BMRB Entry 51473

Title:
IL1R8   PubMed: 35889366
Deposition date:
2022-05-24
Original release date:
2022-08-08
Authors:
Lee, Eunjeong
Citation:

Citation: Lee, Eunjeong; Redzic, Jasmina; Nemkov, Travis; Saviola, Anthony; Dzieciatkowska, Monika; Hansen, Kirk; D'Alessandro, Angelo; Dinarello, Charles; Eisenmesser, Elan. "Human and Bacterial Toll-Interleukin Receptor Domains Exhibit Distinct Dynamic Features and Functions"  Molecules 27, 4494-4494 (2022).

Assembly members:

Assembly members:
entity_1, polymer, 150 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pet27

Experimental source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pet27

Data sets:
Data typeCount
13C chemical shifts369
15N chemical shifts125
1H chemical shifts125

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1IL1R81

Entities:

Entity 1, IL1R8 150 residues - Formula weight is not available

1   ASPGLYLYSLEUTYRASPALATYRVALSER
2   TYRSERASPCYSPROGLUASPARGLYSPHE
3   VALASNPHEILELEULYSPROGLNLEUGLU
4   ARGARGARGGLYTYRLYSLEUPHELEUASP
5   ASPARGASPLEULEUPROARGALAGLUPRO
6   SERALAASPLEULEUVALASNLEUSERARG
7   CYSARGARGLEUILEVALVALLEUSERASP
8   ALAPHELEUSERARGALATRPCYSSERHIS
9   SERPHEARGGLUGLYLEUCYSARGLEULEU
10   GLULEUTHRARGARGPROILEPHEILETHR
11   PHEGLUGLYGLNARGARGASPPROALAHIS
12   PROALALEUARGLEULEUARGGLNHISARG
13   HISLEUVALTHRLEULEULEUTRPARGPRO
14   GLYSERVALTHRPROSERSERASPPHETRP
15   LYSGLUVALGLNLEUALALEUPROARGLYS

Samples:

sample_1: IL1R8, [U-13C; U-15N], 1 mM; DTT 1 mM; HEPES 50 mM; sodium chloride 150 mM

sample_conditions_1: ionic strength: 150 mM; pH: 7.5; pressure: 1 atm; temperature: 303 K

Experiments:

NameSampleSample stateSample conditions
2D 1H-15N HSQCsample_1isotropicsample_conditions_1
3D HNCAsample_1isotropicsample_conditions_1
3D HNCACBsample_1isotropicsample_conditions_1
3D HN(CO)CAsample_1isotropicsample_conditions_1
3D HN(CO)CACBsample_1isotropicsample_conditions_1

Software:

CcpNMR - chemical shift assignment

NMR spectrometers:

  • Bruker Avance 600 MHz

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks