BMRB Entry 5186

Title:
1H, 13C, and 15N backbone assignment of the vascular endothelial growth factor receptor-binding domain
Deposition date:
2001-10-19
Original release date:
2002-05-07
Authors:
Pan, Borlan; Fairbrother, Wayne
Citation:

Citation: Pan, Borlan; Fairbrother, Wayne. "1H, 13C, and 15N Resonance Assignment of the Vascular Endothelial Growth Factor Receptor-binding Domain in Complex with a Receptor-blocking Peptide"  J. Biomol. NMR 22, 189-190 (2002).
PubMed: 11883783

Assembly members:

Assembly members:
vascular endothelial growth factor, polymer, 99 residues, 11625.4 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology

Entity Sequences (FASTA):

Data sets:
Data typeCount
1H chemical shifts184
13C chemical shifts260
15N chemical shifts85

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1VEGF subunit 11
2VEGF subunit 21

Entities:

Entity 1, VEGF subunit 1 99 residues - 11625.4 Da.

1   HISHISGLUVALVALLYSPHEMETASPVAL
2   TYRGLNARGSERTYRCYSHISPROILEGLU
3   THRLEUVALASPILEPHEGLNGLUTYRPRO
4   ASPGLUILEGLUTYRILEPHELYSPROSER
5   CYSVALPROLEUMETARGCYSGLYGLYCYS
6   CYSASNASPGLUGLYLEUGLUCYSVALPRO
7   THRGLUGLUSERASNILETHRMETGLNILE
8   METARGILELYSPROHISGLNGLYGLNHIS
9   ILEGLYGLUMETSERPHELEUGLNHISASN
10   LYSCYSGLUCYSARGPROLYSLYSASP

Samples:

Sample_1: vascular endothelial growth factor, [U-98% 13C; U-98% 15N], 1.0 mM

Sample_2: vascular endothelial growth factor, [U-98% 13C; U-98% 15N], 2.0 mM

Cond_1: pH: 7.0; temperature: 318 K

Experiments:

NameSampleSample stateSample conditions

Software:

No software information available

NMR spectrometers:

  • Bruker AMX 500 MHz
  • Bruker DRX 800 MHz

Related Database Links:

BMRB 5198
PDB
DBJ BAA78418 BAB68520 BAD92722 BAG70136 BAG70265
EMBL CAA09179 CAA44447 CAA57143 CAB82426 CAC19923
GB AAA35789 AAA36804 AAA36807 AAB47118 AAC63102
PRF 2105202A
REF NP_001003175 NP_001009854 NP_001020537 NP_001020538 NP_001020539
SP P15692 P49151 Q9MYV3
AlphaFold P15692 P49151 Q9MYV3

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks