BMRB Entry 52147

Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR52147

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Title:
RNA binding protein hMEX3B can specifically recognize HLA-A mRNA to promote tumor immune escape
Deposition date:
2023-09-25
Original release date:
2023-10-25
Authors:
Yang, Kanglong; Zhang, Liang; Zhang, Jiahai
Citation:

Citation: Yang, Kanglong; Chen, Guanglin; Yu, Fan; Fang, Xianyang; Zhang, Jiahai; Zhang, Zhiyong; Shi, Yunyu; Zhang, Liang. "Molecular mechanism of specific HLA-A mRNA recognition by the RNA-binding-protein hMEX3B to promote tumor immune escape"  Commun. Biol. 7, 158-158 (2024).
PubMed: 38326406

Assembly members:

Assembly members:
entity_1, polymer, 89 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET28a

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: DSEPRKKSVNMTECVPVPSS EHVAEIVGRQGCKIKALRAK TNTYIKTPVRGEEPVFVVTG RKEDVAMARREIISAAEHFS MIRASRNKN

Data sets:
Data typeCount
13C chemical shifts361
15N chemical shifts89
1H chemical shifts573

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1MEX3B KH1 domain1

Entities:

Entity 1, MEX3B KH1 domain 89 residues - Formula weight is not available

1   ASPSERGLUPROARGLYSLYSSERVALASN
2   METTHRGLUCYSVALPROVALPROSERSER
3   GLUHISVALALAGLUILEVALGLYARGGLN
4   GLYCYSLYSILELYSALALEUARGALALYS
5   THRASNTHRTYRILELYSTHRPROVALARG
6   GLYGLUGLUPROVALPHEVALVALTHRGLY
7   ARGLYSGLUASPVALALAMETALAARGARG
8   GLUILEILESERALAALAGLUHISPHESER
9   METILEARGALASERARGASNLYSASN

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SPARKY: Backbone or all simulated peaks