BMRB Entry 5501
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PDB ID:
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR5501
MolProbity Validation Chart
NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
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Citation: Hunter, H.; Fulton, D.; Ganz, T.; Vogel, H.. "The Solution Structure of Human Hepcidin, a Peptide Hormone with Antimicrobial
Activity that is Involved in Iron Uptake and Hereditary Hemochromatosis" J. Biol. Chem. 277, 37597-37603 (2002).
PubMed: 12138110
Assembly members:
hepicidin, polymer, 25 residues, Formula weight is not available
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: chemical synthesis
Entity Sequences (FASTA):
hepicidin: DTHFPICIFCCGCCHRSKCG
MCCKT
- assigned_chemical_shifts
| Data type | Count |
| 1H chemical shifts | 126 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | Hepcidin-25 | 1 |
Entities:
Entity 1, Hepcidin-25 25 residues - Formula weight is not available
| 1 | ASP | THR | HIS | PHE | PRO | ILE | CYS | ILE | PHE | CYS | ||||
| 2 | CYS | GLY | CYS | CYS | HIS | ARG | SER | LYS | CYS | GLY | ||||
| 3 | MET | CYS | CYS | LYS | THR |
Samples:
sample_1: hepicidin, [U-15N]-Gly,Phe,Ile, 1.6 mM; phosphate buffer 40 mM; H2O 90%; D2O 10%
sample_cond_1: pH: 3.5; pressure: 1 atm; temperature: 298 K
Experiments:
| Name | Sample | Sample state | Sample conditions |
|---|---|---|---|
| 2D NOESY | not available | not available | not available |
| 2D TOCSY | not available | not available | not available |
| Diffusion experiment | not available | not available | not available |
Software:
XWINNMR v2.6 - collection
CNS v1.1 - structure solution
NMRPipe v3.4 - processing
NMR spectrometers:
- Bruker AVANCE 700 MHz