Mutational tipping points for switching protein folds and functions.

Nmr Structures Of Ga95 And Gb95, Two Designed Proteins With 95% Sequence Identity But Different Folds And Functions

with a Z axis gradient 1H/13C/15N triple resonance cryoprobe

Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax

Laskowski, MacArthur, Smith, Jones, Hutchinson, Morris, Moss and Thornton

Brunger, Adams, Clore, Gros, Nilges and Read