BMRB Entry 51313
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR51313
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NMR-STAR v3 text file.
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Citation: Malaga Gadea, Fabiana; Nikolova, Evgenia. "Structural Plasticity of Pioneer Factor Sox2 and DNA Bendability Modulate Nucleosome Engagement and Sox2-Oct4 Synergism" J. Mol. Biol. 435, 167916-167916 (2023).
PubMed: 36495920
Assembly members:
entity_1, polymer, 82 residues, Formula weight is not available
entity_2, polymer, 14 residues, Formula weight is not available
entity_3, polymer, 14 residues, Formula weight is not available
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli Vector: pET15
Entity Sequences (FASTA):
entity_1: GPDRVKRPMNAFMVWSRGQR
RKMAQENPKMHNSEISKRLG
AEWKLLSETEKRPFIDEAKR
LRALHMKEHPDAKYRPRRKT
KT
entity_2: GACTCTTTGTTTGG
entity_3: CCAAACAAAGAGTC
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 29 |
| 15N chemical shifts | 68 |
| 1H chemical shifts | 155 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | Sox2 HMG Y72A | 1 |
| 2 | DNA_strand_1 | 2 |
| 3 | DNA_strand_2 | 3 |
Entities:
Entity 1, Sox2 HMG Y72A 82 residues - Formula weight is not available
| 1 | GLY | PRO | ASP | ARG | VAL | LYS | ARG | PRO | MET | ASN | ||||
| 2 | ALA | PHE | MET | VAL | TRP | SER | ARG | GLY | GLN | ARG | ||||
| 3 | ARG | LYS | MET | ALA | GLN | GLU | ASN | PRO | LYS | MET | ||||
| 4 | HIS | ASN | SER | GLU | ILE | SER | LYS | ARG | LEU | GLY | ||||
| 5 | ALA | GLU | TRP | LYS | LEU | LEU | SER | GLU | THR | GLU | ||||
| 6 | LYS | ARG | PRO | PHE | ILE | ASP | GLU | ALA | LYS | ARG | ||||
| 7 | LEU | ARG | ALA | LEU | HIS | MET | LYS | GLU | HIS | PRO | ||||
| 8 | ASP | ALA | LYS | TYR | ARG | PRO | ARG | ARG | LYS | THR | ||||
| 9 | LYS | THR |
Entity 2, DNA_strand_1 14 residues - Formula weight is not available
| 1 | DG | DA | DC | DT | DC | DT | DT | DT | DG | DT | ||||
| 2 | DT | DT | DG | DG |
Entity 3, DNA_strand_2 14 residues - Formula weight is not available
| 1 | DC | DC | DA | DA | DA | DC | DA | DA | DA | DG | ||||
| 2 | DA | DG | DT | DC |
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