BMRB Entry 5940

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PDB ID: 2arw
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR5940
MolProbity Validation Chart

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Nicholas Rego and David Koes
3Dmol.js: molecular visualization with WebGL
Bioinformatics (2015) 31 (8): 1322-1324 doi:10.1093/bioinformatics/btu829

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Title:

1H, 15N and 13C backbone assignment of the carboxyl terminal domain of the cytokine binding module of the interleukin-6 receptor (IL-6R)

Deposition date:

2003-09-09

Original release date:

2004-07-06

Authors:

Schwantner, Andreas; Dingley, Andrew; Ozbek, Suat; Rose-John, Stefan; Grotzinger, Joachim

Citation:

Citation: Schwantner, Andreas; Dingley, Andrew; Ozbek, Suat; Hecht, Oliver; Rose-John, Stefan; Grotzinger, Joachim. "Letter to the Editor: 1H, 15N, 13C Backbone Assignment of the Carboxyl Terminal Domain of the Cytokine Binding Module of the Interleukin-6 Receptor" J. Biomol. NMR 29, 407-408 (2004).

Assembly members:

Assembly members:
interleukin-6 receptor, polymer, 126 residues, 14500 Da.

Natural source:

Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens

Experimental source:

Experimental source: Production method: recombinant technology

Entity Sequences (FASTA):

Entity Sequences (FASTA):
interleukin-6 receptor: MGILQPDPPANITVTAVARN PRWLSVTWQDPHSWNSSFYR LRFELRYRAERSKTFTTWMV KDLQHHCVIHDAWSGLRHVV QLRAQEEFGQGEWSEWSPEA MGTPWTESRSPPAENEVSTP MQALTT

Data sets:

assigned_chemical_shifts
- chemical_shift_1

Data type	Count
1H chemical shifts	360
13C chemical shifts	393
15N chemical shifts	103

Additional metadata:

Assembly
Samples and Experiments
Software
Spectrometers
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Assembly:

Entity Assembly ID	Entity Name	Entity ID
1	interleukin-6 receptor	1

Entities:

Entity 1, interleukin-6 receptor 126 residues - 14500 Da.

1

MET

GLY

ILE

LEU

GLN

PRO

ASP

PRO

ALA

2

ASN

ILE

THR

VAL

THR

ALA

VAL

ALA

ARG

ASN

3

PRO

ARG

TRP

LEU

SER

VAL

THR

TRP

GLN

ASP

4

PRO

HIS

SER

TRP

ASN

SER

PHE

TYR

ARG

5

LEU

ARG

PHE

GLU

LEU

ARG

TYR

ARG

ALA

GLU

6

ARG

SER

LYS

THR

PHE

THR

TRP

MET

VAL

7

LYS

ASP

LEU

GLN

HIS

CYS

VAL

ILE

HIS

8

ASP

ALA

TRP

SER

GLY

LEU

ARG

HIS

VAL

9

GLN

LEU

ARG

ALA

GLN

GLU

PHE

GLY

GLN

10

GLY

GLU

TRP

SER

GLU

TRP

SER

PRO

GLU

ALA

11

MET

GLY

THR

PRO

TRP

THR

GLU

SER

ARG

SER

12

PRO

ALA

GLU

ASN

GLU

VAL

SER

THR

PRO

13

MET

GLN

ALA

LEU

THR

Samples:

sample_1: interleukin-6 receptor, [U-95% 13C; U-90% 15N], 1.0 mM

condition_1: pH: 5.0; temperature: 293 K

Experiments:

Name	Sample	Sample state	Sample conditions

Software:

No software information available

NMR spectrometers:

Varian INOVA 600 MHz

PDB	1N26 1P9M 2ARW
DBJ	BAD97302 BAF85702 BAG35601 BAI46031
EMBL	CAA31312 CAA41231
GB	AAH89410 AAI32685 AAI32687 AAX36842 ABK41906
PRF	1502360A
REF	NP_000556 NP_852004 XP_001114404 XP_002810148 XP_003308452
SP	P08887
AlphaFold	P08887