First structure of regulatory domain of skeletal TnC bound with a TnI peptide.

Interactions between sNTnC and the TnI peptide appear to be mostly hydrophobic in nature

regulates skeletal muscle contraction in a calcium dependent fashion

Structure And Interaction Site Of The Regulatory Domain Of Troponin-C When Complexed With The 96-148 Region Of Troponin-I, Nmr, 29 Structures

Limited digital resolution and broad peaks result in the
conservative estimate on chemical shift errors shown above.

McKay, R. T., Pearlstone, J. R., Corson, D. C., Gagne, S. M., Smillie, L. B.,
and Sykes, B. D., "Structure and Interaction Site of the Regulatory Domain
of Troponin-C when Complexed with the 96-148 Region of Troponin-I,"
Biochemistry 37, 12419-12430 (1998).

Structure and interaction site of the regulatory domain of troponin-C when complexed with the 96-148 region of troponin-I.

The NMRPipe system is a UNIX software environment of processing, graphics, and
analysis tools designed to meet current routine and research-oriented
multidimensional processing requirements, and to anticipate and accommodate
future demands and developments. The system is based on UNIX pipes, which allow
programs running simultaneously to exchange streams of data under user control.
In an NMRPipe processing scheme, a stream of spectral data flows through a
pipeline of processing programs, each of which performs one component of the
overall scheme, such as Fourier transformation or linear prediction. Complete
multidimensional processing schemes are constructed as simple UNIX shell
scripts. The processing modules themselves maintain and exploit accurate
records of data sizes, detection modes, and calibration information in all
dimensions, so that schemes can be constructed without the need to explicitly
define or anticipate data sizes or storage details of real and imaginary
channels during processing. The asynchronous pipeline scheme provides other
substantial advantages, including high flexibility, favorable processing
speeds, choice of both all-in-memory and disk-bound processing, easy adaptation
to different data formats, simpler software development and maintenance, and
the ability to distribute processing tasks on multi-CPU computers and computer
networks.

Delaglio, F, Grzesiek, S., Vuister, G.W., Zhu, G., Pfeifer, J.,
and Bax, A. (1995) J. Biomol. NMR 6, 277-293

NMRPipe: a multidimensional spectral processing system based on UNIX pipes.

Garrett, D.S., Powers, R., Gronenborn, A.M.,
and Clore, G.M. (1991) J. Magn. Reson. 95, 214-220

Journal of magnetic resonance (San Diego, Calif. : 1997)
A short recollection on the paper entitled "A common sense approach to peak picking in two-, three-, and four-dimensional spectra using automatic computer analysis of contour diagrams" by D.S. Garrett, R. Powers, A.M. Gronenborn, and G.M. Clore [J. Magn. Reson. 95 (1991) 214-220].

Incorporatin of different NMR sensitive isotopes changes the molecular weight.
(e.g. 2H, 13C, or 15N)

The molecular mass is around 18000 Da.

rabbit skeletal troponin I peptide residues 96-148

X-Ray Crystallographic Study Of Calcium-Saturated N- Terminal Domain Of Troponin C

Structure And Interaction Site Of The Regulatory Domain Of Troponin-C When Complexed With The 96-148 Region Of Troponin-I, Nmr,

Structure Of A Rhodamine-Labeled N-Domain Troponin C Mutant (Ca2+ Saturated) In Complex With Skeletal Troponin I 115- 131

Solution Structure Of Apo N-Domain Of Troponin C, Nmr, 40 Structures

Calcium-Bound E41a Mutant Of The N-Domain Of Chicken Troponin C, Nmr, 40 Structures

Structures Of The Apo And Calcium Troponin-C Regulatory Domains: The Muscle Contraction Switch

Solution Structure Of The Tr1c Fragment Of Skeletal Muscle Troponin-C

N-Domain Of Troponin C From Chicken Skeletal Muscle, Nmr, Minimized Average Structure

Acyl-coenzyme A thioesterase 8 [Chelonia mydas]

Troponin C, skeletal muscle, partial [Chaetura pelagica]

PREDICTED: troponin C, skeletal muscle [Chelonia mydas]

PREDICTED: troponin C, skeletal muscle [Pygoscelis adeliae]

PREDICTED: troponin C, skeletal muscle, partial [Fulmarus glacialis]

PREDICTED: troponin C, skeletal muscle, partial [Cariama cristata]

PREDICTED: troponin C, skeletal muscle [Chaetura pelagica]

Structure and Interaction Site of the Regulatory Domain of Troponin-C when
Complexed with the 96-148 Region of Troponin-I

Full details can be found in the publication.