BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 5264

Title: Solution Structure of Human beta-Defensin 3   PubMed: 11741980

Deposition date: 2002-01-23 Original release date: 2002-06-13

Authors: Schibli, D.; ., Hunter; ., .; ., D.; ., .; 7, .; H., 8

Citation: Schibli, D.; ., Hunter; ., .; ., D.; ., .; 5264, .; 8, 5264; , . "The Solution Structures of the Human beta-Defensins lead to a Better Understanding of the Potent Bactericidal Activity of HBD3 against Staphylococcus aureus"  J. Biol. Chem. 277, 8279-8289 (2002).

Assembly members:
Human beta-defensin 3, polymer, 45 residues, 5168.9 Da.

Natural source:   Common Name: not available   Taxonomy ID: 9606   Superkingdom: not available   Kingdom: not available   Genus/species: not available not available

Experimental source:   Production method: recombinant technology' . . . . . . . . . . . . . . . 'Produced by Peprotech (Rocky Hill, NJ).   Host organism: 5264

Entity Sequences (FASTA):
Human beta-defensin 3: GIINTLQKYYCRVRGGRCAV LSCLPKEEQIGKCSTRGRKC CRRKK

Data sets:
Data typeCount
1H chemical shifts279

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1Beta-defensin 31

Entities:

Entity 1, Beta-defensin 3 45 residues - 5168.9 Da.

1   GLY.52645.GLN.526411.
2   VAL.526417.ALA.526423.
3   PRO.526429.GLY.526435.
4   GLY.526441.ARG.5264

Samples:

sample_1: Human beta-defensin 3 0.36 mM; .; .

sample_2: Human beta-defensin 3 0.36 mM; .

sample_cond_1: pH: 4.00; 1: . 5264; 0.1: K

Experiments:

NameSampleSample stateSample conditions
2D NOESYnot availablenot availablenot available
not availablenot availablenot availablenot available
not availablenot availablenot availablenot available

Software:

XWINNMR v2.6 - collection

NMRPipe v1.8 - processing

NMRView v4.1.3 - data analysis

CNS v1.0 - refinement

Aria v1.0 - refinement

NMR spectrometers:

  • Bruker AVANCE 500 MHz
  • Varian INOVA 800 MHz

Related Database Links:

PDB
BAB40572 .
. beta-defensin-3 [Homo sapiens] . . . . 100.00 . . .
beta defensin 103 [Gorilla gorilla] .
100.00 67 100.00 5.09e-17
67 100.00
5.45e-17 .