.715 1.572 1.00 0.00 C ATOM 490 O3' G A 32 10.101 -20.747 1.390 1.00 0.00 O ATOM 491 C2' G A 32 11.949 -21.593 2.740 1.00 0.00 C ATOM 492 O2' G A 32 10.983 -21.617 3.775 1.00 0.00 O ATOM 493 C1' G A 32 12.012 -22.974 2.074 1.00 0.00 C ATOM 494 N9 G A 32 13.122 -23.804 2.544 1.00 0.00 N ATOM 495 C8 G A 32 14.409 -23.400 2.808 1.00 0.00 C ATOM 496 N7 G A 32 15.182 -24.368 3.217 1.00 0.00 N ATOM 497 C5 G A 32 14.357 -25.483 3.225 1.00 0.00 C ATOM 498 C6 G A 32 14.635 -26.833 3.581 1.00 0.00 C ATOM 499 O6 G A 32 15.705 -27.317 3.970 1.00 0.00 O ATOM 500 N1 G A 32 13.512 -27.654 3.448 1.00 0.00 N ATOM 501 C2 G A 32 12.274 -27.216 3.023 1.00 0.00 C ATOM 502 N2 G A 32 11.310 -28.146 2.956 1.00 0.00 N ATOM 503 N3 G A 32 12.003 -25.960 2.689 1.00 0.00 N ATOM 504 C4 G A 32 13.081 -25.153 2.813 1.00 0.00 C ATOM 505 H5' G A 32 13.858 -19.986 0.693 1.00 0.00 H ATOM 506 H5'' G A 32 14.302 -21.690 0.774 1.00 0.00 H ATOM 507 H4' G A 32 11.698 -21.052 -0.493 1.00 0.00 H ATOM 508 H3' G A 32 11.786 -19.668 1.701 1.00 0.00 H ATOM 509 H2' G A 32 12.932 -21.283 3.098 1.00 0.00 H ATOM 510 HO2' G A 32 10.131 -21.447 3.373 1.00 0.00 H ATOM 511 H1' G A 32 11.090 -23.535 2.215 1.00 0.00 H ATOM 512 H8 G A 32 14.748 -22.382 2.691 1.00 0.00 H ATOM 513 H1 G A 32 13.613 -28.633 3.678 1.00 0.00 H ATOM 514 H21 G A 32 11.512 -29.102 3.208 1.00 0.00 H ATOM 515 H22 G A 32 10.382 -27.889 2.652 1.00 0.00 H ATOM 516 P G A 33 9.364 -19.590 0.550 1.00 0.00 P ATOM 517 OP1 G A 33 9.899 -19.604 -0.836 1.00 0.00 O ATOM 518 OP2 G A 33 9.437 -18.343 1.352 1.00 0.00 O ATOM 519 O5' G A 33 7.840 -20.061 0.507 1.00 0.00 O ATOM 520 C5' G A 33 7.239 -20.518 -0.704 1.00 0.00 C ATOM 521 C4' G A 33 6.006 -21.340 -0.403 1.00 0.00 C ATOM 522 O4' G A 33 6.419 -22.704 -0.108 1.00 0.00 O ATOM 523 C3' G A 33 5.191 -20.887 0.810 1.00 0.00 C ATOM 524 O3' G A 33 3.793 -21.084 0.596 1.00 0.00 O ATOM 525 C2' G A 33 5.720 -21.768 1.939 1.00 0.00 C ATOM 526 O2' G A 33 4.748 -22.007 2.939 1.00 0.00 O ATOM 527 C1' G A 33 5.996 -23.063 1.191 1.00 0.00 C ATOM 528 N9 G A 33 7.031 -23.884 1.815 1.00 0.00 N ATOM 529 C8 G A 33 8.364 -23.940 1.485 1.00 0.00 C ATOM 530 N7 G A 33 9.046 -24.767 2.230 1.00 0.00 N ATOM 531 C5 G A 33 8.106 -25.292 3.106 1.00 0.00 C ATOM 532 C6 G A 33 8.250 -26.244 4.155 1.00 0.00 C ATOM 533 O6 G A 33 9.276 -26.828 4.524 1.00 0.00 O ATOM 534 N1 G A 33 7.036 -26.499 4.803 1.00 0.00 N ATOM 535 C2 G A 33 5.837 -25.902 4.472 1.00 0.00 C ATOM 536 N2 G A 33 4.772 -26.266 5.200 1.00 0.00 N ATOM 537 N3 G A 33 5.693 -25.013 3.498 1.00 0.00 N ATOM 538 C4 G A 33 6.857 -24.757 2.862 1.00 0.00 C ATOM 539 H5' G A 33 7.951 -21.131 -1.260 1.00 0.00 H ATOM 540 H5'' G A 33 6.954 -19.664 -1.319 1.00 0.00 H ATOM 541 H4' G A 33 5.346 -21.266 -1.268 1.00 0.00 H ATOM 542 H3' G A 33 5.321 -19.825 1.009 1.00 0.00 H ATOM 543 H2' G A 33 6.640 -21.347 2.345 1.00 0.00 H ATOM 544 HO2' G A 33 3.940 -22.262 2.495 1.00 0.00 H ATOM 545 H1' G A 33 5.101 -23.671 1.081 1.00 0.00 H ATOM 546 H8 G A 33 8.805 -23.357 0.689 1.00 0.00 H ATOM 547 H1 G A 33 7.038 -27.164 5.564 1.00 0.00 H ATOM 548 H21 G A 33 4.874 -26.942 5.942 1.00 0.00 H ATOM 549 H22 G A 33 3.866 -25.863 5.005 1.00 0.00 H ATOM 550 P G A 34 2.728 -19.987 1.106 1.00 0.00 P ATOM 551 OP1 G A 34 1.363 -20.484 0.791 1.00 0.00 O ATOM 552 