Crystal structure of PKC alpha in complex with NVP-AEB071

dodecyl 2-(trimethylammonio)ethyl phosphate

dodecyl 2-(trimethylazaniumyl)ethyl phosphate

The C-terminal V5 domain of Protein Kinase Cα is intrinsically disordered, with propensity to associate with a membrane mimetic.

Residue 673 (HSL) is a non-standard Homoserine-lactone that resulted from CNBr cleavage at Methionine residue

Crystal Structure Of Human Protein Kinase C Alpha In Complex With Compound 28 ((r)-6-((3s,4s)-1,3-dimethyl-piperidin-4-yl)-7-(2

protein kinase C alpha type [Homo sapiens]

protein kinase C, alpha [synthetic construct]

protein kinase C alpha type [Rattus norvegicus]

protein kinase C alpha type [Macaca mulatta]

protein kinase C alpha type [Mus musculus]

protein kinase C alpha type [Bos taurus]

RecName: Full=Protein kinase C alpha type; Short=PKC-A; Short=PKC-alpha

In order to accommodate heterologous expression, the DNA sequence which encodes
the amino acid sequence of V5 domain was codon optimized base on the codon usage
of E. coli. The input amino acid sequence of V5 domain is completely identical
among Homo sapiens, Mus musculus and Rattus norvegicus.

V5 domain from Protein Kinase C alpha, C619S mutation, in complex with DPC micelles
Solution NMR assignments of V5 domain from Protein Kinase C alpha, in complex with DPC micelles

T638E/S657E V5 domain of Protein Kinase C alpha

T638E/S657E V5 domain of Protein Kinase C alpha, in complex with DPC micelles

Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax