data_27670 ####################### # Entry information # ####################### save_entry_information _Entry.Sf_category entry_information _Entry.Sf_framecode entry_information _Entry.ID 27670 _Entry.Title ; HuR GGS ; _Entry.Type macromolecule _Entry.Version_type original _Entry.Submission_date 2018-10-30 _Entry.Accession_date 2018-10-30 _Entry.Last_release_date 2018-10-31 _Entry.Original_release_date 2018-10-31 _Entry.Origination author _Entry.Format_name . _Entry.NMR_STAR_version 3.2.0.16 _Entry.Original_NMR_STAR_version 3.1 _Entry.Experimental_method NMR _Entry.Experimental_method_subtype solution _Entry.Source_data_format . _Entry.Source_data_format_version . _Entry.Generated_software_name . _Entry.Generated_software_version . _Entry.Generated_software_ID . _Entry.Generated_software_label . _Entry.Generated_date . _Entry.DOI . _Entry.UUID . _Entry.Related_coordinate_file_name . _Entry.Details 'Amide chemical shifts of full-length human HuR with linker region (186-239) replaced with 18 GGS repeats.' _Entry.BMRB_internal_directory_name . loop_ _Entry_author.Ordinal _Entry_author.Given_name _Entry_author.Family_name _Entry_author.First_initial _Entry_author.Middle_initials _Entry_author.Family_title _Entry_author.ORCID _Entry_author.Entry_ID 1 Marta Pabis . . . . 27670 2 Grzegorz Popowicz . . . . 27670 3 Andreas Schlundt . . . . 27670 4 Michael Sattler . . . . 27670 stop_ loop_ _Entry_src.ID _Entry_src.Project_name _Entry_src.Organization_full_name _Entry_src.Organization_initials _Entry_src.Entry_ID 1 . 'Technical University Munich, Chair for Biomolecular NMR Spectroscopy' . 27670 stop_ loop_ _Data_set.Type _Data_set.Count _Data_set.Entry_ID assigned_chemical_shifts 1 27670 stop_ loop_ _Datum.Type _Datum.Count _Datum.Entry_ID '15N chemical shifts' 220 27670 '1H chemical shifts' 220 27670 stop_ loop_ _Release.Release_number _Release.Format_type _Release.Format_version _Release.Date _Release.Submission_date _Release.Type _Release.Author _Release.Detail _Release.Entry_ID 2 . . 2019-02-15 2018-10-30 update BMRB 'update entry citation' 27670 1 . . 2018-11-14 2018-10-30 original author 'original release' 27670 stop_ save_ ############### # Citations # ############### save_entry_citation _Citation.Sf_category citations _Citation.Sf_framecode entry_citation _Citation.Entry_ID 27670 _Citation.ID 1 _Citation.Class 'entry citation' _Citation.CAS_abstract_code . _Citation.MEDLINE_UI_code . _Citation.DOI . _Citation.PubMed_ID 30418581 _Citation.Full_citation . _Citation.Title ; HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs. ; _Citation.Status published _Citation.Type journal _Citation.Journal_abbrev 'Nucleic Acids Res.' _Citation.Journal_name_full 'Nucleic acids research' _Citation.Journal_volume 47 _Citation.Journal_issue 2 _Citation.Journal_ASTM . _Citation.Journal_ISSN 1362-4962 _Citation.Journal_CSD . _Citation.Book_title . _Citation.Book_chapter_title . _Citation.Book_volume . _Citation.Book_series . _Citation.Book_publisher . _Citation.Book_publisher_city . _Citation.Book_ISBN . _Citation.Conference_title . _Citation.Conference_site . _Citation.Conference_state_province . _Citation.Conference_country . _Citation.Conference_start_date . _Citation.Conference_end_date . _Citation.Conference_abstract_number . _Citation.Thesis_institution . _Citation.Thesis_institution_city . _Citation.Thesis_institution_country . _Citation.WWW_URL . _Citation.Page_first 1011 _Citation.Page_last 1029 _Citation.Year 2019 _Citation.Details . loop_ _Citation_author.Ordinal _Citation_author.Given_name _Citation_author.Family_name _Citation_author.First_initial _Citation_author.Middle_initials _Citation_author.Family_title _Citation_author.ORCID _Citation_author.Entry_ID _Citation_author.Citation_ID 1 Marta Pabis . . . . 27670 1 2 Grzegorz Popowicz . . . . 27670 1 3 Ralf Stehle . . . . 27670 1 4 David Fernandez-Ramos . . . . 27670 1 5 Sam Asami . . . . 27670 1 6 Lisa Warner . . . . 27670 1 7 Sofia Garcia-Maurino . . . . 27670 1 8 Andreas Schlundt . . . . 27670 1 9 Maria Martinez-Chantar . . . . 27670 1 10 Irene Diaz-Moreno . . . . 27670 1 11 Michael Sattler . . . . 27670 1 stop_ loop_ _Citation_keyword.Keyword _Citation_keyword.Entry_ID _Citation_keyword.Citation_ID 'Human antigen R protein' 27670 1 'Integrated structural biology' 27670 1 'Multi-domain RNA binding protein' 27670 1 'mRNA stability' 27670 1 stop_ save_ ############################################# # Molecular system (assembly) description # ############################################# save_assembly _Assembly.Sf_category assembly _Assembly.Sf_framecode assembly _Assembly.Entry_ID 27670 _Assembly.ID 1 _Assembly.Name 'HuR GGS' _Assembly.BMRB_code . _Assembly.Number_of_components 1 _Assembly.Organic_ligands . _Assembly.Metal_ions . _Assembly.Non_standard_bonds no _Assembly.Ambiguous_conformational_states . _Assembly.Ambiguous_chem_comp_sites . _Assembly.Molecules_in_chemical_exchange . _Assembly.Paramagnetic no _Assembly.Thiol_state . _Assembly.Molecular_mass 34020.76 _Assembly.Enzyme_commission_number . _Assembly.Details . _Assembly.DB_query_date . _Assembly.DB_query_revised_last_date . loop_ _Entity_assembly.ID _Entity_assembly.Entity_assembly_name _Entity_assembly.Entity_ID _Entity_assembly.Entity_label _Entity_assembly.Asym_ID _Entity_assembly.PDB_chain_ID _Entity_assembly.Experimental_data_reported _Entity_assembly.Physical_state _Entity_assembly.Conformational_isomer _Entity_assembly.Chemical_exchange_state _Entity_assembly.Magnetic_equivalence_group_code _Entity_assembly.Role _Entity_assembly.Details _Entity_assembly.Entry_ID _Entity_assembly.Assembly_ID 1 'HuR GGS' 1 $HuR_GGS A . yes native no no . . . 27670 1 stop_ loop_ _Assembly_bio_function.Biological_function _Assembly_bio_function.Entry_ID _Assembly_bio_function.Assembly_ID 'mRNA binding' 27670 1 stop_ save_ #################################### # Biological polymers and ligands # #################################### save_HuR_GGS _Entity.Sf_category entity _Entity.Sf_framecode HuR_GGS _Entity.Entry_ID 27670 _Entity.ID 1 _Entity.BMRB_code . _Entity.Name HuR_GGS _Entity.Type polymer _Entity.Polymer_common_type . _Entity.Polymer_type polypeptide(L) _Entity.Polymer_type_details . _Entity.Polymer_strand_ID . _Entity.Polymer_seq_one_letter_code_can . _Entity.Polymer_seq_one_letter_code ; GAMASNGYEDHMAEDCRGDI GRTNLIVNYLPQNMTQDELR SLFSSIGEVESAKLIRDKVA GHSLGYGFVNYVTAKDAERA INTLNGLRLQSKTIKVSYAR PSSEVIKDANLYISGLPRTM TQKDVEDMFSRFGRIINSRV LVDQTTGLSRGVAFIRFDKR SEAEEAITSFNGHKPPGSSE PITVKFAATGGSGGSGGSGG SGGSGGSGGSGGSGGSGGSG GSGGSGGSGGSGGSGGSGGS GGASSGWCIFIYNLGQDADE GILWQMFGPFGAVTNVKVIR DFNTNKCKGFGFVTMTNYEE AAMAIASLNGYRLGDKILQV SFKTNKSHK ; _Entity.Target_identifier . _Entity.Polymer_author_defined_seq Ser2-Lys326 _Entity.Polymer_author_seq_details 'GAMA is from cloning' _Entity.Ambiguous_conformational_states no _Entity.Ambiguous_chem_comp_sites no _Entity.Nstd_monomer no _Entity.Nstd_chirality no _Entity.Nstd_linkage no _Entity.Nonpolymer_comp_ID . _Entity.Nonpolymer_comp_label . _Entity.Number_of_monomers 329 _Entity.Number_of_nonpolymer_components . _Entity.Paramagnetic no _Entity.Thiol_state 'all free' _Entity.Src_method . _Entity.Parent_entity_ID . _Entity.Fragment . _Entity.Mutation . _Entity.EC_number . _Entity.Calc_isoelectric_point . _Entity.Formula_weight 34020.76 _Entity.Formula_weight_exptl . _Entity.Formula_weight_exptl_meth . _Entity.Details . _Entity.DB_query_date . _Entity.DB_query_revised_last_date . loop_ _Entity_biological_function.Biological_function _Entity_biological_function.Entry_ID _Entity_biological_function.Entity_ID 'mRNA binding' 27670 1 stop_ loop_ _Entity_comp_index.ID _Entity_comp_index.Auth_seq_ID _Entity_comp_index.Comp_ID _Entity_comp_index.Comp_label _Entity_comp_index.Entry_ID _Entity_comp_index.Entity_ID 1 -2 GLY . 27670 1 2 -1 ALA . 27670 1 3 0 MET . 27670 1 4 1 ALA . 27670 1 5 2 SER . 27670 1 6 3 ASN . 27670 1 7 4 GLY . 27670 1 8 5 TYR . 27670 1 9 6 GLU . 27670 1 10 7 ASP . 27670 1 11 8 HIS . 27670 1 12 9 MET . 27670 1 13 10 ALA . 27670 1 14 11 GLU . 27670 1 15 12 ASP . 27670 1 16 13 CYS . 27670 1 17 14 ARG . 27670 1 18 15 GLY . 27670 1 19 16 ASP . 27670 1 20 17 ILE . 27670 1 21 18 GLY . 27670 1 22 19 ARG . 27670 1 23 20 THR . 27670 1 24 21 ASN . 27670 1 25 22 LEU . 27670 1 26 23 ILE . 27670 1 27 24 VAL . 27670 1 28 25 ASN . 27670 1 29 26 TYR . 27670 1 30 27 LEU . 27670 1 31 28 PRO . 27670 1 32 29 GLN . 27670 1 33 30 ASN . 27670 1 34 31 MET . 27670 1 35 32 THR . 27670 1 36 33 GLN . 27670 1 37 34 ASP . 27670 1 38 35 GLU . 27670 1 39 36 LEU . 27670 1 40 37 ARG . 27670 1 41 38 SER . 27670 1 42 39 LEU . 27670 1 43 40 PHE . 27670 1 44 41 SER . 27670 1 45 42 SER . 27670 1 46 43 ILE . 27670 1 47 44 GLY . 