OP2 G A 34 3.161 -18.665 0.583 1.00 0.00 O ATOM 553 O5' G A 34 2.900 -19.980 2.693 1.00 0.00 O ATOM 554 C5' G A 34 3.924 -19.213 3.329 1.00 0.00 C ATOM 555 C4' G A 34 3.313 -18.142 4.202 1.00 0.00 C ATOM 556 O4' G A 34 4.342 -17.168 4.535 1.00 0.00 O ATOM 557 C3' G A 34 2.189 -17.330 3.558 1.00 0.00 C ATOM 558 O3' G A 34 1.232 -16.915 4.529 1.00 0.00 O ATOM 559 C2' G A 34 2.930 -16.142 2.959 1.00 0.00 C ATOM 560 O2' G A 34 2.101 -15.001 2.830 1.00 0.00 O ATOM 561 C1' G A 34 3.973 -15.896 4.041 1.00 0.00 C ATOM 562 N9 G A 34 5.176 -15.212 3.567 1.00 0.00 N ATOM 563 C8 G A 34 5.303 -14.435 2.441 1.00 0.00 C ATOM 564 N7 G A 34 6.504 -13.954 2.276 1.00 0.00 N ATOM 565 C5 G A 34 7.219 -14.442 3.360 1.00 0.00 C ATOM 566 C6 G A 34 8.583 -14.259 3.723 1.00 0.00 C ATOM 567 O6 G A 34 9.451 -13.604 3.132 1.00 0.00 O ATOM 568 N1 G A 34 8.908 -14.933 4.904 1.00 0.00 N ATOM 569 C2 G A 34 8.017 -15.689 5.638 1.00 0.00 C ATOM 570 N2 G A 34 8.503 -16.266 6.745 1.00 0.00 N ATOM 571 N3 G A 34 6.743 -15.866 5.309 1.00 0.00 N ATOM 572 C4 G A 34 6.414 -15.220 4.168 1.00 0.00 C ATOM 573 H5' G A 34 4.558 -18.743 2.575 1.00 0.00 H ATOM 574 H5'' G A 34 4.538 -19.863 3.949 1.00 0.00 H ATOM 575 H4' G A 34 2.886 -18.636 5.075 1.00 0.00 H ATOM 576 H3' G A 34 1.641 -17.906 2.814 1.00 0.00 H ATOM 577 H2' G A 34 3.401 -16.425 2.016 1.00 0.00 H ATOM 578 HO2' G A 34 1.951 -14.862 1.895 1.00 0.00 H ATOM 579 H1' G A 34 3.568 -15.332 4.879 1.00 0.00 H ATOM 580 H8 G A 34 4.489 -14.241 1.759 1.00 0.00 H ATOM 581 H1 G A 34 9.857 -14.861 5.243 1.00 0.00 H ATOM 582 H21 G A 34 9.472 -16.137 6.998 1.00 0.00 H ATOM 583 H22 G A 34 7.902 -16.833 7.326 1.00 0.00 H ATOM 584 P A A 35 0.049 -17.909 4.972 1.00 0.00 P ATOM 585 OP1 A A 35 0.645 -18.944 5.855 1.00 0.00 O ATOM 586 OP2 A A 35 -0.693 -18.325 3.754 1.00 0.00 O ATOM 587 O5' A A 35 -0.908 -16.993 5.862 1.00 0.00 O ATOM 588 C5' A A 35 -1.926 -16.186 5.272 1.00 0.00 C ATOM 589 C4' A A 35 -1.389 -14.804 4.969 1.00 0.00 C ATOM 590 O4' A A 35 -0.546 -14.877 3.787 1.00 0.00 O ATOM 591 C3' A A 35 -2.446 -13.760 4.623 1.00 0.00 C ATOM 592 O3' A A 35 -1.994 -12.435 4.905 1.00 0.00 O ATOM 593 C2' A A 35 -2.628 -13.976 3.126 1.00 0.00 C ATOM 594 O2' A A 35 -3.128 -12.823 2.473 1.00 0.00 O ATOM 595 C1' A A 35 -1.180 -14.212 2.709 1.00 0.00 C ATOM 596 N9 A A 35 -1.030 -15.033 1.506 1.00 0.00 N ATOM 597 C8 A A 35 -1.389 -16.348 1.331 1.00 0.00 C ATOM 598 N7 A A 35 -1.123 -16.815 0.135 1.00 0.00 N ATOM 599 C5 A A 35 -0.553 -15.736 -0.525 1.00 0.00 C ATOM 600 C6 A A 35 -0.050 -15.576 -1.834 1.00 0.00 C ATOM 601 N6 A A 35 -0.043 -16.548 -2.749 1.00 0.00 N ATOM 602 N1 A A 35 0.454 -14.364 -2.176 1.00 0.00 N ATOM 603 C2 A A 35 0.449 -13.383 -1.259 1.00 0.00 C ATOM 604 N3 A A 35 0.005 -13.412 0.000 1.00 0.00 N ATOM 605 C4 A A 35 -0.489 -14.630 0.309 1.00 0.00 C ATOM 606 H5' A A 35 -2.769 -16.100 5.959 1.00 0.00 H ATOM 607 H5'' A A 35 -2.272 -16.642 4.345 1.00 0.00 H ATOM 608 H4' A A 35 -0.867 -14.451 5.858 1.00 0.00 H ATOM 609 H3' A A 35 -3.366 -13.901 5.190 1.00 0.00 H ATOM 610 H2' A A 35 -3.240 -14.860 2.942 1.00 0.00 H ATOM 611 HO2' A A 35 -2.644 -12.071 2.812 1.00 0.00 H ATOM 612 H1' A A 35 -0.644 -13.278 2.552 1.00 0.00 H ATOM 613 H8 A A 35 -1.848 -16.942 2.107 1.00 0.00 H ATOM 614 H61 A A 35 0.331 -16.372 -3.670 1.00 0.00 H ATOM 615 H62 A A 35 -0.412 -17.460 -2.520 1.00 0.00 H ATOM 616 H2 A A 35 0.865 -12.431 -1.589 1.00 0.00 H ATOM 617 P G A 36 -1.678 -11.968 6.414 1.00 0.00 P ATOM 618 OP1 G A 36 -2.045 -13.083 7.325 1.00 0.00 O ATOM 619 OP2 G A 36 -2.281 -10.627 6.620 1.00 0.00 O ATOM 620 O5' G A 36 -0.091 -11.811 6.436 1.00 0.00 O ATOM 621 C5' G A 36 0.567 -10.900 5.557 1.00 0.00 C ATOM 622 C4' G A 36 2.058 -11.155 5.558 1.00 0.00 C ATOM 623 O4' G A 36 2.373 -12.180 4.573 1.00 0.00 O ATOM 624 C3' G A 36 2.921 -9.964 5.167 1.00 0.00 C ATOM 625 O3' G A 36 3.224 -9.151 6.297 1.00 0.00 O ATOM 626 C2' G A 36 4.159 -10.632 4.588 1.00 0.00 C ATOM 627 O2' G A 36 5.006 -11.156 5.594 1.00 0.00 O ATOM 628 C1' G A 36 3.509 -11.782 3.821 1.00 0.00 C ATOM 629 N9 G A 36 3.067 -11.419 2.473 1.00 0.00 N ATOM 630 C8 G A 36 1.793 -11.514 1.967 1.00 0.00 C ATOM 631 N7 G A 36 1.696 -11.115 0.731 1.00 0.00 N ATOM 632 C5 G A 36 2.985 -10.732 0.392 1.00 0.00 C ATOM 633 C6 G A 36 3.500 -10.210 -0.827 1.00 0.00 C ATOM 634 O6 G A 36 2.892 -9.980 -1.879 1.00 0.00 O ATOM 635 N1 G A 36 4.870 -9.950 -0.750 1.00 0.00 N ATOM 636 C2 G A 36 5.642 -10.170 0.371 1.00 0.00 C ATOM 637 N2 G A 36 6.943 -9.862 0.260 1.00 0.00 N ATOM 638 N3 G A 36 5.174 -10.657 1.516 1.00 0.00 N ATOM 639 C4 G A 36 3.846 -10.913 1.456 1.00 0.00 C ATOM 640 H5' G A 36 0.379 -9.875 5.881 1.00 0.00 H ATOM 641 H5'' G A 36 0.188 -11.025 4.543 1.00 0.00 H ATOM 642 H4' G A 36 2.342 -11.428 6.576 1.00 0.00 H ATOM 643 H3' G A 36 2.418 -9.318 4.449 1.00 0.00 H ATOM 644 H2' G A 36 4.680 -9.948 3.914 1.00 0.00 H ATOM 645 HO2' G A 36 5.878 -10.788 5.453 1.00 0.00 H ATOM 646 H1' G A 36 4.163 -12.650 3.745 1.00 0.00 H ATOM 647 H8 G A 36 0.955 -11.883 2.538 1.00 0.00 H ATOM 648 H1 G A 36 5.325 -9.576 -1.569 1.00 0.00 H ATOM 649 H21 G A 36 7.301 -9.492 -0.609 1.00 0.00 H ATOM 650 H22 G A 36 7.563 -10.000 1.045 1.00 0.00 H ATOM 651 P C A 37 3.071 -7.552 6.208 1.00 0.00 P ATOM 652 OP1 C A 37 3.204 -7.018 7.588 1.00 0.00 O ATOM 653 OP2 C A 37 1.854 -7.238 5.416 1.00 0.00 O ATOM 654 O5' C A 37 4.346 -7.088 5.371 1.00 0.00 O ATOM 655 C5' C A 37 5.668 -7.325 5.852 1.00 0.00 C ATOM 656 C4' C A 37 6.677 -7.079 4.753 1.00 0.00 C ATOM 657 O4' C A 37 6.410 -7.980 3.647 1.00 0.00 O ATOM 658 C3' C A 37 6.639 -5.697 4.124 1.00 0.00 C ATOM 659 O3' C A 37 7.381 -4.754 4.891 1.00 0.00 O ATOM 660 C2' C A 37 7.271 -5.947 2.761 1.00 0.00 C ATOM 661 O2' C A 37 8.682 -6.036 2.836 1.00 0.00 O ATOM 662 C1' C A 37 6.693 -7.323 2.419 1.00 0.00 C ATOM 663 N1 C A 37 5.458 -7.255 1.606 1.00 0.00 N ATOM 664 C2 C A 37 5.549 -6.805 0.278 1.00 0.00 C ATOM 665 O2 C A 37 6.657 -6.480 -0.175 1.00 0.00 O ATOM 666 N3 C A 37 4.423 -6.736 -0.474 1.00 0.00 N ATOM 667 C4 C A 37 3.244 -7.094 0.046 1.00 0.00 C ATOM 668 N4 C A 37 2.165 -7.009 -0.734 1.00 0.00 N ATOM 669 C5 C A 37 3.120 -7.557 1.392 1.00 0.00 C ATOM 670 C6 C A 37 4.240 -7.621 2.128 1.00 0.00 C ATOM 671 H5' C A 37 5.756 -8.356 6.196 1.00 0.00 H ATOM 672 H5'' C A 37 5.883 -6.655 6.685 1.00 0.00 H ATOM 673 H4' C A 37 7.671 -7.203 5.185 1.00 0.00 H ATOM 674 H3' C A 37 5.624 -5.308 4.055 1.00 0.00 H ATOM 675 H2' C A 37 6.939 -5.190 2.047 1.00 0.00 H ATOM 676 HO2' C A 37 9.038 -5.226 2.472 1.00 0.00 H ATOM 677 H1' C A 37 7.412 -7.947 1.885 1.00 0.00 H ATOM 678 H41 C A 37 2.254 -6.680 -1.685 1.00 0.00 H ATOM 679 H42 C A 37 1.259 -7.272 -0.373 1.00 0.00 H ATOM 680 H5 C A 37 2.154 -7.848 1.804 1.00 0.00 H ATOM 681 H6 C A 37 4.178 -7.970 3.158 1.00 0.00 H ATOM 682 P U A 38 7.093 -3.179 4.729 1.00 0.00 P ATOM 683 OP1 U A 38 8.019 -2.442 5.626 1.00 0.00 O ATOM 684 OP2 U A 38 5.628 -2.977 4.864 1.00 0.00 O ATOM 685 O5' U A 38 7.498 -2.863 3.219 1.00 0.00 O ATOM 686 C5' U A 38 8.864 -2.696 2.845 1.00 0.00 C ATOM 687 C4' U A 38 8.982 -2.508 1.348 1.00 0.00 C ATOM 688 O4' U A 38 8.206 -3.525 0.668 1.00 0.00 O ATOM 689 C3' U A 38 8.428 -1.207 0.801 1.00 0.00 C ATOM 690 O3' U A 38 9.355 -0.136 0.970 1.00 0.00 O ATOM 691 C2' U A 38 8.203 -1.547 -0.669 1.00 0.00 C ATOM 692 O2' U A 38 9.398 -1.467 -1.423 1.00 0.00 O ATOM 693 C1' U A 38 7.760 -3.014 -0.581 1.00 0.00 C ATOM 694 N1 U A 38 6.297 -3.191 -0.682 1.00 0.00 N ATOM 695 C2 U A 38 5.734 -3.187 -1.953 1.00 0.00 C ATOM 696 O2 U A 38 6.391 -3.042 -2.971 1.00 0.00 O ATOM 697 N3 U A 38 4.370 -3.359 -1.986 1.00 0.00 N ATOM 698 C4 U A 38 3.528 -3.528 -0.903 1.00 0.00 C ATOM 699 O4 U A 38 2.320 -3.674 -1.093 1.00 0.00 O ATOM 700 C5 U A 38 4.183 -3.517 0.372 1.00 0.00 C ATOM 701 C6 U A 38 5.511 -3.353 0.443 1.00 0.00 C ATOM 702 H5' U A 38 9.437 -3.575 3.142 1.00 0.00 H ATOM 703 H5'' U A 38 9.277 -1.820 3.343 1.00 0.00 H ATOM 704 H4' U A 38 10.043 -2.531 1.097 1.00 0.00 H ATOM 705 H3' U A 38 7.515 -0.906 1.312 1.00 0.00 H ATOM 706 H2' U A 38 7.409 -0.922 -1.081 1.00 0.00 H ATOM 707 HO2' U A 38 9.466 -0.571 -1.755 1.00 0.00 H ATOM 708 H1' U A 38 8.225 -3.628 -1.355 1.00 0.00 H ATOM 709 H3 U A 38 3.938 -3.362 -2.899 1.00 0.00 H ATOM 710 H5 U A 38 3.600 -3.641 1.284 1.00 0.00 H ATOM 711 H6 U A 38 5.985 -3.345 1.423 1.00 0.00 H ATOM 712 P C A 39 8.962 1.352 0.499 1.00 0.00 P ATOM 713 OP1 C A 39 9.985 2.290 1.028 1.00 0.00 O ATOM 714 OP2 C A 39 7.530 1.564 0.834 1.00 0.00 O ATOM 715 O5' C A 39 9.104 1.301 -1.088 1.00 0.00 O ATOM 716 C5' C A 39 8.309 2.129 -1.934 1.00 0.00 C ATOM 717 C4' C A 39 8.231 1.527 -3.318 1.00 0.00 C ATOM 718 O4' C A 39 7.675 0.186 -3.223 1.00 0.00 O ATOM 719 C3' C A 39 7.318 2.252 -4.296 1.00 0.00 C ATOM 720 O3' C A 39 8.003 3.304 -4.970 1.00 0.00 O ATOM 721 C2' C A 39 6.908 1.138 -5.248 1.00 0.00 C ATOM 722 O2' C A 39 7.934 0.814 -6.170 1.00 0.00 O ATOM 723 C1' C A 39 6.729 -0.014 -4.263 1.00 0.00 C ATOM 724 N1 C A 39 5.371 -0.089 -3.678 1.00 0.00 N ATOM 725 C2 C A 39 4.291 -0.410 -4.517 1.00 0.00 C ATOM 726 O2 C A 39 4.502 -0.610 -5.723 1.00 0.00 O ATOM 727 N3 C A 39 3.044 -0.491 -3.991 1.00 0.00 N ATOM 728 C4 C A 39 2.850 -0.264 -2.687 1.00 0.00 C ATOM 729 N4 C A 39 1.606 -0.357 -2.215 1.00 0.00 N ATOM 730 C5 C A 39 3.925 0.069 -1.808 1.00 0.00 C ATOM 731 C6 C A 39 5.156 0.145 -2.339 1.00 0.00 C ATOM 732 H5' C A 39 8.751 3.124 -1.998 1.00 0.00 H ATOM 733 H5'' C A 39 7.301 2.215 -1.528 1.00 0.00 H ATOM 734 H4' C A 39 9.235 1.553 -3.744 1.00 0.00 H ATOM 735 H3' C A 39 6.467 2.710 -3.793 1.00 0.00 H ATOM 736 H2' C A 39 5.967 1.386 -5.740 1.00 0.00 H ATOM 737 HO2' C A 39 7.688 1.193 -7.015 1.00 0.00 H ATOM 738 H1' C A 39 6.954 -0.980 -4.717 1.00 0.00 H ATOM 739 H41 C A 39 0.845 -0.587 -2.837 1.00 0.00 H ATOM 740 H42 C A 39 1.425 -0.192 -1.235 1.00 0.00 H ATOM 741 H5 C A 39 3.752 0.257 -0.749 1.00 0.00 H ATOM 742 H6 C A 