It cleaves the carbon-mercury bond of alkylmercury and arylmercury compounds in the presence of cysteine or other thiols, releasing mercury as a mercaptide

1H, 15N, and 13C resonance assignment of the 23 kDa organomercurial lyase MerB in its free and mercury-bound forms.

The peptide bond between residues 137 and 138 is in the cis conformation

Solution Structure Of Merb, The Organomercurial Lyase Involved In The Bacterial Mercury Resistance System

Crystal Structure Of Merb, The Organomercurial Lyase Involved In A Bacterial Mercury Resistance System

Crystal Structure Of The Mercury-Bound Form Of Merb, The Organomercurial Lyase Involved In A Bacterial Mercury Resistance Syste

Crystal Structure Of Merb Mutant C160s, The Organomercurial Lyase Involved In A Bacterial Mercury Resistance System

Crystal Structure Of The Mercury-Bound Form Of Merb Mutant C160s, The Organomercurial Lyase Involved In A Bacterial Mercury Res

Crystal Structure Of Merb Complexed With Mercury

alkylmercury lyase MerB [Salmonella enterica subsp. enterica serovar Typhimurium]

alkylmercury lyase, partial [Acinetobacter nosocomialis 28F]

Alkylmercury lyase [Salmonella enterica subsp. enterica serovar Typhimurium]

organomercurial lyase [Escherichia coli]

alkylmercury lyase, partial [Escherichia coli]

MULTISPECIES: alkylmercury lyase [Gammaproteobacteria]

MULTISPECIES: alkylmercury lyase [Enterobacteriaceae]

organomercurial lyase [Salmonella enterica]

RecName: Full=Alkylmercury lyase; AltName: Full=Organomercurial lyase [Serratia marcescens]

RecName: Full=Alkylmercury lyase; AltName: Full=Organomercurial lyase [Klebsiella pneumoniae]

RecName: Full=Alkylmercury lyase; AltName: Full=Organomercurial lyase [Escherichia coli]

RecName: Full=Alkylmercury lyase; AltName: Full=Organomercurial lyase [Sinorhizobium meliloti]

1H, 15N, and 13C resonance assignment of the 23 kDa organomercurial lyase MerB
in the free form

Simulated annealing, with a combination of torsion angle dynamics and cartesian dynamics

Johnson, B.A. and Blevins,
R.A. (1994), J. Biomol. NMR 4, 603-614.

Garrett, D.S., Powers, R.,
Gronenborn, A.M., Clore, G.M. (1991),
J. Magn. Reson. 95, 214-220.