BMRB Entry 7273

Title:
Solution structure of Jingzhaotoxin-III, a novel toxin inhibiting both Nav and Kv channels   PubMed: 17481690
Deposition date:
2006-08-24
Original release date:
2007-09-24
Authors:
Liao, Z.; Peng, K.; Liang, S.
Citation:

Citation: Liao, Z.; Peng, K.; Liang, S.. "Solution structure of Jingzhaotoxin-III, a peptide toxin inhibiting both Nav1.5 and Kv2.1 channels"  Toxicon 50, 135-143 (2007).

Assembly members:

Assembly members:
Jingzhaotoxin-3, polymer, 36 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Chinese spider   Taxonomy ID: 278060   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Chilobrachys Chilobrachys jingzhao

Experimental source:   Production method: purified from the natural source

Experimental source:

Natural source:   Common Name: Chinese spider   Taxonomy ID: 278060   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Chilobrachys Chilobrachys jingzhao

Experimental source:   Production method: purified from the natural source

Entity Sequences (FASTA):

Entity Sequences (FASTA):
Jingzhaotoxin-3: DGECGGFWWKCGRGKPPCCK GYACSKTWGWCAVEAP

Data sets:
Data typeCount
1H chemical shifts230

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1Jingzhaotoxin-31

Entities:

Entity 1, Jingzhaotoxin-3 36 residues - Formula weight is not available

1   ASPGLYGLUCYSGLYGLYPHETRPTRPLYS
2   CYSGLYARGGLYLYSPROPROCYSCYSLYS
3   GLYTYRALACYSSERLYSTHRTRPGLYTRP
4   CYSALAVALGLUALAPRO

Samples:

sample_1: Jingzhaotoxin-3 6 mM; deuterium sodium acetate buffer 20 mM; NaN3 0.002%; EDTA 0.01 mM; Sodium 3-(trimethylsilyl) propionate-2,2,3,3-d4 0.2 mM; H2O 90%; D2O 10%

sample_cond_1: ionic strength: 20 mM; pH: 4.0; pressure: 1 atm; temperature: 303 K

Experiments:

NameSampleSample stateSample conditions
DQF-COSYnot availablenot availablenot available
2D TOCSYnot availablenot availablenot available
2D NOESYnot availablenot availablenot available

Software:

X-PLOR vNIH 2.9.6 - refinement

FELIX v98.0 - data analysis

NMR spectrometers:

  • Bruker DRX 500 MHz