Structural mechanism of transcriptional autorepression of the Escherichia coli RelB/RelE antitoxin/toxin module.

It is the N-terminal 1-50 residues from a 79 residues full-length protein.

Residues 1-3 represent a non-native affinity tag.
This is a DNA binding domain of a antitoxin protein.

Structure Of The Dbd Domain Of E. Coli Antitoxin Relb

Crystal Structure Of The Intact E. Coli Relbe Toxin-Antitoxin Complex

bifunctional antitoxin of the RelE-RelB toxin-antitoxin system and transcriptional repressor [Escherichia coli str. K12 substr.

bifunctional antitoxin of the RelE-RelB toxin-antitoxin system/transcriptional repressor [Escherichia coli O26:H11 str. 11368]

bifunctional antitoxin/transcriptional repressorRelB [Escherichia coli DH1]

antitoxin/transcriptional repressor [Plautia stali symbiont]

unnamed protein product [Escherichia coli]

bifunctional antitoxin of the RelE-RelB toxin-antitoxin system and transcriptional repressor; Qin prophage [Escherichia coli IA

antitoxin of the RelE-RelB toxin-antitoxin system and transcriptional repressor of relBEF [Escherichia coli 042]

addiction module antitoxin, RelB/DinJ family [Enterobacter cloacae subsp. cloacae NCTC 9394]

Negative regulator of translation [Salmonella enterica subsp. enterica serovar Senftenberg str. SS209]

antitoxin of the RelE-RelB toxin-antitoxin syste; transcriptional repressor [Escherichia coli str. K-12 substr. MG1655]

negative regulator of translation [Shigella flexneri 2a str. 301]

negative regulator of translation [Shigella flexneri 2a str. 2457T]

translation negative regulator [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]

negative regulator of translation [Shigella flexneri 5 str. 8401]

bifunctional antitoxin/transcriptional repressor RelB [Shigella flexneri 2a str. 301]

MULTISPECIES: transcriptional regulator [Enterobacteriaceae]

MULTISPECIES: antitoxin RelB [Proteobacteria]

The structure was determined using a combination of NOE and residual dipolar coupling data.

Brunger, Adams, Clore, Gros, Nilges and Read