BMRB Entry 7110

Chem Shift validation: AVS_anomalous, AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR7110

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Title:
1H, 13C, 15N CHEMICAL SHIFT FOR CBP BROMODOMIAN
Deposition date:
2006-05-12
Original release date:
2006-06-28
Authors:
ZHOU, MING-MING
Citation:

Citation: Sachchidanand, .; Resnick-Silverman, Lois; Yan, Sherry; Mutjaba, Shiraz; Liu, Wen-jun; Zeng, Lei; Manfredi, James; Zhou, Ming-Ming. "Target structure-based discovery of small molecules that block human p53 and CREB binding protein association"  Chem. Biol. 13, 81-90 (2006).
PubMed: 16426974

Assembly members:

Assembly members:
CBP, polymer, 121 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: Purified from the natural source

Entity Sequences (FASTA):

Entity Sequences (FASTA):
CBP: GSHMRKKIFKPEELRQALMP TLEALYRQDPESLPFRQPVD PQLLGIPDYFDIVKNPMDLS TIKRKLDTGQYQEPWQYVDD VWLMFNNAWLYNRKTSRVYK FCSKLAEVFEQEIDPVMQSL G

Data sets:
Data typeCount
13C chemical shifts400
15N chemical shifts103
1H chemical shifts544

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1CBP BROMODOMAIN1

Entities:

Entity 1, CBP BROMODOMAIN 121 residues - Formula weight is not available

1   GLYSERHISMETARGLYSLYSILEPHELYS
2   PROGLUGLULEUARGGLNALALEUMETPRO
3   THRLEUGLUALALEUTYRARGGLNASPPRO
4   GLUSERLEUPROPHEARGGLNPROVALASP
5   PROGLNLEULEUGLYILEPROASPTYRPHE
6   ASPILEVALLYSASNPROMETASPLEUSER
7   THRILELYSARGLYSLEUASPTHRGLYGLN
8   TYRGLNGLUPROTRPGLNTYRVALASPASP
9   VALTRPLEUMETPHEASNASNALATRPLEU
10   TYRASNARGLYSTHRSERARGVALTYRLYS
11   PHECYSSERLYSLEUALAGLUVALPHEGLU
12   GLNGLUILEASPPROVALMETGLNSERLEU
13   GLY

Samples:

sample_1: CBP

conditions_1: pH: 6.5

Experiments:

NameSampleSample stateSample conditions
HNCACBsample_1not availableconditions_1
HN(CO)CACBsample_1not availableconditions_1
HCCH-TOCSYsample_1100% D2Oconditions_1
(H)C(CO)NH-TOCSYsample_1not availableconditions_1
15N-ed-NOESYsample_110% D2Oconditions_1
13C-ed_NOESYsample_1100% D2Oconditions_1
13C15N-filt-NOESYsample_1100% D2Oconditions_1

Software:

No software information available

NMR spectrometers:

  • Bruker avance 800 MHz
  • Bruker DRX 500 MHz

Related Database Links:

BMRB 17392 17393 6960
PDB
DBJ BAE06125 BAG65526 BAI45616
GB AAB28651 AAC51331 AAC51770 AAH72594 AAI72737
PRF 1923401A
REF NP_001020603 NP_001073315 NP_001157494 NP_001247644 NP_004371
SP P45481 Q6JHU9 Q92793
TPG DAA15549
AlphaFold P45481 Q6JHU9 Q92793

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks