BMRB Entry 7150
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PDB ID: 2h7d
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full
BMRB Entry DOI: doi:10.13018/BMR7150
MolProbity Validation Chart
NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
All files associated with the entry
Citation: Wegener, Kate; Partridge, Anthony; Han, Jaewon; Pickford, A.; Liddington, Robert; Ginsberg, Mark; Campbell, Iain. "Structural basis of integrin activation by talin" Cell 128, 171-182 (2007).
PubMed: 17218263
Assembly members:
Talin_F3, polymer, 102 residues, 11649.3 Da.
Beta3integrin-PIPKIg chimeric peptide, polymer, 34 residues, 4269.8 Da.
Natural source: Common Name: Chicken Taxonomy ID: 9031 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Gallus gallus
Experimental source: Production method: recombinant technology Vector: pGex-6P2
Entity Sequences (FASTA):
Talin_F3: GPLGSGVSFFLVKEKMKGKN
KLVPRLLGITKESVMRVDEK
TKEVIQEWSLTNIKRWAASP
KSFTLDFGDYQDGYYSVQTT
EGEQIAQLIAGYIDIILKKK
KS
Beta3integrin-PIPKIg chimeric peptide: KLLITIHDRKEFAKFEEERA
RAKWVXSPLHYSAR
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 283 |
| 15N chemical shifts | 108 |
| 1H chemical shifts | 989 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | Talin F3 domain | 1 |
| 2 | Integrin/PIPKIg peptide | 2 |
Entities:
Entity 1, Talin F3 domain 102 residues - 11649.3 Da.
| 1 | GLY | PRO | LEU | GLY | SER | GLY | VAL | SER | PHE | PHE | ||||
| 2 | LEU | VAL | LYS | GLU | LYS | MET | LYS | GLY | LYS | ASN | ||||
| 3 | LYS | LEU | VAL | PRO | ARG | LEU | LEU | GLY | ILE | THR | ||||
| 4 | LYS | GLU | SER | VAL | MET | ARG | VAL | ASP | GLU | LYS | ||||
| 5 | THR | LYS | GLU | VAL | ILE | GLN | GLU | TRP | SER | LEU | ||||
| 6 | THR | ASN | ILE | LYS | ARG | TRP | ALA | ALA | SER | PRO | ||||
| 7 | LYS | SER | PHE | THR | LEU | ASP | PHE | GLY | ASP | TYR | ||||
| 8 | GLN | ASP | GLY | TYR | TYR | SER | VAL | GLN | THR | THR | ||||
| 9 | GLU | GLY | GLU | GLN | ILE | ALA | GLN | LEU | ILE | ALA | ||||
| 10 | GLY | TYR | ILE | ASP | ILE | ILE | LEU | LYS | LYS | LYS | ||||
| 11 | LYS | SER |
Entity 2, Integrin/PIPKIg peptide 34 residues - 4269.8 Da.
| 1 | LYS | LEU | LEU | ILE | THR | ILE | HIS | ASP | ARG | LYS | ||||
| 2 | GLU | PHE | ALA | LYS | PHE | GLU | GLU | GLU | ARG | ALA | ||||
| 3 | ARG | ALA | LYS | TRP | VAL | PTR | SER | PRO | LEU | HIS | ||||
| 4 | TYR | SER | ALA | ARG |
Related Database Links:
| PDB | 1KUP 1KUZ 2H7D 2H7E |
| GB | AAA36121 AAB71380 AHN82190 EAW57680 EAW57681 |
| REF | XP_005070100 XP_005369467 XP_005402305 XP_006970595 XP_007633842 |
Download HSQC peak lists in one of the following formats:
CSV: Backbone
or all simulated peaks
SPARKY: Backbone
or all simulated peaks