39 5.996 0.400 -1.695 1.00 0.00 H ATOM 743 P U A 40 7.572 4.835 -4.720 1.00 0.00 P ATOM 744 OP1 U A 40 8.518 5.690 -5.481 1.00 0.00 O ATOM 745 OP2 U A 40 7.410 5.042 -3.258 1.00 0.00 O ATOM 746 O5' U A 40 6.134 4.950 -5.402 1.00 0.00 O ATOM 747 C5' U A 40 5.992 5.178 -6.805 1.00 0.00 C ATOM 748 C4' U A 40 4.995 4.207 -7.401 1.00 0.00 C ATOM 749 O4' U A 40 4.817 3.083 -6.502 1.00 0.00 O ATOM 750 C3' U A 40 3.589 4.746 -7.597 1.00 0.00 C ATOM 751 O3' U A 40 3.480 5.479 -8.815 1.00 0.00 O ATOM 752 C2' U A 40 2.755 3.470 -7.625 1.00 0.00 C ATOM 753 O2' U A 40 2.817 2.821 -8.882 1.00 0.00 O ATOM 754 C1' U A 40 3.479 2.615 -6.577 1.00 0.00 C ATOM 755 N1 U A 40 2.867 2.672 -5.228 1.00 0.00 N ATOM 756 C2 U A 40 1.548 2.252 -5.098 1.00 0.00 C ATOM 757 O2 U A 40 0.881 1.852 -6.036 1.00 0.00 O ATOM 758 N3 U A 40 1.038 2.321 -3.822 1.00 0.00 N ATOM 759 C4 U A 40 1.690 2.760 -2.688 1.00 0.00 C ATOM 760 O4 U A 40 1.096 2.753 -1.608 1.00 0.00 O ATOM 761 C5 U A 40 3.042 3.181 -2.902 1.00 0.00 C ATOM 762 C6 U A 40 3.578 3.125 -4.130 1.00 0.00 C ATOM 763 H5' U A 40 6.956 5.049 -7.300 1.00 0.00 H ATOM 764 H5'' U A 40 5.640 6.195 -6.978 1.00 0.00 H ATOM 765 H4' U A 40 5.365 3.920 -8.387 1.00 0.00 H ATOM 766 H3' U A 40 3.298 5.426 -6.798 1.00 0.00 H ATOM 767 H2' U A 40 1.731 3.684 -7.320 1.00 0.00 H ATOM 768 HO2' U A 40 2.148 2.138 -8.882 1.00 0.00 H ATOM 769 H1' U A 40 3.531 1.568 -6.875 1.00 0.00 H ATOM 770 H3 U A 40 0.086 2.009 -3.700 1.00 0.00 H ATOM 771 H5 U A 40 3.634 3.554 -2.066 1.00 0.00 H ATOM 772 H6 U A 40 4.611 3.442 -4.265 1.00 0.00 H ATOM 773 P C A 41 2.465 6.724 -8.923 1.00 0.00 P ATOM 774 OP1 C A 41 2.573 7.295 -10.290 1.00 0.00 O ATOM 775 OP2 C A 41 2.701 7.597 -7.745 1.00 0.00 O ATOM 776 O5' C A 41 1.023 6.064 -8.767 1.00 0.00 O ATOM 777 C5' C A 41 0.367 5.457 -9.878 1.00 0.00 C ATOM 778 C4' C A 41 -0.839 4.675 -9.411 1.00 0.00 C ATOM 779 O4' C A 41 -0.488 3.922 -8.226 1.00 0.00 O ATOM 780 C3' C A 41 -2.036 5.506 -8.984 1.00 0.00 C ATOM 781 O3' C A 41 -2.834 5.876 -10.106 1.00 0.00 O ATOM 782 C2' C A 41 -2.780 4.561 -8.045 1.00 0.00 C ATOM 783 O2' C A 41 -3.594 3.643 -8.751 1.00 0.00 O ATOM 784 C1' C A 41 -1.622 3.803 -7.383 1.00 0.00 C ATOM 785 N1 C A 41 -1.280 4.303 -6.033 1.00 0.00 N ATOM 786 C2 C A 41 -2.213 4.132 -5.001 1.00 0.00 C ATOM 787 O2 C A 41 -3.301 3.595 -5.258 1.00 0.00 O ATOM 788 N3 C A 41 -1.905 4.558 -3.751 1.00 0.00 N ATOM 789 C4 C A 41 -0.725 5.140 -3.512 1.00 0.00 C ATOM 790 N4 C A 41 -0.461 5.530 -2.262 1.00 0.00 N ATOM 791 C5 C A 41 0.240 5.345 -4.545 1.00 0.00 C ATOM 792 C6 C A 41 -0.076 4.918 -5.778 1.00 0.00 C ATOM 793 H5' C A 41 1.056 4.782 -10.389 1.00 0.00 H ATOM 794 H5'' C A 41 0.040 6.225 -10.578 1.00 0.00 H ATOM 795 H4' C A 41 -1.169 4.050 -10.242 1.00 0.00 H ATOM 796 H3' C A 41 -1.736 6.435 -8.501 1.00 0.00 H ATOM 797 H2' C A 41 -3.346 5.133 -7.308 1.00 0.00 H ATOM 798 HO2' C A 41 -4.434 4.072 -8.912 1.00 0.00 H ATOM 799 H1' C A 41 -1.835 2.736 -7.297 1.00 0.00 H ATOM 800 H41 C A 41 -1.143 5.379 -1.531 1.00 0.00 H ATOM 801 H42 C A 41 0.422 5.970 -2.046 1.00 0.00 H ATOM 802 H5 C A 41 1.195 5.828 -4.341 1.00 0.00 H ATOM 803 H6 C A 41 0.632 5.072 -6.589 1.00 0.00 H ATOM 804 P U A 42 -3.952 7.025 -9.962 1.00 0.00 P ATOM 805 OP1 U A 42 -4.634 7.175 -11.273 1.00 0.00 O ATOM 806 OP2 U A 42 -3.302 8.205 -9.337 1.00 0.00 O ATOM 807 O5' U A 42 -4.997 6.426 -8.916 1.00 0.00 O ATOM 808 C5' U A 42 -6.218 5.828 -9.345 1.00 0.00 C ATOM 809 C4' U A 42 -7.083 5.482 -8.151 1.00 0.00 C ATOM 810 O4' U A 42 -6.240 5.040 -7.056 1.00 0.00 O ATOM 811 C3' U A 42 -7.877 6.635 -7.562 1.00 0.00 C ATOM 812 O3' U A 42 -9.095 6.845 -8.271 1.00 0.00 O ATOM 813 C2' U A 42 -8.128 6.167 -6.134 1.00 0.00 C ATOM 814 O2' U A 42 -9.211 5.260 -6.053 1.00 0.00 O ATOM 815 C1' U A 42 -6.820 5.432 -5.820 1.00 0.00 C ATOM 816 N1 U A 42 -5.855 6.262 -5.068 1.00 0.00 N ATOM 817 C2 U A 42 -6.120 6.494 -3.724 1.00 0.00 C ATOM 818 O2 U A 42 -7.101 6.046 -3.153 1.00 0.00 O ATOM 819 N3 U A 42 -5.190 7.271 -3.074 1.00 0.00 N ATOM 820 C4 U A 42 -4.049 7.829 -3.613 1.00 0.00 C ATOM 821 O4 U A 42 -3.310 8.507 -2.897 1.00 0.00 O ATOM 822 C5 U A 42 -3.845 7.545 -5.003 1.00 0.00 C ATOM 823 C6 U A 42 -4.729 6.792 -5.671 1.00 0.00 C ATOM 824 H5' U A 42 -6.004 4.918 -9.907 1.00 0.00 H ATOM 825 H5'' U A 42 -6.763 6.520 -9.986 1.00 0.00 H ATOM 826 H4' U A 42 -7.806 4.733 -8.474 1.00 0.00 H ATOM 827 H3' U A 42 -7.328 7.574 -7.611 1.00 0.00 H ATOM 828 H2' U A 42 -8.261 7.028 -5.476 1.00 0.00 H ATOM 829 HO2' U A 42 -9.078 4.596 -6.729 1.00 0.00 H ATOM 830 H1' U A 42 -6.993 4.519 -5.249 1.00 0.00 H ATOM 831 H3 U A 42 -5.362 7.454 -2.096 1.00 0.00 H ATOM 832 H5 U A 42 -2.970 7.942 -5.517 1.00 0.00 H ATOM 833 H6 U A 42 -4.555 6.595 -6.726 1.00 0.00 H ATOM 834 P G A 43 -9.936 8.198 -8.040 1.00 0.00 P ATOM 835 OP1 G A 43 -11.214 8.084 -8.789 1.00 0.00 O ATOM 836 OP2 G A 43 -9.027 9.339 -8.315 1.00 0.00 O ATOM 837 O5' G A 43 -10.266 8.194 -6.478 1.00 0.00 O ATOM 838 C5' G A 43 -11.434 7.548 -5.975 1.00 0.00 C ATOM 839 C4' G A 43 -11.490 7.648 -4.467 1.00 0.00 C ATOM 840 O4' G A 43 -10.182 7.375 -3.912 1.00 0.00 O ATOM 841 C3' G A 43 -11.843 9.015 -3.912 1.00 0.00 C ATOM 842 O3' G A 43 -13.253 9.224 -3.928 1.00 0.00 O ATOM 843 C2' G A 43 -11.287 8.946 -2.489 1.00 0.00 C ATOM 844 O2' G A 43 -12.175 8.289 -1.604 1.00 0.00 O ATOM 845 C1' G A 43 -10.035 8.076 -2.687 1.00 0.00 C ATOM 846 N9 G A 43 -8.789 8.842 -2.730 1.00 0.00 N ATOM 847 C8 G A 43 -8.046 9.164 -3.841 1.00 0.00 C ATOM 848 N7 G A 43 -6.972 9.850 -3.564 1.00 0.00 N ATOM 849 C5 G A 43 -7.008 9.998 -2.184 1.00 0.00 C ATOM 850 C6 G A 43 -6.105 10.657 -1.303 1.00 0.00 C ATOM 851 O6 G A 43 -5.061 11.256 -1.584 1.00 0.00 O ATOM 852 N1 G A 43 -6.517 10.573 0.031 1.00 0.00 N ATOM 853 C2 G A 43 -7.663 9.930 0.451 1.00 0.00 C ATOM 854 N2 G A 43 -7.904 9.954 1.770 1.00 0.00 N ATOM 855 N3 G A 43 -8.511 9.311 -0.361 1.00 0.00 N ATOM 856 C4 G A 43 -8.125 9.384 -1.655 1.00 0.00 C ATOM 857 H5' G A 43 -11.424 6.497 -6.263 1.00 0.00 H ATOM 858 H5'' G A 43 -12.323 8.019 -6.392 1.00 0.00 H ATOM 859 H4' G A 43 -12.261 6.959 -4.121 1.00 0.00 H ATOM 860 H3' G A 43 -11.405 9.819 -4.501 1.00 0.00 H ATOM 861 H2' G A 43 -11.019 9.948 -2.139 1.00 0.00 H ATOM 862 HO2' G A 43 -12.477 8.939 -0.969 1.00 0.00 H ATOM 863 H1' G A 43 -9.936 7.323 -1.904 1.00 0.00 H ATOM 864 H8 G A 43 -8.326 8.884 -4.845 1.00 0.00 H ATOM 865 H1 G A 43 -5.938 11.012 0.732 1.00 0.00 H ATOM 866 H21 G A 43 -7.261 10.424 2.392 1.00 0.00 H ATOM 867 H22 G A 43 -8.727 9.503 2.141 1.00 0.00 H ATOM 868 P G A 44 -13.857 10.686 -3.637 1.00 0.00 P ATOM 869 