data_26318 ####################### # Entry information # ####################### save_entry_information_1 _Entry.Sf_category entry_information _Entry.Sf_framecode entry_information_1 _Entry.ID 26318 _Entry.Title ; Backbone 1H, 13C, 15N and CB Chemical Shift Assignments for RRM2/3 ; _Entry.Type macromolecule _Entry.Version_type original _Entry.Submission_date 2021-09-07 _Entry.Accession_date 2021-09-12 _Entry.Last_release_date 2021-09-12 _Entry.Original_release_date 2021-09-12 _Entry.Origination author _Entry.Format_name . _Entry.NMR_STAR_version 3.2.14.0 _Entry.NMR_STAR_dict_location . _Entry.Original_NMR_STAR_version 3.2.0.16 _Entry.Experimental_method NMR _Entry.Experimental_method_subtype solution _Entry.Source_data_format . _Entry.Source_data_format_version . _Entry.Generated_software_name . _Entry.Generated_software_version . _Entry.Generated_software_ID . _Entry.Generated_software_label . _Entry.Generated_date . _Entry.DOI . _Entry.UUID . _Entry.Related_coordinate_file_name . _Entry.Details . _Entry.BMRB_internal_directory_name . loop_ _Entry_author.Ordinal _Entry_author.Given_name _Entry_author.Family_name _Entry_author.First_initial _Entry_author.Middle_initials _Entry_author.Family_title _Entry_author.ORCID _Entry_author.Entry_ID 1 Takeru Sagae . . . . 26318 2 Mariko Yokogawa . . . . 26318 3 Masanori Osawa . . . . 26318 stop_ loop_ _Entry_src.ID _Entry_src.Project_name _Entry_src.Organization_full_name _Entry_src.Organization_initials _Entry_src.Entry_ID 1 . 'Keio University Faculty of Pharmacy Division of Physics for Life Functions' . 26318 stop_ loop_ _Data_set.Type _Data_set.Count _Data_set.Entry_ID assigned_chemical_shifts 1 26318 stop_ loop_ _Datum.Type _Datum.Count _Datum.Entry_ID '13C chemical shifts' 314 26318 '15N chemical shifts' 182 26318 '1H chemical shifts' 182 26318 stop_ loop_ _Release.Release_number _Release.Format_type _Release.Format_version _Release.Date _Release.Submission_date _Release.Type _Release.Author _Release.Detail _Release.Entry_ID 1 . . 2022-05-11 . original BMRB . 26318 stop_ loop_ _Related_entries.Database_name _Related_entries.Database_accession_code _Related_entries.Relationship _Related_entries.Entry_ID BMRB 26314 'Backbone 1H, 13C, 15N and Side chain CB Chemical Shift Assignments for Paip2A' 26318 BMRB 26315 'Backbone 1H, 15N and HA Chemical Shift Assignments for Paip2A(25-83)' 26318 BMRB 26316 'Backbone 1H, 13C, 15N, HA and Side chain 13C Chemical Shift Assignments for RRM2 of PABPC1' 26318 BMRB 26317 'Backbone 1H, 13C, 15N, HA and Side Chain 13C Chemical Shift Assignments for RRM3 of PABPC1' 26318 BMRB 26319 'Backbone 1H, 13C, 15N and CB Chemical Shift Assignments for RRM2/3 when in complex with 12mers of adenine' 26318 BMRB 26320 'Backbone 1H, 13C, and 15N Chemical Shift Assignments for RRM2/3 in complex with Paip2A(25-83)' 26318 BMRB 26323 'Backbone 1H, 13C, and 15N Chemical Shift Assignments for Paip2A(25-83) in complex with RRM2/3' 26318 BMRB 26326 'CA, CB, and CO Chemical Shift Assignments for Paip2A(25-83)' 26318 stop_ save_ ############### # Citations # ############### save_citations_1 _Citation.Sf_category citations _Citation.Sf_framecode citations_1 _Citation.Entry_ID 26318 _Citation.ID 1 _Citation.Name . _Citation.Class 'entry citation' _Citation.CAS_abstract_code . _Citation.MEDLINE_UI_code . _Citation.PubMed_ID 35307347 _Citation.DOI . _Citation.Full_citation . _Citation.Title ; Paip2 competitively dissociates PABPC1 from poly(A) by initial access to RRM2 of the poly(A)-bound PABPC1 ; _Citation.Status published _Citation.Type journal _Citation.Journal_abbrev 'J. Biol. Chem.' _Citation.Journal_name_full . _Citation.Journal_volume 298 _Citation.Journal_issue 5 _Citation.Journal_ASTM . _Citation.Journal_ISSN 1083-351X _Citation.Journal_CSD . _Citation.Book_title . _Citation.Book_chapter_title . _Citation.Book_volume . _Citation.Book_series . _Citation.Book_publisher . _Citation.Book_publisher_city . _Citation.Book_ISBN . _Citation.Conference_title . _Citation.Conference_site . _Citation.Conference_state_province . _Citation.Conference_country . _Citation.Conference_start_date . _Citation.Conference_end_date . _Citation.Conference_abstract_number . _Citation.Thesis_institution . _Citation.Thesis_institution_city . _Citation.Thesis_institution_country . _Citation.WWW_URL . _Citation.Page_first 101844 _Citation.Page_last 101844 _Citation.Year 2022 _Citation.Details . loop_ _Citation_author.Ordinal _Citation_author.Given_name _Citation_author.Family_name _Citation_author.First_initial _Citation_author.Middle_initials _Citation_author.Family_title _Citation_author.ORCID _Citation_author.Entry_ID _Citation_author.Citation_ID 1 Takeru Sagae . . . . 26318 1 2 Mariko Yokogawa . . . . 26318 1 3 Ryoichi Sawazaki . . . . 26318 1 4 Yuichiro Ishii . . . . 26318 1 5 Nao Hosoda . . . . 26318 1 6 Shin-ichi Hoshino . . . . 26318 1 7 Shunsuke Imai . . . . 26318 1 8 Ichio Shimada . . . . 26318 1 9 Masanori Osawa . . . . 26318 1 stop_ save_ ############################################# # Molecular system (assembly) description # ############################################# save_assembly_1 _Assembly.Sf_category assembly _Assembly.Sf_framecode assembly_1 _Assembly.Entry_ID 26318 _Assembly.ID 1 _Assembly.Name 'RRM2/3 of PABPC1 monomer' _Assembly.BMRB_code . _Assembly.Number_of_components 1 _Assembly.Organic_ligands 0 _Assembly.Metal_ions 0 _Assembly.Non_standard_bonds no _Assembly.Ambiguous_conformational_states no _Assembly.Ambiguous_chem_comp_sites . _Assembly.Molecules_in_chemical_exchange no _Assembly.Paramagnetic no _Assembly.Thiol_state . _Assembly.Molecular_mass 22202 _Assembly.Enzyme_commission_number . _Assembly.Details . _Assembly.DB_query_date . _Assembly.DB_query_revised_last_date . loop_ _Entity_assembly.ID _Entity_assembly.Entity_assembly_name _Entity_assembly.Entity_ID _Entity_assembly.Entity_label _Entity_assembly.Asym_ID _Entity_assembly.PDB_chain_ID _Entity_assembly.Experimental_data_reported _Entity_assembly.Physical_state _Entity_assembly.Conformational_isomer _Entity_assembly.Chemical_exchange_state _Entity_assembly.Magnetic_equivalence_group_code _Entity_assembly.Role _Entity_assembly.Details _Entity_assembly.Entry_ID _Entity_assembly.Assembly_ID 1 'subunit 1' 1 $entity_1 . . yes native no no . . . 26318 1 stop_ save_ #################################### # Biological polymers and ligands # #################################### save_entity_1 _Entity.Sf_category entity _Entity.Sf_framecode entity_1 _Entity.Entry_ID 26318 _Entity.ID 1 _Entity.BMRB_code . _Entity.Name 'RRM2/3 of PABPC1' _Entity.Type polymer _Entity.Polymer_common_type . _Entity.Polymer_type polypeptide(L) _Entity.Polymer_type_details . _Entity.Polymer_strand_ID . _Entity.Polymer_seq_one_letter_code_can . _Entity.Polymer_seq_one_letter_code ; GPLGSNIFIKNLDKSIDNKA LYDTFSAFGNILSCKVVCDE NGSKGYGFVHFETQEAAERA IEKMNGMLLNDRKVFVGRFK SRKEREAELGARAKEFTNVY IKNFGEDMDDERLKDLFGKF GPALSVKVMTDESGKSKGFG FVSFERHEDAQKAVDEMNGK ELNGKQIYVGRAQKKVERQT ELKRKFEQMKQDRIT ; _Entity.Target_identifier . _Entity.Polymer_author_defined_seq . _Entity.Polymer_author_seq_details . _Entity.Ambiguous_conformational_states no _Entity.Ambiguous_chem_comp_sites no _Entity.Nstd_monomer no _Entity.Nstd_chirality no _Entity.Nstd_linkage no _Entity.Nonpolymer_comp_ID . _Entity.Nonpolymer_comp_label . _Entity.Number_of_monomers 195 _Entity.Number_of_nonpolymer_components . _Entity.Paramagnetic no _Entity.Thiol_state 'all free' _Entity.Src_method . _Entity.Parent_entity_ID . _Entity.Fragment . _Entity.Mutation . _Entity.EC_number . _Entity.Calc_isoelectric_point . _Entity.Formula_weight 22202 _Entity.Formula_weight_exptl . _Entity.Formula_weight_exptl_meth . _Entity.Details . _Entity.DB_query_date . _Entity.DB_query_revised_last_date . loop_ _Entity_comp_index.ID _Entity_comp_index.Auth_seq_ID _Entity_comp_index.Comp_ID _Entity_comp_index.Comp_label _Entity_comp_index.Entry_ID _Entity_comp_index.Entity_ID 1 -5 GLY . 26318 1 2 -4 PRO . 26318 1 3 -3 LEU . 26318 1 4 -2 GLY . 26318 1 5 -1 SER . 26318 1 6 100 ASN . 26318 1 7 101 ILE . 26318 1 8 102 PHE . 26318 1 9 103 ILE . 26318 1 10 104 LYS . 26318 1 11 105 ASN . 26318 1 12 106 LEU . 26318 1 13 107 ASP . 26318 1 14 108 LYS . 26318 1 15 109 SER . 26318 1 16 110 ILE . 26318 1 17 111 ASP . 26318 1 18 112 ASN . 26318 1 19 113 LYS . 26318 1 20 114 ALA . 26318 1 21 115 LEU . 26318 1 22 116 TYR . 26318 1 23 117 ASP . 26318 1 24 118 THR . 26318 1 25 119 PHE . 26318 1 26 120 SER . 26318 1 27 121 ALA . 26318 1 28 122 PHE . 26318 1 29 123 GLY . 26318 1 30 124 ASN . 26318 1 31 125 ILE . 26318 1 32 126 LEU . 26318 1 33 127 SER . 26318 1 34 128 CYS . 26318 1 35 129 LYS . 26318 1 36 130 VAL . 26318 1 37 131 VAL . 26318 1 38 132 CYS . 26318 1 39 133 ASP . 26318 1 40 134 GLU . 26318 1 41 135 ASN . 26318 1 42 136 GLY . 26318 1 43 137 SER . 26318 1 44 138 LYS . 26318 1 45 139 GLY . 26318 1 46 140 TYR . 26318 1 47 141 GLY . 26318 1 48 142 PHE . 26318 1 49 143 VAL . 26318 1 50 144 HIS . 26318 1 51 145 PHE . 26318 1 52 146 GLU . 26318 1 53 147 THR . 26318 1 54 148 GLN . 26318 1 55 149 GLU . 26318 1 56 150 ALA . 26318 1 57 151 ALA . 26318 1 58 152 GLU . 26318 1 59 153 ARG . 26318 1 60 154 ALA . 26318 1 61 155 ILE . 26318 1 62 156 GLU . 26318 1 63 157 LYS . 26318 1 64 158 MET . 26318 1 65 159 ASN . 26318 1 66 160 GLY . 26318 1 67 161 MET . 26318 1 68 162 LEU . 26318 1 69 163 LEU . 26318 1 70 164 ASN . 26318 1 71 165 ASP . 26318 1 72 166 ARG . 26318 1 73 167 LYS . 26318 1 74 168 VAL . 26318 1 75 169 PHE . 26318 1 76 170 VAL . 26318 1 77 171 GLY . 26318 1 78 172 ARG . 26318 1 79 173 PHE . 26318 1 80 174 LYS . 26318 1 81 175 SER . 26318 1 82 176 ARG . 26318 1 83 177 LYS . 26318 1 84 178 GLU . 26318 1 85 179 ARG . 26318 1 86 180 GLU . 26318 1 87 181 ALA . 26318 1 88 182 GLU . 26318 1 89 183 LEU . 26318 1 90 184 GLY . 26318 1 91 185 ALA . 26318 1 92 186 ARG . 26318 1 93 187 ALA . 26318 1 94 188 LYS . 26318 1 95 189 GLU . 26318 1 96 190 PHE . 26318 1 97 191 THR . 26318 1 98 192 ASN . 26318 1 99 193 VAL . 26318 1 100 194 TYR . 26318 1 101 195 ILE . 26318 1 102 196 LYS . 26318 1 103 197 ASN . 26318 1 104 198 PHE . 26318 1 105 199 GLY . 26318 1 106 200 GLU . 26318 1 107 201 ASP . 26318 1 108 202 MET . 26318 1 109 203 ASP . 26318 1 110 204 ASP . 26318 1 111 205 GLU . 26318 1 112 206 ARG . 26318 1 113 207 LEU . 26318 1 114 208 LYS . 26318 1 115 209 ASP . 26318 1 116 210 LEU . 26318 1 117 211 PHE . 26318 1 118 212 GLY . 26318 1 119 213 LYS . 26318 1 120 214 PHE . 26318 1 121 215 GLY . 26318 1 122 216 PRO . 26318 1 123 217 ALA . 26318 1 124 218 LEU . 26318 1 125 219 SER . 26318 1 126 220 VAL . 26318 1 127 221 LYS . 26318 1 128 222 VAL . 26318 1 129 223 MET . 26318 1 130 224 THR . 26318 1 131 225 ASP . 26318 1 132 226 GLU . 26318 1 133 227 SER . 26318 1 134 228 GLY . 26318 1 135 229 LYS . 26318 1 136 230 SER . 26318 1 137 231 LYS . 26318 1 138 232 GLY . 26318 1 139 233 PHE . 26318 1 140 234 GLY . 26318 1 141 235 PHE . 26318 1 142 236 VAL . 26318 1 143 237 SER . 26318 1 144 238 PHE . 26318 1 145 239 GLU . 26318 1 146 240 ARG . 26318 1 147 241 HIS . 26318 1 148 242 GLU . 26318 1 149 243 ASP . 26318 1 150 244 ALA . 26318 1 151 245 GLN . 26318 1 152 246 LYS . 26318 1 153 247 ALA . 26318 1 154 248 VAL . 26318 1 155 249 ASP . 26318 1 156 250 GLU . 26318 1 157 251 MET . 26318 1 158 252 ASN . 26318 1 159 253 GLY . 26318 1 160 254 LYS . 26318 1 161 255 GLU . 26318 1 162 256 LEU . 26318 1 163 257 ASN . 26318 1 164 258 GLY . 26318 1 165 259 LYS . 26318 1 166 260 GLN . 26318 1 167 261 ILE . 26318 1 168 262 TYR . 26318 1 169 263 VAL . 26318 1 170 264 GLY . 26318 1 171 265 ARG . 26318 1 172 266 ALA . 26318 1 173 267 GLN . 26318 1 174 268 LYS . 26318 1 175 269 LYS . 26318 1 176 270 VAL . 26318 1 177 271 GLU . 26318 1 178 272 ARG . 26318 1 179 273 GLN . 26318 1 180 274 THR . 26318 1 181 275 GLU . 26318 1 182 276 LEU . 26318 1 183 277 LYS . 26318 1 184 278 ARG . 26318 1 185 279 LYS . 26318 1 186 280 PHE . 26318 1 187 281 GLU . 26318 1 188 282 GLN . 26318 1 189 283 MET . 26318 1 190 284 LYS . 26318 1 191 285 GLN . 26318 1 192 286 ASP . 26318 1 193 287 ARG . 26318 1 194 288 ILE . 26318 1 195 289 THR . 26318 1 stop_ loop_ _Entity_poly_seq.Hetero _Entity_poly_seq.Mon_ID _Entity_poly_seq.Num _Entity_poly_seq.Comp_index_ID _Entity_poly_seq.Entry_ID _Entity_poly_seq.Entity_ID . GLY 1 1 26318 1 . PRO 2 2 26318 1 . LEU 3 3 26318 1 . GLY 4 4 26318 1 . SER 5 5 26318 1 . ASN 6 6 26318 1 . ILE 7 7 26318 1 . PHE 8 8 26318 1 . ILE 9 9 26318 1 . LYS 10 10 26318 1 . ASN 11 11 26318 1 . LEU 12 12 26318 1 . ASP 13 13 26318 1 . LYS 14 14 26318 1 . SER 15 15 26318 1 . ILE 16 16 26318 1 . ASP 17 17 26318 1 . ASN 18 18 26318 1 . LYS 19 19 26318 1 . ALA 20 20 26318 1 . LEU 21 21 26318 1 . TYR 22 22 26318 1 . ASP 23 23 26318 1 . THR 24 24 26318 1 . PHE 25 25 26318 1 . SER 26 26 26318 1 . ALA 27 27 26318 1 . PHE 28 28 26318 1 . GLY 29 29 26318 1 . ASN 30 30 26318 1 . ILE 31 31 26318 1 . LEU 32 32 26318 1 . SER 33 33 26318 1 . CYS 34 34 26318 1 . LYS 35 35 26318 1 . VAL 36 36 26318 1 . VAL 37 37 26318 1 . CYS 38 38 26318 1 . ASP 39 39 26318 1 . GLU 40 40 26318 1 . ASN 41 41 26318 1 . GLY 42 42 26318 1 . SER 43 43 26318 1 . LYS 44 44 26318 1 . GLY 45 45 26318 1 . TYR 46 46 26318 1 . GLY 47 47 26318 1 . PHE 48 48 26318 1 . VAL 49 49 26318 1 . HIS 50 50 26318 1 . PHE 51 51 26318 1 . GLU 52 52 26318 1 . THR 53 53 26318 1 . GLN 54 54 26318 1 . GLU 55 55 26318 1 . ALA 56 56 26318 1 . ALA 57 57 26318 1 . GLU 58 58 26318 1 . ARG 59 59 26318 1 . ALA 60 60 26318 1 . ILE 61 61 26318 1 . GLU 62 62 26318 1 . LYS 63 63 26318 1 . MET 64 64 26318 1 . ASN 65 65 26318 1 . GLY 66 66 26318 1 . MET 67 67 26318 1 . LEU 68 68 26318 1 . LEU 69 69 26318 1 . ASN 70 70 26318 1 . ASP 71 71 26318 1 . ARG 72 72 26318 1 . LYS 73 73 26318 1 . VAL 74 74 26318 1 . PHE 75 75 26318 1 . VAL 76 76 26318 1 . GLY 77 77 26318 1 . ARG 78 78 26318 1 . PHE 79 79 26318 1 . LYS 80 80 26318 1 . SER 81 81 26318 1 . ARG 82 82 26318 1 . LYS 83 83 26318 1 . GLU 84 84 26318 1 . ARG 85 85 26318 1 . GLU 86 86 26318 1 . ALA 87 87 26318 1 . GLU 88 88 26318 1 . LEU 89 89 26318 1 . GLY 90 90 26318 1 . ALA 91 91 26318 1 . ARG 92 92 26318 1 . ALA 93 93 26318 1 . LYS 94 94 26318 1 . GLU 95 95 26318 1 . PHE 96 96 26318 1 . THR 97 97 26318 1 . ASN 98 98 26318 1 . VAL 99 99 26318 1 . TYR 100 100 26318 1 . ILE 101 101 26318 1 . LYS 102 102 26318 1 . ASN 103 103 26318 1 . PHE 104 104 26318 1 . GLY 105 105 26318 1 . GLU 106 106 26318 1 . ASP 107 107 26318 1 . MET 108 108 26318 1 . ASP 109 109 26318 1 . ASP 110 110 26318 1 . GLU 111 111 26318 1 . ARG 112 112 26318 1 . LEU 113 113 26318 1 . LYS 114 114 26318 1 . ASP 115 115 26318 1 . LEU 116 116 26318 1 . PHE 117 117 26318 1 . GLY 118 118 26318 1 . LYS 119 119 26318 1 . PHE 120 120 26318 1 . GLY 121 121 26318 1 . PRO 122 122 26318 1 . ALA 123 123 26318 1 . LEU 124 124 26318 1 . SER 125 125 26318 1 . VAL 126 126 26318 1 . LYS 127 127 26318 1 . VAL 128 128 26318 1 . MET 129 129 26318 1 . THR 130 130 26318 1 . ASP 131 131 26318 1 . GLU 132 132 26318 1 . SER 133 133 26318 1 . GLY 134 134 26318 1 . LYS 135 135 26318 1 . SER 136 136 26318 1 . LYS 137 137 26318 1 . GLY 138 138 26318 1 . PHE 139 139 26318 1 . GLY 140 140 26318 1 . PHE 141 141 26318 1 . VAL 142 142 26318 1 . SER 143 143 26318 1 . PHE 144 144 26318 1 . GLU 145 145 26318 1 . ARG 146 146 26318 1 . HIS 147 147 26318 1 . GLU 148 148 26318 1 . ASP 149 149 26318 1 . ALA 150 150 26318 1 . GLN 151 151 26318 1 . LYS 152 152 26318 1 . ALA 153 153 26318 1 . VAL 154 154 26318 1 . ASP 155 155 26318 1 . GLU 156 156 26318 1 . MET 157 157 26318 1 . ASN 158 158 26318 1 . GLY 159 159 26318 1 . LYS 160 160 26318 1 . GLU 161 161 26318 1 . LEU 162 162 26318 1 . ASN 163 163 26318 1 . GLY 164 164 26318 1 . LYS 165 165 26318 1 . GLN 166 166 26318 1 . ILE 167 167 26318 1 . TYR 168 168 26318 1 . VAL 169 169 26318 1 . GLY 170 170 26318 1 . ARG 171 171 26318 1 . ALA 172 172 26318 1 . GLN 173 173 26318 1 . LYS 174 174 26318 1 . LYS 175 175 26318 1 . VAL 176 176 26318 1 . GLU 177 177 26318 1 . ARG 178 178 26318 1 . GLN 179 179 26318 1 . THR 180 180 26318 1 . GLU 181 181 26318 1 . LEU 182 182 26318 1 . LYS 183 183 26318 1 . ARG 184 184 26318 1 . LYS 185 185 26318 1 . PHE 186 186 26318 1 . GLU 187 187 26318 1 . GLN 188 188 26318 1 . MET 189 189 26318 1 . LYS 190 190 26318 1 . GLN 191 191 26318 1 . ASP 192 192 26318 1 . ARG 193 193 26318 1 . ILE 194 194 26318 1 . THR 195 195 26318 1 stop_ save_ #################### # Natural source # #################### save_natural_source_1 _Entity_natural_src_list.Sf_category natural_source _Entity_natural_src_list.Sf_framecode natural_source_1 _Entity_natural_src_list.Entry_ID 26318 _Entity_natural_src_list.ID 1 loop_ _Entity_natural_src.ID _Entity_natural_src.Entity_ID _Entity_natural_src.Entity_label _Entity_natural_src.Entity_chimera_segment_ID _Entity_natural_src.NCBI_taxonomy_ID _Entity_natural_src.Type _Entity_natural_src.Common _Entity_natural_src.Organism_name_scientific _Entity_natural_src.Organism_name_common _Entity_natural_src.Organism_acronym _Entity_natural_src.ICTVdb_decimal_code _Entity_natural_src.Superkingdom _Entity_natural_src.Kingdom _Entity_natural_src.Genus _Entity_natural_src.Species _Entity_natural_src.Strain _Entity_natural_src.Variant _Entity_natural_src.Organ _Entity_natural_src.Tissue _Entity_natural_src.Tissue_fraction _Entity_natural_src.Cell_line _Entity_natural_src.Cell_type _Entity_natural_src.ATCC_number _Entity_natural_src.Organelle _Entity_natural_src.Secretion _Entity_natural_src.Plasmid _Entity_natural_src.Gene_mnemonic _Entity_natural_src.Details _Entity_natural_src.Entry_ID _Entity_natural_src.Entity_natural_src_list_ID 1 1 $entity_1 . 562 organism . 'Escherichia coli' 'E. coli' . . Bacteria . Escherichia coli . . . . . . . . . . . . . 26318 1 stop_ save_ ######################### # Experimental source # ######################### save_experimental_source_1 _Entity_experimental_src_list.Sf_category experimental_source _Entity_experimental_src_list.Sf_framecode experimental_source_1 _Entity_experimental_src_list.Entry_ID 26318 _Entity_experimental_src_list.ID 1 loop_ _Entity_experimental_src.ID _Entity_experimental_src.Entity_ID _Entity_experimental_src.Entity_label _Entity_experimental_src.Entity_chimera_segment_ID _Entity_experimental_src.Production_method _Entity_experimental_src.Host_org_scientific_name _Entity_experimental_src.Host_org_name_common _Entity_experimental_src.Host_org_details _Entity_experimental_src.Host_org_NCBI_taxonomy_ID _Entity_experimental_src.Host_org_genus _Entity_experimental_src.Host_org_species _Entity_experimental_src.Host_org_strain _Entity_experimental_src.Host_org_variant _Entity_experimental_src.Host_org_ATCC_number _Entity_experimental_src.Vector_type _Entity_experimental_src.PDBview_host_org_vector_name _Entity_experimental_src.PDBview_plasmid_name _Entity_experimental_src.Vector_name _Entity_experimental_src.Vector_details _Entity_experimental_src.Vendor_name _Entity_experimental_src.Details _Entity_experimental_src.Entry_ID _Entity_experimental_src.Entity_experimental_src_list_ID 1 1 $entity_1 . 'recombinant technology' 'Escherichia coli' . . 562 . . . . . plasmid . . pGEX-6p-1 . . . 26318 1 stop_ save_ ##################################### # Sample contents and methodology # ##################################### ######################## # Sample description # ######################## save_sample_1 _Sample.Sf_category sample _Sample.Sf_framecode sample_1 _Sample.Entry_ID 26318 _Sample.ID 1 _Sample.Name 'RRM2/3 of PABPC1' _Sample.Type solution _Sample.Sub_type . _Sample.Details . _Sample.Aggregate_sample_number 1 _Sample.Solvent_system '90% H2O/10% D2O' _Sample.Preparation_date . _Sample.Preparation_expiration_date . _Sample.Polycrystallization_protocol . _Sample.Single_crystal_protocol . _Sample.Crystal_grow_apparatus . _Sample.Crystal_grow_atmosphere . _Sample.Crystal_grow_details . _Sample.Crystal_grow_method . _Sample.Crystal_grow_method_cit_ID . _Sample.Crystal_grow_pH . _Sample.Crystal_grow_pH_range . _Sample.Crystal_grow_pressure . _Sample.Crystal_grow_pressure_esd . _Sample.Crystal_grow_seeding . _Sample.Crystal_grow_seeding_cit_ID . _Sample.Crystal_grow_temp . _Sample.Crystal_grow_temp_details . _Sample.Crystal_grow_temp_esd . _Sample.Crystal_grow_time . _Sample.Oriented_sample_prep_protocol . _Sample.Lyophilization_cryo_protectant . _Sample.Storage_protocol . loop_ _Sample_component.ID _Sample_component.Mol_common_name _Sample_component.Isotopic_labeling _Sample_component.Assembly_ID _Sample_component.Assembly_label _Sample_component.Entity_ID _Sample_component.Entity_label _Sample_component.Product_ID _Sample_component.Type _Sample_component.Concentration_val _Sample_component.Concentration_val_min _Sample_component.Concentration_val_max _Sample_component.Concentration_val_units _Sample_component.Concentration_val_err _Sample_component.Vendor _Sample_component.Vendor_product_name _Sample_component.Vendor_product_code _Sample_component.Entry_ID _Sample_component.Sample_ID 1 'RRM2/3 of PABPC1' '[U-100% 13C; U-100% 15N]' 1 $assembly_1 1 $entity_1 . protein 507 . . uM . . . . 26318 1 2 'sodium phosphate' 'natural abundance' . . . . . buffer 18 . . mM . . . . 26318 1 3 'sodium chloride' 'natural abundance' . . . . . salt 135 . . mM . . . . 26318 1 4 H2O 'natural abundance' . . . . . solvent 90 . . % . . . . 26318 1 5 D2O [U-2H] . . . . . solvent 10 . . % . . . . 26318 1 6 DTT 'natural abundance' . . . . . . 0.9 . . mM . . . . 26318 1 stop_ save_ ####################### # Sample conditions # ####################### save_sample_conditions_1 _Sample_condition_list.Sf_category sample_conditions _Sample_condition_list.Sf_framecode sample_conditions_1 _Sample_condition_list.Entry_ID 26318 _Sample_condition_list.ID 1 _Sample_condition_list.Name 'Phosphate buffer' _Sample_condition_list.Details . loop_ _Sample_condition_variable.Type _Sample_condition_variable.Val _Sample_condition_variable.Val_err _Sample_condition_variable.Val_units _Sample_condition_variable.Entry_ID _Sample_condition_variable.Sample_condition_list_ID pH 6.5 . pH 26318 1 pressure 1 . atm 26318 1 temperature 303 . K 26318 1 stop_ save_ ############################ # Computer software used # ############################ save_software_1 _Software.Sf_category software _Software.Sf_framecode software_1 _Software.Entry_ID 26318 _Software.ID 1 _Software.Type . _Software.Name SPARKY _Software.Version . _Software.DOI . _Software.Details . loop_ _Task.Task _Task.Software_module _Task.Entry_ID _Task.Software_ID 'chemical shift assignment' . 26318 1 stop_ save_ ######################### # Experimental detail # ######################### ################################## # NMR Spectrometer definitions # ################################## save_NMR_spectrometer_1 _NMR_spectrometer.Sf_category NMR_spectrometer _NMR_spectrometer.Sf_framecode NMR_spectrometer_1 _NMR_spectrometer.Entry_ID 26318 _NMR_spectrometer.ID 1 _NMR_spectrometer.Name 'Bruker AVANCE NEO 600' _NMR_spectrometer.Details . _NMR_spectrometer.Manufacturer Bruker _NMR_spectrometer.Model 'AVANCE NEO' _NMR_spectrometer.Serial_number . _NMR_spectrometer.Field_strength 600 save_ ############################# # NMR applied experiments # ############################# save_experiment_list_1 _Experiment_list.Sf_category experiment_list _Experiment_list.Sf_framecode experiment_list_1 _Experiment_list.Entry_ID 26318 _Experiment_list.ID 1 _Experiment_list.Details . loop_ _Experiment.ID _Experiment.Name _Experiment.Raw_data_flag _Experiment.NUS_flag _Experiment.Interleaved_flag _Experiment.NMR_spec_expt_ID _Experiment.NMR_spec_expt_label _Experiment.MS_expt_ID _Experiment.MS_expt_label _Experiment.SAXS_expt_ID _Experiment.SAXS_expt_label _Experiment.FRET_expt_ID _Experiment.FRET_expt_label _Experiment.EMR_expt_ID _Experiment.EMR_expt_label _Experiment.Sample_ID _Experiment.Sample_label _Experiment.Sample_state _Experiment.Sample_volume _Experiment.Sample_volume_units _Experiment.Sample_condition_list_ID _Experiment.Sample_condition_list_label _Experiment.Sample_spinning_rate _Experiment.Sample_angle _Experiment.NMR_tube_type _Experiment.NMR_spectrometer_ID _Experiment.NMR_spectrometer_label _Experiment.NMR_spectrometer_probe_ID _Experiment.NMR_spectrometer_probe_label _Experiment.NMR_spectral_processing_ID _Experiment.NMR_spectral_processing_label _Experiment.Mass_spectrometer_ID _Experiment.Mass_spectrometer_label _Experiment.Xray_instrument_ID _Experiment.Xray_instrument_label _Experiment.Fluorescence_instrument_ID _Experiment.Fluorescence_instrument_label _Experiment.EMR_instrument_ID _Experiment.EMR_instrument_label _Experiment.Chromatographic_system_ID _Experiment.Chromatographic_system_label _Experiment.Chromatographic_column_ID _Experiment.Chromatographic_column_label _Experiment.Details _Experiment.Entry_ID _Experiment.Experiment_list_ID 1 '2D 1H-15N HSQC' no no . . . . . . . . . . . 1 $sample_1 isotropic . . 1 $sample_conditions_1 . . . 1 $NMR_spectrometer_1 . . . . . . . . . . . . . . . . . 26318 1 2 '3D CBCA(CO)NH' no yes . . . . . . . . . . . 1 $sample_1 isotropic . . 1 $sample_conditions_1 . . . 1 $NMR_spectrometer_1 . . . . . . . . . . . . . . . . . 26318 1 3 '3D HNCA' no yes . . . . . . . . . . . 1 $sample_1 isotropic . . 1 $sample_conditions_1 . . . 1 $NMR_spectrometer_1 . . . . . . . . . . . . . . . . . 26318 1 4 '3D HNCACB' no yes . . . . . . . . . . . 1 $sample_1 isotropic . . 1 $sample_conditions_1 . . . 1 $NMR_spectrometer_1 . . . . . . . . . . . . . . . . . 26318 1 5 '3D HN(CO)CA' no yes . . . . . . . . . . . 1 $sample_1 isotropic . . 1 $sample_conditions_1 . . . 1 $NMR_spectrometer_1 . . . . . . . . . . . . . . . . . 26318 1 stop_ save_ #################### # NMR parameters # #################### ############################## # Assigned chemical shifts # ############################## ################################ # Chemical shift referencing # ################################ save_chem_shift_reference_1 _Chem_shift_reference.Sf_category chem_shift_reference _Chem_shift_reference.Sf_framecode chem_shift_reference_1 _Chem_shift_reference.Entry_ID 26318 _Chem_shift_reference.ID 1 _Chem_shift_reference.Name DSS _Chem_shift_reference.Details . loop_ _Chem_shift_ref.Atom_type _Chem_shift_ref.Atom_isotope_number _Chem_shift_ref.Mol_common_name _Chem_shift_ref.Atom_group _Chem_shift_ref.Concentration_val _Chem_shift_ref.Concentration_units _Chem_shift_ref.Solvent _Chem_shift_ref.Rank _Chem_shift_ref.Chem_shift_units _Chem_shift_ref.Chem_shift_val _Chem_shift_ref.Ref_method _Chem_shift_ref.Ref_type _Chem_shift_ref.Indirect_shift_ratio _Chem_shift_ref.External_ref_loc _Chem_shift_ref.External_ref_sample_geometry _Chem_shift_ref.External_ref_axis _Chem_shift_ref.Ref_correction_type _Chem_shift_ref.Correction_val _Chem_shift_ref.Entry_ID _Chem_shift_ref.Chem_shift_reference_ID C 13 DSS 'methyl protons' . . . . ppm 0 external indirect 0.251449530 . . . . . 26318 1 H 1 DSS 'methyl protons' . . . . ppm 0 external direct 1 . . . . . 26318 1 N 15 DSS 'methyl protons' . . . . ppm 0 external indirect 0.101329118 . . . . . 26318 1 stop_ save_ ################################### # Assigned chemical shift lists # ################################### ################################################################### # Chemical Shift Ambiguity Index Value Definitions # # # # The values other than 1 are used for those atoms with different # # chemical shifts that cannot be assigned to stereospecific atoms # # or to specific residues or chains. # # # # Index Value Definition # # # # 1 Unique (including isolated methyl protons, # # geminal atoms, and geminal methyl # # groups with identical chemical shifts) # # (e.g. ILE HD11, HD12, HD13 protons) # # 2 Ambiguity of geminal atoms or geminal methyl # # proton groups (e.g. ASP HB2 and HB3 # # protons, LEU CD1 and CD2 carbons, or # # LEU HD11, HD12, HD13 and HD21, HD22, # # HD23 methyl protons) # # 3 Aromatic atoms on opposite sides of # # symmetrical rings (e.g. TYR HE1 and HE2 # # protons) # # 4 Intraresidue ambiguities (e.g. LYS HG and # # HD protons or TRP HZ2 and HZ3 protons) # # 5 Interresidue ambiguities (LYS 12 vs. LYS 27) # # 6 Intermolecular ambiguities (e.g. ASP 31 CA # # in monomer 1 and ASP 31 CA in monomer 2 # # of an asymmetrical homodimer, duplex # # DNA assignments, or other assignments # # that may apply to atoms in one or more # # molecule in the molecular assembly) # # 9 Ambiguous, specific ambiguity not defined # # # ################################################################### save_assigned_chemical_shifts_1 _Assigned_chem_shift_list.Sf_category assigned_chemical_shifts _Assigned_chem_shift_list.Sf_framecode assigned_chemical_shifts_1 _Assigned_chem_shift_list.Entry_ID 26318 _Assigned_chem_shift_list.ID 1 _Assigned_chem_shift_list.Name 'Assigned chemical shift of RRM2/3 of PABPC1' _Assigned_chem_shift_list.Sample_condition_list_ID 1 _Assigned_chem_shift_list.Sample_condition_list_label $sample_conditions_1 _Assigned_chem_shift_list.Chem_shift_reference_ID 1 _Assigned_chem_shift_list.Chem_shift_reference_label $chem_shift_reference_1 _Assigned_chem_shift_list.Chem_shift_1H_err . _Assigned_chem_shift_list.Chem_shift_13C_err . _Assigned_chem_shift_list.Chem_shift_15N_err . _Assigned_chem_shift_list.Chem_shift_31P_err . _Assigned_chem_shift_list.Chem_shift_2H_err . _Assigned_chem_shift_list.Chem_shift_19F_err . _Assigned_chem_shift_list.Error_derivation_method . _Assigned_chem_shift_list.Details . _Assigned_chem_shift_list.Text_data_format . _Assigned_chem_shift_list.Text_data . loop_ _Chem_shift_experiment.Experiment_ID _Chem_shift_experiment.Experiment_name _Chem_shift_experiment.Sample_ID _Chem_shift_experiment.Sample_label _Chem_shift_experiment.Sample_state _Chem_shift_experiment.Entry_ID _Chem_shift_experiment.Assigned_chem_shift_list_ID 1 '2D 1H-15N HSQC' 1 $sample_1 isotropic 26318 1 2 '3D CBCA(CO)NH' 1 $sample_1 isotropic 26318 1 3 '3D HNCA' 1 $sample_1 isotropic 26318 1 4 '3D HNCACB' 1 $sample_1 isotropic 26318 1 5 '3D HN(CO)CA' 1 $sample_1 isotropic 26318 1 stop_ loop_ _Chem_shift_software.Software_ID _Chem_shift_software.Software_label _Chem_shift_software.Method_ID _Chem_shift_software.Method_label _Chem_shift_software.Entry_ID _Chem_shift_software.Assigned_chem_shift_list_ID 1 $software_1 . . 26318 1 stop_ loop_ _Atom_chem_shift.ID _Atom_chem_shift.Assembly_atom_ID _Atom_chem_shift.Entity_assembly_ID _Atom_chem_shift.Entity_assembly_asym_ID _Atom_chem_shift.Entity_ID _Atom_chem_shift.Comp_index_ID _Atom_chem_shift.Seq_ID _Atom_chem_shift.Comp_ID _Atom_chem_shift.Atom_ID _Atom_chem_shift.Atom_type _Atom_chem_shift.Atom_isotope_number _Atom_chem_shift.Val _Atom_chem_shift.Val_err _Atom_chem_shift.Assign_fig_of_merit _Atom_chem_shift.Ambiguity_code _Atom_chem_shift.Ambiguity_set_ID _Atom_chem_shift.Occupancy _Atom_chem_shift.Resonance_ID _Atom_chem_shift.Auth_entity_assembly_ID _Atom_chem_shift.Auth_asym_ID _Atom_chem_shift.Auth_seq_ID _Atom_chem_shift.Auth_comp_ID _Atom_chem_shift.Auth_atom_ID _Atom_chem_shift.Details _Atom_chem_shift.Entry_ID _Atom_chem_shift.Assigned_chem_shift_list_ID 1 . 1 . 1 2 2 PRO CA C 13 63.257 0.090 . 1 . . . . . -4 PRO CA . 26318 1 2 . 1 . 1 2 2 PRO CB C 13 32.404 0.000 . 1 . . . . . -4 PRO CB . 26318 1 3 . 1 . 1 3 3 LEU H H 1 8.497 0.004 . 1 . . . . . -3 LEU H . 26318 1 4 . 1 . 1 3 3 LEU CA C 13 55.713 0.097 . 1 . . . . . -3 LEU CA . 26318 1 5 . 1 . 1 3 3 LEU CB C 13 42.705 0.002 . 1 . . . . . -3 LEU CB . 26318 1 6 . 1 . 1 3 3 LEU N N 15 122.463 0.051 . 1 . . . . . -3 LEU N . 26318 1 7 . 1 . 1 4 4 GLY H H 1 8.408 0.003 . 1 . . . . . -2 GLY H . 26318 1 8 . 1 . 1 4 4 GLY CA C 13 45.697 0.070 . 1 . . . . . -2 GLY CA . 26318 1 9 . 1 . 1 4 4 GLY N N 15 108.787 0.024 . 1 . . . . . -2 GLY N . 26318 1 10 . 1 . 1 5 5 SER H H 1 8.341 0.003 . 1 . . . . . -1 SER H . 26318 1 11 . 1 . 1 5 5 SER CA C 13 58.138 0.089 . 1 . . . . . -1 SER CA . 26318 1 12 . 1 . 1 5 5 SER CB C 13 64.587 0.067 . 1 . . . . . -1 SER CB . 26318 1 13 . 1 . 1 5 5 SER N N 15 113.69 0.043 . 1 . . . . . -1 SER N . 26318 1 14 . 1 . 1 6 6 ASN H H 1 8.433 0.005 . 1 . . . . . 100 ASN H . 26318 1 15 . 1 . 1 6 6 ASN CA C 13 52.64 0.069 . 1 . . . . . 100 ASN CA . 26318 1 16 . 1 . 1 6 6 ASN CB C 13 41.087 0.020 . 1 . . . . . 100 ASN CB . 26318 1 17 . 1 . 1 6 6 ASN N N 15 122.257 0.013 . 1 . . . . . 100 ASN N . 26318 1 18 . 1 . 1 7 7 ILE H H 1 9.143 0.006 . 1 . . . . . 101 ILE H . 26318 1 19 . 1 . 1 7 7 ILE CA C 13 59.357 0.140 . 1 . . . . . 101 ILE CA . 26318 1 20 . 1 . 1 7 7 ILE N N 15 116.627 0.061 . 1 . . . . . 101 ILE N . 26318 1 21 . 1 . 1 8 8 PHE H H 1 8.871 0.007 . 1 . . . . . 102 PHE H . 26318 1 22 . 1 . 1 8 8 PHE CA C 13 54.902 0.072 . 1 . . . . . 102 PHE CA . 26318 1 23 . 1 . 1 8 8 PHE CB C 13 42.778 0.004 . 1 . . . . . 102 PHE CB . 26318 1 24 . 1 . 1 8 8 PHE N N 15 121.45 0.023 . 1 . . . . . 102 PHE N . 26318 1 25 . 1 . 1 9 9 ILE H H 1 8.436 0.004 . 1 . . . . . 103 ILE H . 26318 1 26 . 1 . 1 9 9 ILE CA C 13 59.604 0.085 . 1 . . . . . 103 ILE CA . 26318 1 27 . 1 . 1 9 9 ILE CB C 13 41.751 0.000 . 1 . . . . . 103 ILE CB . 26318 1 28 . 1 . 1 9 9 ILE N N 15 122.811 0.047 . 1 . . . . . 103 ILE N . 26318 1 29 . 1 . 1 10 10 LYS H H 1 9.228 0.003 . 1 . . . . . 104 LYS H . 26318 1 30 . 1 . 1 10 10 LYS CA C 13 54.963 0.131 . 1 . . . . . 104 LYS CA . 26318 1 31 . 1 . 1 10 10 LYS CB C 13 36.489 0.000 . 1 . . . . . 104 LYS CB . 26318 1 32 . 1 . 1 10 10 LYS N N 15 123.575 0.053 . 1 . . . . . 104 LYS N . 26318 1 33 . 1 . 1 11 11 ASN H H 1 8.475 0.003 . 1 . . . . . 105 ASN H . 26318 1 34 . 1 . 1 11 11 ASN CA C 13 54.117 0.072 . 1 . . . . . 105 ASN CA . 26318 1 35 . 1 . 1 11 11 ASN CB C 13 37.927 0.000 . 1 . . . . . 105 ASN CB . 26318 1 36 . 1 . 1 11 11 ASN N N 15 116.966 0.034 . 1 . . . . . 105 ASN N . 26318 1 37 . 1 . 1 12 12 LEU H H 1 7.888 0.007 . 1 . . . . . 106 LEU H . 26318 1 38 . 1 . 1 12 12 LEU CA C 13 53.886 0.062 . 1 . . . . . 106 LEU CA . 26318 1 39 . 1 . 1 12 12 LEU CB C 13 43.714 0.002 . 1 . . . . . 106 LEU CB . 26318 1 40 . 1 . 1 12 12 LEU N N 15 115.904 0.031 . 1 . . . . . 106 LEU N . 26318 1 41 . 1 . 1 13 13 ASP H H 1 8.66 0.007 . 1 . . . . . 107 ASP H . 26318 1 42 . 1 . 1 13 13 ASP CA C 13 54.962 0.092 . 1 . . . . . 107 ASP CA . 26318 1 43 . 1 . 1 13 13 ASP CB C 13 43.638 0.000 . 1 . . . . . 107 ASP CB . 26318 1 44 . 1 . 1 13 13 ASP N N 15 123.507 0.047 . 1 . . . . . 107 ASP N . 26318 1 45 . 1 . 1 14 14 LYS H H 1 8.696 0.003 . 1 . . . . . 108 LYS H . 26318 1 46 . 1 . 1 14 14 LYS CA C 13 59.203 0.067 . 1 . . . . . 108 LYS CA . 26318 1 47 . 1 . 1 14 14 LYS CB C 13 32.202 0.000 . 1 . . . . . 108 LYS CB . 26318 1 48 . 1 . 1 14 14 LYS N N 15 125.296 0.034 . 1 . . . . . 108 LYS N . 26318 1 49 . 1 . 1 15 15 SER H H 1 8.486 0.004 . 1 . . . . . 109 SER H . 26318 1 50 . 1 . 1 15 15 SER CA C 13 59.8 0.076 . 1 . . . . . 109 SER CA . 26318 1 51 . 1 . 1 15 15 SER CB C 13 63.692 0.017 . 1 . . . . . 109 SER CB . 26318 1 52 . 1 . 1 15 15 SER N N 15 113.88 0.033 . 1 . . . . . 109 SER N . 26318 1 53 . 1 . 1 16 16 ILE H H 1 7.518 0.004 . 1 . . . . . 110 ILE H . 26318 1 54 . 1 . 1 16 16 ILE CA C 13 61.757 0.080 . 1 . . . . . 110 ILE CA . 26318 1 55 . 1 . 1 16 16 ILE CB C 13 35.787 0.000 . 1 . . . . . 110 ILE CB . 26318 1 56 . 1 . 1 16 16 ILE N N 15 123.996 0.020 . 1 . . . . . 110 ILE N . 26318 1 57 . 1 . 1 17 17 ASP H H 1 7.656 0.004 . 1 . . . . . 111 ASP H . 26318 1 58 . 1 . 1 17 17 ASP CA C 13 51.581 0.056 . 1 . . . . . 111 ASP CA . 26318 1 59 . 1 . 1 17 17 ASP CB C 13 42.259 0.043 . 1 . . . . . 111 ASP CB . 26318 1 60 . 1 . 1 17 17 ASP N N 15 128.591 0.019 . 1 . . . . . 111 ASP N . 26318 1 61 . 1 . 1 18 18 ASN H H 1 8.347 0.003 . 1 . . . . . 112 ASN H . 26318 1 62 . 1 . 1 18 18 ASN CA C 13 57.176 0.051 . 1 . . . . . 112 ASN CA . 26318 1 63 . 1 . 1 18 18 ASN CB C 13 37.825 0.001 . 1 . . . . . 112 ASN CB . 26318 1 64 . 1 . 1 18 18 ASN N N 15 117.174 0.038 . 1 . . . . . 112 ASN N . 26318 1 65 . 1 . 1 19 19 LYS H H 1 7.776 0.002 . 1 . . . . . 113 LYS H . 26318 1 66 . 1 . 1 19 19 LYS CA C 13 59.257 0.050 . 1 . . . . . 113 LYS CA . 26318 1 67 . 1 . 1 19 19 LYS CB C 13 31.975 0.058 . 1 . . . . . 113 LYS CB . 26318 1 68 . 1 . 1 19 19 LYS N N 15 120.173 0.028 . 1 . . . . . 113 LYS N . 26318 1 69 . 1 . 1 20 20 ALA H H 1 8.136 0.003 . 1 . . . . . 114 ALA H . 26318 1 70 . 1 . 1 20 20 ALA CA C 13 55.01 0.074 . 1 . . . . . 114 ALA CA . 26318 1 71 . 1 . 1 20 20 ALA CB C 13 18.916 0.022 . 1 . . . . . 114 ALA CB . 26318 1 72 . 1 . 1 20 20 ALA N N 15 121.807 0.032 . 1 . . . . . 114 ALA N . 26318 1 73 . 1 . 1 21 21 LEU H H 1 8.554 0.005 . 1 . . . . . 115 LEU H . 26318 1 74 . 1 . 1 21 21 LEU CA C 13 58.471 0.075 . 1 . . . . . 115 LEU CA . 26318 1 75 . 1 . 1 21 21 LEU CB C 13 42.147 0.020 . 1 . . . . . 115 LEU CB . 26318 1 76 . 1 . 1 21 21 LEU N N 15 121.108 0.075 . 1 . . . . . 115 LEU N . 26318 1 77 . 1 . 1 22 22 TYR H H 1 8.35 0.006 . 1 . . . . . 116 TYR H . 26318 1 78 . 1 . 1 22 22 TYR CA C 13 62.312 0.146 . 1 . . . . . 116 TYR CA . 26318 1 79 . 1 . 1 22 22 TYR CB C 13 38.58 0.037 . 1 . . . . . 116 TYR CB . 26318 1 80 . 1 . 1 22 22 TYR N N 15 121.491 0.033 . 1 . . . . . 116 TYR N . 26318 1 81 . 1 . 1 23 23 ASP H H 1 9.052 0.008 . 1 . . . . . 117 ASP H . 26318 1 82 . 1 . 1 23 23 ASP CA C 13 57.675 0.065 . 1 . . . . . 117 ASP CA . 26318 1 83 . 1 . 1 23 23 ASP CB C 13 40.126 0.015 . 1 . . . . . 117 ASP CB . 26318 1 84 . 1 . 1 23 23 ASP N N 15 120.622 0.027 . 1 . . . . . 117 ASP N . 26318 1 85 . 1 . 1 24 24 THR H H 1 7.953 0.004 . 1 . . . . . 118 THR H . 26318 1 86 . 1 . 1 24 24 THR CA C 13 66.671 0.133 . 1 . . . . . 118 THR CA . 26318 1 87 . 1 . 1 24 24 THR CB C 13 69.139 0.143 . 1 . . . . . 118 THR CB . 26318 1 88 . 1 . 1 24 24 THR N N 15 115.533 0.030 . 1 . . . . . 118 THR N . 26318 1 89 . 1 . 1 25 25 PHE H H 1 8.126 0.007 . 1 . . . . . 119 PHE H . 26318 1 90 . 1 . 1 25 25 PHE CA C 13 61.642 0.088 . 1 . . . . . 119 PHE CA . 26318 1 91 . 1 . 1 25 25 PHE CB C 13 39.557 0.022 . 1 . . . . . 119 PHE CB . 26318 1 92 . 1 . 1 25 25 PHE N N 15 116.128 0.076 . 1 . . . . . 119 PHE N . 26318 1 93 . 1 . 1 26 26 SER H H 1 8.562 0.005 . 1 . . . . . 120 SER H . 26318 1 94 . 1 . 1 26 26 SER CA C 13 61.282 0.074 . 1 . . . . . 120 SER CA . 26318 1 95 . 1 . 1 26 26 SER CB C 13 62.372 0.071 . 1 . . . . . 120 SER CB . 26318 1 96 . 1 . 1 26 26 SER N N 15 118.098 0.028 . 1 . . . . . 120 SER N . 26318 1 97 . 1 . 1 27 27 ALA H H 1 7.037 0.003 . 1 . . . . . 121 ALA H . 26318 1 98 . 1 . 1 27 27 ALA CA C 13 53.673 0.070 . 1 . . . . . 121 ALA CA . 26318 1 99 . 1 . 1 27 27 ALA CB C 13 18.462 0.010 . 1 . . . . . 121 ALA CB . 26318 1 100 . 1 . 1 27 27 ALA N N 15 121.523 0.032 . 1 . . . . . 121 ALA N . 26318 1 101 . 1 . 1 28 28 PHE H H 1 7.407 0.004 . 1 . . . . . 122 PHE H . 26318 1 102 . 1 . 1 28 28 PHE CA C 13 59.157 0.063 . 1 . . . . . 122 PHE CA . 26318 1 103 . 1 . 1 28 28 PHE CB C 13 39.315 0.010 . 1 . . . . . 122 PHE CB . 26318 1 104 . 1 . 1 28 28 PHE N N 15 113.184 0.033 . 1 . . . . . 122 PHE N . 26318 1 105 . 1 . 1 29 29 GLY H H 1 7.321 0.004 . 1 . . . . . 123 GLY H . 26318 1 106 . 1 . 1 29 29 GLY CA C 13 44.655 0.067 . 1 . . . . . 123 GLY CA . 26318 1 107 . 1 . 1 29 29 GLY N N 15 104.363 0.028 . 1 . . . . . 123 GLY N . 26318 1 108 . 1 . 1 30 30 ASN H H 1 8.391 0.005 . 1 . . . . . 124 ASN H . 26318 1 109 . 1 . 1 30 30 ASN CA C 13 54.032 0.069 . 1 . . . . . 124 ASN CA . 26318 1 110 . 1 . 1 30 30 ASN CB C 13 38.614 0.029 . 1 . . . . . 124 ASN CB . 26318 1 111 . 1 . 1 30 30 ASN N N 15 115.752 0.045 . 1 . . . . . 124 ASN N . 26318 1 112 . 1 . 1 31 31 ILE H H 1 8.773 0.004 . 1 . . . . . 125 ILE H . 26318 1 113 . 1 . 1 31 31 ILE CA C 13 62.154 0.090 . 1 . . . . . 125 ILE CA . 26318 1 114 . 1 . 1 31 31 ILE N N 15 127.59 0.025 . 1 . . . . . 125 ILE N . 26318 1 115 . 1 . 1 32 32 LEU H H 1 9.052 0.007 . 1 . . . . . 126 LEU H . 26318 1 116 . 1 . 1 32 32 LEU CA C 13 56.333 0.117 . 1 . . . . . 126 LEU CA . 26318 1 117 . 1 . 1 32 32 LEU CB C 13 42.161 0.006 . 1 . . . . . 126 LEU CB . 26318 1 118 . 1 . 1 32 32 LEU N N 15 127.952 0.026 . 1 . . . . . 126 LEU N . 26318 1 119 . 1 . 1 33 33 SER H H 1 7.532 0.003 . 1 . . . . . 127 SER H . 26318 1 120 . 1 . 1 33 33 SER CA C 13 58.093 0.038 . 1 . . . . . 127 SER CA . 26318 1 121 . 1 . 1 33 33 SER CB C 13 64.735 0.004 . 1 . . . . . 127 SER CB . 26318 1 122 . 1 . 1 33 33 SER N N 15 110.63 0.044 . 1 . . . . . 127 SER N . 26318 1 123 . 1 . 1 34 34 CYS H H 1 8.503 0.004 . 1 . . . . . 128 CYS H . 26318 1 124 . 1 . 1 34 34 CYS CA C 13 57.325 0.006 . 1 . . . . . 128 CYS CA . 26318 1 125 . 1 . 1 34 34 CYS N N 15 119.3 0.021 . 1 . . . . . 128 CYS N . 26318 1 126 . 1 . 1 35 35 LYS H H 1 8.558 0.002 . 1 . . . . . 129 LYS H . 26318 1 127 . 1 . 1 35 35 LYS CA C 13 55.901 0.025 . 1 . . . . . 129 LYS CA . 26318 1 128 . 1 . 1 35 35 LYS CB C 13 36.396 0.000 . 1 . . . . . 129 LYS CB . 26318 1 129 . 1 . 1 35 35 LYS N N 15 121.296 0.009 . 1 . . . . . 129 LYS N . 26318 1 130 . 1 . 1 36 36 VAL H H 1 8.46 0.004 . 1 . . . . . 130 VAL H . 26318 1 131 . 1 . 1 36 36 VAL CA C 13 62.562 0.089 . 1 . . . . . 130 VAL CA . 26318 1 132 . 1 . 1 36 36 VAL N N 15 123.766 0.033 . 1 . . . . . 130 VAL N . 26318 1 133 . 1 . 1 37 37 VAL H H 1 8.666 0.002 . 1 . . . . . 131 VAL H . 26318 1 134 . 1 . 1 37 37 VAL CA C 13 63.836 0.052 . 1 . . . . . 131 VAL CA . 26318 1 135 . 1 . 1 37 37 VAL N N 15 129.289 0.007 . 1 . . . . . 131 VAL N . 26318 1 136 . 1 . 1 38 38 CYS H H 1 8.368 0.002 . 1 . . . . . 132 CYS H . 26318 1 137 . 1 . 1 38 38 CYS CA C 13 57.318 0.072 . 1 . . . . . 132 CYS CA . 26318 1 138 . 1 . 1 38 38 CYS CB C 13 31.575 0.000 . 1 . . . . . 132 CYS CB . 26318 1 139 . 1 . 1 38 38 CYS N N 15 123.875 0.039 . 1 . . . . . 132 CYS N . 26318 1 140 . 1 . 1 39 39 ASP H H 1 8.72 0.006 . 1 . . . . . 133 ASP H . 26318 1 141 . 1 . 1 39 39 ASP CA C 13 53.012 0.090 . 1 . . . . . 133 ASP CA . 26318 1 142 . 1 . 1 39 39 ASP CB C 13 41.996 0.030 . 1 . . . . . 133 ASP CB . 26318 1 143 . 1 . 1 39 39 ASP N N 15 123.303 0.036 . 1 . . . . . 133 ASP N . 26318 1 144 . 1 . 1 40 40 GLU H H 1 9.389 0.004 . 1 . . . . . 134 GLU H . 26318 1 145 . 1 . 1 40 40 GLU CA C 13 59.172 0.082 . 1 . . . . . 134 GLU CA . 26318 1 146 . 1 . 1 40 40 GLU CB C 13 28.738 0.000 . 1 . . . . . 134 GLU CB . 26318 1 147 . 1 . 1 40 40 GLU N N 15 119.955 0.035 . 1 . . . . . 134 GLU N . 26318 1 148 . 1 . 1 41 41 ASN H H 1 8.599 0.007 . 1 . . . . . 135 ASN H . 26318 1 149 . 1 . 1 41 41 ASN CA C 13 53.389 0.080 . 1 . . . . . 135 ASN CA . 26318 1 150 . 1 . 1 41 41 ASN CB C 13 39.471 0.026 . 1 . . . . . 135 ASN CB . 26318 1 151 . 1 . 1 41 41 ASN N N 15 116.986 0.020 . 1 . . . . . 135 ASN N . 26318 1 152 . 1 . 1 42 42 GLY H H 1 8.012 0.004 . 1 . . . . . 136 GLY H . 26318 1 153 . 1 . 1 42 42 GLY CA C 13 44.386 0.055 . 1 . . . . . 136 GLY CA . 26318 1 154 . 1 . 1 42 42 GLY N N 15 108.692 0.046 . 1 . . . . . 136 GLY N . 26318 1 155 . 1 . 1 43 43 SER H H 1 8.636 0.002 . 1 . . . . . 137 SER H . 26318 1 156 . 1 . 1 43 43 SER CA C 13 58.708 0.000 . 1 . . . . . 137 SER CA . 26318 1 157 . 1 . 1 43 43 SER N N 15 115.09 0.034 . 1 . . . . . 137 SER N . 26318 1 158 . 1 . 1 44 44 LYS H H 1 9.232 0.000 . 1 . . . . . 138 LYS H . 26318 1 159 . 1 . 1 44 44 LYS CA C 13 56.16 0.153 . 1 . . . . . 138 LYS CA . 26318 1 160 . 1 . 1 44 44 LYS N N 15 124.555 0.000 . 1 . . . . . 138 LYS N . 26318 1 161 . 1 . 1 45 45 GLY H H 1 9.229 0.006 . 1 . . . . . 139 GLY H . 26318 1 162 . 1 . 1 45 45 GLY CA C 13 45.834 0.060 . 1 . . . . . 139 GLY CA . 26318 1 163 . 1 . 1 45 45 GLY N N 15 107.852 0.023 . 1 . . . . . 139 GLY N . 26318 1 164 . 1 . 1 46 46 TYR H H 1 7.393 0.004 . 1 . . . . . 140 TYR H . 26318 1 165 . 1 . 1 46 46 TYR N N 15 114.545 0.088 . 1 . . . . . 140 TYR N . 26318 1 166 . 1 . 1 47 47 GLY H H 1 8.958 0.006 . 1 . . . . . 141 GLY H . 26318 1 167 . 1 . 1 47 47 GLY CA C 13 45.444 0.058 . 1 . . . . . 141 GLY CA . 26318 1 168 . 1 . 1 47 47 GLY N N 15 105.948 0.052 . 1 . . . . . 141 GLY N . 26318 1 169 . 1 . 1 48 48 PHE H H 1 8.724 0.009 . 1 . . . . . 142 PHE H . 26318 1 170 . 1 . 1 48 48 PHE CA C 13 56.128 0.128 . 1 . . . . . 142 PHE CA . 26318 1 171 . 1 . 1 48 48 PHE CB C 13 43.811 0.039 . 1 . . . . . 142 PHE CB . 26318 1 172 . 1 . 1 48 48 PHE N N 15 116.009 0.027 . 1 . . . . . 142 PHE N . 26318 1 173 . 1 . 1 49 49 VAL H H 1 8.257 0.006 . 1 . . . . . 143 VAL H . 26318 1 174 . 1 . 1 49 49 VAL CA C 13 61.921 0.121 . 1 . . . . . 143 VAL CA . 26318 1 175 . 1 . 1 49 49 VAL CB C 13 34.685 0.020 . 1 . . . . . 143 VAL CB . 26318 1 176 . 1 . 1 49 49 VAL N N 15 119.773 0.091 . 1 . . . . . 143 VAL N . 26318 1 177 . 1 . 1 50 50 HIS H H 1 8.809 0.003 . 1 . . . . . 144 HIS H . 26318 1 178 . 1 . 1 50 50 HIS CA C 13 53.343 0.098 . 1 . . . . . 144 HIS CA . 26318 1 179 . 1 . 1 50 50 HIS CB C 13 31.505 0.044 . 1 . . . . . 144 HIS CB . 26318 1 180 . 1 . 1 50 50 HIS N N 15 127.313 0.030 . 1 . . . . . 144 HIS N . 26318 1 181 . 1 . 1 51 51 PHE H H 1 8.934 0.004 . 1 . . . . . 145 PHE H . 26318 1 182 . 1 . 1 51 51 PHE CA C 13 58.845 0.112 . 1 . . . . . 145 PHE CA . 26318 1 183 . 1 . 1 51 51 PHE CB C 13 41.984 0.000 . 1 . . . . . 145 PHE CB . 26318 1 184 . 1 . 1 51 51 PHE N N 15 125.082 0.032 . 1 . . . . . 145 PHE N . 26318 1 185 . 1 . 1 52 52 GLU H H 1 8.522 0.005 . 1 . . . . . 146 GLU H . 26318 1 186 . 1 . 1 52 52 GLU CA C 13 59.384 0.046 . 1 . . . . . 146 GLU CA . 26318 1 187 . 1 . 1 52 52 GLU CB C 13 31.257 0.000 . 1 . . . . . 146 GLU CB . 26318 1 188 . 1 . 1 52 52 GLU N N 15 119.305 0.050 . 1 . . . . . 146 GLU N . 26318 1 189 . 1 . 1 53 53 THR H H 1 8.089 0.005 . 1 . . . . . 147 THR H . 26318 1 190 . 1 . 1 53 53 THR CA C 13 58.656 0.085 . 1 . . . . . 147 THR CA . 26318 1 191 . 1 . 1 53 53 THR CB C 13 72.13 0.005 . 1 . . . . . 147 THR CB . 26318 1 192 . 1 . 1 53 53 THR N N 15 104.52 0.031 . 1 . . . . . 147 THR N . 26318 1 193 . 1 . 1 54 54 GLN H H 1 8.843 0.006 . 1 . . . . . 148 GLN H . 26318 1 194 . 1 . 1 54 54 GLN CA C 13 58.605 0.110 . 1 . . . . . 148 GLN CA . 26318 1 195 . 1 . 1 54 54 GLN CB C 13 28.561 0.018 . 1 . . . . . 148 GLN CB . 26318 1 196 . 1 . 1 54 54 GLN N N 15 121.694 0.026 . 1 . . . . . 148 GLN N . 26318 1 197 . 1 . 1 55 55 GLU H H 1 8.838 0.004 . 1 . . . . . 149 GLU H . 26318 1 198 . 1 . 1 55 55 GLU CA C 13 60.107 0.042 . 1 . . . . . 149 GLU CA . 26318 1 199 . 1 . 1 55 55 GLU CB C 13 28.839 0.033 . 1 . . . . . 149 GLU CB . 26318 1 200 . 1 . 1 55 55 GLU N N 15 118.848 0.024 . 1 . . . . . 149 GLU N . 26318 1 201 . 1 . 1 56 56 ALA H H 1 7.424 0.005 . 1 . . . . . 150 ALA H . 26318 1 202 . 1 . 1 56 56 ALA CA C 13 55.059 0.052 . 1 . . . . . 150 ALA CA . 26318 1 203 . 1 . 1 56 56 ALA CB C 13 20.264 0.032 . 1 . . . . . 150 ALA CB . 26318 1 204 . 1 . 1 56 56 ALA N N 15 121.887 0.022 . 1 . . . . . 150 ALA N . 26318 1 205 . 1 . 1 57 57 ALA H H 1 6.558 0.004 . 1 . . . . . 151 ALA H . 26318 1 206 . 1 . 1 57 57 ALA CA C 13 55.124 0.040 . 1 . . . . . 151 ALA CA . 26318 1 207 . 1 . 1 57 57 ALA CB C 13 18.532 0.009 . 1 . . . . . 151 ALA CB . 26318 1 208 . 1 . 1 57 57 ALA N N 15 117.507 0.027 . 1 . . . . . 151 ALA N . 26318 1 209 . 1 . 1 58 58 GLU H H 1 8.011 0.006 . 1 . . . . . 152 GLU H . 26318 1 210 . 1 . 1 58 58 GLU CA C 13 59.317 0.056 . 1 . . . . . 152 GLU CA . 26318 1 211 . 1 . 1 58 58 GLU CB C 13 29.319 0.056 . 1 . . . . . 152 GLU CB . 26318 1 212 . 1 . 1 58 58 GLU N N 15 115.261 0.039 . 1 . . . . . 152 GLU N . 26318 1 213 . 1 . 1 59 59 ARG H H 1 7.879 0.004 . 1 . . . . . 153 ARG H . 26318 1 214 . 1 . 1 59 59 ARG CA C 13 59.146 0.091 . 1 . . . . . 153 ARG CA . 26318 1 215 . 1 . 1 59 59 ARG CB C 13 30.757 0.037 . 1 . . . . . 153 ARG CB . 26318 1 216 . 1 . 1 59 59 ARG N N 15 120.045 0.024 . 1 . . . . . 153 ARG N . 26318 1 217 . 1 . 1 60 60 ALA H H 1 7.885 0.004 . 1 . . . . . 154 ALA H . 26318 1 218 . 1 . 1 60 60 ALA CA C 13 54.616 0.096 . 1 . . . . . 154 ALA CA . 26318 1 219 . 1 . 1 60 60 ALA CB C 13 19.418 0.043 . 1 . . . . . 154 ALA CB . 26318 1 220 . 1 . 1 60 60 ALA N N 15 121.402 0.037 . 1 . . . . . 154 ALA N . 26318 1 221 . 1 . 1 61 61 ILE H H 1 7.877 0.004 . 1 . . . . . 155 ILE H . 26318 1 222 . 1 . 1 61 61 ILE CA C 13 65.914 0.099 . 1 . . . . . 155 ILE CA . 26318 1 223 . 1 . 1 61 61 ILE CB C 13 38.831 0.053 . 1 . . . . . 155 ILE CB . 26318 1 224 . 1 . 1 61 61 ILE N N 15 117.333 0.060 . 1 . . . . . 155 ILE N . 26318 1 225 . 1 . 1 62 62 GLU H H 1 7.749 0.003 . 1 . . . . . 156 GLU H . 26318 1 226 . 1 . 1 62 62 GLU CA C 13 59.313 0.056 . 1 . . . . . 156 GLU CA . 26318 1 227 . 1 . 1 62 62 GLU CB C 13 29.769 0.128 . 1 . . . . . 156 GLU CB . 26318 1 228 . 1 . 1 62 62 GLU N N 15 117.955 0.025 . 1 . . . . . 156 GLU N . 26318 1 229 . 1 . 1 63 63 LYS H H 1 7.95 0.002 . 1 . . . . . 157 LYS H . 26318 1 230 . 1 . 1 63 63 LYS CA C 13 56.703 0.073 . 1 . . . . . 157 LYS CA . 26318 1 231 . 1 . 1 63 63 LYS CB C 13 33.243 0.045 . 1 . . . . . 157 LYS CB . 26318 1 232 . 1 . 1 63 63 LYS N N 15 114.289 0.041 . 1 . . . . . 157 LYS N . 26318 1 233 . 1 . 1 64 64 MET H H 1 7.931 0.006 . 1 . . . . . 158 MET H . 26318 1 234 . 1 . 1 64 64 MET CA C 13 53.887 0.104 . 1 . . . . . 158 MET CA . 26318 1 235 . 1 . 1 64 64 MET CB C 13 32.593 0.000 . 1 . . . . . 158 MET CB . 26318 1 236 . 1 . 1 64 64 MET N N 15 112.243 0.044 . 1 . . . . . 158 MET N . 26318 1 237 . 1 . 1 65 65 ASN H H 1 8.002 0.005 . 1 . . . . . 159 ASN H . 26318 1 238 . 1 . 1 65 65 ASN CA C 13 56.823 0.102 . 1 . . . . . 159 ASN CA . 26318 1 239 . 1 . 1 65 65 ASN CB C 13 38.49 0.003 . 1 . . . . . 159 ASN CB . 26318 1 240 . 1 . 1 65 65 ASN N N 15 116.356 0.018 . 1 . . . . . 159 ASN N . 26318 1 241 . 1 . 1 66 66 GLY H H 1 8.923 0.005 . 1 . . . . . 160 GLY H . 26318 1 242 . 1 . 1 66 66 GLY CA C 13 46.061 0.078 . 1 . . . . . 160 GLY CA . 26318 1 243 . 1 . 1 66 66 GLY N N 15 117.242 0.027 . 1 . . . . . 160 GLY N . 26318 1 244 . 1 . 1 67 67 MET H H 1 7.805 0.003 . 1 . . . . . 161 MET H . 26318 1 245 . 1 . 1 67 67 MET CA C 13 54.165 0.084 . 1 . . . . . 161 MET CA . 26318 1 246 . 1 . 1 67 67 MET CB C 13 33.108 0.091 . 1 . . . . . 161 MET CB . 26318 1 247 . 1 . 1 67 67 MET N N 15 119.983 0.027 . 1 . . . . . 161 MET N . 26318 1 248 . 1 . 1 68 68 LEU H H 1 8.039 0.004 . 1 . . . . . 162 LEU H . 26318 1 249 . 1 . 1 68 68 LEU CA C 13 54.716 0.059 . 1 . . . . . 162 LEU CA . 26318 1 250 . 1 . 1 68 68 LEU CB C 13 42.817 0.022 . 1 . . . . . 162 LEU CB . 26318 1 251 . 1 . 1 68 68 LEU N N 15 120.388 0.022 . 1 . . . . . 162 LEU N . 26318 1 252 . 1 . 1 69 69 LEU H H 1 8.771 0.005 . 1 . . . . . 163 LEU H . 26318 1 253 . 1 . 1 69 69 LEU CA C 13 54.353 0.033 . 1 . . . . . 163 LEU CA . 26318 1 254 . 1 . 1 69 69 LEU CB C 13 43.879 0.009 . 1 . . . . . 163 LEU CB . 26318 1 255 . 1 . 1 69 69 LEU N N 15 126.336 0.028 . 1 . . . . . 163 LEU N . 26318 1 256 . 1 . 1 70 70 ASN H H 1 9.428 0.007 . 1 . . . . . 164 ASN H . 26318 1 257 . 1 . 1 70 70 ASN CA C 13 55.065 0.101 . 1 . . . . . 164 ASN CA . 26318 1 258 . 1 . 1 70 70 ASN CB C 13 36.337 0.015 . 1 . . . . . 164 ASN CB . 26318 1 259 . 1 . 1 70 70 ASN N N 15 126.947 0.034 . 1 . . . . . 164 ASN N . 26318 1 260 . 1 . 1 71 71 ASP H H 1 8.55 0.003 . 1 . . . . . 165 ASP H . 26318 1 261 . 1 . 1 71 71 ASP CA C 13 56.285 0.088 . 1 . . . . . 165 ASP CA . 26318 1 262 . 1 . 1 71 71 ASP CB C 13 40.265 0.082 . 1 . . . . . 165 ASP CB . 26318 1 263 . 1 . 1 71 71 ASP N N 15 110.392 0.038 . 1 . . . . . 165 ASP N . 26318 1 264 . 1 . 1 72 72 ARG H H 1 7.591 0.003 . 1 . . . . . 166 ARG H . 26318 1 265 . 1 . 1 72 72 ARG CA C 13 54.85 0.069 . 1 . . . . . 166 ARG CA . 26318 1 266 . 1 . 1 72 72 ARG CB C 13 33.177 0.009 . 1 . . . . . 166 ARG CB . 26318 1 267 . 1 . 1 72 72 ARG N N 15 119.019 0.022 . 1 . . . . . 166 ARG N . 26318 1 268 . 1 . 1 73 73 LYS H H 1 8.609 0.005 . 1 . . . . . 167 LYS H . 26318 1 269 . 1 . 1 73 73 LYS CA C 13 56.636 0.053 . 1 . . . . . 167 LYS CA . 26318 1 270 . 1 . 1 73 73 LYS CB C 13 32.861 0.055 . 1 . . . . . 167 LYS CB . 26318 1 271 . 1 . 1 73 73 LYS N N 15 125.077 0.050 . 1 . . . . . 167 LYS N . 26318 1 272 . 1 . 1 74 74 VAL H H 1 8.627 0.004 . 1 . . . . . 168 VAL H . 26318 1 273 . 1 . 1 74 74 VAL CA C 13 60.716 0.104 . 1 . . . . . 168 VAL CA . 26318 1 274 . 1 . 1 74 74 VAL N N 15 122.796 0.079 . 1 . . . . . 168 VAL N . 26318 1 275 . 1 . 1 75 75 PHE H H 1 7.994 0.006 . 1 . . . . . 169 PHE H . 26318 1 276 . 1 . 1 75 75 PHE CA C 13 55.892 0.117 . 1 . . . . . 169 PHE CA . 26318 1 277 . 1 . 1 75 75 PHE CB C 13 41.306 0.008 . 1 . . . . . 169 PHE CB . 26318 1 278 . 1 . 1 75 75 PHE N N 15 122.866 0.009 . 1 . . . . . 169 PHE N . 26318 1 279 . 1 . 1 76 76 VAL H H 1 8.265 0.003 . 1 . . . . . 170 VAL H . 26318 1 280 . 1 . 1 76 76 VAL CA C 13 60.212 0.087 . 1 . . . . . 170 VAL CA . 26318 1 281 . 1 . 1 76 76 VAL N N 15 126.009 0.065 . 1 . . . . . 170 VAL N . 26318 1 282 . 1 . 1 77 77 GLY H H 1 7.904 0.004 . 1 . . . . . 171 GLY H . 26318 1 283 . 1 . 1 77 77 GLY CA C 13 44.872 0.108 . 1 . . . . . 171 GLY CA . 26318 1 284 . 1 . 1 77 77 GLY N N 15 111.293 0.010 . 1 . . . . . 171 GLY N . 26318 1 285 . 1 . 1 78 78 ARG H H 1 8.534 0.003 . 1 . . . . . 172 ARG H . 26318 1 286 . 1 . 1 78 78 ARG CA C 13 55.876 0.114 . 1 . . . . . 172 ARG CA . 26318 1 287 . 1 . 1 78 78 ARG N N 15 118.79 0.081 . 1 . . . . . 172 ARG N . 26318 1 288 . 1 . 1 79 79 PHE H H 1 8.499 0.003 . 1 . . . . . 173 PHE H . 26318 1 289 . 1 . 1 79 79 PHE CA C 13 57.675 0.000 . 1 . . . . . 173 PHE CA . 26318 1 290 . 1 . 1 79 79 PHE N N 15 122.454 0.021 . 1 . . . . . 173 PHE N . 26318 1 291 . 1 . 1 82 82 ARG H H 1 8.149 0.000 . 1 . . . . . 176 ARG H . 26318 1 292 . 1 . 1 82 82 ARG N N 15 118.989 0.000 . 1 . . . . . 176 ARG N . 26318 1 293 . 1 . 1 83 83 LYS CA C 13 57.613 0.026 . 1 . . . . . 177 LYS CA . 26318 1 294 . 1 . 1 83 83 LYS CB C 13 30.07 0.000 . 1 . . . . . 177 LYS CB . 26318 1 295 . 1 . 1 84 84 GLU H H 1 8.019 0.004 . 1 . . . . . 178 GLU H . 26318 1 296 . 1 . 1 84 84 GLU CA C 13 58.163 0.059 . 1 . . . . . 178 GLU CA . 26318 1 297 . 1 . 1 84 84 GLU CB C 13 30.193 0.062 . 1 . . . . . 178 GLU CB . 26318 1 298 . 1 . 1 84 84 GLU N N 15 120.79 0.087 . 1 . . . . . 178 GLU N . 26318 1 299 . 1 . 1 85 85 ARG H H 1 8.129 0.006 . 1 . . . . . 179 ARG H . 26318 1 300 . 1 . 1 85 85 ARG CA C 13 57.844 0.034 . 1 . . . . . 179 ARG CA . 26318 1 301 . 1 . 1 85 85 ARG N N 15 120.414 0.056 . 1 . . . . . 179 ARG N . 26318 1 302 . 1 . 1 86 86 GLU H H 1 8.352 0.003 . 1 . . . . . 180 GLU H . 26318 1 303 . 1 . 1 86 86 GLU CA C 13 58.253 0.057 . 1 . . . . . 180 GLU CA . 26318 1 304 . 1 . 1 86 86 GLU CB C 13 29.784 0.007 . 1 . . . . . 180 GLU CB . 26318 1 305 . 1 . 1 86 86 GLU N N 15 119.953 0.036 . 1 . . . . . 180 GLU N . 26318 1 306 . 1 . 1 87 87 ALA H H 1 7.976 0.004 . 1 . . . . . 181 ALA H . 26318 1 307 . 1 . 1 87 87 ALA CA C 13 53.807 0.019 . 1 . . . . . 181 ALA CA . 26318 1 308 . 1 . 1 87 87 ALA CB C 13 18.717 0.018 . 1 . . . . . 181 ALA CB . 26318 1 309 . 1 . 1 87 87 ALA N N 15 122.825 0.035 . 1 . . . . . 181 ALA N . 26318 1 310 . 1 . 1 88 88 GLU H H 1 7.882 0.003 . 1 . . . . . 182 GLU H . 26318 1 311 . 1 . 1 88 88 GLU CA C 13 57.692 0.003 . 1 . . . . . 182 GLU CA . 26318 1 312 . 1 . 1 88 88 GLU N N 15 118.409 0.094 . 1 . . . . . 182 GLU N . 26318 1 313 . 1 . 1 89 89 LEU H H 1 8.022 0.001 . 1 . . . . . 183 LEU H . 26318 1 314 . 1 . 1 89 89 LEU CA C 13 56.093 0.029 . 1 . . . . . 183 LEU CA . 26318 1 315 . 1 . 1 89 89 LEU CB C 13 42.262 0.037 . 1 . . . . . 183 LEU CB . 26318 1 316 . 1 . 1 89 89 LEU N N 15 120.44 0.020 . 1 . . . . . 183 LEU N . 26318 1 317 . 1 . 1 90 90 GLY H H 1 8.176 0.003 . 1 . . . . . 184 GLY H . 26318 1 318 . 1 . 1 90 90 GLY CA C 13 45.759 0.022 . 1 . . . . . 184 GLY CA . 26318 1 319 . 1 . 1 90 90 GLY N N 15 108.299 0.021 . 1 . . . . . 184 GLY N . 26318 1 320 . 1 . 1 91 91 ALA H H 1 8.026 0.009 . 1 . . . . . 185 ALA H . 26318 1 321 . 1 . 1 91 91 ALA CA C 13 53.269 0.073 . 1 . . . . . 185 ALA CA . 26318 1 322 . 1 . 1 91 91 ALA CB C 13 19.124 0.007 . 1 . . . . . 185 ALA CB . 26318 1 323 . 1 . 1 91 91 ALA N N 15 123.685 0.023 . 1 . . . . . 185 ALA N . 26318 1 324 . 1 . 1 92 92 ARG H H 1 8.145 0.004 . 1 . . . . . 186 ARG H . 26318 1 325 . 1 . 1 92 92 ARG CA C 13 56.613 0.073 . 1 . . . . . 186 ARG CA . 26318 1 326 . 1 . 1 92 92 ARG CB C 13 30.579 0.057 . 1 . . . . . 186 ARG CB . 26318 1 327 . 1 . 1 92 92 ARG N N 15 118.899 0.014 . 1 . . . . . 186 ARG N . 26318 1 328 . 1 . 1 93 93 ALA H H 1 8.089 0.003 . 1 . . . . . 187 ALA H . 26318 1 329 . 1 . 1 93 93 ALA CA C 13 53.212 0.053 . 1 . . . . . 187 ALA CA . 26318 1 330 . 1 . 1 93 93 ALA CB C 13 19.138 0.018 . 1 . . . . . 187 ALA CB . 26318 1 331 . 1 . 1 93 93 ALA N N 15 123.842 0.042 . 1 . . . . . 187 ALA N . 26318 1 332 . 1 . 1 94 94 LYS H H 1 8.103 0.003 . 1 . . . . . 188 LYS H . 26318 1 333 . 1 . 1 94 94 LYS CA C 13 56.958 0.067 . 1 . . . . . 188 LYS CA . 26318 1 334 . 1 . 1 94 94 LYS CB C 13 32.951 0.000 . 1 . . . . . 188 LYS CB . 26318 1 335 . 1 . 1 94 94 LYS N N 15 119.001 0.027 . 1 . . . . . 188 LYS N . 26318 1 336 . 1 . 1 95 95 GLU H H 1 8.162 0.003 . 1 . . . . . 189 GLU H . 26318 1 337 . 1 . 1 95 95 GLU CA C 13 56.082 0.066 . 1 . . . . . 189 GLU CA . 26318 1 338 . 1 . 1 95 95 GLU CB C 13 30.024 0.009 . 1 . . . . . 189 GLU CB . 26318 1 339 . 1 . 1 95 95 GLU N N 15 123.268 0.000 . 1 . . . . . 189 GLU N . 26318 1 340 . 1 . 1 96 96 PHE H H 1 7.817 0.004 . 1 . . . . . 190 PHE H . 26318 1 341 . 1 . 1 96 96 PHE CA C 13 57.705 0.000 . 1 . . . . . 190 PHE CA . 26318 1 342 . 1 . 1 96 96 PHE N N 15 118.304 0.028 . 1 . . . . . 190 PHE N . 26318 1 343 . 1 . 1 97 97 THR H H 1 8.502 0.002 . 1 . . . . . 191 THR H . 26318 1 344 . 1 . 1 97 97 THR CA C 13 63.852 0.035 . 1 . . . . . 191 THR CA . 26318 1 345 . 1 . 1 97 97 THR N N 15 113.935 0.072 . 1 . . . . . 191 THR N . 26318 1 346 . 1 . 1 98 98 ASN H H 1 8.382 0.014 . 1 . . . . . 192 ASN H . 26318 1 347 . 1 . 1 98 98 ASN CA C 13 52.93 0.064 . 1 . . . . . 192 ASN CA . 26318 1 348 . 1 . 1 98 98 ASN CB C 13 39.808 0.034 . 1 . . . . . 192 ASN CB . 26318 1 349 . 1 . 1 98 98 ASN N N 15 123.302 0.027 . 1 . . . . . 192 ASN N . 26318 1 350 . 1 . 1 99 99 VAL H H 1 9.362 0.009 . 1 . . . . . 193 VAL H . 26318 1 351 . 1 . 1 99 99 VAL CA C 13 61.022 0.081 . 1 . . . . . 193 VAL CA . 26318 1 352 . 1 . 1 99 99 VAL N N 15 122.577 0.016 . 1 . . . . . 193 VAL N . 26318 1 353 . 1 . 1 100 100 TYR H H 1 9.109 0.001 . 1 . . . . . 194 TYR H . 26318 1 354 . 1 . 1 100 100 TYR CA C 13 55.58 0.000 . 1 . . . . . 194 TYR CA . 26318 1 355 . 1 . 1 100 100 TYR N N 15 126.238 0.030 . 1 . . . . . 194 TYR N . 26318 1 356 . 1 . 1 101 101 ILE CA C 13 59.18 0.000 . 1 . . . . . 195 ILE CA . 26318 1 357 . 1 . 1 102 102 LYS H H 1 9.221 0.002 . 1 . . . . . 196 LYS H . 26318 1 358 . 1 . 1 102 102 LYS CA C 13 54.963 0.044 . 1 . . . . . 196 LYS CA . 26318 1 359 . 1 . 1 102 102 LYS N N 15 122.643 0.000 . 1 . . . . . 196 LYS N . 26318 1 360 . 1 . 1 103 103 ASN H H 1 8.057 0.005 . 1 . . . . . 197 ASN H . 26318 1 361 . 1 . 1 103 103 ASN CA C 13 54.532 0.161 . 1 . . . . . 197 ASN CA . 26318 1 362 . 1 . 1 103 103 ASN CB C 13 37.698 0.000 . 1 . . . . . 197 ASN CB . 26318 1 363 . 1 . 1 103 103 ASN N N 15 114.467 0.068 . 1 . . . . . 197 ASN N . 26318 1 364 . 1 . 1 104 104 PHE H H 1 6.902 0.006 . 1 . . . . . 198 PHE H . 26318 1 365 . 1 . 1 104 104 PHE CA C 13 54.805 0.040 . 1 . . . . . 198 PHE CA . 26318 1 366 . 1 . 1 104 104 PHE CB C 13 39.715 0.000 . 1 . . . . . 198 PHE CB . 26318 1 367 . 1 . 1 104 104 PHE N N 15 109.809 0.052 . 1 . . . . . 198 PHE N . 26318 1 368 . 1 . 1 105 105 GLY H H 1 8.506 0.006 . 1 . . . . . 199 GLY H . 26318 1 369 . 1 . 1 105 105 GLY CA C 13 45.405 0.148 . 1 . . . . . 199 GLY CA . 26318 1 370 . 1 . 1 105 105 GLY N N 15 108.972 0.042 . 1 . . . . . 199 GLY N . 26318 1 371 . 1 . 1 106 106 GLU H H 1 8.696 0.003 . 1 . . . . . 200 GLU H . 26318 1 372 . 1 . 1 106 106 GLU CA C 13 58.114 0.109 . 1 . . . . . 200 GLU CA . 26318 1 373 . 1 . 1 106 106 GLU CB C 13 30.387 0.000 . 1 . . . . . 200 GLU CB . 26318 1 374 . 1 . 1 106 106 GLU N N 15 118.987 0.028 . 1 . . . . . 200 GLU N . 26318 1 375 . 1 . 1 107 107 ASP H H 1 8.618 0.006 . 1 . . . . . 201 ASP H . 26318 1 376 . 1 . 1 107 107 ASP CA C 13 53.415 0.065 . 1 . . . . . 201 ASP CA . 26318 1 377 . 1 . 1 107 107 ASP CB C 13 39.7 0.008 . 1 . . . . . 201 ASP CB . 26318 1 378 . 1 . 1 107 107 ASP N N 15 118.934 0.031 . 1 . . . . . 201 ASP N . 26318 1 379 . 1 . 1 108 108 MET H H 1 7.468 0.003 . 1 . . . . . 202 MET H . 26318 1 380 . 1 . 1 108 108 MET CA C 13 54.704 0.043 . 1 . . . . . 202 MET CA . 26318 1 381 . 1 . 1 108 108 MET CB C 13 32.611 0.004 . 1 . . . . . 202 MET CB . 26318 1 382 . 1 . 1 108 108 MET N N 15 120.029 0.041 . 1 . . . . . 202 MET N . 26318 1 383 . 1 . 1 109 109 ASP H H 1 7.029 0.002 . 1 . . . . . 203 ASP H . 26318 1 384 . 1 . 1 109 109 ASP CA C 13 52.237 0.091 . 1 . . . . . 203 ASP CA . 26318 1 385 . 1 . 1 109 109 ASP N N 15 122.022 0.018 . 1 . . . . . 203 ASP N . 26318 1 386 . 1 . 1 110 110 ASP H H 1 8.374 0.005 . 1 . . . . . 204 ASP H . 26318 1 387 . 1 . 1 110 110 ASP CA C 13 58.374 0.059 . 1 . . . . . 204 ASP CA . 26318 1 388 . 1 . 1 110 110 ASP CB C 13 40.374 0.000 . 1 . . . . . 204 ASP CB . 26318 1 389 . 1 . 1 110 110 ASP N N 15 119.11 0.086 . 1 . . . . . 204 ASP N . 26318 1 390 . 1 . 1 111 111 GLU H H 1 7.991 0.006 . 1 . . . . . 205 GLU H . 26318 1 391 . 1 . 1 111 111 GLU CA C 13 59.69 0.082 . 1 . . . . . 205 GLU CA . 26318 1 392 . 1 . 1 111 111 GLU CB C 13 29.152 0.035 . 1 . . . . . 205 GLU CB . 26318 1 393 . 1 . 1 111 111 GLU N N 15 118.973 0.016 . 1 . . . . . 205 GLU N . 26318 1 394 . 1 . 1 112 112 ARG H H 1 8.392 0.151 . 1 . . . . . 206 ARG H . 26318 1 395 . 1 . 1 112 112 ARG CA C 13 59.466 0.224 . 1 . . . . . 206 ARG CA . 26318 1 396 . 1 . 1 112 112 ARG CB C 13 30.939 0.000 . 1 . . . . . 206 ARG CB . 26318 1 397 . 1 . 1 112 112 ARG N N 15 120.529 0.559 . 1 . . . . . 206 ARG N . 26318 1 398 . 1 . 1 114 114 LYS H H 1 8.2 0.003 . 1 . . . . . 208 LYS H . 26318 1 399 . 1 . 1 114 114 LYS CA C 13 59.916 0.071 . 1 . . . . . 208 LYS CA . 26318 1 400 . 1 . 1 114 114 LYS CB C 13 32.234 0.000 . 1 . . . . . 208 LYS CB . 26318 1 401 . 1 . 1 114 114 LYS N N 15 119.666 0.010 . 1 . . . . . 208 LYS N . 26318 1 402 . 1 . 1 115 115 ASP H H 1 8.021 0.126 . 1 . . . . . 209 ASP H . 26318 1 403 . 1 . 1 115 115 ASP CA C 13 57.292 0.100 . 1 . . . . . 209 ASP CA . 26318 1 404 . 1 . 1 115 115 ASP CB C 13 40.947 0.343 . 1 . . . . . 209 ASP CB . 26318 1 405 . 1 . 1 115 115 ASP N N 15 119.818 0.518 . 1 . . . . . 209 ASP N . 26318 1 406 . 1 . 1 116 116 LEU H H 1 7.917 0.005 . 1 . . . . . 210 LEU H . 26318 1 407 . 1 . 1 116 116 LEU CA C 13 57.5 0.024 . 1 . . . . . 210 LEU CA . 26318 1 408 . 1 . 1 116 116 LEU CB C 13 43.37 0.038 . 1 . . . . . 210 LEU CB . 26318 1 409 . 1 . 1 116 116 LEU N N 15 119.281 0.015 . 1 . . . . . 210 LEU N . 26318 1 410 . 1 . 1 117 117 PHE H H 1 8.046 0.004 . 1 . . . . . 211 PHE H . 26318 1 411 . 1 . 1 117 117 PHE CA C 13 60.371 0.107 . 1 . . . . . 211 PHE CA . 26318 1 412 . 1 . 1 117 117 PHE CB C 13 39.876 0.013 . 1 . . . . . 211 PHE CB . 26318 1 413 . 1 . 1 117 117 PHE N N 15 112.64 0.053 . 1 . . . . . 211 PHE N . 26318 1 414 . 1 . 1 118 118 GLY H H 1 8.564 0.006 . 1 . . . . . 212 GLY H . 26318 1 415 . 1 . 1 118 118 GLY CA C 13 46.949 0.125 . 1 . . . . . 212 GLY CA . 26318 1 416 . 1 . 1 118 118 GLY N N 15 110.608 0.037 . 1 . . . . . 212 GLY N . 26318 1 417 . 1 . 1 119 119 LYS H H 1 7.336 0.004 . 1 . . . . . 213 LYS H . 26318 1 418 . 1 . 1 119 119 LYS CA C 13 57.331 0.094 . 1 . . . . . 213 LYS CA . 26318 1 419 . 1 . 1 119 119 LYS CB C 13 31.284 0.044 . 1 . . . . . 213 LYS CB . 26318 1 420 . 1 . 1 119 119 LYS N N 15 116.209 0.020 . 1 . . . . . 213 LYS N . 26318 1 421 . 1 . 1 120 120 PHE H H 1 7.473 0.004 . 1 . . . . . 214 PHE H . 26318 1 422 . 1 . 1 120 120 PHE CA C 13 60.367 0.088 . 1 . . . . . 214 PHE CA . 26318 1 423 . 1 . 1 120 120 PHE CB C 13 39.106 0.000 . 1 . . . . . 214 PHE CB . 26318 1 424 . 1 . 1 120 120 PHE N N 15 117.245 0.029 . 1 . . . . . 214 PHE N . 26318 1 425 . 1 . 1 121 121 GLY H H 1 7.257 0.005 . 1 . . . . . 215 GLY H . 26318 1 426 . 1 . 1 121 121 GLY CA C 13 44.613 0.065 . 1 . . . . . 215 GLY CA . 26318 1 427 . 1 . 1 121 121 GLY N N 15 104.914 0.038 . 1 . . . . . 215 GLY N . 26318 1 428 . 1 . 1 123 123 ALA H H 1 8.655 0.004 . 1 . . . . . 217 ALA H . 26318 1 429 . 1 . 1 123 123 ALA CA C 13 50.911 0.000 . 1 . . . . . 217 ALA CA . 26318 1 430 . 1 . 1 123 123 ALA CB C 13 19.607 0.157 . 1 . . . . . 217 ALA CB . 26318 1 431 . 1 . 1 123 123 ALA N N 15 126.202 0.099 . 1 . . . . . 217 ALA N . 26318 1 432 . 1 . 1 124 124 LEU H H 1 8.863 0.004 . 1 . . . . . 218 LEU H . 26318 1 433 . 1 . 1 124 124 LEU CA C 13 56.096 0.012 . 1 . . . . . 218 LEU CA . 26318 1 434 . 1 . 1 124 124 LEU N N 15 123.257 0.013 . 1 . . . . . 218 LEU N . 26318 1 435 . 1 . 1 125 125 SER H H 1 7.241 0.001 . 1 . . . . . 219 SER H . 26318 1 436 . 1 . 1 125 125 SER CA C 13 57.787 0.027 . 1 . . . . . 219 SER CA . 26318 1 437 . 1 . 1 125 125 SER N N 15 109.79 0.036 . 1 . . . . . 219 SER N . 26318 1 438 . 1 . 1 126 126 VAL H H 1 8.05 0.004 . 1 . . . . . 220 VAL H . 26318 1 439 . 1 . 1 126 126 VAL CA C 13 61.587 0.032 . 1 . . . . . 220 VAL CA . 26318 1 440 . 1 . 1 126 126 VAL N N 15 122.704 0.012 . 1 . . . . . 220 VAL N . 26318 1 441 . 1 . 1 127 127 LYS H H 1 8.558 0.006 . 1 . . . . . 221 LYS H . 26318 1 442 . 1 . 1 127 127 LYS CA C 13 55.189 0.065 . 1 . . . . . 221 LYS CA . 26318 1 443 . 1 . 1 127 127 LYS CB C 13 36.543 0.032 . 1 . . . . . 221 LYS CB . 26318 1 444 . 1 . 1 127 127 LYS N N 15 124.513 0.059 . 1 . . . . . 221 LYS N . 26318 1 445 . 1 . 1 128 128 VAL H H 1 8.994 0.002 . 1 . . . . . 222 VAL H . 26318 1 446 . 1 . 1 128 128 VAL CA C 13 62.966 0.087 . 1 . . . . . 222 VAL CA . 26318 1 447 . 1 . 1 128 128 VAL N N 15 126.497 0.021 . 1 . . . . . 222 VAL N . 26318 1 448 . 1 . 1 129 129 MET H H 1 8.651 0.005 . 1 . . . . . 223 MET H . 26318 1 449 . 1 . 1 129 129 MET CA C 13 55.147 0.018 . 1 . . . . . 223 MET CA . 26318 1 450 . 1 . 1 129 129 MET CB C 13 30.785 0.000 . 1 . . . . . 223 MET CB . 26318 1 451 . 1 . 1 129 129 MET N N 15 127.15 0.055 . 1 . . . . . 223 MET N . 26318 1 452 . 1 . 1 130 130 THR H H 1 8.21 0.005 . 1 . . . . . 224 THR H . 26318 1 453 . 1 . 1 130 130 THR CA C 13 59.599 0.119 . 1 . . . . . 224 THR CA . 26318 1 454 . 1 . 1 130 130 THR CB C 13 72.568 0.124 . 1 . . . . . 224 THR CB . 26318 1 455 . 1 . 1 130 130 THR N N 15 113.459 0.035 . 1 . . . . . 224 THR N . 26318 1 456 . 1 . 1 131 131 ASP H H 1 8.644 0.006 . 1 . . . . . 225 ASP H . 26318 1 457 . 1 . 1 131 131 ASP CA C 13 52.41 0.110 . 1 . . . . . 225 ASP CA . 26318 1 458 . 1 . 1 131 131 ASP CB C 13 41.393 0.000 . 1 . . . . . 225 ASP CB . 26318 1 459 . 1 . 1 131 131 ASP N N 15 120.588 0.042 . 1 . . . . . 225 ASP N . 26318 1 460 . 1 . 1 132 132 GLU H H 1 9.148 0.003 . 1 . . . . . 226 GLU H . 26318 1 461 . 1 . 1 132 132 GLU CA C 13 59.457 0.056 . 1 . . . . . 226 GLU CA . 26318 1 462 . 1 . 1 132 132 GLU N N 15 118.673 0.024 . 1 . . . . . 226 GLU N . 26318 1 463 . 1 . 1 133 133 SER H H 1 8.436 0.005 . 1 . . . . . 227 SER H . 26318 1 464 . 1 . 1 133 133 SER CA C 13 58.624 0.043 . 1 . . . . . 227 SER CA . 26318 1 465 . 1 . 1 133 133 SER CB C 13 64.365 0.026 . 1 . . . . . 227 SER CB . 26318 1 466 . 1 . 1 133 133 SER N N 15 115.67 0.022 . 1 . . . . . 227 SER N . 26318 1 467 . 1 . 1 134 134 GLY H H 1 8.158 0.005 . 1 . . . . . 228 GLY H . 26318 1 468 . 1 . 1 134 134 GLY CA C 13 45.2 0.038 . 1 . . . . . 228 GLY CA . 26318 1 469 . 1 . 1 134 134 GLY N N 15 109.968 0.030 . 1 . . . . . 228 GLY N . 26318 1 470 . 1 . 1 135 135 LYS H H 1 8.067 0.004 . 1 . . . . . 229 LYS H . 26318 1 471 . 1 . 1 135 135 LYS CA C 13 55.614 0.086 . 1 . . . . . 229 LYS CA . 26318 1 472 . 1 . 1 135 135 LYS CB C 13 32.832 0.001 . 1 . . . . . 229 LYS CB . 26318 1 473 . 1 . 1 135 135 LYS N N 15 122.077 0.028 . 1 . . . . . 229 LYS N . 26318 1 474 . 1 . 1 136 136 SER H H 1 8.734 0.003 . 1 . . . . . 230 SER H . 26318 1 475 . 1 . 1 136 136 SER CA C 13 58.504 0.112 . 1 . . . . . 230 SER CA . 26318 1 476 . 1 . 1 136 136 SER N N 15 117.607 0.021 . 1 . . . . . 230 SER N . 26318 1 477 . 1 . 1 137 137 LYS H H 1 8.944 0.002 . 1 . . . . . 231 LYS H . 26318 1 478 . 1 . 1 137 137 LYS CA C 13 56.448 0.078 . 1 . . . . . 231 LYS CA . 26318 1 479 . 1 . 1 137 137 LYS CB C 13 33.178 0.000 . 1 . . . . . 231 LYS CB . 26318 1 480 . 1 . 1 137 137 LYS N N 15 125.324 0.038 . 1 . . . . . 231 LYS N . 26318 1 481 . 1 . 1 138 138 GLY H H 1 8.655 0.006 . 1 . . . . . 232 GLY H . 26318 1 482 . 1 . 1 138 138 GLY CA C 13 45.776 0.061 . 1 . . . . . 232 GLY CA . 26318 1 483 . 1 . 1 138 138 GLY N N 15 106.427 0.063 . 1 . . . . . 232 GLY N . 26318 1 484 . 1 . 1 139 139 PHE H H 1 8.055 0.004 . 1 . . . . . 233 PHE H . 26318 1 485 . 1 . 1 139 139 PHE CA C 13 54.7 0.073 . 1 . . . . . 233 PHE CA . 26318 1 486 . 1 . 1 139 139 PHE N N 15 120.413 0.020 . 1 . . . . . 233 PHE N . 26318 1 487 . 1 . 1 140 140 GLY H H 1 9.252 0.005 . 1 . . . . . 234 GLY H . 26318 1 488 . 1 . 1 140 140 GLY CA C 13 46.023 0.074 . 1 . . . . . 234 GLY CA . 26318 1 489 . 1 . 1 140 140 GLY N N 15 107.702 0.015 . 1 . . . . . 234 GLY N . 26318 1 490 . 1 . 1 141 141 PHE H H 1 8.86 0.005 . 1 . . . . . 235 PHE H . 26318 1 491 . 1 . 1 141 141 PHE CA C 13 56.673 0.020 . 1 . . . . . 235 PHE CA . 26318 1 492 . 1 . 1 141 141 PHE N N 15 116.033 0.035 . 1 . . . . . 235 PHE N . 26318 1 493 . 1 . 1 142 142 VAL H H 1 8.73 0.003 . 1 . . . . . 236 VAL H . 26318 1 494 . 1 . 1 142 142 VAL CA C 13 61.396 0.018 . 1 . . . . . 236 VAL CA . 26318 1 495 . 1 . 1 142 142 VAL N N 15 121.54 0.002 . 1 . . . . . 236 VAL N . 26318 1 496 . 1 . 1 143 143 SER H H 1 8.508 0.001 . 1 . . . . . 237 SER H . 26318 1 497 . 1 . 1 143 143 SER CA C 13 56.085 0.000 . 1 . . . . . 237 SER CA . 26318 1 498 . 1 . 1 143 143 SER CB C 13 64.073 0.000 . 1 . . . . . 237 SER CB . 26318 1 499 . 1 . 1 143 143 SER N N 15 121.429 0.038 . 1 . . . . . 237 SER N . 26318 1 500 . 1 . 1 144 144 PHE H H 1 8.874 0.002 . 1 . . . . . 238 PHE H . 26318 1 501 . 1 . 1 144 144 PHE CA C 13 59.636 0.078 . 1 . . . . . 238 PHE CA . 26318 1 502 . 1 . 1 144 144 PHE CB C 13 40.322 0.000 . 1 . . . . . 238 PHE CB . 26318 1 503 . 1 . 1 144 144 PHE N N 15 125.467 0.037 . 1 . . . . . 238 PHE N . 26318 1 504 . 1 . 1 145 145 GLU H H 1 8.181 0.004 . 1 . . . . . 239 GLU H . 26318 1 505 . 1 . 1 145 145 GLU CA C 13 59.802 0.030 . 1 . . . . . 239 GLU CA . 26318 1 506 . 1 . 1 145 145 GLU N N 15 119.352 0.081 . 1 . . . . . 239 GLU N . 26318 1 507 . 1 . 1 146 146 ARG H H 1 9.279 0.003 . 1 . . . . . 240 ARG H . 26318 1 508 . 1 . 1 146 146 ARG CA C 13 54.826 0.061 . 1 . . . . . 240 ARG CA . 26318 1 509 . 1 . 1 146 146 ARG N N 15 116.069 0.049 . 1 . . . . . 240 ARG N . 26318 1 510 . 1 . 1 147 147 HIS H H 1 9.003 0.004 . 1 . . . . . 241 HIS H . 26318 1 511 . 1 . 1 147 147 HIS CA C 13 58.82 0.047 . 1 . . . . . 241 HIS CA . 26318 1 512 . 1 . 1 147 147 HIS CB C 13 28.897 0.000 . 1 . . . . . 241 HIS CB . 26318 1 513 . 1 . 1 147 147 HIS N N 15 124.572 0.022 . 1 . . . . . 241 HIS N . 26318 1 514 . 1 . 1 148 148 GLU H H 1 9.728 0.006 . 1 . . . . . 242 GLU H . 26318 1 515 . 1 . 1 148 148 GLU CA C 13 59.91 0.082 . 1 . . . . . 242 GLU CA . 26318 1 516 . 1 . 1 148 148 GLU CB C 13 28.62 0.037 . 1 . . . . . 242 GLU CB . 26318 1 517 . 1 . 1 148 148 GLU N N 15 119.748 0.027 . 1 . . . . . 242 GLU N . 26318 1 518 . 1 . 1 149 149 ASP H H 1 6.547 0.003 . 1 . . . . . 243 ASP H . 26318 1 519 . 1 . 1 149 149 ASP CA C 13 56.521 0.068 . 1 . . . . . 243 ASP CA . 26318 1 520 . 1 . 1 149 149 ASP CB C 13 39.87 0.000 . 1 . . . . . 243 ASP CB . 26318 1 521 . 1 . 1 149 149 ASP N N 15 121.369 0.036 . 1 . . . . . 243 ASP N . 26318 1 522 . 1 . 1 150 150 ALA H H 1 6.717 0.005 . 1 . . . . . 244 ALA H . 26318 1 523 . 1 . 1 150 150 ALA CA C 13 54.489 0.098 . 1 . . . . . 244 ALA CA . 26318 1 524 . 1 . 1 150 150 ALA CB C 13 18.614 0.000 . 1 . . . . . 244 ALA CB . 26318 1 525 . 1 . 1 150 150 ALA N N 15 121.649 0.022 . 1 . . . . . 244 ALA N . 26318 1 526 . 1 . 1 151 151 GLN H H 1 7.781 0.003 . 1 . . . . . 245 GLN H . 26318 1 527 . 1 . 1 151 151 GLN CA C 13 58.129 0.063 . 1 . . . . . 245 GLN CA . 26318 1 528 . 1 . 1 151 151 GLN CB C 13 28.398 0.000 . 1 . . . . . 245 GLN CB . 26318 1 529 . 1 . 1 151 151 GLN N N 15 114.897 0.031 . 1 . . . . . 245 GLN N . 26318 1 530 . 1 . 1 152 152 LYS H H 1 7.269 0.004 . 1 . . . . . 246 LYS H . 26318 1 531 . 1 . 1 152 152 LYS CA C 13 59.351 0.094 . 1 . . . . . 246 LYS CA . 26318 1 532 . 1 . 1 152 152 LYS CB C 13 32.312 0.000 . 1 . . . . . 246 LYS CB . 26318 1 533 . 1 . 1 152 152 LYS N N 15 119.237 0.032 . 1 . . . . . 246 LYS N . 26318 1 534 . 1 . 1 153 153 ALA H H 1 7.46 0.003 . 1 . . . . . 247 ALA H . 26318 1 535 . 1 . 1 153 153 ALA CA C 13 54.666 0.081 . 1 . . . . . 247 ALA CA . 26318 1 536 . 1 . 1 153 153 ALA CB C 13 18.941 0.054 . 1 . . . . . 247 ALA CB . 26318 1 537 . 1 . 1 153 153 ALA N N 15 120.323 0.029 . 1 . . . . . 247 ALA N . 26318 1 538 . 1 . 1 154 154 VAL H H 1 7.616 0.003 . 1 . . . . . 248 VAL H . 26318 1 539 . 1 . 1 154 154 VAL CA C 13 66.842 0.078 . 1 . . . . . 248 VAL CA . 26318 1 540 . 1 . 1 154 154 VAL N N 15 117.278 0.049 . 1 . . . . . 248 VAL N . 26318 1 541 . 1 . 1 155 155 ASP H H 1 8.363 0.007 . 1 . . . . . 249 ASP H . 26318 1 542 . 1 . 1 155 155 ASP CA C 13 57.391 0.048 . 1 . . . . . 249 ASP CA . 26318 1 543 . 1 . 1 155 155 ASP CB C 13 40.519 0.000 . 1 . . . . . 249 ASP CB . 26318 1 544 . 1 . 1 155 155 ASP N N 15 118.489 0.050 . 1 . . . . . 249 ASP N . 26318 1 545 . 1 . 1 156 156 GLU H H 1 8.256 0.007 . 1 . . . . . 250 GLU H . 26318 1 546 . 1 . 1 156 156 GLU CA C 13 58.23 0.068 . 1 . . . . . 250 GLU CA . 26318 1 547 . 1 . 1 156 156 GLU CB C 13 30.765 0.002 . 1 . . . . . 250 GLU CB . 26318 1 548 . 1 . 1 156 156 GLU N N 15 115.835 0.041 . 1 . . . . . 250 GLU N . 26318 1 549 . 1 . 1 157 157 MET H H 1 7.95 0.006 . 1 . . . . . 251 MET H . 26318 1 550 . 1 . 1 157 157 MET CA C 13 54.571 0.024 . 1 . . . . . 251 MET CA . 26318 1 551 . 1 . 1 157 157 MET N N 15 112.994 0.099 . 1 . . . . . 251 MET N . 26318 1 552 . 1 . 1 158 158 ASN H H 1 7.912 0.002 . 1 . . . . . 252 ASN H . 26318 1 553 . 1 . 1 158 158 ASN CA C 13 56.841 0.049 . 1 . . . . . 252 ASN CA . 26318 1 554 . 1 . 1 158 158 ASN CB C 13 38.496 0.000 . 1 . . . . . 252 ASN CB . 26318 1 555 . 1 . 1 158 158 ASN N N 15 115.901 0.036 . 1 . . . . . 252 ASN N . 26318 1 556 . 1 . 1 159 159 GLY H H 1 8.742 0.004 . 1 . . . . . 253 GLY H . 26318 1 557 . 1 . 1 159 159 GLY CA C 13 45.876 0.050 . 1 . . . . . 253 GLY CA . 26318 1 558 . 1 . 1 159 159 GLY N N 15 116.954 0.106 . 1 . . . . . 253 GLY N . 26318 1 559 . 1 . 1 160 160 LYS H H 1 7.709 0.004 . 1 . . . . . 254 LYS H . 26318 1 560 . 1 . 1 160 160 LYS CA C 13 56.081 0.000 . 1 . . . . . 254 LYS CA . 26318 1 561 . 1 . 1 160 160 LYS N N 15 121.467 0.027 . 1 . . . . . 254 LYS N . 26318 1 562 . 1 . 1 161 161 GLU CA C 13 55.851 0.145 . 1 . . . . . 255 GLU CA . 26318 1 563 . 1 . 1 161 161 GLU CB C 13 30.819 0.000 . 1 . . . . . 255 GLU CB . 26318 1 564 . 1 . 1 162 162 LEU H H 1 9.023 0.002 . 1 . . . . . 256 LEU H . 26318 1 565 . 1 . 1 162 162 LEU CA C 13 54.256 0.052 . 1 . . . . . 256 LEU CA . 26318 1 566 . 1 . 1 162 162 LEU N N 15 127.489 0.062 . 1 . . . . . 256 LEU N . 26318 1 567 . 1 . 1 163 163 ASN H H 1 9.445 0.003 . 1 . . . . . 257 ASN H . 26318 1 568 . 1 . 1 163 163 ASN CA C 13 54.265 0.125 . 1 . . . . . 257 ASN CA . 26318 1 569 . 1 . 1 163 163 ASN N N 15 123.854 0.021 . 1 . . . . . 257 ASN N . 26318 1 570 . 1 . 1 164 164 GLY H H 1 8.753 0.005 . 1 . . . . . 258 GLY H . 26318 1 571 . 1 . 1 164 164 GLY CA C 13 45.671 0.081 . 1 . . . . . 258 GLY CA . 26318 1 572 . 1 . 1 164 164 GLY N N 15 103.457 0.038 . 1 . . . . . 258 GLY N . 26318 1 573 . 1 . 1 165 165 LYS H H 1 7.678 0.003 . 1 . . . . . 259 LYS H . 26318 1 574 . 1 . 1 165 165 LYS CA C 13 54.609 0.053 . 1 . . . . . 259 LYS CA . 26318 1 575 . 1 . 1 165 165 LYS CB C 13 35.114 0.025 . 1 . . . . . 259 LYS CB . 26318 1 576 . 1 . 1 165 165 LYS N N 15 120.423 0.034 . 1 . . . . . 259 LYS N . 26318 1 577 . 1 . 1 166 166 GLN H H 1 8.523 0.004 . 1 . . . . . 260 GLN H . 26318 1 578 . 1 . 1 166 166 GLN CA C 13 55.789 0.022 . 1 . . . . . 260 GLN CA . 26318 1 579 . 1 . 1 166 166 GLN CB C 13 29.505 0.000 . 1 . . . . . 260 GLN CB . 26318 1 580 . 1 . 1 166 166 GLN N N 15 121.699 0.035 . 1 . . . . . 260 GLN N . 26318 1 581 . 1 . 1 167 167 ILE H H 1 8.666 0.005 . 1 . . . . . 261 ILE H . 26318 1 582 . 1 . 1 167 167 ILE CA C 13 60.997 0.187 . 1 . . . . . 261 ILE CA . 26318 1 583 . 1 . 1 167 167 ILE CB C 13 39.979 0.003 . 1 . . . . . 261 ILE CB . 26318 1 584 . 1 . 1 167 167 ILE N N 15 121.982 0.065 . 1 . . . . . 261 ILE N . 26318 1 585 . 1 . 1 168 168 TYR H H 1 8.43 0.010 . 1 . . . . . 262 TYR H . 26318 1 586 . 1 . 1 168 168 TYR CA C 13 55.989 0.047 . 1 . . . . . 262 TYR CA . 26318 1 587 . 1 . 1 168 168 TYR N N 15 123.556 0.063 . 1 . . . . . 262 TYR N . 26318 1 588 . 1 . 1 169 169 VAL H H 1 8.035 0.007 . 1 . . . . . 263 VAL H . 26318 1 589 . 1 . 1 169 169 VAL CA C 13 60.357 0.031 . 1 . . . . . 263 VAL CA . 26318 1 590 . 1 . 1 169 169 VAL N N 15 126.245 0.046 . 1 . . . . . 263 VAL N . 26318 1 591 . 1 . 1 170 170 GLY H H 1 8.415 0.002 . 1 . . . . . 264 GLY H . 26318 1 592 . 1 . 1 170 170 GLY CA C 13 45.236 0.088 . 1 . . . . . 264 GLY CA . 26318 1 593 . 1 . 1 170 170 GLY N N 15 111.266 0.027 . 1 . . . . . 264 GLY N . 26318 1 594 . 1 . 1 171 171 ARG CA C 13 56.27 0.000 . 1 . . . . . 265 ARG CA . 26318 1 595 . 1 . 1 171 171 ARG CB C 13 30.95 0.000 . 1 . . . . . 265 ARG CB . 26318 1 596 . 1 . 1 172 172 ALA H H 1 8.345 0.002 . 1 . . . . . 266 ALA H . 26318 1 597 . 1 . 1 172 172 ALA CB C 13 19.264 0.000 . 1 . . . . . 266 ALA CB . 26318 1 598 . 1 . 1 172 172 ALA N N 15 125.002 0.042 . 1 . . . . . 266 ALA N . 26318 1 599 . 1 . 1 174 174 LYS CA C 13 56.497 0.063 . 1 . . . . . 268 LYS CA . 26318 1 600 . 1 . 1 175 175 LYS H H 1 8.332 0.004 . 1 . . . . . 269 LYS H . 26318 1 601 . 1 . 1 175 175 LYS CA C 13 56.66 0.084 . 1 . . . . . 269 LYS CA . 26318 1 602 . 1 . 1 175 175 LYS CB C 13 33.139 0.020 . 1 . . . . . 269 LYS CB . 26318 1 603 . 1 . 1 175 175 LYS N N 15 123.466 0.017 . 1 . . . . . 269 LYS N . 26318 1 604 . 1 . 1 176 176 VAL H H 1 8.113 0.003 . 1 . . . . . 270 VAL H . 26318 1 605 . 1 . 1 176 176 VAL CA C 13 62.441 0.081 . 1 . . . . . 270 VAL CA . 26318 1 606 . 1 . 1 176 176 VAL CB C 13 32.756 0.079 . 1 . . . . . 270 VAL CB . 26318 1 607 . 1 . 1 176 176 VAL N N 15 122.347 0.010 . 1 . . . . . 270 VAL N . 26318 1 608 . 1 . 1 177 177 GLU H H 1 8.413 0.003 . 1 . . . . . 271 GLU H . 26318 1 609 . 1 . 1 177 177 GLU CA C 13 56.514 0.069 . 1 . . . . . 271 GLU CA . 26318 1 610 . 1 . 1 177 177 GLU CB C 13 30.538 0.000 . 1 . . . . . 271 GLU CB . 26318 1 611 . 1 . 1 177 177 GLU N N 15 125.339 0.026 . 1 . . . . . 271 GLU N . 26318 1 612 . 1 . 1 178 178 ARG H H 1 8.382 0.003 . 1 . . . . . 272 ARG H . 26318 1 613 . 1 . 1 178 178 ARG CA C 13 56.477 0.068 . 1 . . . . . 272 ARG CA . 26318 1 614 . 1 . 1 178 178 ARG CB C 13 30.797 0.054 . 1 . . . . . 272 ARG CB . 26318 1 615 . 1 . 1 178 178 ARG N N 15 122.23 0.023 . 1 . . . . . 272 ARG N . 26318 1 616 . 1 . 1 179 179 GLN H H 1 8.531 0.006 . 1 . . . . . 273 GLN H . 26318 1 617 . 1 . 1 179 179 GLN CA C 13 56.577 0.114 . 1 . . . . . 273 GLN CA . 26318 1 618 . 1 . 1 179 179 GLN CB C 13 29.303 0.023 . 1 . . . . . 273 GLN CB . 26318 1 619 . 1 . 1 179 179 GLN N N 15 121.641 0.028 . 1 . . . . . 273 GLN N . 26318 1 620 . 1 . 1 180 180 THR H H 1 8.138 0.003 . 1 . . . . . 274 THR H . 26318 1 621 . 1 . 1 180 180 THR CA C 13 62.864 0.067 . 1 . . . . . 274 THR CA . 26318 1 622 . 1 . 1 180 180 THR CB C 13 69.615 0.033 . 1 . . . . . 274 THR CB . 26318 1 623 . 1 . 1 180 180 THR N N 15 115.366 0.028 . 1 . . . . . 274 THR N . 26318 1 624 . 1 . 1 181 181 GLU H H 1 8.359 0.003 . 1 . . . . . 275 GLU H . 26318 1 625 . 1 . 1 181 181 GLU CA C 13 57.102 0.043 . 1 . . . . . 275 GLU CA . 26318 1 626 . 1 . 1 181 181 GLU CB C 13 30.204 0.020 . 1 . . . . . 275 GLU CB . 26318 1 627 . 1 . 1 181 181 GLU N N 15 123.154 0.026 . 1 . . . . . 275 GLU N . 26318 1 628 . 1 . 1 182 182 LEU H H 1 8.163 0.003 . 1 . . . . . 276 LEU H . 26318 1 629 . 1 . 1 182 182 LEU CA C 13 55.925 0.072 . 1 . . . . . 276 LEU CA . 26318 1 630 . 1 . 1 182 182 LEU CB C 13 42.216 0.015 . 1 . . . . . 276 LEU CB . 26318 1 631 . 1 . 1 182 182 LEU N N 15 122.936 0.019 . 1 . . . . . 276 LEU N . 26318 1 632 . 1 . 1 183 183 LYS H H 1 8.158 0.003 . 1 . . . . . 277 LYS H . 26318 1 633 . 1 . 1 183 183 LYS CA C 13 56.924 0.064 . 1 . . . . . 277 LYS CA . 26318 1 634 . 1 . 1 183 183 LYS CB C 13 32.818 0.005 . 1 . . . . . 277 LYS CB . 26318 1 635 . 1 . 1 183 183 LYS N N 15 121.511 0.027 . 1 . . . . . 277 LYS N . 26318 1 636 . 1 . 1 184 184 ARG H H 1 8.154 0.004 . 1 . . . . . 278 ARG H . 26318 1 637 . 1 . 1 184 184 ARG CA C 13 56.621 0.000 . 1 . . . . . 278 ARG CA . 26318 1 638 . 1 . 1 184 184 ARG CB C 13 30.783 0.035 . 1 . . . . . 278 ARG CB . 26318 1 639 . 1 . 1 184 184 ARG N N 15 121.434 0.013 . 1 . . . . . 278 ARG N . 26318 1 640 . 1 . 1 185 185 LYS H H 1 8.179 0.003 . 1 . . . . . 279 LYS H . 26318 1 641 . 1 . 1 185 185 LYS CA C 13 57.005 0.067 . 1 . . . . . 279 LYS CA . 26318 1 642 . 1 . 1 185 185 LYS CB C 13 32.957 0.022 . 1 . . . . . 279 LYS CB . 26318 1 643 . 1 . 1 185 185 LYS N N 15 121.824 0.014 . 1 . . . . . 279 LYS N . 26318 1 644 . 1 . 1 186 186 PHE H H 1 8.19 0.004 . 1 . . . . . 280 PHE H . 26318 1 645 . 1 . 1 186 186 PHE CA C 13 58.437 0.069 . 1 . . . . . 280 PHE CA . 26318 1 646 . 1 . 1 186 186 PHE CB C 13 39.393 0.004 . 1 . . . . . 280 PHE CB . 26318 1 647 . 1 . 1 186 186 PHE N N 15 120.566 0.013 . 1 . . . . . 280 PHE N . 26318 1 648 . 1 . 1 187 187 GLU H H 1 8.271 0.002 . 1 . . . . . 281 GLU H . 26318 1 649 . 1 . 1 187 187 GLU CA C 13 57.071 0.068 . 1 . . . . . 281 GLU CA . 26318 1 650 . 1 . 1 187 187 GLU CB C 13 30.378 0.014 . 1 . . . . . 281 GLU CB . 26318 1 651 . 1 . 1 187 187 GLU N N 15 121.722 0.014 . 1 . . . . . 281 GLU N . 26318 1 652 . 1 . 1 188 188 GLN H H 1 8.223 0.002 . 1 . . . . . 282 GLN H . 26318 1 653 . 1 . 1 188 188 GLN CB C 13 29.357 0.000 . 1 . . . . . 282 GLN CB . 26318 1 654 . 1 . 1 188 188 GLN N N 15 120.511 0.021 . 1 . . . . . 282 GLN N . 26318 1 655 . 1 . 1 190 190 LYS H H 1 8.185 0.000 . 1 . . . . . 284 LYS H . 26318 1 656 . 1 . 1 190 190 LYS CA C 13 62.593 0.000 . 1 . . . . . 284 LYS CA . 26318 1 657 . 1 . 1 190 190 LYS CB C 13 32.992 0.005 . 1 . . . . . 284 LYS CB . 26318 1 658 . 1 . 1 190 190 LYS N N 15 122.285 0.000 . 1 . . . . . 284 LYS N . 26318 1 659 . 1 . 1 191 191 GLN H H 1 8.335 0.005 . 1 . . . . . 285 GLN H . 26318 1 660 . 1 . 1 191 191 GLN CA C 13 56.044 0.041 . 1 . . . . . 285 GLN CA . 26318 1 661 . 1 . 1 191 191 GLN CB C 13 29.599 0.000 . 1 . . . . . 285 GLN CB . 26318 1 662 . 1 . 1 191 191 GLN N N 15 121.304 0.030 . 1 . . . . . 285 GLN N . 26318 1 663 . 1 . 1 192 192 ASP H H 1 8.329 0.004 . 1 . . . . . 286 ASP H . 26318 1 664 . 1 . 1 192 192 ASP CA C 13 54.568 0.021 . 1 . . . . . 286 ASP CA . 26318 1 665 . 1 . 1 192 192 ASP CB C 13 41.202 0.007 . 1 . . . . . 286 ASP CB . 26318 1 666 . 1 . 1 192 192 ASP N N 15 121.434 0.033 . 1 . . . . . 286 ASP N . 26318 1 667 . 1 . 1 193 193 ARG H H 1 8.116 0.003 . 1 . . . . . 287 ARG H . 26318 1 668 . 1 . 1 193 193 ARG CA C 13 56.008 0.055 . 1 . . . . . 287 ARG CA . 26318 1 669 . 1 . 1 193 193 ARG CB C 13 30.994 0.021 . 1 . . . . . 287 ARG CB . 26318 1 670 . 1 . 1 193 193 ARG N N 15 120.421 0.024 . 1 . . . . . 287 ARG N . 26318 1 671 . 1 . 1 194 194 ILE H H 1 8.238 0.002 . 1 . . . . . 288 ILE H . 26318 1 672 . 1 . 1 194 194 ILE CA C 13 61.525 0.068 . 1 . . . . . 288 ILE CA . 26318 1 673 . 1 . 1 194 194 ILE CB C 13 38.653 0.002 . 1 . . . . . 288 ILE CB . 26318 1 674 . 1 . 1 194 194 ILE N N 15 122.696 0.020 . 1 . . . . . 288 ILE N . 26318 1 675 . 1 . 1 195 195 THR H H 1 7.756 0.002 . 1 . . . . . 289 THR H . 26318 1 676 . 1 . 1 195 195 THR CA C 13 63.266 0.044 . 1 . . . . . 289 THR CA . 26318 1 677 . 1 . 1 195 195 THR CB C 13 70.838 0.000 . 1 . . . . . 289 THR CB . 26318 1 678 . 1 . 1 195 195 THR N N 15 123.319 0.020 . 1 . . . . . 289 THR N . 26318 1 stop_ save_