Proceedings of the National Academy of Sciences of the United States of America
Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.

Calmodulin mutant - F141L apo-form Unstructured C-domain

580 uM [U-99% 13C; U-99% 15N] Calmodulin, 2 mM HEPES, 10 mM potassium chloride,
10 mM EDTA, 2 mM sodium azide, 95% H2O/5% D2O