27670 1 48 45 GLU . 27670 1 49 46 VAL . 27670 1 50 47 GLU . 27670 1 51 48 SER . 27670 1 52 49 ALA . 27670 1 53 50 LYS . 27670 1 54 51 LEU . 27670 1 55 52 ILE . 27670 1 56 53 ARG . 27670 1 57 54 ASP . 27670 1 58 55 LYS . 27670 1 59 56 VAL . 27670 1 60 57 ALA . 27670 1 61 58 GLY . 27670 1 62 59 HIS . 27670 1 63 60 SER . 27670 1 64 61 LEU . 27670 1 65 62 GLY . 27670 1 66 63 TYR . 27670 1 67 64 GLY . 27670 1 68 65 PHE . 27670 1 69 66 VAL . 27670 1 70 67 ASN . 27670 1 71 68 TYR . 27670 1 72 69 VAL . 27670 1 73 70 THR . 27670 1 74 71 ALA . 27670 1 75 72 LYS . 27670 1 76 73 ASP . 27670 1 77 74 ALA . 27670 1 78 75 GLU . 27670 1 79 76 ARG . 27670 1 80 77 ALA . 27670 1 81 78 ILE . 27670 1 82 79 ASN . 27670 1 83 80 THR . 27670 1 84 81 LEU . 27670 1 85 82 ASN . 27670 1 86 83 GLY . 27670 1 87 84 LEU . 27670 1 88 85 ARG . 27670 1 89 86 LEU . 27670 1 90 87 GLN . 27670 1 91 88 SER . 27670 1 92 89 LYS . 27670 1 93 90 THR . 27670 1 94 91 ILE . 27670 1 95 92 LYS . 27670 1 96 93 VAL . 27670 1 97 94 SER . 27670 1 98 95 TYR . 27670 1 99 96 ALA . 27670 1 100 97 ARG . 27670 1 101 98 PRO . 27670 1 102 99 SER . 27670 1 103 100 SER . 27670 1 104 101 GLU . 27670 1 105 102 VAL . 27670 1 106 103 ILE . 27670 1 107 104 LYS . 27670 1 108 105 ASP . 27670 1 109 106 ALA . 27670 1 110 107 ASN . 27670 1 111 108 LEU . 27670 1 112 109 TYR . 27670 1 113 110 ILE . 27670 1 114 111 SER . 27670 1 115 112 GLY . 27670 1 116 113 LEU . 27670 1 117 114 PRO . 27670 1 118 115 ARG . 27670 1 119 116 THR . 27670 1 120 117 MET . 27670 1 121 118 THR . 27670 1 122 119 GLN . 27670 1 123 120 LYS . 27670 1 124 121 ASP . 27670 1 125 122 VAL . 27670 1 126 123 GLU . 27670 1 127 124 ASP . 27670 1 128 125 MET . 27670 1 129 126 PHE . 27670 1 130 127 SER . 27670 1 131 128 ARG . 27670 1 132 129 PHE . 27670 1 133 130 GLY . 27670 1 134 131 ARG . 27670 1 135 132 ILE . 27670 1 136 133 ILE . 27670 1 137 134 ASN . 27670 1 138 135 SER . 27670 1 139 136 ARG . 27670 1 140 137 VAL . 27670 1 141 138 LEU . 27670 1 142 139 VAL . 27670 1 143 140 ASP . 27670 1 144 141 GLN . 27670 1 145 142 THR . 27670 1 146 143 THR . 27670 1 147 144 GLY . 27670 1 148 145 LEU . 27670 1 149 146 SER . 27670 1 150 147 ARG . 27670 1 151 148 GLY . 27670 1 152 149 VAL . 27670 1 153 150 ALA . 27670 1 154 151 PHE . 27670 1 155 152 ILE . 27670 1 156 153 ARG . 27670 1 157 154 PHE . 27670 1 158 155 ASP . 27670 1 159 156 LYS . 27670 1 160 157 ARG . 27670 1 161 158 SER . 27670 1 162 159 GLU . 27670 1 163 160 ALA . 27670 1 164 161 GLU . 27670 1 165 162 GLU . 27670 1 166 163 ALA . 27670 1 167 164 ILE . 27670 1 168 165 THR . 27670 1 169 166 SER . 27670 1 170 167 PHE . 27670 1 171 168 ASN . 27670 1 172 169 GLY . 27670 1 173 170 HIS . 27670 1 174 171 LYS . 27670 1 175 172 PRO . 27670 1 176 173 PRO . 27670 1 177 174 GLY . 27670 1 178 175 SER . 27670 1 179 176 SER . 27670 1 180 177 GLU . 27670 1 181 178 PRO . 27670 1 182 179 ILE . 27670 1 183 180 THR . 27670 1 184 181 VAL . 27670 1 185 182 LYS . 27670 1 186 183 PHE . 27670 1 187 184 ALA . 27670 1 188 185 ALA . 27670 1 189 186 THR . 27670 1 190 187 GLY . 27670 1 191 188 GLY . 27670 1 192 189 SER . 27670 1 193 190 GLY . 27670 1 194 191 GLY . 27670 1 195 192 SER . 27670 1 196 193 GLY . 27670 1 197 194 GLY . 27670 1 198 195 SER . 27670 1 199 196 GLY . 27670 1 200 197 GLY . 27670 1 201 198 SER . 27670 1 202 199 GLY . 27670 1 203 200 GLY . 27670 1 204 201 SER . 27670 1 205 202 GLY . 27670 1 206 203 GLY . 27670 1 207 204 SER . 27670 1 208 205 GLY . 27670 1 209 206 GLY . 27670 1 210 207 SER . 27670 1 211 208 GLY . 27670 1 212 209 GLY . 27670 1 213 210 SER . 27670 1 214 211 GLY . 27670 1 215 212 GLY . 27670 1 216 213 SER . 27670 1 217 214 GLY . 27670 1 218 215 GLY . 27670 1 219 216 SER . 27670 1 220 217 GLY . 27670 1 221 218 GLY . 27670 1 222 219 SER . 27670 1 223 220 GLY . 27670 1 224 221 GLY . 27670 1 225 222 SER . 27670 1 226 223 GLY . 27670 1 227 224 GLY . 27670 1 228 225 SER . 27670 1 229 226 GLY . 27670 1 230 227 GLY . 27670 1 231 228 SER . 27670 1 232 229 GLY . 27670 1 233 230 GLY . 27670 1 234 231 SER . 27670 1 235 232 GLY . 27670 1 236 233 GLY . 27670 1 237 234 SER . 27670 1 238 235 GLY . 27670 1 239 236 GLY . 27670 1 240 237 SER . 27670 1 241 238 GLY . 27670 1 242 239 GLY . 27670 1 243 240 ALA . 27670 1 244 241 SER . 27670 1 245 242 SER . 27670 1 246 243 GLY . 27670 1 247 244 TRP . 27670 1 248 245 CYS . 27670 1 249 246 ILE . 27670 1 250 247 PHE . 27670 1 251 248 ILE . 27670 1 252 249 TYR . 27670 1 253 250 ASN . 27670 1 254 251 LEU . 27670 1 255 252 GLY . 27670 1 256 253 GLN . 27670 1 257 254 ASP . 27670 1 258 255 ALA . 27670 1 259 256 ASP . 27670 1 260 257 GLU . 27670 1 261 258 GLY . 27670 1 262 259 ILE . 27670 1 263 260 LEU . 27670 1 264 261 TRP . 27670 1 265 262 GLN . 27670 1 266 263 MET . 27670 1 267 264 PHE . 27670 1 268 265 GLY . 27670 1 269 266 PRO . 27670 1 270 267 PHE . 27670 1 271 268 GLY . 27670 1 272 269 ALA . 27670 1 273 270 VAL . 27670 1 274 271 THR . 27670 1 275 272 ASN . 27670 1 276 273 VAL . 27670 1 277 274 LYS . 27670 1 278 275 VAL . 27670 1 279 276 ILE . 27670 1 280 277 ARG . 27670 1 281 278 ASP . 27670 1 282 279 PHE . 27670 1 283 280 ASN . 27670 1 284 281 THR . 27670 1 285 282 ASN . 27670 1 286 283 LYS . 27670 1 287 284 CYS . 27670 1 288 285 LYS . 27670 1 289 286 GLY . 27670 1 290 287 PHE . 27670 1 291 288 GLY . 27670 1 292 289 PHE . 27670 1 293 290 VAL . 27670 1 294 291 THR . 27670 1 295 292 MET . 27670 1 296 293 THR . 27670 1 297 294 ASN . 27670 1 298 295 TYR . 27670 1 299 296 GLU . 27670 1 300 297 GLU . 27670 1 301 298 ALA . 27670 1 302 299 ALA . 27670 1 303 300 MET . 27670 1 304 301 ALA . 27670 1 305 302 ILE . 27670 1 306 303 ALA . 27670 1 307 304 SER . 27670 1 308 305 LEU . 27670 1 309 306 ASN . 27670 1 310 307 GLY . 27670 1 311 308 TYR . 27670 1 312 309 ARG . 27670 1 313 310 LEU . 27670 1 314 311 GLY . 27670 1 315 312 ASP . 27670 1 316 313 LYS . 27670 1 317 314 ILE . 27670 1 318 315 LEU . 27670 1 319 316 GLN . 27670 1 320 317 VAL . 27670 1 321 318 SER . 27670 1 322 319 PHE . 27670 1 323 320 LYS . 27670 1 324 321 THR . 27670 1 325 322 ASN . 27670 1 326 323 LYS . 27670 1 327 324 SER . 27670 1 328 325 HIS . 27670 1 329 326 LYS . 27670 1 stop_ loop_ _Entity_poly_seq.Hetero _Entity_poly_seq.Mon_ID _Entity_poly_seq.Num _Entity_poly_seq.Comp_index_ID _Entity_poly_seq.Entry_ID _Entity_poly_seq.Entity_ID . GLY 1 1 27670 1 . ALA 2 2 27670 1 . MET 3 3 27670 1 . ALA 4 4 27670 1 . SER 5 5 27670 1 . ASN 6 6 27670 1 . GLY 7 7 27670 1 . TYR 8 8 27670 1 . GLU 9 9 27670 1 . ASP 10 10 27670 1 . HIS 11 11 27670 1 . MET 12 12 27670 1 . ALA 13 13 27670 1 . GLU 14 14 27670 1 . ASP 15 15 27670 1 . CYS 16 16 27670 1 . ARG 17 17 27670 1 . GLY 18 18 27670 1 . ASP 19 19 27670 1 . ILE 20 20 27670 1 . GLY 21 21 27670 1 . ARG 22 22 27670 1 . THR 23 23 27670 1 . ASN 24 24 27670 1 . LEU 25 25 27670 1 . ILE 26 26 27670 1 . VAL 27 27 27670 1 . ASN 28 28 27670 1 . TYR 29 29 27670 1 . LEU 30 30 27670 1 . PRO 31 31 27670 1 . GLN 32 32 27670 1 . ASN 33 33 27670 1 . MET 34 34 27670 1 . THR 35 35 27670 1 . GLN 36 36 27670 1 . ASP 37 37 27670 1 . GLU 38 38 27670 1 . LEU 39 39 27670 1 . ARG 40 40 27670 1 . SER 41 41 27670 1 . LEU 42 42 27670 1 . PHE 43 43 27670 1 . SER 44 44 27670 1 . SER 45 45 27670 1 . ILE 46 46 27670 1 . GLY 47 47 27670 1 . GLU 48 48 27670 1 . VAL 49 49 27670 1 . GLU 50 50 27670 1 . SER 51 51 27670 1 . ALA 52 52 27670 1 . LYS 53 53 27670 1 . LEU 54 54 27670 1 . ILE 55 55 27670 1 . ARG 56 56 27670 1 . ASP 57 57 27670 1 . LYS 58 58 27670 1 . VAL 59 59 27670 1 . ALA 60 60 27670 1 . GLY 61 61 27670 1 . HIS 62 62 27670 1 . SER 63 63 27670 1 . LEU 64 64 27670 1 . GLY 65 65 27670 1 . TYR 66 66 27670 1 . GLY 67 67 27670 1 . PHE 68 68 27670 1 . VAL 69 69 27670 1 . ASN 70 70 27670 1 . TYR 71 71 27670 1 . VAL 72 72 27670 1 . THR 73 73 27670 1 . ALA 74 74 27670 1 . LYS 75 75 27670 1 . ASP 76 76 27670 1 . ALA 77 77 27670 1 . GLU 78 78 27670 1 . ARG 79 79 27670 1 . ALA 80 80 27670 1 . ILE 81 81 27670 1 . ASN 82 82 27670 1 . THR 83 83 27670 1 . LEU 84 84 27670 1 . ASN 85 85 27670 1 . GLY 86 86 27670 1 . LEU 87 87 27670 1 . ARG 88 88 27670 1 . LEU 89 89 27670 1 . GLN 90 90 27670 1 . SER 91 91 27670 1 . LYS 92 92 27670 1 . THR 93 93 27670 1 . ILE 94 94 27670 1 . LYS 95 95 27670 1 . VAL 96 96 27670 1 . SER 97 97 27670 1 . TYR 98 98 27670 1 . ALA 99 99 27670 1 . ARG 100 100 27670 1 . PRO 101 101 27670 1 . SER 102 102 27670 1 . SER 103 103 27670 1 . GLU 104 104 27670 1 . VAL 105 105 27670 1 . ILE 106 106 27670 1 . LYS 107 107 27670 1 . ASP 108 108 27670 1 . ALA 109 109 27670 1 . ASN 110 110 27670 1 . LEU 111 111 27670 1 . TYR 112 112 27670 1 . ILE 113 113 27670 1 . SER 114 114 27670 1 . GLY 115 115 27670 1 . LEU 116 116 27670 1 . PRO 117 117 27670 1 . ARG 118 118 27670 1 . THR 119 119 27670 1 . MET 120 120 27670 1 . THR 121 121 27670 1 . GLN 122 122 27670 1 . LYS 123 123 27670 1 . ASP 124 124 27670 1 . VAL 125 125 27670 1 . GLU 126 126 27670 1 . ASP 127 127 27670 1 . MET 128 128 27670 1 . PHE 129 129 27670 1 . SER 130 130 27670 1 . ARG 131 131 27670 1 . PHE 132 132 27670 1 . GLY 133 133 27670 1 . ARG 134 134 27670 1 . ILE 135 135 27670 1 . ILE 136 136 27670 1 . ASN 137 137 27670 1 . SER 138 138 27670 1 . ARG 139 139 27670 1 . VAL 140 140 27670 1 . LEU 141 141 27670 1 . VAL 142 142 27670 1 . ASP 143 143 27670 1 . GLN 144 144 27670 1 . THR 145 145 27670 1 . THR 146 146 27670 1 . GLY 147 147 27670 1 . LEU 148 148 27670 1 . SER 149 149 27670 1 . ARG 150 150 27670 1 . GLY 151 151 27670 1 . VAL 152 152 27670 1 . ALA 153 153 27670 1 . PHE 154 154 27670 1 . ILE 155 155 27670 1 . ARG 156 156 27670 1 . PHE 157 157 27670 1 . ASP 158 158 27670 1 . LYS 159 159 27670 1 . ARG 160 160 27670 1 . SER 161 161 27670 1 . GLU 162 162 27670 1 . ALA 163 163 27670 1 . GLU 164 164 27670 1 . GLU 165 165 27670 1 . ALA 166 166 27670 1 . ILE 167 167 27670 1 . THR 168 168 27670 1 . SER 169 169 27670 1 . PHE 170 170 27670 1 . ASN 171 171 27670 1 . GLY 172 172 27670 1 . HIS 173 173 27670 1 . LYS 174 174 27670 1 . PRO 175 175 27670 1 . PRO 176 176 27670 1 . GLY 177 177 27670 1 . SER 178 178 27670 1 . SER 179 179 27670 1 . GLU 180 180 27670 1 . PRO 181 181 27670 1 . ILE 182 182 27670 1 . THR 183 183 27670 1 . VAL 184 184 27670 1 . LYS 185 185 27670 1 . PHE 186 186 27670 1 . ALA 187 187 27670 1 . ALA 188 188 27670 1 . THR 189 189 27670 1 . GLY 190 190 27670 1 . GLY 191 191 27670 1 . SER 192 192 27670 1 . GLY 193 193 27670 1 . GLY 194 194 27670 1 . SER 195 195 27670 1 . GLY 196 196 27670 1 . GLY 197 197 27670 1 . SER 198 198 27670 1 . GLY 199 199 27670 1 . GLY 200 200 27670 1 . SER 201 201 27670 1 . GLY 202 202 27670 1 . GLY 203 203 27670 1 . SER 204 204 27670 1 . GLY 205 205 27670 1 . GLY 206 206 27670 1 . SER 207 207 27670 1 . GLY 208 208 27670 1 . GLY 209 209 27670 1 . SER 210 210 27670 1 . GLY 211 211 27670 1 . GLY 212 212 27670 1 . SER 213 213 27670 1 . GLY 214 214 27670 1 . GLY 215 215 27670 1 . SER 216 216 27670 1 . GLY 217 217 27670 1 . GLY 218 218 27670 1 . SER 219 219 27670 1 . GLY 220 220 27670 1 . GLY 221 221 27670 1 . SER 222 222 27670 1 . GLY 223 223 27670 1 . GLY 224 224 27670 1 . SER 225 225 27670 1 . GLY 226 226 27670 1 . GLY 227 227 27670 1 . SER 228 228 27670 1 . GLY 229 229 27670 1 . GLY 230 230 27670 1 . SER 231 231 27670 1 . GLY 232 232 27670 1 . GLY 233 233 27670 1 . SER 234 234 27670 1 . GLY 235 235 27670 1 . GLY 236 236 27670 1 . SER 237 237 27670 1 . GLY 238 238 27670 1 . GLY 239 239 27670 1 . SER 240 240 27670 1 . GLY 241 241 27670 1 . GLY 242 242 27670 1 . ALA 243 243 27670 1 . SER 244 244 27670 1 . SER 245 245 27670 1 . GLY 246 246 27670 1 . TRP 247 247 27670 1 . CYS 248 248 27670 1 . ILE 249 249 27670 1 . PHE 250 250 27670 1 . ILE 251 251 27670 1 . TYR 252 252 27670 1 . ASN 253 253 27670 1 . LEU 254 254 27670 1 . GLY 255 255 27670 1 . GLN 256 256 27670 1 . ASP 257 257 27670 1 . ALA 258 258 27670 1 . ASP 259 259 27670 1 . GLU 260 260 27670 1 . GLY 261 261 27670 1 . ILE 262 262 27670 1 . LEU 263 263 27670 1 . TRP 264 264 27670 1 . GLN 265 265 27670 1 . MET 266 266 27670 1 . PHE 267 267 27670 1 . GLY 268 268 27670 1 . PRO 269 269 27670 1 . PHE 270 270 27670 1 . GLY 271 271 27670 1 . ALA 272 272 27670 1 . VAL 273 273 27670 1 . THR 274 274 27670 1 . ASN 275 275 27670 1 . VAL 276 276 27670 1 . LYS 277 277 27670 1 . VAL 278 278 27670 1 . ILE 279 279 27670 1 . ARG 280 280 27670 1 . ASP 281 281 27670 1 . PHE 282 282 27670 1 . ASN 283 283 27670 1 . THR 284 284 27670 1 . ASN 285 285 27670 1 . LYS 286 286 27670 1 . CYS 287 287 27670 1 . LYS 288 288 27670 1 . GLY 289 289 27670 1 . PHE 290 290 27670 1 . GLY 291 291 27670 1 . PHE 292 292 27670 1 . VAL 293 293 27670 1 . THR 294 294 27670 1 . MET 295 295 27670 1 . THR 296 296 27670 1 . ASN 297 297 27670 1 . TYR 298 298 27670 1 . GLU 299 299 27670 1 . GLU 300 300 27670 1 . ALA 301 301 27670 1 . ALA 302 302 27670 1 . MET 303 303 27670 1 . ALA 304 304 27670 1 . ILE 305 305 27670 1 . ALA 306 306 27670 1 . SER 307 307 27670 1 . LEU 308 308 27670 1 . ASN 309 309 27670 1 . GLY 310 310 27670 1 . TYR 311 311 27670 1 . ARG 312 312 27670 1 . LEU 313 313 27670 1 . GLY 314 314 27670 1 . ASP 315 315 27670 1 . LYS 316 316 27670 1 . ILE 317 317 27670 1 . LEU 318 318 27670 1 . GLN 319 319 27670 1 . VAL 320 320 27670 1 . SER 321 321 27670 1 . PHE 322 322 27670 1 . LYS 323 323 27670 1 . THR 324 324 27670 1 . ASN 325 325 27670 1 . LYS 326 326 27670 1 . SER 327 327 27670 1 . HIS 328 328 27670 1 . LYS 329 329 27670 1 stop_ save_ #################### # Natural source # #################### save_natural_source _Entity_natural_src_list.Sf_category natural_source _Entity_natural_src_list.Sf_framecode natural_source _Entity_natural_src_list.Entry_ID 27670 _Entity_natural_src_list.ID 1 loop_ _Entity_natural_src.ID _Entity_natural_src.Entity_ID _Entity_natural_src.Entity_label _Entity_natural_src.Entity_chimera_segment_ID _Entity_natural_src.NCBI_taxonomy_ID _Entity_natural_src.Type _Entity_natural_src.Common _Entity_natural_src.Organism_name_scientific _Entity_natural_src.Organism_name_common _Entity_natural_src.Organism_acronym _Entity_natural_src.ICTVdb_decimal_code _Entity_natural_src.Superkingdom _Entity_natural_src.Kingdom _Entity_natural_src.Genus _Entity_natural_src.Species _Entity_natural_src.Strain _Entity_natural_src.Variant _Entity_natural_src.Organ _Entity_natural_src.Tissue _Entity_natural_src.Tissue_fraction _Entity_natural_src.Cell_line _Entity_natural_src.Cell_type _Entity_natural_src.ATCC_number _Entity_natural_src.Organelle _Entity_natural_src.Secretion _Entity_natural_src.Plasmid _Entity_natural_src.Gene_mnemonic _Entity_natural_src.Details _Entity_natural_src.Entry_ID _Entity_natural_src.Entity_natural_src_list_ID 1 1 $HuR_GGS . 9606 organism . 'Homo sapiens' Human . . Eukaryota Metazoa Homo sapiens . . . . . . . . . . . . . 27670 1 stop_ save_ ######################### # Experimental source # ######################### save_experimental_source _Entity_experimental_src_list.Sf_category experimental_source _Entity_experimental_src_list.Sf_framecode experimental_source _Entity_experimental_src_list.Entry_ID 27670 _Entity_experimental_src_list.ID 1 loop_ _Entity_experimental_src.ID _Entity_experimental_src.Entity_ID _Entity_experimental_src.Entity_label _Entity_experimental_src.Entity_chimera_segment_ID _Entity_experimental_src.Production_method _Entity_experimental_src.Host_org_scientific_name _Entity_experimental_src.Host_org_name_common _Entity_experimental_src.Host_org_details _Entity_experimental_src.Host_org_NCBI_taxonomy_ID _Entity_experimental_src.Host_org_genus _Entity_experimental_src.Host_org_species _Entity_experimental_src.Host_org_strain _Entity_experimental_src.Host_org_variant _Entity_experimental_src.Host_org_ATCC_number _Entity_experimental_src.Vector_type _Entity_experimental_src.PDBview_host_org_vector_name _Entity_experimental_src.PDBview_plasmid_name _Entity_experimental_src.Vector_name _Entity_experimental_src.Vector_details _Entity_experimental_src.Vendor_name _Entity_experimental_src.Details _Entity_experimental_src.Entry_ID _Entity_experimental_src.Entity_experimental_src_list_ID 1 1 $HuR_GGS . 'recombinant technology' 'Escherichia coli' . . . Escherichia coli K12 'BL21 (DE3)' . . . . pETM11 . . . 27670 1 stop_ save_ ##################################### # Sample contents and methodology # ##################################### ######################## # Sample description # ######################## save_sample_1 _Sample.Sf_category sample _Sample.Sf_framecode sample_1 _Sample.Entry_ID 27670 _Sample.ID 1 _Sample.Type solution _Sample.Sub_type . _Sample.Details . _Sample.Aggregate_sample_number . _Sample.Solvent_system '95% H2O/5% D2O' _Sample.Preparation_date . _Sample.Preparation_expiration_date . _Sample.Polycrystallization_protocol . _Sample.Single_crystal_protocol . _Sample.Crystal_grow_apparatus . _Sample.Crystal_grow_atmosphere . _Sample.Crystal_grow_details . _Sample.Crystal_grow_method . _Sample.Crystal_grow_method_cit_ID . _Sample.Crystal_grow_pH . _Sample.Crystal_grow_pH_range . _Sample.Crystal_grow_pressure . _Sample.Crystal_grow_pressure_esd . _Sample.Crystal_grow_seeding . _Sample.Crystal_grow_seeding_cit_ID . _Sample.Crystal_grow_temp . _Sample.Crystal_grow_temp_details . _Sample.Crystal_grow_temp_esd . _Sample.Crystal_grow_time . _Sample.Oriented_sample_prep_protocol . _Sample.Lyophilization_cryo_protectant . _Sample.Storage_protocol . loop_ _Sample_component.ID _Sample_component.Mol_common_name _Sample_component.Isotopic_labeling _Sample_component.Assembly_ID _Sample_component.Assembly_label _Sample_component.Entity_ID _Sample_component.Entity_label _Sample_component.Product_ID _Sample_component.Type _Sample_component.Concentration_val _Sample_component.Concentration_val_min _Sample_component.Concentration_val_max _Sample_component.Concentration_val_units _Sample_component.Concentration_val_err _Sample_component.Vendor _Sample_component.Vendor_product_name _Sample_component.Vendor_product_code _Sample_component.Entry_ID _Sample_component.Sample_ID 1 'HuR GGS' [U-15N] . . 1 $HuR_GGS . . 70 . . uM . . . . 27670 1 2 'sodium phosphate' 'natural abundance' . . . . . . 20 . . mM . . . . 27670 1 3 'sodium chloride' 'natural abundance' . . . . . . 200 . . mM . . . . 27670 1 4 DTT 'natural abundance' . . . . . . 5 . . mM . . . . 27670 1 5 EDTA 'natural abundance' . . . . . . 1 . . mM . . . . 27670 1 stop_ save_ ####################### # Sample conditions # ####################### save_sample_conditions_1 _Sample_condition_list.Sf_category sample_conditions _Sample_condition_list.Sf_framecode sample_conditions_1 _Sample_condition_list.Entry_ID 27670 _Sample_condition_list.ID 1 _Sample_condition_list.Details . loop_ _Sample_condition_variable.Type _Sample_condition_variable.Val _Sample_condition_variable.Val_err _Sample_condition_variable.Val_units _Sample_condition_variable.Entry_ID _Sample_condition_variable.Sample_condition_list_ID pH 7.0 . pH 27670 1 pressure 1 . atm 27670 1 temperature 298 . K 27670 1 stop_ save_ ############################ # Computer software used # ############################ save_TOPSPIN _Software.Sf_category software _Software.Sf_framecode TOPSPIN _Software.Entry_ID 27670 _Software.ID 1 _Software.Type . _Software.Name TOPSPIN _Software.Version . _Software.DOI . _Software.Details . loop_ _Vendor.Name _Vendor.Address _Vendor.Electronic_address _Vendor.Entry_ID _Vendor.Software_ID 'Bruker Biospin' . . 27670 1 stop_ loop_ _Task.Task _Task.Entry_ID _Task.Software_ID collection 27670 1 stop_ save_ save_NMRPipe _Software.Sf_category software _Software.Sf_framecode NMRPipe _Software.Entry_ID 27670 _Software.ID 2 _Software.Type . _Software.Name NMRPipe _Software.Version . _Software.DOI . _Software.Details . loop_ _Vendor.Name _Vendor.Address _Vendor.Electronic_address _Vendor.Entry_ID _Vendor.Software_ID 'Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax' . . 27670 2 stop_ loop_ _Task.Task _Task.Entry_ID _Task.Software_ID processing 27670 2 stop_ save_ save_CCPNMR_Analysis _Software.Sf_category software _Software.Sf_framecode CCPNMR_Analysis _Software.Entry_ID 27670 _Software.ID 3 _Software.Type . _Software.Name CCPNMR_Analysis _Software.Version 2.4 _Software.DOI . _Software.Details . loop_ _Vendor.Name _Vendor.Address _Vendor.Electronic_address _Vendor.Entry_ID _Vendor.Software_ID CCPN . . 27670 3 stop_ loop_ _Task.Task _Task.Entry_ID _Task.Software_ID 'chemical shift assignment' 27670 3 stop_ save_ ######################### # Experimental detail # ######################### ################################## # NMR Spectrometer definitions # ################################## save_spectrometer_1 _NMR_spectrometer.Sf_category NMR_spectrometer _NMR_spectrometer.Sf_framecode spectrometer_1 _NMR_spectrometer.Entry_ID 27670 _NMR_spectrometer.ID 1 _NMR_spectrometer.Details . _NMR_spectrometer.Manufacturer Bruker _NMR_spectrometer.Model Avance _NMR_spectrometer.Serial_number . _NMR_spectrometer.Field_strength 800 save_ save_NMR_spectrometer_list _NMR_spectrometer_list.Sf_category NMR_spectrometer_list _NMR_spectrometer_list.Sf_framecode NMR_spectrometer_list _NMR_spectrometer_list.Entry_ID 27670 _NMR_spectrometer_list.ID 1 loop_ _NMR_spectrometer_view.ID _NMR_spectrometer_view.Name _NMR_spectrometer_view.Manufacturer _NMR_spectrometer_view.Model _NMR_spectrometer_view.Serial_number _NMR_spectrometer_view.Field_strength _NMR_spectrometer_view.Details _NMR_spectrometer_view.Citation_ID _NMR_spectrometer_view.Citation_label _NMR_spectrometer_view.Entry_ID _NMR_spectrometer_view.NMR_spectrometer_list_ID 1 spectrometer_1 Bruker Avance . 800 . . . 27670 1 stop_ save_ ############################# # NMR applied experiments # ############################# save_experiment_list _Experiment_list.Sf_category experiment_list _Experiment_list.Sf_framecode experiment_list _Experiment_list.Entry_ID 27670 _Experiment_list.ID 1 _Experiment_list.Details . loop_ _Experiment.ID _Experiment.Name _Experiment.Raw_data_flag _Experiment.NMR_spec_expt_ID _Experiment.NMR_spec_expt_label _Experiment.MS_expt_ID _Experiment.MS_expt_label _Experiment.SAXS_expt_ID _Experiment.SAXS_expt_label _Experiment.FRET_expt_ID _Experiment.FRET_expt_label _Experiment.EMR_expt_ID _Experiment.EMR_expt_label _Experiment.Sample_ID _Experiment.Sample_label _Experiment.Sample_state _Experiment.Sample_volume _Experiment.Sample_volume_units _Experiment.Sample_condition_list_ID _Experiment.Sample_condition_list_label _Experiment.Sample_spinning_rate _Experiment.Sample_angle _Experiment.NMR_tube_type _Experiment.NMR_spectrometer_ID _Experiment.NMR_spectrometer_label _Experiment.NMR_spectrometer_probe_ID _Experiment.NMR_spectrometer_probe_label _Experiment.NMR_spectral_processing_ID _Experiment.NMR_spectral_processing_label _Experiment.Mass_spectrometer_ID _Experiment.Mass_spectrometer_label _Experiment.Xray_instrument_ID _Experiment.Xray_instrument_label _Experiment.Fluorescence_instrument_ID _Experiment.Fluorescence_instrument_label _Experiment.EMR_instrument_ID _Experiment.EMR_instrument_label _Experiment.Chromatographic_system_ID _Experiment.Chromatographic_system_label _Experiment.Chromatographic_column_ID _Experiment.Chromatographic_column_label _Experiment.Entry_ID _Experiment.Experiment_list_ID 1 '2D 1H-15N HSQC' no . . . . . . . . . . 1 $sample_1 isotropic . . 1 $sample_conditions_1 . . . 1 $spectrometer_1 . . . . . . . . . . . . . . . . 27670 1 stop_ save_ #################### # NMR parameters # #################### ############################## # Assigned chemical shifts # ############################## ################################ # Chemical shift referencing # ################################ save_chemical_shift_reference_1 _Chem_shift_reference.Sf_category chem_shift_reference _Chem_shift_reference.Sf_framecode chemical_shift_reference_1 _Chem_shift_reference.Entry_ID 27670 _Chem_shift_reference.ID 1 _Chem_shift_reference.Details . loop_ _Chem_shift_ref.Atom_type _Chem_shift_ref.Atom_isotope_number _Chem_shift_ref.Mol_common_name _Chem_shift_ref.Atom_group _Chem_shift_ref.Concentration_val _Chem_shift_ref.Concentration_units _Chem_shift_ref.Solvent _Chem_shift_ref.Rank _Chem_shift_ref.Chem_shift_units _Chem_shift_ref.Chem_shift_val _Chem_shift_ref.Ref_method _Chem_shift_ref.Ref_type _Chem_shift_ref.Indirect_shift_ratio _Chem_shift_ref.External_ref_loc _Chem_shift_ref.External_ref_sample_geometry _Chem_shift_ref.External_ref_axis _Chem_shift_ref.Ref_correction_type _Chem_shift_ref.Correction_val _Chem_shift_ref.Entry_ID _Chem_shift_ref.Chem_shift_reference_ID H 1 DSS 'methyl protons' . . . . ppm 0 na direct 1 . . . . . 27670 1 N 15 urea nitrogen . . . . ppm 0 na indirect 0.251449530 . . . . . 27670 1 stop_ save_ ################################### # Assigned chemical shift lists # ################################### ################################################################### # Chemical Shift Ambiguity Index Value Definitions # # # # The values other than 1 are used for those atoms with different # # chemical shifts that cannot be assigned to stereospecific atoms # # or to specific residues or chains. # # # # Index Value Definition # # # # 1 Unique (including isolated methyl protons, # # geminal atoms, and geminal methyl # # groups with identical chemical shifts) # # (e.g. ILE HD11, HD12, HD13 protons) # # 2 Ambiguity of geminal atoms or geminal methyl # # proton groups (e.g. ASP HB2 and HB3 # # protons, LEU CD1 and CD2 carbons, or # # LEU HD11, HD12, HD13 and HD21, HD22, # # HD23 methyl protons) # # 3 Aromatic atoms on opposite sides of # # symmetrical rings (e.g. TYR HE1 and HE2 # # protons) # # 4 Intraresidue ambiguities (e.g. LYS HG and # # HD protons or TRP HZ2 and HZ3 protons) # # 5 Interresidue ambiguities (LYS 12 vs. LYS 27) # # 6 Intermolecular ambiguities (e.g. ASP 31 CA # # in monomer 1 and ASP 31 CA in monomer 2 # # of an asymmetrical homodimer, duplex # # DNA assignments, or other assignments # # that may apply to atoms in one or more # # molecule in the molecular assembly) # # 9 Ambiguous, specific ambiguity not defined # # # ################################################################### save_assigned_chem_shift_list_1 _Assigned_chem_shift_list.Sf_category assigned_chemical_shifts _Assigned_chem_shift_list.Sf_framecode assigned_chem_shift_list_1 _Assigned_chem_shift_list.Entry_ID 27670 _Assigned_chem_shift_list.ID 1 _Assigned_chem_shift_list.Sample_condition_list_ID 1 _Assigned_chem_shift_list.Sample_condition_list_label $sample_conditions_1 _Assigned_chem_shift_list.Chem_shift_reference_ID 1 _Assigned_chem_shift_list.Chem_shift_reference_label $chemical_shift_reference_1 _Assigned_chem_shift_list.Chem_shift_1H_err . _Assigned_chem_shift_list.Chem_shift_13C_err . _Assigned_chem_shift_list.Chem_shift_15N_err . _Assigned_chem_shift_list.Chem_shift_31P_err . _Assigned_chem_shift_list.Chem_shift_2H_err . _Assigned_chem_shift_list.Chem_shift_19F_err . _Assigned_chem_shift_list.Error_derivation_method . _Assigned_chem_shift_list.Details . _Assigned_chem_shift_list.Text_data_format . _Assigned_chem_shift_list.Text_data . loop_ _Chem_shift_experiment.Experiment_ID _Chem_shift_experiment.Experiment_name _Chem_shift_experiment.Sample_ID _Chem_shift_experiment.Sample_label _Chem_shift_experiment.Sample_state _Chem_shift_experiment.Entry_ID _Chem_shift_experiment.Assigned_chem_shift_list_ID 1 '2D 1H-15N HSQC' . . . 27670 1 stop_ loop_ _Atom_chem_shift.ID _Atom_chem_shift.Assembly_atom_ID _Atom_chem_shift.Entity_assembly_ID _Atom_chem_shift.Entity_ID _Atom_chem_shift.Comp_index_ID _Atom_chem_shift.Seq_ID _Atom_chem_shift.Comp_ID _Atom_chem_shift.Atom_ID _Atom_chem_shift.Atom_type _Atom_chem_shift.Atom_isotope_number _Atom_chem_shift.Val _Atom_chem_shift.Val_err _Atom_chem_shift.Assign_fig_of_merit _Atom_chem_shift.Ambiguity_code _Atom_chem_shift.Ambiguity_set_ID _Atom_chem_shift.Occupancy _Atom_chem_shift.Resonance_ID _Atom_chem_shift.Auth_entity_assembly_ID _Atom_chem_shift.Auth_asym_ID _Atom_chem_shift.Auth_seq_ID _Atom_chem_shift.Auth_comp_ID _Atom_chem_shift.Auth_atom_ID _Atom_chem_shift.Details _Atom_chem_shift.Entry_ID _Atom_chem_shift.Assigned_chem_shift_list_ID 1 . 1 1 5 5 SER H H 1 8.337 0.000 . 1 . . . . . 2 SER HN . 27670 1 2 . 1 1 5 5 SER N N 15 115.253 0.000 . 1 . . . . . 2 SER N . 27670 1 3 . 1 1 8 8 TYR H H 1 8.033 0.000 . 1 . . . . . 5 TYR HN . 27670 1 4 . 1 1 8 8 TYR N N 15 119.976 0.000 . 1 . . . . . 5 TYR N . 27670 1 5 . 1 1 9 9 GLU H H 1 8.345 0.000 . 1 . . . . . 6 GLU HN . 27670 1 6 . 1 1 9 9 GLU N N 15 122.215 0.000 . 1 . . . . . 6 GLU N . 27670 1 7 . 1 1 10 10 ASP H H 1 8.233 0.000 . 1 . . . . . 7 ASP HN . 27670 1 8 . 1 1 10 10 ASP N N 15 120.966 0.000 . 1 . . . . . 7 ASP N . 27670 1 9 . 1 1 11 11 HIS H H 1 8.231 0.000 . 1 . . . . . 8 HIS HN . 27670 1 10 . 1 1 11 11 HIS N N 15 119.346 0.000 . 1 . . . . . 8 HIS N . 27670 1 11 . 1 1 13 13 ALA H H 1 8.184 0.000 . 1 . . . . . 10 ALA HN . 27670 1 12 . 1 1 13 13 ALA N N 15 124.762 0.000 . 1 . . . . . 10 ALA N . 27670 1 13 . 1 1 14 14 GLU H H 1 8.368 0.000 . 1 . . . . . 11 GLU HN . 27670 1 14 . 1 1 14 14 GLU N N 15 119.868 0.000 . 1 . . . . . 11 GLU N . 27670 1 15 . 1 1 15 15 ASP H H 1 8.349 0.000 . 1 . . . . . 12 ASP HN . 27670 1 16 . 1 1 15 15 ASP N N 15 120.769 0.000 . 1 . . . . . 12 ASP N . 27670 1 17 . 1 1 16 16 CYS H H 1 8.278 0.000 . 1 . . . . . 13 CYS HN . 27670 1 18 . 1 1 16 16 CYS N N 15 119.564 0.000 . 1 . . . . . 13 CYS N . 27670 1 19 . 1 1 17 17 ARG H H 1 8.318 0.000 . 1 . . . . . 14 ARG HN . 27670 1 20 . 1 1 17 17 ARG N N 15 122.659 0.000 . 1 . . . . . 14 ARG N . 27670 1 21 . 1 1 19 19 ASP H H 1 8.274 0.000 . 1 . . . . . 16 ASP HN . 27670 1 22 . 1 1 19 19 ASP N N 15 120.480 0.000 . 1 . . . . . 16 ASP N . 27670 1 23 . 1 1 20 20 ILE H H 1 7.953 0.000 . 1 . . . . . 17 ILE HN . 27670 1 24 . 1 1 20 20 ILE N N 15 119.871 0.000 . 1 . . . . . 17 ILE N . 27670 1 25 . 1 1 21 21 GLY H H 1 8.484 0.000 . 1 . . . . . 18 GLY HN . 27670 1 26 . 1 1 21 21 GLY N N 15 111.423 0.000 . 1 . . . . . 18 GLY N . 27670 1 27 . 1 1 22 22 ARG H H 1 8.094 0.000 . 1 . . . . . 19 ARG HN . 27670 1 28 . 1 1 22 22 ARG N N 15 120.273 0.000 . 1 . . . . . 19 ARG N . 27670 1 29 . 1 1 24 24 ASN H H 1 7.882 0.000 . 1 . . . . . 21 ASN HN . 27670 1 30 . 1 1 24 24 ASN N N 15 120.588 0.000 . 1 . . . . . 21 ASN N . 27670 1 31 . 1 1 25 25 LEU H H 1 9.755 0.000 . 1 . . . . . 22 LEU HN . 27670 1 32 . 1 1 25 25 LEU N N 15 127.256 0.000 . 1 . . . . . 22 LEU N . 27670 1 33 . 1 1 26 26 ILE H H 1 9.229 0.000 . 1 . . . . . 23 ILE HN . 27670 1 34 . 1 1 26 26 ILE N N 15 121.156 0.000 . 1 . . . . . 23 ILE N . 27670 1 35 . 1 1 27 27 VAL H H 1 8.712 0.000 . 1 . . . . . 24 VAL HN . 27670 1 36 . 1 1 27 27 VAL N N 15 128.199 0.000 . 1 . . . . . 24 VAL N . 27670 1 37 . 1 1 28 28 ASN H H 1 9.193 0.000 . 1 . . . . . 25 ASN HN . 27670 1 38 . 1 1 28 28 ASN N N 15 123.729 0.000 . 1 . . . . . 25 ASN N . 27670 1 39 . 1 1 29 29 TYR H H 1 8.430 0.000 . 1 . . . . . 26 TYR HN . 27670 1 40 . 1 1 29 29 TYR N N 15 114.697 0.000 . 1 . . . . . 26 TYR N . 27670 1 41 . 1 1 30 30 LEU H H 1 7.968 0.000 . 1 . . . . . 27 LEU HN . 27670 1 42 . 1 1 30 30 LEU N N 15 114.307 0.000 . 1 . . . . . 27 LEU N . 27670 1 43 . 1 1 33 33 ASN H H 1 8.279 0.000 . 1 . . . . . 30 ASN HN . 27670 1 44 . 1 1 33 33 ASN N N 15 112.418 0.000 . 1 . . . . . 30 ASN N . 27670 1 45 . 1 1 34 34 MET H H 1 7.300 0.000 . 1 . . . . . 31 MET HN . 27670 1 46 . 1 1 34 34 MET N N 15 121.727 0.000 . 1 . . . . . 31 MET N . 27670 1 47 . 1 1 35 35 THR H H 1 8.622 0.000 . 1 . . . . . 32 THR HN . 27670 1 48 . 1 1 35 35 THR N N 15 118.695 0.000 . 1 . . . . . 32 THR N . 27670 1 49 . 1 1 36 36 GLN H H 1 9.251 0.000 . 1 . . . . . 33 GLN HN . 27670 1 50 . 1 1 36 36 GLN N N 15 121.667 0.000 . 1 . . . . . 33 GLN N . 27670 1 51 . 1 1 37 37 ASP H H 1 8.421 0.000 . 1 . . . . . 34 ASP HN . 27670 1 52 . 1 1 37 37 ASP N N 15 118.115 0.000 . 1 . . . . . 34 ASP N . 27670 1 53 . 1 1 38 38 GLU H H 1 7.690 0.000 . 1 . . . . . 35 GLU HN . 27670 1 54 . 1 1 38 38 GLU N N 15 121.549 0.000 . 1 . . . . . 35 GLU N . 27670 1 55 . 1 1 39 39 LEU H H 1 8.234 0.000 . 1 . . . . . 36 LEU HN . 27670 1 56 . 1 1 39 39 LEU N N 15 123.086 0.000 . 1 . . . . . 36 LEU N . 27670 1 57 . 1 1 40 40 ARG H H 1 8.362 0.000 . 1 . . . . . 37 ARG HN . 27670 1 58 . 1 1 40 40 ARG N N 15 118.214 0.000 . 1 . . . . . 37 ARG N . 27670 1 59 . 1 1 41 41 SER H H 1 8.564 0.000 . 1 . . . . . 38 SER HN . 27670 1 60 . 1 1 41 41 SER N N 15 116.225 0.000 . 1 . . . . . 38 SER N . 27670 1 61 . 1 1 42 42 LEU H H 1 8.113 0.000 . 1 . . . . . 39 LEU HN . 27670 1 62 . 1 1 42 42 LEU N N 15 122.808 0.000 . 1 . . . . . 39 LEU N . 27670 1 63 . 1 1 43 43 PHE H H 1 7.955 0.000 . 1 . . . . . 40 PHE HN . 27670 1 64 . 1 1 43 43 PHE N N 15 116.869 0.000 . 1 . . . . . 40 PHE N . 27670 1 65 . 1 1 44 44 SER H H 1 9.009 0.000 . 1 . . . . . 41 SER HN . 27670 1 66 . 1 1 44 44 SER N N 15 121.446 0.000 . 1 . . . . . 41 SER N . 27670 1 67 . 1 1 45 45 SER H H 1 7.374 0.000 . 1 . . . . . 42 SER HN . 27670 1 68 . 1 1 45 45 SER N N 15 115.867 0.000 . 1 . . . . . 42 SER N . 27670 1 69 . 1 1 46 46 ILE H H 1 7.147 0.000 . 1 . . . . . 43 ILE HN . 27670 1 70 . 1 1 46 46 ILE N N 15 120.033 0.000 . 1 . . . . . 43 ILE N . 27670 1 71 . 1 1 47 47 GLY H H 1 7.195 0.000 . 1 . . . . . 44 GLY HN . 27670 1 72 . 1 1 47 47 GLY N N 15 104.740 0.000 . 1 . . . . . 44 GLY N . 27670 1 73 . 1 1 48 48 GLU H H 1 8.264 0.000 . 1 . . . . . 45 GLU HN . 27670 1 74 . 1 1 48 48 GLU N N 15 117.266 0.000 . 1 . . . . . 45 GLU N . 27670 1 75 . 1 1 49 49 VAL H H 1 8.983 0.000 . 1 . . . . . 46 VAL HN . 27670 1 76 . 1 1 49 49 VAL N N 15 129.148 0.000 . 1 . . . . . 46 VAL N . 27670 1 77 . 1 1 50 50 GLU H H 1 9.254 0.000 . 1 . . . . . 47 GLU HN . 27670 1 78 . 1 1 50 50 GLU N N 15 130.939 0.000 . 1 . . . . . 47 GLU N . 27670 1 79 . 1 1 51 51 SER H H 1 7.660 0.000 . 1 . . . . . 48 SER HN . 27670 1 80 . 1 1 51 51 SER N N 15 109.277 0.000 . 1 . . . . . 48 SER N . 27670 1 81 . 1 1 52 52 ALA H H 1 8.158 0.000 . 1 . . . . . 49 ALA HN . 27670 1 82 . 1 1 52 52 ALA N N 15 123.132 0.000 . 1 . . . . . 49 ALA N . 27670 1 83 . 1 1 54 54 LEU H H 1 8.746 0.000 . 1 . . . . . 51 LEU HN . 27670 1 84 . 1 1 54 54 LEU N N 15 126.716 0.000 . 1 . . . . . 51 LEU N . 27670 1 85 . 1 1 55 55 ILE H H 1 8.242 0.000 . 1 . . . . . 52 ILE HN . 27670 1 86 . 1 1 55 55 ILE N N 15 127.490 0.000 . 1 . . . . . 52 ILE N . 27670 1 87 . 1 1 56 56 ARG H H 1 8.103 0.000 . 1 . . . . . 53 ARG HN . 27670 1 88 . 1 1 56 56 ARG N N 15 124.895 0.000 . 1 . . . . . 53 ARG N . 27670 1 89 . 1 1 57 57 ASP H H 1 8.596 0.000 . 1 . . . . . 54 ASP HN . 27670 1 90 . 1 1 57 57 ASP N N 15 121.972 0.000 . 1 . . . . . 54 ASP N . 27670 1 91 . 1 1 59 59 VAL H H 1 8.122 0.000 . 1 . . . . . 56 VAL HN . 27670 1 92 . 1 1 59 59 VAL N N 15 119.287 0.000 . 1 . . . . . 56 VAL N . 27670 1 93 . 1 1 60 60 ALA H H 1 8.942 0.000 . 1 . . . . . 57 ALA HN . 27670 1 94 . 1 1 60 60 ALA N N 15 122.331 0.000 . 1 . . . . . 57 ALA N . 27670 1 95 . 1 1 61 61 GLY H H 1 7.739 0.000 . 1 . . . . . 58 GLY HN . 27670 1 96 . 1 1 61 61 GLY N N 15 105.172 0.000 . 1 . . . . . 58 GLY N . 27670 1 97 . 1 1 62 62 HIS H H 1 7.492 0.000 . 1 . . . . . 59 HIS HN . 27670 1 98 . 1 1 62 62 HIS N N 15 117.588 0.000 . 1 . . . . . 59 HIS N . 27670 1 99 . 1 1 63 63 SER H H 1 8.886 0.000 . 1 . . . . . 60 SER HN . 27670 1 100 . 1 1 63 63 SER N N 15 114.324 0.000 . 1 . . . . . 60 SER N . 27670 1 101 . 1 1 64 64 LEU H H 1 9.075 0.000 . 1 . . . . . 61 LEU HN . 27670 1 102 . 1 1 64 64 LEU N N 15 125.648 0.000 . 1 . . . . . 61 LEU N . 27670 1 103 . 1 1 65 65 GLY H H 1 9.225 0.000 . 1 . . . . . 62 GLY HN . 27670 1 104 . 1 1 65 65 GLY N N 15 107.856 0.000 . 1 . . . . . 62 GLY N . 27670 1 105 . 1 1 66 66 TYR H H 1 7.344 0.000 . 1 . . . . . 63 TYR HN . 27670 1 106 . 1 1 66 66 TYR N N 15 113.195 0.000 . 1 . . . . . 63 TYR N . 27670 1 107 . 1 1 67 67 GLY H H 1 8.631 0.000 . 1 . . . . . 64 GLY HN . 27670 1 108 . 1 1 67 67 GLY N N 15 104.926 0.000 . 1 . . . . . 64 GLY N . 27670 1 109 . 1 1 68 68 PHE H H 1 8.790 0.000 . 1 . . . . . 65 PHE HN . 27670 1 110 . 1 1 68 68 PHE N N 15 116.368 0.000 . 1 . . . . . 65 PHE N . 27670 1 111 . 1 1 69 69 VAL H H 1 8.674 0.000 . 1 . . . . . 66 VAL HN . 27670 1 112 . 1 1 69 69 VAL N N 15 122.912 0.000 . 1 . . . . . 66 VAL N . 27670 1 113 . 1 1 71 71 TYR H H 1 8.634 0.000 . 1 . . . . . 68 TYR HN . 27670 1 114 . 1 1 71 71 TYR N N 15 126.046 0.000 . 1 . . . . . 68 TYR N . 27670 1 115 . 1 1 72 72 VAL H H 1 7.830 0.000 . 1 . . . . . 69 VAL HN . 27670 1 116 . 1 1 72 72 VAL N N 15 118.450 0.000 . 1 . . . . . 69 VAL N . 27670 1 117 . 1 1 73 73 THR H H 1 9.025 0.000 . 1 . . . . . 70 THR HN . 27670 1 118 . 1 1 73 73 THR N N 15 109.848 0.000 . 1 . . . . . 70 THR N . 27670 1 119 . 1 1 74 74 ALA H H 1 8.841 0.000 . 1 . . . . . 71 ALA HN . 27670 1 120 . 1 1 74 74 ALA N N 15 127.036 0.000 . 1 . . . . . 71 ALA N . 27670 1 121 . 1 1 75 75 LYS H H 1 8.441 0.000 . 1 . . . . . 72 LYS HN . 27670 1 122 . 1 1 75 75 LYS N N 15 118.834 0.000 . 1 . . . . . 72 LYS N . 27670 1 123 . 1 1 76 76 ASP H H 1 7.380 0.000 . 1 . . . . . 73 ASP HN . 27670 1 124 . 1 1 76 76 ASP N N 15 119.963 0.000 . 1 . . . . . 73 ASP N . 27670 1 125 . 1 1 77 77 ALA H H 1 7.055 0.000 . 1 . . . . . 74 ALA HN . 27670 1 126 . 1 1 77 77 ALA N N 15 122.308 0.000 . 1 . . . . . 74 ALA N . 27670 1 127 . 1 1 78 78 GLU H H 1 7.751 0.000 . 1 . . . . . 75 GLU HN . 27670 1 128 . 1 1 78 78 GLU N N 15 116.908 0.000 . 1 . . . . . 75 GLU N . 27670 1 129 . 1 1 79 79 ARG H H 1 7.758 0.000 . 1 . . . . . 76 ARG HN . 27670 1 130 . 1 1 79 79 ARG N N 15 119.313 0.000 . 1 . . . . . 76 ARG N . 27670 1 131 . 1 1 80 80 ALA H H 1 8.567 0.000 . 1 . . . . . 77 ALA HN . 27670 1 132 . 1 1 80 80 ALA N N 15 124.989 0.000 . 1 . . . . . 77 ALA N . 27670 1 133 . 1 1 81 81 ILE H H 1 7.867 0.000 . 1 . . . . . 78 ILE HN . 27670 1 134 . 1 1 81 81 ILE N N 15 119.327 0.000 . 1 . . . . . 78 ILE N . 27670 1 135 . 1 1 82 82 ASN H H 1 7.731 0.000 . 1 . . . . . 79 ASN HN . 27670 1 136 . 1 1 82 82 ASN N N 15 114.792 0.000 . 1 . . . . . 79 ASN N . 27670 1 137 . 1 1 83 83 THR H H 1 8.171 0.000 . 1 . . . . . 80 THR HN . 27670 1 138 . 1 1 83 83 THR N N 15 112.288 0.000 . 1 . . . . . 80 THR N . 27670 1 139 . 1 1 84 84 LEU H H 1 8.662 0.000 . 1 . . . . . 81 LEU HN . 27670 1 140 . 1 1 84 84 LEU N N 15 119.185 0.000 . 1 . . . . . 81 LEU N . 27670 1 141 . 1 1 85 85 ASN H H 1 7.461 0.000 . 1 . . . . . 82 ASN HN . 27670 1 142 . 1 1 85 85 ASN N N 15 114.959 0.000 . 1 . . . . . 82 ASN N . 27670 1 143 . 1 1 87 87 LEU H H 1 7.484 0.000 . 1 . . . . . 84 LEU HN . 27670 1 144 . 1 1 87 87 LEU N N 15 123.564 0.000 . 1 . . . . . 84 LEU N . 27670 1 145 . 1 1 88 88 ARG H H 1 8.245 0.000 . 1 . . . . . 85 ARG HN . 27670 1 146 . 1 1 88 88 ARG N N 15 125.996 0.000 . 1 . . . . . 85 ARG N . 27670 1 147 . 1 1 89 89 LEU H H 1 8.658 0.000 . 1 . . . . . 86 LEU HN . 27670 1 148 . 1 1 89 89 LEU N N 15 128.517 0.000 . 1 . . . . . 86 LEU N . 27670 1 149 . 1 1 90 90 GLN H H 1 9.115 0.000 . 1 . . . . . 87 GLN HN . 27670 1 150 . 1 1 90 90 GLN N N 15 121.050 0.000 . 1 . . . . . 87 GLN N . 27670 1 151 . 1 1 91 91 SER H H 1 8.312 0.000 . 1 . . . . . 88 SER HN . 27670 1 152 . 1 1 91 91 SER N N 15 113.089 0.000 . 1 . . . . . 88 SER N . 27670 1 153 . 1 1 92 92 LYS H H 1 8.192 0.000 . 1 . . . . . 89 LYS HN . 27670 1 154 . 1 1 92 92 LYS N N 15 122.358 0.000 . 1 . . . . . 89 LYS N . 27670 1 155 . 1 1 93 93 THR H H 1 8.133 0.000 . 1 . . . . . 90 THR HN . 27670 1 156 . 1 1 93 93 THR N N 15 117.681 0.000 . 1 . . . . . 90 THR N . 27670 1 157 . 1 1 94 94 ILE H H 1 8.587 0.000 . 1 . . . . . 91 ILE HN . 27670 1 158 . 1 1 94 94 ILE N N 15 121.411 0.000 . 1 . . . . . 91 ILE N . 27670 1 159 . 1 1 95 95 LYS H H 1 8.376 0.000 . 1 . . . . . 92 LYS HN . 27670 1 160 . 1 1 95 95 LYS N N 15 123.609 0.000 . 1 . . . . . 92 LYS N . 27670 1 161 . 1 1 96 96 VAL H H 1 8.814 0.000 . 1 . . . . . 93 VAL HN . 27670 1 162 . 1 1 96 96 VAL N N 15 126.963 0.000 . 1 . . . . . 93 VAL N . 27670 1 163 . 1 1 97 97 SER H H 1 8.620 0.000 . 1 . . . . . 94 SER HN . 27670 1 164 . 1 1 97 97 SER N N 15 119.093 0.000 . 1 . . . . . 94 SER N . 27670 1 165 . 1 1 98 98 TYR H H 1 8.475 0.000 . 1 . . . . . 95 TYR HN . 27670 1 166 . 1 1 98 98 TYR N N 15 119.886 0.000 . 1 . . . . . 95 TYR N . 27670 1 167 . 1 1 99 99 ALA H H 1 8.789 0.000 . 1 . . . . . 96 ALA HN . 27670 1 168 . 1 1 99 99 ALA N N 15 125.273 0.000 . 1 . . . . . 96 ALA N . 27670 1 169 . 1 1 100 100 ARG H H 1 8.832 0.000 . 1 . . . . . 97 ARG HN . 27670 1 170 . 1 1 100 100 ARG N N 15 121.380 0.000 . 1 . . . . . 97 ARG N . 27670 1 171 . 1 1 103 103 SER H H 1 8.361 0.000 . 1 . . . . . 100 SER HN . 27670 1 172 . 1 1 103 103 SER N N 15 116.725 0.000 . 1 . . . . . 100 SER N . 27670 1 173 . 1 1 104 104 GLU H H 1 8.255 0.000 . 1 . . . . . 101 GLU HN . 27670 1 174 . 1 1 104 104 GLU N N 15 122.308 0.000 . 1 . . . . . 101 GLU N . 27670 1 175 . 1 1 105 105 VAL H H 1 8.009 0.000 . 1 . . . . . 102 VAL HN . 27670 1 176 . 1 1 105 105 VAL N N 15 121.171 0.000 . 1 . . . . . 102 VAL N . 27670 1 177 . 1 1 106 106 ILE H H 1 8.077 0.000 . 1 . . . . . 103 ILE HN . 27670 1 178 . 1 1 106 106 ILE N N 15 124.122 0.000 . 1 . . . . . 103 ILE N . 27670 1 179 . 1 1 107 107 LYS H H 1 8.279 0.000 . 1 . . . . . 104 LYS HN . 27670 1 180 . 1 1 107 107 LYS N N 15 124.719 0.000 . 1 . . . . . 104 LYS N . 27670 1 181 . 1 1 108 108 ASP H H 1 7.962 0.000 . 1 . . . . . 105 ASP HN . 27670 1 182 . 1 1 108 108 ASP N N 15 121.860 0.000 . 1 . . . . . 105 ASP N . 27670 1 183 . 1 1 109 109 ALA H H 1 8.471 0.000 . 1 . . . . . 106 ALA HN . 27670 1 184 . 1 1 109 109 ALA N N 15 125.004 0.000 . 1 . . . . . 106 ALA N . 27670 1 185 . 1 1 111 111 LEU H H 1 9.665 0.000 . 1 . . . . . 108 LEU HN . 27670 1 186 . 1 1 111 111 LEU N N 15 125.531 0.000 . 1 . . . . . 108 LEU N . 27670 1 187 . 1 1 112 112 TYR H H 1 9.226 0.000 . 1 . . . . . 109 TYR HN . 27670 1 188 . 1 1 112 112 TYR N N 15 122.679 0.000 . 1 . . . . . 109 TYR N . 27670 1 189 . 1 1 113 113 ILE H H 1 8.483 0.000 . 1 . . . . . 110 ILE HN . 27670 1 190 . 1 1 113 113 ILE N N 15 128.852 0.000 . 1 . . . . . 110 ILE N . 27670 1 191 . 1 1 118 118 ARG H H 1 9.143 0.000 . 1 . . . . . 115 ARG HN . 27670 1 192 . 1 1 118 118 ARG N N 15 124.196 0.000 . 1 . . . . . 115 ARG N . 27670 1 193 . 1 1 119 119 THR H H 1 7.215 0.000 . 1 . . . . . 116 THR HN . 27670 1 194 . 1 1 119 119 THR N N 15 103.967 0.000 . 1 . . . . . 116 THR N . 27670 1 195 . 1 1 120 120 MET H H 1 7.185 0.000 . 1 . . . . . 117 MET HN . 27670 1 196 . 1 1 120 120 MET N N 15 119.975 0.000 . 1 . . . . . 117 MET N . 27670 1 197 . 1 1 121 121 THR H H 1 9.326 0.000 . 1 . . . . . 118 THR HN . 27670 1 198 . 1 1 121 121 THR N N 15 116.756 0.000 . 1 . . . . . 118 THR N . 27670 1 199 . 1 1 122 122 GLN H H 1 9.029 0.000 . 1 . . . . . 119 GLN HN . 27670 1 200 . 1 1 122 122 GLN N N 15 120.242 0.000 . 1 . . . . . 119 GLN N . 27670 1 201 . 1 1 123 123 LYS H H 1 8.129 0.000 . 1 . . . . . 120 LYS HN . 27670 1 202 . 1 1 123 123 LYS N N 15 119.013 0.000 . 1 . . . . . 120 LYS N . 27670 1 203 . 1 1 124 124 ASP H H 1 7.491 0.000 . 1 . . . . . 121 ASP HN . 27670 1 204 . 1 1 124 124 ASP N N 15 118.617 0.000 . 1 . . . . . 121 ASP N . 27670 1 205 . 1 1 125 125 VAL H H 1 8.263 0.000 . 1 . . . . . 122 VAL HN . 27670 1 206 . 1 1 125 125 VAL N N 15 121.579 0.000 . 1 . . . . . 122 VAL N . 27670 1 207 . 1 1 126 126 GLU H H 1 8.402 0.000 . 1 . . . . . 123 GLU HN . 27670 1 208 . 1 1 126 126 GLU N N 15 120.432 0.000 . 1 . . . . . 123 GLU N . 27670 1 209 . 1 1 127 127 ASP H H 1 8.813 0.000 . 1 . . . . . 124 ASP HN . 27670 1 210 . 1 1 127 127 ASP N N 15 119.353 0.000 . 1 . . . . . 124 ASP N . 27670 1 211 . 1 1 128 128 MET H H 1 7.858 0.000 . 1 . . . . . 125 MET HN . 27670 1 212 . 1 1 128 128 MET N N 15 119.814 0.000 . 1 . . . . . 125 MET N . 27670 1 213 . 1 1 129 129 PHE H H 1 7.995 0.000 . 1 . . . . . 126 PHE HN . 27670 1 214 . 1 1 129 129 PHE N N 15 113.788 0.000 . 1 . . . . . 126 PHE N . 27670 1 215 . 1 1 130 130 SER H H 1 8.536 0.000 . 1 . . . . . 127 SER HN . 27670 1 216 . 1 1 130 130 SER N N 15 117.809 0.000 . 1 . . . . . 127 SER N . 27670 1 217 . 1 1 131 131 ARG H H 1 7.160 0.000 . 1 . . . . . 128 ARG HN . 27670 1 218 . 1 1 131 131 ARG N N 15 117.755 0.000 . 1 . . . . . 128 ARG N . 27670 1 219 . 1 1 132 132 PHE H H 1 7.439 0.000 . 1 . . . . . 129 PHE HN . 27670 1 220 . 1 1 132 132 PHE N N 15 116.822 0.000 . 1 . . . . . 129 PHE N . 27670 1 221 . 1 1 133 133 GLY H H 1 7.453 0.000 . 1 . . . . . 130 GLY HN . 27670 1 222 . 1 1 133 133 GLY N N 15 104.184 0.000 . 1 . . . . . 130 GLY N . 27670 1 223 . 1 1 134 134 ARG H H 1 8.317 0.000 . 1 . . . . . 131 ARG HN . 27670 1 224 . 1 1 134 134 ARG N N 15 119.964 0.000 . 1 . . . . . 131 ARG N . 27670 1 225 . 1 1 135 135 ILE H H 1 8.577 0.000 . 1 . . . . . 132 ILE HN . 27670 1 226 . 1 1 135 135 ILE N N 15 127.868 0.000 . 1 . . . . . 132 ILE N . 27670 1 227 . 1 1 136 136 ILE H H 1 9.010 0.000 . 1 . . . . . 133 ILE HN . 27670 1 228 . 1 1 136 136 ILE N N 15 127.764 0.000 . 1 . . . . . 133 ILE N . 27670 1 229 . 1 1 137 137 ASN H H 1 7.442 0.000 . 1 . . . . . 134 ASN HN . 27670 1 230 . 1 1 137 137 ASN N N 15 114.595 0.000 . 1 . . . . . 134 ASN N . 27670 1 231 . 1 1 138 138 SER H H 1 8.252 0.000 . 1 . . . . . 135 SER HN . 27670 1 232 . 1 1 138 138 SER N N 15 115.371 0.000 . 1 . . . . . 135 SER N . 27670 1 233 . 1 1 139 139 ARG H H 1 8.643 0.000 . 1 . . . . . 136 ARG HN . 27670 1 234 . 1 1 139 139 ARG N N 15 118.183 0.000 . 1 . . . . . 136 ARG N . 27670 1 235 . 1 1 140 140 VAL H H 1 8.708 0.000 . 1 . . . . . 137 VAL HN . 27670 1 236 . 1 1 140 140 VAL N N 15 124.096 0.000 . 1 . . . . . 137 VAL N . 27670 1 237 . 1 1 141 141 LEU H H 1 8.639 0.000 . 1 . . . . . 138 LEU HN . 27670 1 238 . 1 1 141 141 LEU N N 15 128.420 0.000 . 1 . . . . . 138 LEU N . 27670 1 239 . 1 1 142 142 VAL H H 1 8.340 0.000 . 1 . . . . . 139 VAL HN . 27670 1 240 . 1 1 142 142 VAL N N 15 118.946 0.000 . 1 . . . . . 139 VAL N . 27670 1 241 . 1 1 143 143 ASP H H 1 8.698 0.000 . 1 . . . . . 140 ASP HN . 27670 1 242 . 1 1 143 143 ASP N N 15 125.391 0.000 . 1 . . . . . 140 ASP N . 27670 1 243 . 1 1 144 144 GLN H H 1 9.186 0.000 . 1 . . . . . 141 GLN HN . 27670 1 244 . 1 1 144 144 GLN N N 15 126.939 0.000 . 1 . . . . . 141 GLN N . 27670 1 245 . 1 1 145 145 THR H H 1 8.716 0.000 . 1 . . . . . 142 THR HN . 27670 1 246 . 1 1 145 145 THR N N 15 113.654 0.000 . 1 . . . . . 142 THR N . 27670 1 247 . 1 1 146 146 THR H H 1 7.865 0.000 . 1 . . . . . 143 THR HN . 27670 1 248 . 1 1 146 146 THR N N 15 109.699 0.000 . 1 . . . . . 143 THR N . 27670 1 249 . 1 1 148 148 LEU H H 1 7.803 0.000 . 1 . . . . . 145 LEU HN . 27670 1 250 . 1 1 148 148 LEU N N 15 119.996 0.000 . 1 . . . . . 145 LEU N . 27670 1 251 . 1 1 149 149 SER H H 1 8.634 0.000 . 1 . . . . . 146 SER HN . 27670 1 252 . 1 1 149 149 SER N N 15 115.078 0.000 . 1 . . . . . 146 SER N . 27670 1 253 . 1 1 150 150 ARG H H 1 8.917 0.000 . 1 . . . . . 147 ARG HN . 27670 1 254 . 1 1 150 150 ARG N N 15 123.412 0.000 . 1 . . . . . 147 ARG N . 27670 1 255 . 1 1 151 151 GLY H H 1 9.604 0.000 . 1 . . . . . 148 GLY HN . 27670 1 256 . 1 1 151 151 GLY N N 15 109.760 0.000 . 1 . . . . . 148 GLY N . 27670 1 257 . 1 1 152 152 VAL H H 1 6.498 0.000 . 1 . . . . . 149 VAL HN . 27670 1 258 . 1 1 152 152 VAL N N 15 115.733 0.000 . 1 . . . . . 149 VAL N . 27670 1 259 . 1 1 153 153 ALA H H 1 9.092 0.000 . 1 . . . . . 150 ALA HN . 27670 1 260 . 1 1 153 153 ALA N N 15 126.589 0.000 . 1 . . . . . 150 ALA N . 27670 1 261 . 1 1 154 154 PHE H H 1 8.613 0.000 . 1 . . . . . 151 PHE HN . 27670 1 262 . 1 1 154 154 PHE N N 15 116.598 0.000 . 1 . . . . . 151 PHE N . 27670 1 263 . 1 1 155 155 ILE H H 1 8.221 0.000 . 1 . . . . . 152 ILE HN . 27670 1 264 . 1 1 155 155 ILE N N 15 120.353 0.000 . 1 . . . . . 152 ILE N . 27670 1 265 . 1 1 156 156 ARG H H 1 8.507 0.000 . 1 . . . . . 153 ARG HN . 27670 1 266 . 1 1 156 156 ARG N N 15 127.399 0.000 . 1 . . . . . 153 ARG N . 27670 1 267 . 1 1 157 157 PHE H H 1 8.371 0.000 . 1 . . . . . 154 PHE HN . 27670 1 268 . 1 1 157 157 PHE N N 15 126.847 0.000 . 1 . . . . . 154 PHE N . 27670 1 269 . 1 1 158 158 ASP H H 1 8.790 0.000 . 1 . . . . . 155 ASP HN . 27670 1 270 . 1 1 158 158 ASP N N 15 120.389 0.000 . 1 . . . . . 155 ASP N . 27670 1 271 . 1 1 159 159 LYS H H 1 8.435 0.000 . 1 . . . . . 156 LYS HN . 27670 1 272 . 1 1 159 159 LYS N N 15 113.421 0.000 . 1 . . . . . 156 LYS N . 27670 1 273 . 1 1 160 160 ARG H H 1 9.106 0.000 . 1 . . . . . 157 ARG HN . 27670 1 274 . 1 1 160 160 ARG N N 15 125.662 0.000 . 1 . . . . . 157 ARG N . 27670 1 275 . 1 1 161 161 SER H H 1 8.670 0.000 . 1 . . . . . 158 SER HN . 27670 1 276 . 1 1 161 161 SER N N 15 112.808 0.000 . 1 . . . . . 158 SER N . 27670 1 277 . 1 1 162 162 GLU H H 1 6.900 0.000 . 1 . . . . . 159 GLU HN . 27670 1 278 . 1 1 162 162 GLU N N 15 124.157 0.000 . 1 . . . . . 159 GLU N . 27670 1 279 . 1 1 163 163 ALA H H 1 6.802 0.000 . 1 . . . . . 160 ALA HN . 27670 1 280 . 1 1 163 163 ALA N N 15 119.639 0.000 . 1 . . . . . 160 ALA N . 27670 1 281 . 1 1 164 164 GLU H H 1 8.634 0.000 . 1 . . . . . 161 GLU HN . 27670 1 282 . 1 1 164 164 GLU N N 15 115.373 0.000 . 1 . . . . . 161 GLU N . 27670 1 283 . 1 1 165 165 GLU H H 1 7.495 0.000 . 1 . . . . . 162 GLU HN . 27670 1 284 . 1 1 165 165 GLU N N 15 120.383 0.000 . 1 . . . . . 162 GLU N . 27670 1 285 . 1 1 166 166 ALA H H 1 7.316 0.000 . 1 . . . . . 163 ALA HN . 27670 1 286 . 1 1 166 166 ALA N N 15 123.163 0.000 . 1 . . . . . 163 ALA N . 27670 1 287 . 1 1 167 167 ILE H H 1 7.679 0.000 . 1 . . . . . 164 ILE HN . 27670 1 288 . 1 1 167 167 ILE N N 15 117.805 0.000 . 1 . . . . . 164 ILE N . 27670 1 289 . 1 1 168 168 THR H H 1 8.104 0.000 . 1 . . . . . 165 THR HN . 27670 1 290 . 1 1 168 168 THR N N 15 114.826 0.000 . 1 . . . . . 165 THR N . 27670 1 291 . 1 1 169 169 SER H H 1 7.968 0.000 . 1 . . . . . 166 SER HN . 27670 1 292 . 1 1 169 169 SER N N 15 113.661 0.000 . 1 . . . . . 166 SER N . 27670 1 293 . 1 1 170 170 PHE H H 1 8.124 0.000 . 1 . . . . . 167 PHE HN . 27670 1 294 . 1 1 170 170 PHE N N 15 117.044 0.000 . 1 . . . . . 167 PHE N . 27670 1 295 . 1 1 171 171 ASN H H 1 8.695 0.000 . 1 . . . . . 168 ASN HN . 27670 1 296 . 1 1 171 171 ASN N N 15 119.169 0.000 . 1 . . . . . 168 ASN N . 27670 1 297 . 1 1 172 172 GLY H H 1 9.379 0.000 . 1 . . . . . 169 GLY HN . 27670 1 298 . 1 1 172 172 GLY N N 15 118.204 0.000 . 1 . . . . . 169 GLY N . 27670 1 299 . 1 1 173 173 HIS H H 1 8.058 0.000 . 1 . . . . . 170 HIS HN . 27670 1 300 . 1 1 173 173 HIS N N 15 121.657 0.000 . 1 . . . . . 170 HIS N . 27670 1 301 . 1 1 174 174 LYS H H 1 8.013 0.000 . 1 . . . . . 171 LYS HN . 27670 1 302 . 1 1 174 174 LYS N N 15 126.563 0.000 . 1 . . . . . 171 LYS N . 27670 1 303 . 1 1 178 178 SER H H 1 8.015 0.000 . 1 . . . . . 175 SER HN . 27670 1 304 . 1 1 178 178 SER N N 15 115.283 0.000 . 1 . . . . . 175 SER N . 27670 1 305 . 1 1 179 179 SER H H 1 8.762 0.000 . 1 . . . . . 176 SER HN . 27670 1 306 . 1 1 179 179 SER N N 15 117.832 0.000 . 1 . . . . . 176 SER N . 27670 1 307 . 1 1 180 180 GLU H H 1 7.888 0.000 . 1 . . . . . 177 GLU HN . 27670 1 308 . 1 1 180 180 GLU N N 15 121.848 0.000 . 1 . . . . . 177 GLU N . 27670 1 309 . 1 1 182 182 ILE H H 1 8.594 0.000 . 1 . . . . . 179 ILE HN . 27670 1 310 . 1 1 182 182 ILE N N 15 118.608 0.000 . 1 . . . . . 179 ILE N . 27670 1 311 . 1 1 183 183 THR H H 1 8.839 0.000 . 1 . . . . . 180 THR HN . 27670 1 312 . 1 1 183 183 THR N N 15 121.059 0.000 . 1 . . . . . 180 THR N . 27670 1 313 . 1 1 184 184 VAL H H 1 8.712 0.000 . 1 . . . . . 181 VAL HN . 27670 1 314 . 1 1 184 184 VAL N N 15 124.867 0.000 . 1 . . . . . 181 VAL N . 27670 1 315 . 1 1 185 185 LYS H H 1 8.758 0.000 . 1 . . . . . 182 LYS HN . 27670 1 316 . 1 1 185 185 LYS N N 15 122.742 0.000 . 1 . . . . . 182 LYS N . 27670 1 317 . 1 1 186 186 PHE H H 1 8.623 0.000 . 1 . . . . . 183 PHE HN . 27670 1 318 . 1 1 186 186 PHE N N 15 119.859 0.000 . 1 . . . . . 183 PHE N . 27670 1 319 . 1 1 248 248 CYS H H 1 9.008 0.000 . 1 . . . . . 245 CYS HN . 27670 1 320 . 1 1 248 248 CYS N N 15 124.296 0.000 . 1 . . . . . 245 CYS N . 27670 1 321 . 1 1 249 249 ILE H H 1 9.807 0.000 . 1 . . . . . 246 ILE HN . 27670 1 322 . 1 1 249 249 ILE N N 15 132.358 0.000 . 1 . . . . . 246 ILE N . 27670 1 323 . 1 1 250 250 PHE H H 1 9.495 0.000 . 1 . . . . . 247 PHE HN . 27670 1 324 . 1 1 250 250 PHE N N 15 127.832 0.000 . 1 . . . . . 247 PHE N . 27670 1 325 . 1 1 251 251 ILE H H 1 8.311 0.000 . 1 . . . . . 248 ILE HN . 27670 1 326 . 1 1 251 251 ILE N N 15 125.467 0.000 . 1 . . . . . 248 ILE N . 27670 1 327 . 1 1 252 252 TYR H H 1 9.093 0.000 . 1 . . . . . 249 TYR HN . 27670 1 328 . 1 1 252 252 TYR N N 15 124.375 0.000 . 1 . . . . . 249 TYR N . 27670 1 329 . 1 1 253 253 ASN H H 1 7.629 0.000 . 1 . . . . . 250 ASN HN . 27670 1 330 . 1 1 253 253 ASN N N 15 117.171 0.000 . 1 . . . . . 250 ASN N . 27670 1 331 . 1 1 254 254 LEU H H 1 7.248 0.000 . 1 . . . . . 251 LEU HN . 27670 1 332 . 1 1 254 254 LEU N N 15 113.688 0.000 . 1 . . . . . 251 LEU N . 27670 1 333 . 1 1 255 255 GLY H H 1 8.433 0.000 . 1 . . . . . 252 GLY HN . 27670 1 334 . 1 1 255 255 GLY N N 15 107.887 0.000 . 1 . . . . . 252 GLY N . 27670 1 335 . 1 1 257 257 ASP H H 1 8.597 0.000 . 1 . . . . . 254 ASP HN . 27670 1 336 . 1 1 257 257 ASP N N 15 116.780 0.000 . 1 . . . . . 254 ASP N . 27670 1 337 . 1 1 258 258 ALA H H 1 7.186 0.000 . 1 . . . . . 255 ALA HN . 27670 1 338 . 1 1 258 258 ALA N N 15 123.433 0.000 . 1 . . . . . 255 ALA N . 27670 1 339 . 1 1 259 259 ASP H H 1 7.102 0.000 . 1 . . . . . 256 ASP HN . 27670 1 340 . 1 1 259 259 ASP N N 15 116.404 0.000 . 1 . . . . . 256 ASP N . 27670 1 341 . 1 1 260 260 GLU H H 1 9.642 0.000 . 1 . . . . . 257 GLU HN . 27670 1 342 . 1 1 260 260 GLU N N 15 118.950 0.000 . 1 . . . . . 257 GLU N . 27670 1 343 . 1 1 261 261 GLY H H 1 8.608 0.000 . 1 . . . . . 258 GLY HN . 27670 1 344 . 1 1 261 261 GLY N N 15 106.734 0.000 . 1 . . . . . 258 GLY N . 27670 1 345 . 1 1 262 262 ILE H H 1 7.748 0.000 . 1 . . . . . 259 ILE HN . 27670 1 346 . 1 1 262 262 ILE N N 15 120.777 0.000 . 1 . . . . . 259 ILE N . 27670 1 347 . 1 1 274 274 THR H H 1 8.256 0.000 . 1 . . . . . 271 THR HN . 27670 1 348 . 1 1 274 274 THR N N 15 114.076 0.000 . 1 . . . . . 271 THR N . 27670 1 349 . 1 1 275 275 ASN H H 1 7.327 0.000 . 1 . . . . . 272 ASN HN . 27670 1 350 . 1 1 275 275 ASN N N 15 118.327 0.000 . 1 . . . . . 272 ASN N . 27670 1 351 . 1 1 276 276 VAL H H 1 7.914 0.000 . 1 . . . . . 273 VAL HN . 27670 1 352 . 1 1 276 276 VAL N N 15 119.739 0.000 . 1 . . . . . 273 VAL N . 27670 1 353 . 1 1 277 277 LYS H H 1 8.743 0.000 . 1 . . . . . 274 LYS HN . 27670 1 354 . 1 1 277 277 LYS N N 15 124.482 0.000 . 1 . . . . . 274 LYS N . 27670 1 355 . 1 1 279 279 ILE H H 1 7.886 0.000 . 1 . . . . . 276 ILE HN . 27670 1 356 . 1 1 279 279 ILE N N 15 126.560 0.000 . 1 . . . . . 276 ILE N . 27670 1 357 . 1 1 280 280 ARG H H 1 8.661 0.000 . 1 . . . . . 277 ARG HN . 27670 1 358 . 1 1 280 280 ARG N N 15 127.267 0.000 . 1 . . . . . 277 ARG N . 27670 1 359 . 1 1 281 281 ASP H H 1 8.469 0.000 . 1 . . . . . 278 ASP HN . 27670 1 360 . 1 1 281 281 ASP N N 15 121.818 0.000 . 1 . . . . . 278 ASP N . 27670 1 361 . 1 1 282 282 PHE H H 1 8.874 0.000 . 1 . . . . . 279 PHE HN . 27670 1 362 . 1 1 282 282 PHE N N 15 126.999 0.000 . 1 . . . . . 279 PHE N . 27670 1 363 . 1 1 283 283 ASN H H 1 8.700 0.000 . 1 . . . . . 280 ASN HN . 27670 1 364 . 1 1 283 283 ASN N N 15 116.066 0.000 . 1 . . . . . 280 ASN N . 27670 1 365 . 1 1 284 284 THR H H 1 8.186 0.000 . 1 . . . . . 281 THR HN . 27670 1 366 . 1 1 284 284 THR N N 15 108.031 0.000 . 1 . . . . . 281 THR N . 27670 1 367 . 1 1 286 286 LYS H H 1 7.747 0.000 . 1 . . . . . 283 LYS HN . 27670 1 368 . 1 1 286 286 LYS N N 15 117.121 0.000 . 1 . . . . . 283 LYS N . 27670 1 369 . 1 1 287 287 CYS H H 1 8.913 0.000 . 1 . . . . . 284 CYS HN . 27670 1 370 . 1 1 287 287 CYS N N 15 121.908 0.000 . 1 . . . . . 284 CYS N . 27670 1 371 . 1 1 288 288 LYS H H 1 9.087 0.000 . 1 . . . . . 285 LYS HN . 27670 1 372 . 1 1 288 288 LYS N N 15 128.728 0.000 . 1 . . . . . 285 LYS N . 27670 1 373 . 1 1 289 289 GLY H H 1 8.494 0.000 . 1 . . . . . 286 GLY HN . 27670 1 374 . 1 1 289 289 GLY N N 15 107.311 0.000 . 1 . . . . . 286 GLY N . 27670 1 375 . 1 1 290 290 PHE H H 1 6.819 0.000 . 1 . . . . . 287 PHE HN . 27670 1 376 . 1 1 290 290 PHE N N 15 115.598 0.000 . 1 . . . . . 287 PHE N . 27670 1 377 . 1 1 291 291 GLY H H 1 8.626 0.000 . 1 . . . . . 288 GLY HN . 27670 1 378 . 1 1 291 291 GLY N N 15 105.900 0.000 . 1 . . . . . 288 GLY N . 27670 1 379 . 1 1 292 292 PHE H H 1 8.978 0.000 . 1 . . . . . 289 PHE HN . 27670 1 380 . 1 1 292 292 PHE N N 15 114.671 0.000 . 1 . . . . . 289 PHE N . 27670 1 381 . 1 1 293 293 VAL H H 1 8.935 0.000 . 1 . . . . . 290 VAL HN . 27670 1 382 . 1 1 293 293 VAL N N 15 120.823 0.000 . 1 . . . . . 290 VAL N . 27670 1 383 . 1 1 294 294 THR H H 1 8.635 0.000 . 1 . . . . . 291 THR HN . 27670 1 384 . 1 1 294 294 THR N N 15 121.331 0.000 . 1 . . . . . 291 THR N . 27670 1 385 . 1 1 295 295 MET H H 1 8.887 0.000 . 1 . . . . . 292 MET HN . 27670 1 386 . 1 1 295 295 MET N N 15 124.769 0.000 . 1 . . . . . 292 MET N . 27670 1 387 . 1 1 297 297 ASN H H 1 9.927 0.000 . 1 . . . . . 294 ASN HN . 27670 1 388 . 1 1 297 297 ASN N N 15 120.106 0.000 . 1 . . . . . 294 ASN N . 27670 1 389 . 1 1 298 298 TYR H H 1 9.108 0.000 . 1 . . . . . 295 TYR HN . 27670 1 390 . 1 1 298 298 TYR N N 15 128.480 0.000 . 1 . . . . . 295 TYR N . 27670 1 391 . 1 1 299 299 GLU H H 1 9.069 0.000 . 1 . . . . . 296 GLU HN . 27670 1 392 . 1 1 299 299 GLU N N 15 115.726 0.000 . 1 . . . . . 296 GLU N . 27670 1 393 . 1 1 300 300 GLU H H 1 7.104 0.000 . 1 . . . . . 297 GLU HN . 27670 1 394 . 1 1 300 300 GLU N N 15 119.584 0.000 . 1 . . . . . 297 GLU N . 27670 1 395 . 1 1 301 301 ALA H H 1 7.970 0.000 . 1 . . . . . 298 ALA HN . 27670 1 396 . 1 1 301 301 ALA N N 15 122.812 0.000 . 1 . . . . . 298 ALA N . 27670 1 397 . 1 1 302 302 ALA H H 1 8.753 0.000 . 1 . . . . . 299 ALA HN . 27670 1 398 . 1 1 302 302 ALA N N 15 118.469 0.000 . 1 . . . . . 299 ALA N . 27670 1 399 . 1 1 303 303 MET H H 1 7.575 0.000 . 1 . . . . . 300 MET HN . 27670 1 400 . 1 1 303 303 MET N N 15 119.196 0.000 . 1 . . . . . 300 MET N . 27670 1 401 . 1 1 304 304 ALA H H 1 8.010 0.000 . 1 . . . . . 301 ALA HN . 27670 1 402 . 1 1 304 304 ALA N N 15 125.572 0.000 . 1 . . . . . 301 ALA N . 27670 1 403 . 1 1 305 305 ILE H H 1 8.081 0.000 . 1 . . . . . 302 ILE HN . 27670 1 404 . 1 1 305 305 ILE N N 15 117.525 0.000 . 1 . . . . . 302 ILE N . 27670 1 405 . 1 1 306 306 ALA H H 1 7.625 0.000 . 1 . . . . . 303 ALA HN . 27670 1 406 . 1 1 306 306 ALA N N 15 118.948 0.000 . 1 . . . . . 303 ALA N . 27670 1 407 . 1 1 307 307 SER H H 1 7.489 0.000 . 1 . . . . . 304 SER HN . 27670 1 408 . 1 1 307 307 SER N N 15 110.865 0.000 . 1 . . . . . 304 SER N . 27670 1 409 . 1 1 308 308 LEU H H 1 8.103 0.000 . 1 . . . . . 305 LEU HN . 27670 1 410 . 1 1 308 308 LEU N N 15 118.836 0.000 . 1 . . . . . 305 LEU N . 27670 1 411 . 1 1 309 309 ASN H H 1 8.083 0.000 . 1 . . . . . 306 ASN HN . 27670 1 412 . 1 1 309 309 ASN N N 15 117.781 0.000 . 1 . . . . . 306 ASN N . 27670 1 413 . 1 1 310 310 GLY H H 1 8.600 0.000 . 1 . . . . . 307 GLY HN . 27670 1 414 . 1 1 310 310 GLY N N 15 117.533 0.000 . 1 . . . . . 307 GLY N . 27670 1 415 . 1 1 311 311 TYR H H 1 7.985 0.000 . 1 . . . . . 308 TYR HN . 27670 1 416 . 1 1 311 311 TYR N N 15 123.480 0.000 . 1 . . . . . 308 TYR N . 27670 1 417 . 1 1 312 312 ARG H H 1 7.608 0.000 . 1 . . . . . 309 ARG HN . 27670 1 418 . 1 1 312 312 ARG N N 15 127.455 0.000 . 1 . . . . . 309 ARG N . 27670 1 419 . 1 1 313 313 LEU H H 1 8.520 0.000 . 1 . . . . . 310 LEU HN . 27670 1 420 . 1 1 313 313 LEU N N 15 130.203 0.000 . 1 . . . . . 310 LEU N . 27670 1 421 . 1 1 314 314 GLY H H 1 9.004 0.000 . 1 . . . . . 311 GLY HN . 27670 1 422 . 1 1 314 314 GLY N N 15 118.391 0.000 . 1 . . . . . 311 GLY N . 27670 1 423 . 1 1 316 316 LYS H H 1 7.741 0.000 . 1 . . . . . 313 LYS HN . 27670 1 424 . 1 1 316 316 LYS N N 15 119.792 0.000 . 1 . . . . . 313 LYS N . 27670 1 425 . 1 1 317 317 ILE H H 1 8.131 0.000 . 1 . . . . . 314 ILE HN . 27670 1 426 . 1 1 317 317 ILE N N 15 120.993 0.000 . 1 . . . . . 314 ILE N . 27670 1 427 . 1 1 318 318 LEU H H 1 9.254 0.000 . 1 . . . . . 315 LEU HN . 27670 1 428 . 1 1 318 318 LEU N N 15 128.643 0.000 . 1 . . . . . 315 LEU N . 27670 1 429 . 1 1 319 319 GLN H H 1 8.187 0.000 . 1 . . . . . 316 GLN HN . 27670 1 430 . 1 1 319 319 GLN N N 15 121.816 0.000 . 1 . . . . . 316 GLN N . 27670 1 431 . 1 1 320 320 VAL H H 1 8.842 0.000 . 1 . . . . . 317 VAL HN . 27670 1 432 . 1 1 320 320 VAL N N 15 125.985 0.000 . 1 . . . . . 317 VAL N . 27670 1 433 . 1 1 321 321 SER H H 1 8.904 0.000 . 1 . . . . . 318 SER HN . 27670 1 434 . 1 1 321 321 SER N N 15 118.283 0.000 . 1 . . . . . 318 SER N . 27670 1 435 . 1 1 322 322 PHE H H 1 8.848 0.000 . 1 . . . . . 319 PHE HN . 27670 1 436 . 1 1 322 322 PHE N N 15 120.393 0.000 . 1 . . . . . 319 PHE N . 27670 1 437 . 1 1 323 323 LYS H H 1 9.035 0.000 . 1 . . . . . 320 LYS HN . 27670 1 438 . 1 1 323 323 LYS N N 15 123.517 0.000 . 1 . . . . . 320 LYS N . 27670 1 439 . 1 1 329 329 LYS H H 1 7.881 0.000 . 1 . . . . . 326 LYS HN . 27670 1 440 . 1 1 329 329 LYS N N 15 127.404 0.000 . 1 . . . . . 326 LYS N . 27670 1 stop_ save_