Murine norovirus protein NS1/2 aspartate to glutamate mutation, sufficient for persistence, reorients side chain of surface exposed tryptophan within a novel structured domain.

MRGSHHHHHHGS is a non-native affinity tag. The remainder represents residues 58-114 of the native protein.

Backbone 1h, 13c, And 15n Chemical Shift Assignments For Murine Norovirus Cr6 Ns1/2 Protein

polyprotein [Murine norovirus GV/CR6/2005/USA]

Case, Darden, Cheatham, III, Simmerling, Wang, Duke, Luo, ... and Kollman

Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax