data_25426

#######################
#  Entry information  #
#######################

save_entry_information
   _Saveframe_category      entry_information

   _Entry_title
;
MBD2 intrinsically disordered region
;
   _BMRB_accession_number   25426
   _BMRB_flat_file_name     bmr25426.str
   _Entry_type              original
   _Submission_date         2015-01-12
   _Accession_date          2015-01-12
   _Entry_origination       author
   _NMR_STAR_version        2.1.1
   _Experimental_method     NMR
   _Details                 .

   loop_
      _Author_ordinal
      _Author_family_name
      _Author_given_name
      _Author_middle_initials
      _Author_family_title

      1 Williams David C. Jr.

   stop_

   loop_
      _Saveframe_category_type
      _Saveframe_category_type_count

      assigned_chemical_shifts 1

   stop_

   loop_
      _Data_type
      _Data_type_count

      "1H chemical shifts"  350
      "13C chemical shifts" 331
      "15N chemical shifts" 106

   stop_

   loop_
      _Revision_date
      _Revision_keyword
      _Revision_author
      _Revision_detail

      2018-02-23 original BMRB .

   stop_

   _Original_release_date   2015-01-12

save_


#############################
#  Citation for this entry  #
#############################

save_entry_citation
   _Saveframe_category           entry_citation

   _Citation_full                .
   _Citation_title
;
An intrinsically disordered region of methyl-CpG binding domain protein 2 (MBD2) recruits the histone deacetylase core of the NuRD complex
;
   _Citation_status              published
   _Citation_type                journal
   _CAS_abstract_code            .
   _MEDLINE_UI_code              .
   _PubMed_ID                    25753662

   loop_
      _Author_ordinal
      _Author_family_name
      _Author_given_name
      _Author_middle_initials
      _Author_family_title

      1 Desai      Megha   A. .
      2 Webb       Heather D. .
      3 Sinanan    Leander M. .
      4 Scarsdale  Neel    .  .
      5 Walavalkar Ninad   M. .
      6 Ginder     Gordon  G. .
      7 Williams   David   C. Jr.

   stop_

   _Journal_abbreviation        'Nucleic Acids Res.'
   _Journal_name_full           'Nucleic acids research'
   _Journal_volume               43
   _Journal_issue                6
   _Journal_ISSN                 1362-4962
   _Journal_CSD                  .
   _Book_chapter_title           .
   _Book_volume                  .
   _Book_series                  .
   _Book_ISBN                    .
   _Conference_state_province    .
   _Conference_abstract_number   .
   _Page_first                   3100
   _Page_last                    3113
   _Year                         2015
   _Details                      .

save_


##################################
#  Molecular system description  #
##################################

save_assembly
   _Saveframe_category         molecular_system

   _Mol_system_name           'MBD2 IDR'
   _Enzyme_commission_number   .

   loop_
      _Mol_system_component_name
      _Mol_label

      'MBD2 IDR' $MBD2

   stop_

   _System_molecular_weight    13046.7
   _System_physical_state      native
   _System_oligomer_state      ?
   _System_paramagnetic        no
   _System_thiol_state         .
   _Database_query_date        .
   _Details                    .

save_


    ########################
    #  Monomeric polymers  #
    ########################

save_MBD2
   _Saveframe_category                          monomeric_polymer

   _Mol_type                                    polymer
   _Mol_polymer_class                           protein
   _Name_common                                 MBD2
   _Molecular_mass                              .
   _Mol_thiol_state                            'all free'
   _Details                                     .

   	##############################
   	#  Polymer residue sequence  #
   	##############################

      _Residue_count                               121
   _Mol_residue_sequence
;
GSDLNTTLPIRQTASIFKQP
VTKVTNHPSNKVKSDPQRMN
EQPRQLFWEKRLQGLSASDV
TEQIIKTMELPKGLQGVGPG
SNDETLLSAVASALHTSSAP
ITGQVSAAVEKNPAVWLNTS
Q
;

   loop_
      _Residue_seq_code
      _Residue_author_seq_code
      _Residue_label

        1 236 GLY    2 237 SER    3 238 ASP    4 239 LEU    5 240 ASN
        6 241 THR    7 242 THR    8 243 LEU    9 244 PRO   10 245 ILE
       11 246 ARG   12 247 GLN   13 248 THR   14 249 ALA   15 250 SER
       16 251 ILE   17 252 PHE   18 253 LYS   19 254 GLN   20 255 PRO
       21 256 VAL   22 257 THR   23 258 LYS   24 259 VAL   25 260 THR
       26 261 ASN   27 262 HIS   28 263 PRO   29 264 SER   30 265 ASN
       31 266 LYS   32 267 VAL   33 268 LYS   34 269 SER   35 270 ASP
       36 271 PRO   37 272 GLN   38 273 ARG   39 274 MET   40 275 ASN
       41 276 GLU   42 277 GLN   43 278 PRO   44 279 ARG   45 280 GLN
       46 281 LEU   47 282 PHE   48 283 TRP   49 284 GLU   50 285 LYS
       51 286 ARG   52 287 LEU   53 288 GLN   54 289 GLY   55 290 LEU
       56 291 SER   57 292 ALA   58 293 SER   59 294 ASP   60 295 VAL
       61 296 THR   62 297 GLU   63 298 GLN   64 299 ILE   65 300 ILE
       66 301 LYS   67 302 THR   68 303 MET   69 304 GLU   70 305 LEU
       71 306 PRO   72 307 LYS   73 308 GLY   74 309 LEU   75 310 GLN
       76 311 GLY   77 312 VAL   78 313 GLY   79 314 PRO   80 315 GLY
       81 316 SER   82 317 ASN   83 318 ASP   84 319 GLU   85 320 THR
       86 321 LEU   87 322 LEU   88 323 SER   89 324 ALA   90 325 VAL
       91 326 ALA   92 327 SER   93 328 ALA   94 329 LEU   95 330 HIS
       96 331 THR   97 332 SER   98 333 SER   99 334 ALA  100 335 PRO
      101 336 ILE  102 337 THR  103 338 GLY  104 339 GLN  105 340 VAL
      106 341 SER  107 342 ALA  108 343 ALA  109 344 VAL  110 345 GLU
      111 346 LYS  112 347 ASN  113 348 PRO  114 349 ALA  115 350 VAL
      116 351 TRP  117 352 LEU  118 353 ASN  119 354 THR  120 355 SER
      121 356 GLN

   stop_

   _Sequence_homology_query_date                .
   _Sequence_homology_query_revised_last_date   .

save_


    ####################
    #  Natural source  #
    ####################

save_natural_source
   _Saveframe_category   natural_source


   loop_
      _Mol_label
      _Organism_name_common
      _NCBI_taxonomy_ID
      _Superkingdom
      _Kingdom
      _Genus
      _Species

      $MBD2 Human 9606 Eukaryota Metazoa Homo sapiens

   stop_

save_


    #########################
    #  Experimental source  #
    #########################

save_experimental_source
   _Saveframe_category   experimental_source


   loop_
      _Mol_label
      _Production_method
      _Host_organism_name_common
      _Genus
      _Species
      _Strain
      _Vector_name

      $MBD2 'recombinant technology' . Escherichia coli . pet32a

   stop_

save_


#####################################
#  Sample contents and methodology  #
#####################################

    ########################
    #  Sample description  #
    ########################

save_sample_1
   _Saveframe_category   sample

   _Sample_type          solution
   _Details              .

   loop_
      _Mol_label
      _Concentration_value
      _Concentration_value_units
      _Concentration_min_value
      _Concentration_max_value
      _Isotopic_labeling

      $MBD2            .   mM 0.5 1 '[U-99% 13C; U-99% 15N]'
       H2O           90    %   .   . 'natural abundance'
       D2O           10    %   .   . 'natural abundance'
       NaH2PO4       10    mM  .   . 'natural abundance'
      'sodium azide'  0.02 %   .   . 'natural abundance'
       DTT            1    mM  .   . 'natural abundance'

   stop_

save_


############################
#  Computer software used  #
############################

save_NMRPipe
   _Saveframe_category   software

   _Name                 NMRPipe
   _Version              .

   loop_
      _Vendor
      _Address
      _Electronic_address

      'Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax' . .

   stop_

   loop_
      _Task

      processing

   stop_

   _Details              .

save_


save_CcpNMR
   _Saveframe_category   software

   _Name                 CcpNMR
   _Version              .

   loop_
      _Vendor
      _Address
      _Electronic_address

      CCPN . .

   stop_

   loop_
      _Task

      'chemical shift assignment'

   stop_

   _Details              .

save_


#########################
#  Experimental detail  #
#########################

    ##################################
    #  NMR Spectrometer definitions  #
    ##################################

save_spectrometer_1
   _Saveframe_category   NMR_spectrometer

   _Manufacturer         Bruker
   _Model                Avance
   _Field_strength       700
   _Details              .

save_


    #############################
    #  NMR applied experiments  #
    #############################

save_2D_1H-15N_HSQC_1
   _Saveframe_category   NMR_applied_experiment

   _Experiment_name     '2D 1H-15N HSQC'
   _Sample_label        $sample_1

save_


save_3D_HNCO_2
   _Saveframe_category   NMR_applied_experiment

   _Experiment_name     '3D HNCO'
   _Sample_label        $sample_1

save_


save_3D_HNCACB_3
   _Saveframe_category   NMR_applied_experiment

   _Experiment_name     '3D HNCACB'
   _Sample_label        $sample_1

save_


save_3D_CBCA(CO)NH_4
   _Saveframe_category   NMR_applied_experiment

   _Experiment_name     '3D CBCA(CO)NH'
   _Sample_label        $sample_1

save_


save_3D_HBHA(CO)NH_5
   _Saveframe_category   NMR_applied_experiment

   _Experiment_name     '3D HBHA(CO)NH'
   _Sample_label        $sample_1

save_


save_3D_1H-15N_NOESY_6
   _Saveframe_category   NMR_applied_experiment

   _Experiment_name     '3D 1H-15N NOESY'
   _Sample_label        $sample_1

save_


#######################
#  Sample conditions  #
#######################

save_sample_conditions_1
   _Saveframe_category   sample_conditions

   _Details              .

   loop_
      _Variable_type
      _Variable_value
      _Variable_value_error
      _Variable_value_units

      'ionic strength'  25   . mM
       pH                6.5 . pH
       pressure          1   . atm
       temperature     298   . K

   stop_

save_


####################
#  NMR parameters  #
####################

    ##############################
    #  Assigned chemical shifts  #
    ##############################

	################################
	#  Chemical shift referencing  #
	################################

save_chemical_shift_reference_1
   _Saveframe_category   chemical_shift_reference

   _Details              .

   loop_
      _Mol_common_name
      _Atom_type
      _Atom_isotope_number
      _Atom_group
      _Chem_shift_units
      _Chem_shift_value
      _Reference_method
      _Reference_type
      _External_reference_sample_geometry
      _External_reference_location
      _External_reference_axis
      _Indirect_shift_ratio

      DSS C 13 'methyl protons' ppm 0.00 na       indirect . 'separate tube (no insert) similar to the experimental sample tube' . 0.251449530
      DSS H  1 'methyl protons' ppm 0.00 internal direct   . 'separate tube (no insert) similar to the experimental sample tube' . 1.000000000
      DSS N 15 'methyl protons' ppm 0.00 na       indirect . 'separate tube (no insert) similar to the experimental sample tube' . 0.101329118

   stop_

save_


	###################################
	#  Assigned chemical shift lists  #
	###################################

###################################################################
#       Chemical Shift Ambiguity Index Value Definitions          #
#                                                                 #
# The values other than 1 are used for those atoms with different #
# chemical shifts that cannot be assigned to stereospecific atoms #
# or to specific residues or chains.                              #
#                                                                 #
#   Index Value            Definition                             #
#                                                                 #
#      1             Unique (including isolated methyl protons,   #
#                         geminal atoms, and geminal methyl       #
#                         groups with identical chemical shifts)  #
#                         (e.g. ILE HD11, HD12, HD13 protons)     #
#      2             Ambiguity of geminal atoms or geminal methyl #
#                         proton groups (e.g. ASP HB2 and HB3     #
#                         protons, LEU CD1 and CD2 carbons, or    #
#                         LEU HD11, HD12, HD13 and HD21, HD22,    #
#                         HD23 methyl protons)                    #
#      3             Aromatic atoms on opposite sides of          #
#                         symmetrical rings (e.g. TYR HE1 and HE2 #
#                         protons)                                #
#      4             Intraresidue ambiguities (e.g. LYS HG and    #
#                         HD protons or TRP HZ2 and HZ3 protons)  #
#      5             Interresidue ambiguities (LYS 12 vs. LYS 27) #
#      6             Intermolecular ambiguities (e.g. ASP 31 CA   #
#                         in monomer 1 and ASP 31 CA in monomer 2 #
#                         of an asymmetrical homodimer, duplex    #
#                         DNA assignments, or other assignments   #
#                         that may apply to atoms in one or more  #
#                         molecule in the molecular assembly)     #
#      9             Ambiguous, specific ambiguity not defined    #
#                                                                 #
###################################################################
save_assigned_chem_shift_list_1
   _Saveframe_category               assigned_chemical_shifts

   _Details                          .

   loop_
      _Experiment_label

      '2D 1H-15N HSQC'
      '3D HNCO'
      '3D HNCACB'
      '3D CBCA(CO)NH'
      '3D HBHA(CO)NH'
      '3D 1H-15N NOESY'

   stop_

   loop_
      _Sample_label

      $sample_1

   stop_

   _Sample_conditions_label         $sample_conditions_1
   _Chem_shift_reference_set_label  $chemical_shift_reference_1
   _Mol_system_component_name       'MBD2 IDR'
   _Text_data_format                 .
   _Text_data                        .

   loop_
      _Atom_shift_assign_ID
      _Residue_author_seq_code
      _Residue_seq_code
      _Residue_label
      _Atom_name
      _Atom_type
      _Chem_shift_value
      _Chem_shift_value_error
      _Chem_shift_ambiguity_code

        1 237   2 SER HA  H   4.518 0.000 1
        2 237   2 SER HB2 H   3.866 0.000 1
        3 237   2 SER C   C 174.080 0.000 1
        4 237   2 SER CA  C  58.350 0.044 1
        5 237   2 SER CB  C  63.952 0.000 1
        6 238   3 ASP H   H   8.536 0.001 1
        7 238   3 ASP HA  H   4.603 0.000 1
        8 238   3 ASP HB2 H   2.721 0.000 2
        9 238   3 ASP HB3 H   2.616 0.000 2
       10 238   3 ASP C   C 176.244 0.000 1
       11 238   3 ASP CA  C  54.368 0.020 1
       12 238   3 ASP CB  C  41.035 0.035 1
       13 238   3 ASP N   N 122.506 0.051 1
       14 239   4 LEU H   H   8.264 0.002 1
       15 239   4 LEU HA  H   4.312 0.000 1
       16 239   4 LEU HB2 H   1.617 0.000 1
       17 239   4 LEU C   C 177.338 0.000 1
       18 239   4 LEU CA  C  55.485 0.000 1
       19 239   4 LEU CB  C  42.190 0.000 1
       20 239   4 LEU N   N 122.515 0.028 1
       21 240   5 ASN H   H   8.486 0.003 1
       22 240   5 ASN HA  H   4.744 0.000 1
       23 240   5 ASN HB2 H   2.798 0.000 2
       24 240   5 ASN HB3 H   2.874 0.000 2
       25 240   5 ASN C   C 175.527 0.000 1
       26 240   5 ASN CA  C  53.480 0.000 1
       27 240   5 ASN CB  C  38.731 0.038 1
       28 240   5 ASN N   N 119.236 0.028 1
       29 241   6 THR H   H   8.069 0.002 1
       30 241   6 THR HA  H   4.382 0.000 1
       31 241   6 THR HB  H   4.286 0.000 1
       32 241   6 THR C   C 174.672 0.000 1
       33 241   6 THR CA  C  62.011 0.022 1
       34 241   6 THR CB  C  69.634 0.014 1
       35 241   6 THR N   N 114.109 0.049 1
       36 242   7 THR H   H   8.144 0.001 1
       37 242   7 THR HA  H   4.315 0.000 1
       38 242   7 THR HB  H   4.188 0.000 1
       39 242   7 THR C   C 174.242 0.000 1
       40 242   7 THR CA  C  62.030 0.007 1
       41 242   7 THR CB  C  69.828 0.045 1
       42 242   7 THR N   N 116.757 0.030 1
       43 243   8 LEU H   H   8.193 0.001 1
       44 243   8 LEU CA  C  53.213 0.000 1
       45 243   8 LEU CB  C  41.786 0.000 1
       46 243   8 LEU N   N 126.291 0.010 1
       47 244   9 PRO HA  H   4.438 0.000 1
       48 244   9 PRO HB2 H   1.850 0.000 2
       49 244   9 PRO HB3 H   2.256 0.000 2
       50 244   9 PRO C   C 176.854 0.000 1
       51 244   9 PRO CA  C  63.037 0.000 1
       52 244   9 PRO CB  C  31.815 0.000 1
       53 245  10 ILE H   H   8.162 0.002 1
       54 245  10 ILE HA  H   4.100 0.000 1
       55 245  10 ILE HB  H   1.832 0.000 1
       56 245  10 ILE C   C 176.410 0.000 1
       57 245  10 ILE CA  C  61.310 0.016 1
       58 245  10 ILE CB  C  38.669 0.022 1
       59 245  10 ILE N   N 121.148 0.006 1
       60 246  11 ARG H   H   8.396 0.003 1
       61 246  11 ARG HA  H   4.356 0.000 1
       62 246  11 ARG HB2 H   1.764 0.000 2
       63 246  11 ARG HB3 H   1.812 0.000 2
       64 246  11 ARG C   C 176.085 0.000 1
       65 246  11 ARG CA  C  55.969 0.013 1
       66 246  11 ARG CB  C  30.814 0.002 1
       67 246  11 ARG N   N 125.228 0.042 1
       68 247  12 GLN H   H   8.491 0.001 1
       69 247  12 GLN HA  H   4.405 0.000 1
       70 247  12 GLN HB2 H   2.113 0.000 2
       71 247  12 GLN HB3 H   1.984 0.000 2
       72 247  12 GLN C   C 176.121 0.000 1
       73 247  12 GLN CA  C  55.868 0.031 1
       74 247  12 GLN CB  C  29.546 0.013 1
       75 247  12 GLN N   N 122.424 0.008 1
       76 248  13 THR H   H   8.237 0.001 1
       77 248  13 THR HA  H   4.322 0.000 1
       78 248  13 THR HB  H   4.215 0.000 1
       79 248  13 THR CA  C  61.943 0.040 1
       80 248  13 THR CB  C  69.915 0.033 1
       81 248  13 THR N   N 116.012 0.012 1
       82 249  14 ALA H   H   8.364 0.001 1
       83 249  14 ALA HA  H   4.361 0.000 1
       84 249  14 ALA HB  H   1.406 0.000 1
       85 249  14 ALA C   C 177.728 0.000 1
       86 249  14 ALA CA  C  52.606 0.000 1
       87 249  14 ALA CB  C  19.340 0.000 1
       88 249  14 ALA N   N 126.465 0.047 1
       89 250  15 SER H   H   8.304 0.001 1
       90 250  15 SER HA  H   4.411 0.000 1
       91 250  15 SER HB2 H   3.813 0.000 1
       92 250  15 SER C   C 174.552 0.000 1
       93 250  15 SER CA  C  58.406 0.057 1
       94 250  15 SER CB  C  63.823 0.000 1
       95 250  15 SER N   N 115.441 0.011 1
       96 251  16 ILE H   H   8.006 0.001 1
       97 251  16 ILE HA  H   4.140 0.000 1
       98 251  16 ILE HB  H   1.783 0.000 1
       99 251  16 ILE C   C 175.804 0.000 1
      100 251  16 ILE CA  C  61.328 0.046 1
      101 251  16 ILE CB  C  38.711 0.031 1
      102 251  16 ILE N   N 121.834 0.006 1
      103 252  17 PHE H   H   8.219 0.001 1
      104 252  17 PHE HA  H   4.613 0.000 1
      105 252  17 PHE HB2 H   2.984 0.000 2
      106 252  17 PHE HB3 H   3.101 0.000 2
      107 252  17 PHE C   C 175.248 0.000 1
      108 252  17 PHE CA  C  57.679 0.012 1
      109 252  17 PHE CB  C  39.592 0.018 1
      110 252  17 PHE N   N 124.133 0.033 1
      111 253  18 LYS H   H   8.098 0.001 1
      112 253  18 LYS HA  H   4.274 0.000 1
      113 253  18 LYS HB2 H   1.647 0.000 2
      114 253  18 LYS HB3 H   1.737 0.000 2
      115 253  18 LYS C   C 175.571 0.000 1
      116 253  18 LYS CA  C  55.711 0.016 1
      117 253  18 LYS CB  C  33.183 0.004 1
      118 253  18 LYS N   N 124.144 0.007 1
      119 254  19 GLN H   H   8.310 0.001 1
      120 254  19 GLN CA  C  53.804 0.000 1
      121 254  19 GLN CB  C  28.742 0.000 1
      122 254  19 GLN N   N 123.226 0.026 1
      123 255  20 PRO HA  H   4.456 0.000 1
      124 255  20 PRO HB2 H   2.287 0.000 2
      125 255  20 PRO HB3 H   1.896 0.000 2
      126 255  20 PRO C   C 176.782 0.000 1
      127 255  20 PRO CA  C  63.012 0.000 1
      128 255  20 PRO CB  C  32.117 0.000 1
      129 256  21 VAL H   H   8.308 0.001 1
      130 256  21 VAL HA  H   4.137 0.000 1
      131 256  21 VAL HB  H   2.062 0.000 1
      132 256  21 VAL C   C 176.461 0.000 1
      133 256  21 VAL CA  C  62.418 0.009 1
      134 256  21 VAL CB  C  32.676 0.011 1
      135 256  21 VAL N   N 120.837 0.018 1
      136 257  22 THR H   H   8.234 0.001 1
      137 257  22 THR HA  H   4.327 0.000 1
      138 257  22 THR HB  H   4.139 0.000 1
      139 257  22 THR CA  C  61.855 0.064 1
      140 257  22 THR CB  C  69.927 0.035 1
      141 257  22 THR N   N 119.047 0.034 1
      142 258  23 LYS H   H   8.365 0.001 1
      143 258  23 LYS HA  H   4.365 0.000 1
      144 258  23 LYS HB2 H   1.731 0.000 2
      145 258  23 LYS HB3 H   1.806 0.000 2
      146 258  23 LYS CA  C  56.201 0.030 1
      147 258  23 LYS CB  C  33.187 0.017 1
      148 258  23 LYS N   N 124.723 0.038 1
      149 259  24 VAL H   H   8.280 0.002 1
      150 259  24 VAL HA  H   4.164 0.000 1
      151 259  24 VAL HB  H   2.054 0.000 1
      152 259  24 VAL C   C 176.264 0.000 1
      153 259  24 VAL CA  C  62.309 0.005 1
      154 259  24 VAL CB  C  32.711 0.025 1
      155 259  24 VAL N   N 122.615 0.063 1
      156 260  25 THR H   H   8.295 0.002 1
      157 260  25 THR C   C 174.480 0.000 1
      158 260  25 THR CA  C  62.163 0.000 1
      159 260  25 THR CB  C  69.883 0.000 1
      160 260  25 THR N   N 118.606 0.045 1
      161 263  28 PRO HA  H   4.437 0.000 1
      162 263  28 PRO HB2 H   1.942 0.000 2
      163 263  28 PRO HB3 H   2.297 0.000 2
      164 263  28 PRO C   C 177.116 0.000 1
      165 263  28 PRO CA  C  63.531 0.000 1
      166 263  28 PRO CB  C  32.060 0.000 1
      167 264  29 SER H   H   8.724 0.001 1
      168 264  29 SER CA  C  58.659 0.000 1
      169 264  29 SER CB  C  63.927 0.000 1
      170 264  29 SER N   N 116.241 0.006 1
      171 265  30 ASN HA  H   4.710 0.000 1
      172 265  30 ASN HB2 H   2.819 0.000 1
      173 265  30 ASN C   C 175.124 0.000 1
      174 265  30 ASN CA  C  53.301 0.000 1
      175 265  30 ASN CB  C  38.713 0.000 1
      176 266  31 LYS H   H   8.197 0.001 1
      177 266  31 LYS HA  H   4.324 0.000 1
      178 266  31 LYS HB2 H   1.705 0.000 2
      179 266  31 LYS HB3 H   1.830 0.000 2
      180 266  31 LYS C   C 176.474 0.000 1
      181 266  31 LYS CA  C  56.433 0.007 1
      182 266  31 LYS CB  C  32.964 0.005 1
      183 266  31 LYS N   N 121.640 0.019 1
      184 267  32 VAL H   H   8.099 0.004 1
      185 267  32 VAL HA  H   4.075 0.000 1
      186 267  32 VAL HB  H   2.060 0.000 1
      187 267  32 VAL C   C 176.094 0.000 1
      188 267  32 VAL CA  C  62.378 0.002 1
      189 267  32 VAL CB  C  32.712 0.055 1
      190 267  32 VAL N   N 121.546 0.046 1
      191 268  33 LYS H   H   8.408 0.002 1
      192 268  33 LYS HA  H   4.345 0.000 1
      193 268  33 LYS HB2 H   1.754 0.000 2
      194 268  33 LYS HB3 H   1.835 0.000 2
      195 268  33 LYS C   C 176.309 0.000 1
      196 268  33 LYS CA  C  56.340 0.002 1
      197 268  33 LYS CB  C  33.025 0.027 1
      198 268  33 LYS N   N 125.618 0.024 1
      199 269  34 SER H   H   8.315 0.003 1
      200 269  34 SER HA  H   4.435 0.000 1
      201 269  34 SER HB2 H   3.814 0.000 1
      202 269  34 SER C   C 173.730 0.000 1
      203 269  34 SER CA  C  58.062 0.029 1
      204 269  34 SER CB  C  64.017 0.012 1
      205 269  34 SER N   N 117.755 0.033 1
      206 270  35 ASP H   H   8.424 0.001 1
      207 270  35 ASP CA  C  52.403 0.000 1
      208 270  35 ASP CB  C  41.158 0.000 1
      209 270  35 ASP N   N 123.782 0.032 1
      210 271  36 PRO HA  H   4.393 0.000 1
      211 271  36 PRO HB2 H   2.304 0.000 2
      212 271  36 PRO HB3 H   1.935 0.000 2
      213 271  36 PRO C   C 177.317 0.000 1
      214 271  36 PRO CA  C  63.770 0.000 1
      215 271  36 PRO CB  C  32.071 0.000 1
      216 272  37 GLN H   H   8.451 0.002 1
      217 272  37 GLN HA  H   4.265 0.000 1
      218 272  37 GLN HB2 H   2.015 0.000 2
      219 272  37 GLN HB3 H   2.118 0.000 2
      220 272  37 GLN C   C 176.297 0.000 1
      221 272  37 GLN CA  C  56.196 0.006 1
      222 272  37 GLN CB  C  29.146 0.016 1
      223 272  37 GLN N   N 119.014 0.028 1
      224 273  38 ARG H   H   8.157 0.003 1
      225 273  38 ARG HA  H   4.247 0.000 1
      226 273  38 ARG HB2 H   1.759 0.000 1
      227 273  38 ARG CA  C  56.317 0.000 1
      228 273  38 ARG CB  C  30.510 0.000 1
      229 273  38 ARG N   N 121.371 0.082 1
      230 274  39 MET H   H   8.345 0.001 1
      231 274  39 MET HA  H   4.423 0.000 1
      232 274  39 MET HB2 H   2.062 0.000 1
      233 274  39 MET C   C 176.196 0.000 1
      234 274  39 MET CA  C  56.028 0.000 1
      235 274  39 MET N   N 121.238 0.037 1
      236 275  40 ASN H   H   8.475 0.009 1
      237 275  40 ASN HA  H   4.664 0.000 1
      238 275  40 ASN HB2 H   2.744 0.000 2
      239 275  40 ASN HB3 H   2.842 0.000 2
      240 275  40 ASN C   C 174.972 0.000 1
      241 275  40 ASN CA  C  53.564 0.044 1
      242 275  40 ASN CB  C  38.746 0.010 1
      243 275  40 ASN N   N 119.174 0.053 1
      244 276  41 GLU H   H   8.211 0.003 1
      245 276  41 GLU HA  H   4.296 0.000 1
      246 276  41 GLU HB2 H   1.921 0.000 2
      247 276  41 GLU HB3 H   2.033 0.000 2
      248 276  41 GLU C   C 176.188 0.000 1
      249 276  41 GLU CA  C  56.457 0.004 1
      250 276  41 GLU CB  C  30.457 0.023 1
      251 276  41 GLU N   N 120.673 0.083 1
      252 277  42 GLN H   H   8.408 0.001 1
      253 277  42 GLN CA  C  53.890 0.000 1
      254 277  42 GLN CB  C  28.743 0.000 1
      255 277  42 GLN N   N 122.555 0.011 1
      256 278  43 PRO HA  H   4.398 0.000 1
      257 278  43 PRO HB2 H   2.283 0.000 2
      258 278  43 PRO HB3 H   1.868 0.000 2
      259 278  43 PRO CA  C  63.311 0.000 1
      260 278  43 PRO CB  C  32.061 0.000 1
      261 279  44 ARG H   H   8.428 0.001 1
      262 279  44 ARG CA  C  56.355 0.000 1
      263 279  44 ARG CB  C  30.809 0.000 1
      264 279  44 ARG N   N 121.344 0.076 1
      265 280  45 GLN HA  H   4.233 0.000 1
      266 280  45 GLN HB2 H   1.930 0.000 1
      267 280  45 GLN C   C 175.738 0.000 1
      268 280  45 GLN CA  C  55.953 0.000 1
      269 280  45 GLN CB  C  29.369 0.000 1
      270 281  46 LEU H   H   8.221 0.001 1
      271 281  46 LEU HA  H   4.218 0.000 1
      272 281  46 LEU HB2 H   1.282 0.000 2
      273 281  46 LEU HB3 H   1.464 0.000 2
      274 281  46 LEU C   C 177.229 0.000 1
      275 281  46 LEU CA  C  55.459 0.090 1
      276 281  46 LEU CB  C  42.247 0.031 1
      277 281  46 LEU N   N 123.165 0.023 1
      278 282  47 PHE H   H   8.131 0.001 1
      279 282  47 PHE HA  H   4.499 0.000 1
      280 282  47 PHE HB2 H   3.020 0.000 1
      281 282  47 PHE C   C 175.789 0.000 1
      282 282  47 PHE CA  C  58.293 0.048 1
      283 282  47 PHE CB  C  39.245 0.036 1
      284 282  47 PHE N   N 119.612 0.023 1
      285 283  48 TRP H   H   7.913 0.001 1
      286 283  48 TRP HA  H   4.523 0.000 1
      287 283  48 TRP HB2 H   3.234 0.000 1
      288 283  48 TRP C   C 176.332 0.000 1
      289 283  48 TRP CA  C  57.744 0.000 1
      290 283  48 TRP CB  C  29.548 0.000 1
      291 283  48 TRP N   N 121.525 0.011 1
      292 284  49 GLU H   H   8.145 0.001 1
      293 284  49 GLU HA  H   4.066 0.000 1
      294 284  49 GLU HB2 H   1.925 0.000 2
      295 284  49 GLU HB3 H   1.849 0.000 2
      296 284  49 GLU C   C 176.669 0.000 1
      297 284  49 GLU CA  C  57.280 0.044 1
      298 284  49 GLU CB  C  30.133 0.015 1
      299 284  49 GLU N   N 121.722 0.045 1
      300 285  50 LYS H   H   8.079 0.002 1
      301 285  50 LYS HA  H   4.148 0.000 1
      302 285  50 LYS HB2 H   1.736 0.000 1
      303 285  50 LYS C   C 177.012 0.000 1
      304 285  50 LYS CA  C  56.965 0.043 1
      305 285  50 LYS CB  C  32.549 0.015 1
      306 285  50 LYS N   N 121.315 0.050 1
      307 286  51 ARG H   H   8.145 0.007 1
      308 286  51 ARG HA  H   4.264 0.000 1
      309 286  51 ARG HB2 H   1.767 0.000 1
      310 286  51 ARG C   C 176.584 0.000 1
      311 286  51 ARG CA  C  56.603 0.000 1
      312 286  51 ARG CB  C  30.428 0.000 1
      313 286  51 ARG N   N 121.124 0.088 1
      314 287  52 LEU H   H   8.135 0.002 1
      315 287  52 LEU HA  H   4.303 0.000 1
      316 287  52 LEU HB2 H   1.573 0.000 2
      317 287  52 LEU HB3 H   1.658 0.000 2
      318 287  52 LEU C   C 177.451 0.000 1
      319 287  52 LEU CA  C  55.416 0.053 1
      320 287  52 LEU CB  C  42.095 0.031 1
      321 287  52 LEU N   N 122.131 0.033 1
      322 288  53 GLN H   H   8.164 0.002 1
      323 288  53 GLN HA  H   4.278 0.000 1
      324 288  53 GLN HB2 H   2.010 0.000 2
      325 288  53 GLN HB3 H   2.111 0.000 2
      326 288  53 GLN C   C 176.410 0.000 1
      327 288  53 GLN CA  C  56.300 0.002 1
      328 288  53 GLN CB  C  29.388 0.010 1
      329 288  53 GLN N   N 120.107 0.017 1
      330 289  54 GLY H   H   8.336 0.001 1
      331 289  54 GLY HA2 H   3.946 0.000 1
      332 289  54 GLY C   C 174.103 0.000 1
      333 289  54 GLY CA  C  45.359 0.016 1
      334 289  54 GLY N   N 109.560 0.003 1
      335 290  55 LEU H   H   8.039 0.001 1
      336 290  55 LEU HA  H   4.409 0.000 1
      337 290  55 LEU HB2 H   1.625 0.000 1
      338 290  55 LEU C   C 177.530 0.000 1
      339 290  55 LEU CA  C  55.216 0.056 1
      340 290  55 LEU CB  C  42.589 0.030 1
      341 290  55 LEU N   N 121.457 0.007 1
      342 291  56 SER H   H   8.456 0.001 1
      343 291  56 SER HA  H   4.479 0.000 1
      344 291  56 SER HB2 H   3.891 0.000 1
      345 291  56 SER C   C 174.448 0.000 1
      346 291  56 SER CA  C  58.104 0.026 1
      347 291  56 SER CB  C  64.197 0.005 1
      348 291  56 SER N   N 116.744 0.004 1
      349 292  57 ALA H   H   8.430 0.001 1
      350 292  57 ALA HA  H   4.314 0.000 1
      351 292  57 ALA HB  H   1.409 0.000 1
      352 292  57 ALA C   C 178.058 0.000 1
      353 292  57 ALA CA  C  53.157 0.007 1
      354 292  57 ALA CB  C  19.090 0.005 1
      355 292  57 ALA N   N 125.884 0.020 1
      356 293  58 SER H   H   8.219 0.001 1
      357 293  58 SER HA  H   4.410 0.000 1
      358 293  58 SER HB2 H   3.859 0.000 1
      359 293  58 SER C   C 174.422 0.000 1
      360 293  58 SER CA  C  58.767 0.036 1
      361 293  58 SER CB  C  63.786 0.004 1
      362 293  58 SER N   N 113.931 0.004 1
      363 294  59 ASP H   H   8.213 0.001 1
      364 294  59 ASP HA  H   4.628 0.000 1
      365 294  59 ASP HB2 H   2.699 0.000 1
      366 294  59 ASP C   C 176.570 0.000 1
      367 294  59 ASP CA  C  54.768 0.002 1
      368 294  59 ASP CB  C  41.249 0.010 1
      369 294  59 ASP N   N 122.218 0.010 1
      370 295  60 VAL H   H   8.023 0.001 1
      371 295  60 VAL HA  H   4.136 0.000 1
      372 295  60 VAL HB  H   2.146 0.000 1
      373 295  60 VAL C   C 176.591 0.000 1
      374 295  60 VAL CA  C  62.931 0.050 1
      375 295  60 VAL CB  C  32.473 0.055 1
      376 295  60 VAL N   N 119.629 0.034 1
      377 296  61 THR H   H   8.143 0.001 1
      378 296  61 THR HA  H   4.249 0.000 1
      379 296  61 THR C   C 174.822 0.000 1
      380 296  61 THR CA  C  62.804 0.032 1
      381 296  61 THR CB  C  69.772 0.044 1
      382 296  61 THR N   N 117.149 0.012 1
      383 297  62 GLU H   H   8.314 0.005 1
      384 297  62 GLU HA  H   4.220 0.000 1
      385 297  62 GLU HB2 H   2.031 0.000 1
      386 297  62 GLU C   C 176.647 0.000 1
      387 297  62 GLU CA  C  57.152 0.055 1
      388 297  62 GLU CB  C  30.163 0.008 1
      389 297  62 GLU N   N 122.744 0.048 1
      390 298  63 GLN H   H   8.260 0.005 1
      391 298  63 GLN HA  H   4.266 0.000 1
      392 298  63 GLN HB2 H   2.079 0.000 2
      393 298  63 GLN HB3 H   1.973 0.000 2
      394 298  63 GLN C   C 176.284 0.000 1
      395 298  63 GLN CA  C  56.358 0.003 1
      396 298  63 GLN CB  C  29.239 0.060 1
      397 298  63 GLN N   N 120.590 0.032 1
      398 299  64 ILE H   H   8.128 0.008 1
      399 299  64 ILE HA  H   4.087 0.000 1
      400 299  64 ILE HB  H   1.850 0.000 1
      401 299  64 ILE C   C 176.456 0.000 1
      402 299  64 ILE CA  C  61.728 0.036 1
      403 299  64 ILE CB  C  38.475 0.020 1
      404 299  64 ILE N   N 122.302 0.040 1
      405 300  65 ILE H   H   8.213 0.001 1
      406 300  65 ILE HA  H   4.078 0.000 1
      407 300  65 ILE HB  H   1.860 0.000 1
      408 300  65 ILE C   C 176.541 0.000 1
      409 300  65 ILE CA  C  61.669 0.000 1
      410 300  65 ILE CB  C  38.240 0.071 1
      411 300  65 ILE N   N 124.897 0.039 1
      412 301  66 LYS H   H   8.315 0.001 1
      413 301  66 LYS HA  H   4.358 0.000 1
      414 301  66 LYS HB2 H   1.789 0.000 2
      415 301  66 LYS HB3 H   1.842 0.000 2
      416 301  66 LYS C   C 176.919 0.000 1
      417 301  66 LYS CA  C  56.743 0.050 1
      418 301  66 LYS CB  C  32.954 0.019 1
      419 301  66 LYS N   N 124.655 0.011 1
      420 302  67 THR H   H   8.076 0.002 1
      421 302  67 THR HA  H   4.467 0.000 1
      422 302  67 THR HB  H   4.240 0.000 1
      423 302  67 THR C   C 174.533 0.000 1
      424 302  67 THR CA  C  62.220 0.080 1
      425 302  67 THR CB  C  69.831 0.076 1
      426 302  67 THR N   N 114.977 0.030 1
      427 303  68 MET H   H   8.273 0.007 1
      428 303  68 MET HA  H   4.594 0.000 1
      429 303  68 MET HB2 H   2.074 0.000 1
      430 303  68 MET C   C 175.738 0.000 1
      431 303  68 MET CA  C  55.654 0.057 1
      432 303  68 MET CB  C  32.868 0.039 1
      433 303  68 MET N   N 122.175 0.049 1
      434 304  69 GLU H   H   8.265 0.005 1
      435 304  69 GLU HA  H   4.301 0.000 1
      436 304  69 GLU HB2 H   1.912 0.000 2
      437 304  69 GLU HB3 H   2.008 0.000 2
      438 304  69 GLU C   C 176.006 0.000 1
      439 304  69 GLU CA  C  56.184 0.013 1
      440 304  69 GLU CB  C  30.427 0.028 1
      441 304  69 GLU N   N 122.123 0.094 1
      442 305  70 LEU H   H   8.284 0.001 1
      443 305  70 LEU CA  C  53.144 0.000 1
      444 305  70 LEU CB  C  41.652 0.000 1
      445 305  70 LEU N   N 125.006 0.014 1
      446 306  71 PRO HA  H   4.412 0.000 1
      447 306  71 PRO HB2 H   2.303 0.000 2
      448 306  71 PRO HB3 H   1.872 0.000 2
      449 306  71 PRO C   C 176.958 0.000 1
      450 306  71 PRO CA  C  63.070 0.000 1
      451 306  71 PRO CB  C  32.030 0.000 1
      452 307  72 LYS H   H   8.452 0.002 1
      453 307  72 LYS HA  H   4.255 0.000 1
      454 307  72 LYS HB2 H   1.795 0.000 1
      455 307  72 LYS C   C 177.444 0.000 1
      456 307  72 LYS CA  C  56.671 0.048 1
      457 307  72 LYS CB  C  33.018 0.009 1
      458 307  72 LYS N   N 121.746 0.025 1
      459 308  73 GLY H   H   8.416 0.001 1
      460 308  73 GLY HA2 H   3.943 0.000 1
      461 308  73 GLY C   C 174.163 0.000 1
      462 308  73 GLY CA  C  45.318 0.015 1
      463 308  73 GLY N   N 109.311 0.048 1
      464 309  74 LEU H   H   8.105 0.002 1
      465 309  74 LEU HA  H   4.362 0.000 1
      466 309  74 LEU HB2 H   1.608 0.000 1
      467 309  74 LEU C   C 177.421 0.000 1
      468 309  74 LEU CA  C  55.138 0.000 1
      469 309  74 LEU CB  C  42.388 0.000 1
      470 309  74 LEU N   N 121.498 0.009 1
      471 310  75 GLN H   H   8.372 0.001 1
      472 310  75 GLN HA  H   4.329 0.000 1
      473 310  75 GLN HB2 H   2.010 0.000 2
      474 310  75 GLN HB3 H   2.120 0.000 2
      475 310  75 GLN C   C 176.394 0.000 1
      476 310  75 GLN CA  C  56.047 0.009 1
      477 310  75 GLN CB  C  29.408 0.009 1
      478 310  75 GLN N   N 120.843 0.005 1
      479 311  76 GLY H   H   8.407 0.001 1
      480 311  76 GLY HA2 H   3.958 0.000 1
      481 311  76 GLY C   C 173.874 0.000 1
      482 311  76 GLY CA  C  45.342 0.020 1
      483 311  76 GLY N   N 110.181 0.006 1
      484 312  77 VAL H   H   7.951 0.001 1
      485 312  77 VAL HA  H   4.226 0.000 1
      486 312  77 VAL HB  H   2.115 0.000 1
      487 312  77 VAL C   C 176.355 0.000 1
      488 312  77 VAL CA  C  61.989 0.031 1
      489 312  77 VAL CB  C  32.853 0.000 1
      490 312  77 VAL N   N 118.281 0.011 1
      491 313  78 GLY H   H   8.377 0.001 1
      492 313  78 GLY CA  C  44.478 0.000 1
      493 313  78 GLY N   N 112.428 0.009 1
      494 314  79 PRO HA  H   4.443 0.000 1
      495 314  79 PRO HB2 H   1.987 0.000 2
      496 314  79 PRO HB3 H   2.277 0.000 2
      497 314  79 PRO C   C 177.759 0.000 1
      498 314  79 PRO CA  C  63.502 0.000 1
      499 314  79 PRO CB  C  32.078 0.000 1
      500 315  80 GLY H   H   8.590 0.001 1
      501 315  80 GLY HA2 H   3.985 0.000 1
      502 315  80 GLY C   C 174.309 0.000 1
      503 315  80 GLY CA  C  45.265 0.014 1
      504 315  80 GLY N   N 109.861 0.005 1
      505 316  81 SER H   H   8.165 0.001 1
      506 316  81 SER HA  H   4.441 0.000 1
      507 316  81 SER HB2 H   3.858 0.000 1
      508 316  81 SER C   C 174.405 0.000 1
      509 316  81 SER CA  C  58.497 0.071 1
      510 316  81 SER CB  C  64.048 0.002 1
      511 316  81 SER N   N 115.430 0.013 1
      512 317  82 ASN H   H   8.550 0.001 1
      513 317  82 ASN HA  H   4.748 0.000 1
      514 317  82 ASN HB2 H   2.772 0.000 2
      515 317  82 ASN HB3 H   2.847 0.000 2
      516 317  82 ASN C   C 174.895 0.000 1
      517 317  82 ASN CA  C  53.414 0.031 1
      518 317  82 ASN CB  C  39.012 0.030 1
      519 317  82 ASN N   N 120.550 0.012 1
      520 318  83 ASP H   H   8.251 0.001 1
      521 318  83 ASP HA  H   4.573 0.000 1
      522 318  83 ASP HB2 H   2.623 0.000 2
      523 318  83 ASP HB3 H   2.737 0.000 2
      524 318  83 ASP C   C 176.707 0.000 1
      525 318  83 ASP CA  C  54.823 0.000 1
      526 318  83 ASP CB  C  41.045 0.028 1
      527 318  83 ASP N   N 120.535 0.009 1
      528 319  84 GLU H   H   8.538 0.001 1
      529 319  84 GLU HA  H   4.239 0.000 1
      530 319  84 GLU HB2 H   2.000 0.000 2
      531 319  84 GLU HB3 H   2.108 0.000 2
      532 319  84 GLU C   C 177.397 0.000 1
      533 319  84 GLU CA  C  57.629 0.004 1
      534 319  84 GLU CB  C  29.866 0.004 1
      535 319  84 GLU N   N 122.013 0.009 1
      536 320  85 THR H   H   8.265 0.001 1
      537 320  85 THR HA  H   4.217 0.000 1
      538 320  85 THR C   C 175.221 0.000 1
      539 320  85 THR CA  C  63.298 0.055 1
      540 320  85 THR CB  C  69.508 0.041 1
      541 320  85 THR N   N 114.850 0.005 1
      542 321  86 LEU H   H   8.015 0.002 1
      543 321  86 LEU HA  H   4.314 0.000 1
      544 321  86 LEU HB2 H   1.624 0.000 2
      545 321  86 LEU HB3 H   1.698 0.000 2
      546 321  86 LEU C   C 177.747 0.000 1
      547 321  86 LEU CA  C  55.852 0.020 1
      548 321  86 LEU CB  C  42.105 0.029 1
      549 321  86 LEU N   N 123.793 0.031 1
      550 322  87 LEU H   H   8.088 0.002 1
      551 322  87 LEU HA  H   4.298 0.000 1
      552 322  87 LEU HB2 H   1.590 0.000 2
      553 322  87 LEU HB3 H   1.687 0.000 2
      554 322  87 LEU C   C 177.947 0.000 1
      555 322  87 LEU CA  C  55.771 0.007 1
      556 322  87 LEU CB  C  42.107 0.035 1
      557 322  87 LEU N   N 121.659 0.028 1
      558 323  88 SER H   H   8.102 0.000 1
      559 323  88 SER HA  H   4.380 0.000 1
      560 323  88 SER HB2 H   3.895 0.000 1
      561 323  88 SER C   C 174.744 0.000 1
      562 323  88 SER CA  C  58.837 0.003 1
      563 323  88 SER CB  C  63.694 0.014 1
      564 323  88 SER N   N 115.538 0.008 1
      565 324  89 ALA H   H   8.173 0.005 1
      566 324  89 ALA HA  H   4.334 0.000 1
      567 324  89 ALA HB  H   1.425 0.000 1
      568 324  89 ALA C   C 178.317 0.000 1
      569 324  89 ALA CA  C  53.132 0.016 1
      570 324  89 ALA CB  C  19.029 0.001 1
      571 324  89 ALA N   N 125.718 0.043 1
      572 325  90 VAL H   H   7.945 0.001 1
      573 325  90 VAL HA  H   4.021 0.000 1
      574 325  90 VAL HB  H   2.091 0.000 1
      575 325  90 VAL C   C 176.519 0.000 1
      576 325  90 VAL CA  C  62.975 0.034 1
      577 325  90 VAL CB  C  32.571 0.097 1
      578 325  90 VAL N   N 118.492 0.027 1
      579 326  91 ALA H   H   8.232 0.002 1
      580 326  91 ALA HA  H   4.279 0.000 1
      581 326  91 ALA HB  H   1.420 0.000 1
      582 326  91 ALA C   C 178.316 0.000 1
      583 326  91 ALA CA  C  53.186 0.006 1
      584 326  91 ALA CB  C  18.940 0.003 1
      585 326  91 ALA N   N 126.375 0.014 1
      586 327  92 SER H   H   8.175 0.001 1
      587 327  92 SER HA  H   4.357 0.000 1
      588 327  92 SER HB2 H   3.883 0.000 1
      589 327  92 SER C   C 174.723 0.000 1
      590 327  92 SER CA  C  58.856 0.028 1
      591 327  92 SER CB  C  63.747 0.018 1
      592 327  92 SER N   N 114.429 0.010 1
      593 328  93 ALA H   H   8.150 0.002 1
      594 328  93 ALA HA  H   4.309 0.000 1
      595 328  93 ALA HB  H   1.386 0.000 1
      596 328  93 ALA C   C 177.769 0.000 1
      597 328  93 ALA CA  C  52.773 0.027 1
      598 328  93 ALA CB  C  19.008 0.003 1
      599 328  93 ALA N   N 125.410 0.101 1
      600 329  94 LEU H   H   7.990 0.001 1
      601 329  94 LEU HA  H   4.273 0.000 1
      602 329  94 LEU HB2 H   1.577 0.000 1
      603 329  94 LEU C   C 177.361 0.000 1
      604 329  94 LEU CA  C  55.465 0.003 1
      605 329  94 LEU CB  C  42.390 0.037 1
      606 329  94 LEU N   N 119.990 0.006 1
      607 330  95 HIS H   H   8.237 0.006 1
      608 330  95 HIS HA  H   4.719 0.000 1
      609 330  95 HIS HB2 H   3.131 0.000 2
      610 330  95 HIS HB3 H   3.221 0.000 2
      611 330  95 HIS C   C 175.296 0.000 1
      612 330  95 HIS CA  C  55.946 0.000 1
      613 330  95 HIS CB  C  30.051 0.001 1
      614 330  95 HIS N   N 119.469 0.081 1
      615 331  96 THR H   H   8.064 0.001 1
      616 331  96 THR HA  H   4.369 0.000 1
      617 331  96 THR HB  H   4.241 0.000 1
      618 331  96 THR C   C 174.516 0.000 1
      619 331  96 THR CA  C  61.862 0.000 1
      620 331  96 THR CB  C  69.888 0.000 1
      621 331  96 THR N   N 115.082 0.033 1
      622 332  97 SER H   H   8.373 0.002 1
      623 332  97 SER HA  H   4.520 0.000 1
      624 332  97 SER HB2 H   3.900 0.000 1
      625 332  97 SER C   C 174.475 0.000 1
      626 332  97 SER CA  C  58.379 0.065 1
      627 332  97 SER CB  C  63.991 0.003 1
      628 332  97 SER N   N 117.946 0.011 1
      629 333  98 SER H   H   8.329 0.002 1
      630 333  98 SER HA  H   4.485 0.000 1
      631 333  98 SER HB2 H   3.865 0.000 1
      632 333  98 SER C   C 173.680 0.000 1
      633 333  98 SER CA  C  58.171 0.000 1
      634 333  98 SER CB  C  63.994 0.000 1
      635 333  98 SER N   N 117.898 0.025 1
      636 334  99 ALA H   H   8.218 0.001 1
      637 334  99 ALA CA  C  50.651 0.000 1
      638 334  99 ALA CB  C  18.190 0.000 1
      639 334  99 ALA N   N 127.029 0.015 1
      640 335 100 PRO HA  H   4.443 0.000 1
      641 335 100 PRO HB2 H   1.868 0.000 2
      642 335 100 PRO HB3 H   2.266 0.000 2
      643 335 100 PRO C   C 176.998 0.000 1
      644 335 100 PRO CA  C  63.005 0.000 1
      645 335 100 PRO CB  C  31.923 0.000 1
      646 336 101 ILE H   H   8.329 0.001 1
      647 336 101 ILE HA  H   4.207 0.000 1
      648 336 101 ILE HB  H   1.871 0.000 1
      649 336 101 ILE C   C 176.686 0.000 1
      650 336 101 ILE CA  C  61.322 0.040 1
      651 336 101 ILE CB  C  38.621 0.039 1
      652 336 101 ILE N   N 121.242 0.041 1
      653 337 102 THR H   H   8.166 0.001 1
      654 337 102 THR HA  H   4.356 0.000 1
      655 337 102 THR HB  H   4.217 0.000 1
      656 337 102 THR C   C 175.000 0.000 1
      657 337 102 THR CA  C  61.973 0.029 1
      658 337 102 THR CB  C  69.937 0.029 1
      659 337 102 THR N   N 117.847 0.010 1
      660 338 103 GLY H   H   8.398 0.001 1
      661 338 103 GLY HA2 H   3.970 0.000 1
      662 338 103 GLY C   C 173.912 0.000 1
      663 338 103 GLY CA  C  45.284 0.012 1
      664 338 103 GLY N   N 111.104 0.043 1
      665 339 104 GLN H   H   8.223 0.001 1
      666 339 104 GLN HA  H   4.375 0.000 1
      667 339 104 GLN HB2 H   1.962 0.000 2
      668 339 104 GLN HB3 H   2.070 0.000 2
      669 339 104 GLN C   C 176.093 0.000 1
      670 339 104 GLN CA  C  55.757 0.004 1
      671 339 104 GLN CB  C  29.591 0.015 1
      672 339 104 GLN N   N 120.023 0.010 1
      673 340 105 VAL H   H   8.287 0.002 1
      674 340 105 VAL HA  H   4.149 0.000 1
      675 340 105 VAL HB  H   2.082 0.000 1
      676 340 105 VAL C   C 176.215 0.000 1
      677 340 105 VAL CA  C  62.343 0.005 1
      678 340 105 VAL CB  C  32.803 0.048 1
      679 340 105 VAL N   N 121.879 0.016 1
      680 341 106 SER H   H   8.402 0.001 1
      681 341 106 SER HA  H   4.439 0.000 1
      682 341 106 SER HB2 H   3.851 0.000 1
      683 341 106 SER C   C 174.184 0.000 1
      684 341 106 SER CA  C  58.231 0.051 1
      685 341 106 SER CB  C  63.945 0.006 1
      686 341 106 SER N   N 119.731 0.012 1
      687 342 107 ALA H   H   8.360 0.001 1
      688 342 107 ALA HA  H   4.319 0.000 1
      689 342 107 ALA HB  H   1.379 0.000 1
      690 342 107 ALA C   C 177.318 0.000 1
      691 342 107 ALA CA  C  52.446 0.031 1
      692 342 107 ALA CB  C  19.270 0.003 1
      693 342 107 ALA N   N 126.401 0.011 1
      694 343 108 ALA H   H   8.220 0.001 1
      695 343 108 ALA HA  H   4.307 0.000 1
      696 343 108 ALA HB  H   1.361 0.000 1
      697 343 108 ALA C   C 177.747 0.000 1
      698 343 108 ALA CA  C  52.455 0.009 1
      699 343 108 ALA CB  C  19.087 0.026 1
      700 343 108 ALA N   N 123.411 0.014 1
      701 344 109 VAL H   H   8.024 0.001 1
      702 344 109 VAL HA  H   4.074 0.000 1
      703 344 109 VAL HB  H   2.059 0.000 1
      704 344 109 VAL C   C 176.228 0.000 1
      705 344 109 VAL CA  C  62.316 0.010 1
      706 344 109 VAL CB  C  32.773 0.000 1
      707 344 109 VAL N   N 119.319 0.024 1
      708 345 110 GLU H   H   8.432 0.001 1
      709 345 110 GLU HA  H   4.247 0.000 1
      710 345 110 GLU HB2 H   1.929 0.000 2
      711 345 110 GLU HB3 H   2.002 0.000 2
      712 345 110 GLU C   C 176.261 0.000 1
      713 345 110 GLU CA  C  56.569 0.020 1
      714 345 110 GLU CB  C  30.250 0.021 1
      715 345 110 GLU N   N 124.649 0.009 1
      716 346 111 LYS H   H   8.334 0.002 1
      717 346 111 LYS HA  H   4.266 0.000 1
      718 346 111 LYS HB2 H   1.745 0.000 1
      719 346 111 LYS C   C 175.959 0.000 1
      720 346 111 LYS CA  C  56.247 0.034 1
      721 346 111 LYS CB  C  33.004 0.031 1
      722 346 111 LYS N   N 122.611 0.029 1
      723 347 112 ASN H   H   8.477 0.001 1
      724 347 112 ASN CA  C  51.152 0.000 1
      725 347 112 ASN CB  C  38.940 0.000 1
      726 347 112 ASN N   N 120.764 0.010 1
      727 348 113 PRO HA  H   4.300 0.000 1
      728 348 113 PRO HB2 H   2.235 0.000 2
      729 348 113 PRO HB3 H   1.919 0.000 2
      730 348 113 PRO C   C 176.633 0.000 1
      731 348 113 PRO CA  C  63.426 0.000 1
      732 348 113 PRO CB  C  32.074 0.000 1
      733 349 114 ALA H   H   8.192 0.001 1
      734 349 114 ALA HA  H   4.174 0.000 1
      735 349 114 ALA HB  H   1.256 0.000 1
      736 349 114 ALA C   C 177.965 0.000 1
      737 349 114 ALA CA  C  52.690 0.024 1
      738 349 114 ALA CB  C  18.781 0.012 1
      739 349 114 ALA N   N 122.936 0.011 1
      740 350 115 VAL H   H   7.792 0.001 1
      741 350 115 VAL HA  H   4.028 0.000 1
      742 350 115 VAL HB  H   2.017 0.000 1
      743 350 115 VAL C   C 175.823 0.000 1
      744 350 115 VAL CA  C  62.494 0.007 1
      745 350 115 VAL CB  C  32.728 0.018 1
      746 350 115 VAL N   N 117.829 0.004 1
      747 351 116 TRP H   H   8.010 0.000 1
      748 351 116 TRP HA  H   4.687 0.000 1
      749 351 116 TRP HB2 H   3.196 0.000 2
      750 351 116 TRP HB3 H   3.275 0.000 2
      751 351 116 TRP C   C 175.792 0.000 1
      752 351 116 TRP CA  C  57.038 0.011 1
      753 351 116 TRP CB  C  29.464 0.015 1
      754 351 116 TRP N   N 123.686 0.021 1
      755 352 117 LEU H   H   7.882 0.001 1
      756 352 117 LEU HA  H   4.287 0.000 1
      757 352 117 LEU HB2 H   1.487 0.000 1
      758 352 117 LEU C   C 176.548 0.000 1
      759 352 117 LEU CA  C  54.974 0.020 1
      760 352 117 LEU CB  C  42.621 0.044 1
      761 352 117 LEU N   N 123.902 0.008 1
      762 353 118 ASN H   H   8.225 0.001 1
      763 353 118 ASN HA  H   4.632 0.000 1
      764 353 118 ASN HB2 H   2.679 0.000 2
      765 353 118 ASN HB3 H   2.832 0.000 2
      766 353 118 ASN C   C 175.417 0.000 1
      767 353 118 ASN CA  C  53.318 0.001 1
      768 353 118 ASN CB  C  38.700 0.001 1
      769 353 118 ASN N   N 119.556 0.022 1
      770 354 119 THR H   H   8.042 0.002 1
      771 354 119 THR HA  H   4.377 0.000 1
      772 354 119 THR HB  H   4.308 0.000 1
      773 354 119 THR C   C 174.581 0.000 1
      774 354 119 THR CA  C  61.764 0.071 1
      775 354 119 THR CB  C  69.766 0.035 1
      776 354 119 THR N   N 113.884 0.016 1
      777 355 120 SER H   H   8.288 0.001 1
      778 355 120 SER HA  H   4.490 0.000 1
      779 355 120 SER HB2 H   3.877 0.000 1
      780 355 120 SER C   C 173.507 0.000 1
      781 355 120 SER CA  C  58.541 0.053 1
      782 355 120 SER CB  C  64.000 0.005 1
      783 355 120 SER N   N 118.347 0.009 1
      784 356 121 GLN H   H   7.995 0.001 1
      785 356 121 GLN CA  C  57.469 0.000 1
      786 356 121 GLN CB  C  30.414 0.000 1
      787 356 121 GLN N   N 126.939 0.014 1

   stop_

save_