OP1 G A 44 -15.336 10.574 -3.693 1.00 0.00 O ATOM 870 OP2 G A 44 -13.161 11.664 -4.512 1.00 0.00 O ATOM 871 O5' G A 44 -13.442 10.975 -2.128 1.00 0.00 O ATOM 872 C5' G A 44 -13.430 12.300 -1.605 1.00 0.00 C ATOM 873 C4' G A 44 -13.078 12.265 -0.137 1.00 0.00 C ATOM 874 O4' G A 44 -11.912 11.417 0.046 1.00 0.00 O ATOM 875 C3' G A 44 -12.684 13.601 0.475 1.00 0.00 C ATOM 876 O3' G A 44 -13.828 14.318 0.933 1.00 0.00 O ATOM 877 C2' G A 44 -11.777 13.178 1.623 1.00 0.00 C ATOM 878 O2' G A 44 -12.509 12.689 2.732 1.00 0.00 O ATOM 879 C1' G A 44 -11.020 12.025 0.963 1.00 0.00 C ATOM 880 N9 G A 44 -9.822 12.454 0.242 1.00 0.00 N ATOM 881 C8 G A 44 -9.594 12.390 -1.112 1.00 0.00 C ATOM 882 N7 G A 44 -8.426 12.854 -1.462 1.00 0.00 N ATOM 883 C5 G A 44 -7.844 13.249 -0.265 1.00 0.00 C ATOM 884 C6 G A 44 -6.571 13.830 -0.005 1.00 0.00 C ATOM 885 O6 G A 44 -5.681 14.118 -0.814 1.00 0.00 O ATOM 886 N1 G A 44 -6.375 14.078 1.357 1.00 0.00 N ATOM 887 C2 G A 44 -7.300 13.795 2.340 1.00 0.00 C ATOM 888 N2 G A 44 -6.942 14.102 3.595 1.00 0.00 N ATOM 889 N3 G A 44 -8.489 13.253 2.109 1.00 0.00 N ATOM 890 C4 G A 44 -8.693 13.008 0.796 1.00 0.00 C ATOM 891 H5' G A 44 -14.414 12.754 -1.728 1.00 0.00 H ATOM 892 H5'' G A 44 -12.691 12.901 -2.134 1.00 0.00 H ATOM 893 H4' G A 44 -13.958 11.916 0.404 1.00 0.00 H ATOM 894 H3' G A 44 -12.181 14.246 -0.244 1.00 0.00 H ATOM 895 H2' G A 44 -11.102 13.993 1.893 1.00 0.00 H ATOM 896 HO2' G A 44 -13.146 13.362 2.971 1.00 0.00 H ATOM 897 H1' G A 44 -10.728 11.256 1.679 1.00 0.00 H ATOM 898 H8 G A 44 -10.311 11.996 -1.817 1.00 0.00 H ATOM 899 H1 G A 44 -5.498 14.492 1.640 1.00 0.00 H ATOM 900 H21 G A 44 -6.039 14.515 3.776 1.00 0.00 H ATOM 901 H22 G A 44 -7.576 13.920 4.360 1.00 0.00 H ATOM 902 P C A 45 -13.918 15.915 0.741 1.00 0.00 P ATOM 903 OP1 C A 45 -15.311 16.340 1.032 1.00 0.00 O ATOM 904 OP2 C A 45 -13.312 16.246 -0.574 1.00 0.00 O ATOM 905 O5' C A 45 -12.970 16.496 1.883 1.00 0.00 O ATOM 906 C5' C A 45 -13.274 16.299 3.261 1.00 0.00 C ATOM 907 C4' C A 45 -12.081 16.660 4.116 1.00 0.00 C ATOM 908 O4' C A 45 -10.948 15.843 3.725 1.00 0.00 O ATOM 909 C3' C A 45 -11.580 18.086 3.973 1.00 0.00 C ATOM 910 O3' C A 45 -12.322 18.978 4.802 1.00 0.00 O ATOM 911 C2' C A 45 -10.127 17.972 4.418 1.00 0.00 C ATOM 912 O2' C A 45 -10.000 17.969 5.828 1.00 0.00 O ATOM 913 C1' C A 45 -9.749 16.589 3.872 1.00 0.00 C ATOM 914 N1 C A 45 -9.050 16.643 2.570 1.00 0.00 N ATOM 915 C2 C A 45 -7.698 17.019 2.547 1.00 0.00 C ATOM 916 O2 C A 45 -7.131 17.293 3.616 1.00 0.00 O ATOM 917 N3 C A 45 -7.046 17.075 1.360 1.00 0.00 N ATOM 918 C4 C A 45 -7.689 16.772 0.226 1.00 0.00 C ATOM 919 N4 C A 45 -7.005 16.841 -0.917 1.00 0.00 N ATOM 920 C5 C A 45 -9.063 16.384 0.216 1.00 0.00 C ATOM 921 C6 C A 45 -9.699 16.333 1.398 1.00 0.00 C ATOM 922 H5' C A 45 -13.536 15.254 3.435 1.00 0.00 H ATOM 923 H5'' C A 45 -14.116 16.927 3.547 1.00 0.00 H ATOM 924 H4' C A 45 -12.371 16.530 5.159 1.00 0.00 H ATOM 925 H3' C A 45 -11.682 18.453 2.954 1.00 0.00 H ATOM 926 H2' C A 45 -9.528 18.756 3.950 1.00 0.00 H ATOM 927 HO2' C A 45 -10.342 18.805 6.146 1.00 0.00 H ATOM 928 H1' C A 45 -9.118 16.035 4.567 1.00 0.00 H ATOM 929 H41 C A 45 -6.033 17.116 -0.909 1.00 0.00 H ATOM 930 H42 C A 45 -7.459 16.619 -1.792 1.00 0.00 H ATOM 931 H5 C A 45 -9.574 16.135 -0.713 1.00 0.00 H ATOM 932 H6 C A 45 -10.747 16.042 1.423 1.00 0.00 H ATOM 933 P C A 46 -12.833 20.393 4.227 1.00 0.00 P ATOM 934 OP1 C A 46 -13.901 20.901 5.126 1.00 0.00 O ATOM 935 OP2 C A 46 -13.121 20.216 2.780 1.00 0.00 O ATOM 936 O5' C A 46 -11.564 21.348 4.367 1.00 0.00 O ATOM 937 C5' C A 46 -11.175 21.875 5.633 1.00 0.00 C ATOM 938 C4' C A 46 -9.677 22.082 5.681 1.00 0.00 C ATOM 939 O4' C A 46 -9.011 20.941 5.090 1.00 0.00 O ATOM 940 C3' C A 46 -9.150 23.266 4.893 1.00 0.00 C ATOM 941 O3' C A 46 -9.267 24.485 5.630 1.00 0.00 O ATOM 942 C2' C A 46 -7.691 22.884 4.663 1.00 0.00 C ATOM 943 O2' C A 46 -6.884 23.171 5.790 1.00 0.00 O ATOM 944 C1' C A 46 -7.795 21.363 4.488 1.00 0.00 C ATOM 945 N1 C A 46 -7.788 20.934 3.076 1.00 0.00 N ATOM 946 C2 C A 46 -6.557 20.754 2.428 1.00 0.00 C ATOM 947 O2 C A 46 -5.508 20.964 3.057 1.00 0.00 O ATOM 948 N3 C A 46 -6.544 20.359 1.131 1.00 0.00 N ATOM 949 C4 C A 46 -7.695 20.147 0.483 1.00 0.00 C ATOM 950 N4 C A 46 -7.630 19.760 -0.793 1.00 0.00 N ATOM 951 C5 C A 46 -8.964 20.322 1.117 1.00 0.00 C ATOM 952 C6 C A 46 -8.962 20.714 2.402 1.00 0.00 C ATOM 953 H5' C A 46 -11.466 21.183 6.425 1.00 0.00 H ATOM 954 H5'' C A 46 -11.668 22.831 5.801 1.00 0.00 H ATOM 955 H4' C A 46 -9.404 22.251 6.719 1.00 0.00 H ATOM 956 H3' C A 46 -9.700 23.417 3.965 1.00 0.00 H ATOM 957 HO3' C A 46 -10.069 24.922 5.334 1.00 0.00 H ATOM 958 H2' C A 46 -7.317 23.361 3.753 1.00 0.00 H ATOM 959 HO2' C A 46 -6.145 23.697 5.484 1.00 0.00 H ATOM 960 H1' C A 46 -6.990 20.836 5.003 1.00 0.00 H ATOM 961 H41 C A 46 -6.732 19.638 -1.238 1.00 0.00 H ATOM 962 H42 C A 46 -8.479 19.591 -1.313 1.00 0.00 H ATOM 963 H5 C A 46 -9.896 20.146 0.579 1.00 0.00 H ATOM 964 H6 C A 46 -9.911 20.861 2.916 1.00 0.00 H TER 965 C A 46 HETATM 966 N ARG A 47 -1.746 -5.447 3.744 1.00 0.00 N HETATM 967 CA ARG A 47 -1.505 -5.526 2.273 1.00 0.00 C HETATM 968 C ARG A 47 -0.088 -6.053 2.014 1.00 0.00 C HETATM 969 O ARG A 47 0.081 -7.138 1.494 1.00 0.00 O HETATM 970 CB ARG A 47 -1.660 -4.132 1.650 1.00 0.00 C HETATM 971 CG ARG A 47 -2.735 -4.170 0.559 1.00 0.00 C HETATM 972 CD ARG A 47 -2.365 -3.193 -0.557 1.00 0.00 C HETATM 973 NE ARG A 47 -3.604 -2.749 -1.257 1.00 0.00 N HETATM 974 CZ ARG A 47 -3.622 -2.641 -2.561 1.00 0.00 C HETATM 975 NH1 ARG A 47 -2.604 -2.116 -3.193 1.00 0.00 N HETATM 976 NH2 ARG A 47 -4.658 -3.065 -3.234 1.00 0.00 N HETATM 977 H1 ARG A 47 -1.001 -4.872 4.189 1.00 0.00 H HETATM 978 H2 ARG A 47 -2.673 -5.010 3.921 1.00 0.00 H HETATM 979 H3 ARG A 47 -1.735 -6.404 4.150 1.00 0.00 H HETATM 980 HA ARG A 47 -2.224 -6.200 1.829 1.00 0.00 H HETATM 981 HB2 ARG A 47 -1.951 -3.427 2.416 1.00 0.00 H HETATM 982 HB3 ARG A 47 -0.721 -3.824 1.217 1.00 0.00 H HETATM 983 HG2 ARG A 47 -2.804 -5.170 0.153 1.00 0.00 H HETATM 984 HG3 ARG A 47 -3.688 -3.885 0.981 1.00 0.00 H HETATM 985 HD2 ARG A 47 -1.862 -2.335 -0.135 1.00 0.00 H HETATM 986 HD3 ARG A 47 -1.709 -3.684 -1.262 1.00 0.00 H HETATM 987 HE ARG A 47 -4.409 -2.537 -0.738 1.00 0.00 H HETATM 988 HH11 ARG A 47 -1.808 -1.794 -2.681 1.00 0.00 H HETATM 989 HH12 ARG A 47 -2.621 -2.038 -4.188 1.00 0.00 H HETATM 990 HH21 ARG A 47 -5.434 -3.472 -2.753 1.00 0.00 H HETATM 991 HH22 ARG A 47 -4.678 -2.978 -4.230 1.00 0.00 H MASTER 105 0 1 0 0 0 1 6 990 1 0 3 END