Chemical shift reference of 1H was based on the proton of water (4.784ppm at
298K) and then those of 15N and 13C were calculated based on their gyromagnetic
ratios.

A POU-A related region dictates DNA binding specificity of LFB1/HNF1 by orienting the two XL-homeodomains in the dimer.

Solution Structure Of The Homeobox Domain Of Hepatocyte Nuclear Factor 1-Beta (Hnf-1beta)

Hepatocyte Nuclear Factor 1b Bound To Dna: Mody5 Gene Product

hepatic nuclear factor 1-beta long form [Mus musculus]

hepatic nuclear factor 1-beta short form [Mus musculus]

variant hepatic nuclear factor 1 (vHNF1) [Rattus norvegicus]

variant hepatic nuclear factor 1 (vHNF1) [Homo sapiens]

varient hepatic nuclear factor 1 [Homo sapiens]

hepatocyte nuclear factor 1-beta [Homo sapiens]

hepatocyte nuclear factor 1-beta isoform 1 [Homo sapiens]

hepatocyte nuclear factor 1-beta [Pongo abelii]

hepatocyte nuclear factor 1-beta isoform 2 [Homo sapiens]

hepatocyte nuclear factor 1-beta [Bos taurus]

hepatocyte nuclear factor 1-beta [Macaca mulatta]

RecName: Full=Hepatocyte nuclear factor 1-beta-A; Short=HNF-1-beta-A; Short=HNF-1B-A; AltName: Full=Hepatocyte nuclear factor 1

RecName: Full=Hepatocyte nuclear factor 1-beta; Short=HNF-1-beta; Short=HNF-1B; AltName: Full=Transcription factor 2; Short=TCF

RecName: Full=Hepatocyte nuclear factor 1-beta; Short=HNF-1-beta; Short=HNF-1B; AltName: Full=Homeoprotein LFB3; AltName: Full=

RecName: Full=Hepatocyte nuclear factor 1-beta; Short=HNF-1-beta; Short=HNF-1B; AltName: Full=FPC-binding protein; Short=FPCB;

TPA: HNF1 homeobox B isoform 1 [Bos taurus]

TPA: HNF1 homeobox B isoform 2 [Bos taurus]

Solution structure of the homeobox domain of Hepatocyte nuclear factor 1-beta
(HNF-1beta)

torsion angle dynamics, restrained molecular dynamics

Protein Research Group, RIKEN Genomic Sciences Center

Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax